Olig005771.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Osmia lignaria
Gene Symbol
mecom-b
Assembly
GCA_012274295.1
Location
NW:1298399-1358359[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.013 0.92 9.3 0.6 2 23 278 300 277 300 0.92
2 9 0.11 7.9 6.4 0.1 1 23 307 330 307 330 0.93
3 9 9.5e-06 0.00066 19.2 1.5 1 23 336 363 336 364 0.93
4 9 3.1e-06 0.00021 20.7 2.6 1 23 370 392 370 392 0.95
5 9 2.6e-05 0.0018 17.8 4.1 1 23 398 420 398 420 0.99
6 9 0.00029 0.021 14.5 0.7 2 21 428 447 427 448 0.95
7 9 4.4e-09 3.1e-07 29.7 1.2 1 23 800 822 800 822 0.99
8 9 2.3e-07 1.6e-05 24.3 1.7 1 23 828 851 828 851 0.97
9 9 6.5e-06 0.00046 19.7 3.4 1 23 857 879 857 879 0.99

Sequence Information

Coding Sequence
ATGGAGGAGAACGGGTCGATTCGTGCCGGTAGCAACAGTTCCGGCATCGGCAGTCAGGTGTACAGGGAGCTGAAGAGCCTGCACTCCAACTCCACCATCGGCCACGATTTGTCCCAGGATTACAATCAGCAATCGAGGCCGTCCTATCAACGAGGTTACTCGCCCGCCATGGACAAGCAACAGCAACACTACGAGAAGGAACGACATCGAACAGCCTCGTCgaaggaggaagaaaagtGTTCGTGGGATTACTTGGAGAAGAGTGACAGAAAAGAGTACTCGAGATCGCGGGAGTCGTCGTACAGGAACGAAGCCTACCAGGACACGATGAAGCAAGAGCAGAAGGAGCAATCGAATCGCGAATGGGTGTCACCGGTGCCGGAGGTCGAGGTGGGAGGCAGCTCGGCCGATCCTCAGGTTCGAGCGCGAAAGGACATTCCACGGGGTGCAAGATTCGGCCCCTTTCTCGGCAAATGGGCGAGCGAACCTTTCAACCCCCGTTACGCATGGGAGgttcGTACCGCTGGAAGCGGTGTCAGGGGGTGGTTGGACGCATCCCACGAAACGAACAACTGGCTGAAATACATTCGCAGCGCCAACAGTCCGCACGCGGTTAATATGCGGCACGTGCTGATCGGCGGACAGATGGTGTACGAGGCCGTACGGGACATAGCGGCGGGTGAAGAGCTTCTTCTCGGTGTTCGAGAACCTCTTCAGCTGCAGGACATGCTTGGTGAAAATACGACCGAGGACAGAAGCGATAGAGAGACCGCCTCGCAACACAGCGGCACCGTTGACGAGGATAAAGAGGACGAGGAAGAGGGTGAGACCAGGTGCACCGTATGCGACAAGCCGTTCCAAGACATCGAACTATTGGACAGCCACCTGGTATCCTGTCACAGATATCCTGCGGAGCAACACCGCTGCGATACCTGTCCCCGTGCCTACGCCTGGCGACCTCTTCTAGTTCGTCATCGCGCGATCGTTCACGGTGATCTTCGAAATTATCCCTGTGAAAATTGTCCAAAGTCGGACAAACCGCAGGTCTTCACGGATCCGTCGAACCTGCAGCGTCACATCAGGACGCATCACGTGGGCGCGAGGAGTCACGCGTGCACCGAGTGCGGCAAAACGTTCGCCACCAGTTCCGGCCTGAAACAACACACCCATATCCACAGCAGCGTGAAACCGTTCCAGTGCGAGGTCTGCTTGAAGGCGTACACCCAGTTCTCCAATCTATGCCGGCACAAACGAATGCACGCGGACTGTCGCATGCAGATCAAGTGCGCTAAATGCGGACAGTCTTTCAGCACCGTCACCTCGTTGTCGAAGCACAAACGATTCTGTGATTCAACGCCACCGACCGGTCCACCAGGAGCCATGCCGCAATTACCGACCTCGGCACCGAGCCCTTTCCTCGTCTATCGACCTCCCGTCAGTCTACCGGGTAGTCTCCCATACTACCCGTCCAGTCTGATGGGCCCGTACCCAGGAATATTTCCAAACGCTCCGCACTTCTTGAACACCCCACTGTTGTTCCCGCCTAAGGTTGAGGAAGCCGAGAAGAGAAGCGACAGTCCGAAGAAGGAACGTTTCACCCCGCCAAGGGTGCTACCCCAGCACAGCAAAGTTTCTCCATCCACCGCCGAAGAAGCTACTTCGTCGTTCAGACCCTCTCCAGCTAGACCGCCTGTCCAGCCTACTCCAGAGAGCGACGACGATCCCTCGAAGAAGCGAAAAGTTGGCGGAAACAACGAGAAGAAGGTGGACTCTGAGCATAATTCAACAAACGCGAACGAAGAGACGACGGATCAACCTCTGGATCTGAGAGTCcaaacgaagaaacaaaaaacaacAGCGAATACCGCCGAGAGGAACAACCACAGTCCTTCGCCTGTTCCAGCACCGATGGAGGAAGCTCCACCGCCTCCTGAACCTCCCAAGCCCGAAGAAGAGGTCCACGCACCGATAGACGTCGATACCAAGGACGTACCCAGTAGTCTGCAACTGAGAACCAGTTTACCTGAACAACCGGTCACCAATACTCCGCCGCACATGGCTTACCCCAGACCCATTCATCCCATGTTCCTGGAGGCCATGTACCGCGGTCCAACGGGCAGTTTCCCAGGCTTTCCAGGCGGACCGCCTCCTGGAAGTGGCACGCCAGAGTCCAGGCTATTACCACCGCTCCAACCGTTCGAACCACCCCGTGGGCTTCCTTTTTTAGGGACGTTCATGAACGGGCTCAGCGGCGCTAGGCCAGGAGGCGGAGGATTCGACCTGCTTGCCAGGCCACCGTTGGGACCGTTCCCCGGTGTAAAGCCGTTTCAAGAGGCCGTAATCGCGCCCCATCACCATCACCATCCTCATCACGCTCACGGCAAGATGAAGGACCGATACTCCTGTAAGTTTTGTGGCAAGGTATTCCCCAGATCAGCCAATCTGACTAGACACCTGCGGACACATACCGGCGAGCAACCCTACAAGTGCAAGTACTGCGAGAGATCCTTCAGCATCTCCAGCAATCTCCAGAGACACGTTAGGAACATCCACGACAAACAGAGACCATTCAAGTGTCCCTTATGTGAGAGATGTTTCGGGCAACAGACCAATTTGGATAGACACTTAAAGAAACACGAAGCTGACGACGGCAGTGGAGTCGTCTCTGTGGCTGATTCACCAGGTAGTAGCAACGAGAACGAACGCGAGGACACGTATTTCGACGAAATCAGGTCGTTCATGGGCAAGGTAACGTACGGTGGTGAAGCAGGTTACGGGCTACCCCCTCACCCTGCTTACCTACCCAGCAGACTACACGAAATGCACGAGTCCAAGATGGAAACCGAGTACGACGAGGACGAAGACAGCGAGGAAGGAGTGTCCCCTTTAGACGAAACCGATGGATTGTCCCCCGTCGAGGCCAAGGAATCCACCCCACCCCCGCAGTACGATCTGAAGCTGAGGGAGAAGCAAGAAATGCTCAATAACAACACCGCCGAACCGGTCATCGAAATTTCTACATAG
Protein Sequence
MEENGSIRAGSNSSGIGSQVYRELKSLHSNSTIGHDLSQDYNQQSRPSYQRGYSPAMDKQQQHYEKERHRTASSKEEEKCSWDYLEKSDRKEYSRSRESSYRNEAYQDTMKQEQKEQSNREWVSPVPEVEVGGSSADPQVRARKDIPRGARFGPFLGKWASEPFNPRYAWEVRTAGSGVRGWLDASHETNNWLKYIRSANSPHAVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLVSCHRYPAEQHRCDTCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCLKAYTQFSNLCRHKRMHADCRMQIKCAKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTSAPSPFLVYRPPVSLPGSLPYYPSSLMGPYPGIFPNAPHFLNTPLLFPPKVEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKRKVGGNNEKKVDSEHNSTNANEETTDQPLDLRVQTKKQKTTANTAERNNHSPSPVPAPMEEAPPPPEPPKPEEEVHAPIDVDTKDVPSSLQLRTSLPEQPVTNTPPHMAYPRPIHPMFLEAMYRGPTGSFPGFPGGPPPGSGTPESRLLPPLQPFEPPRGLPFLGTFMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHPHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPVEAKESTPPPQYDLKLREKQEMLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01539779;
90% Identity
iTF_00118172;
80% Identity
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