Basic Information

Insect: Osmia bicornis
Gene Symbol: -
Assembly: GCA_907164935.1
Location: NC:9620360-9629796[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0029 0.18 12.7 2.6 2 23 175 196 174 196 0.96

2 26 0.0002 0.012 16.4 1.1 1 23 202 224 202 224 0.98

3 26 2.7e-06 0.00017 22.3 0.7 2 23 230 251 230 251 0.97

4 26 0.014 0.88 10.6 0.2 3 23 259 279 257 279 0.96

5 26 0.00013 0.0079 17.0 0.9 2 23 290 311 290 311 0.98

6 26 1.4e-06 8.7e-05 23.2 1.1 1 23 332 354 332 354 0.99

7 26 0.00011 0.0066 17.3 1.0 1 20 360 379 360 382 0.95

8 26 3.8e-05 0.0023 18.7 0.5 1 23 388 411 388 411 0.95

9 26 0.015 0.91 10.5 2.3 3 23 422 443 420 443 0.97

10 26 7e-06 0.00043 21.0 3.0 1 23 573 595 573 595 0.98

11 26 0.0005 0.031 15.2 2.9 1 23 629 651 629 651 0.99

12 26 0.34 21 6.3 2.0 1 23 657 679 657 679 0.96

13 26 0.02 1.2 10.1 7.1 1 23 775 797 775 797 0.98

14 26 6e-05 0.0037 18.1 4.0 1 23 803 825 803 825 0.98

15 26 3.2e-05 0.002 18.9 0.3 3 23 833 853 831 853 0.97

16 26 0.00077 0.047 14.6 7.6 1 23 859 881 859 881 0.98

17 26 0.3 18 6.4 1.0 2 23 1272 1293 1271 1293 0.96

18 26 0.0018 0.11 13.4 2.9 1 23 1299 1321 1299 1321 0.98

19 26 0.0029 0.18 12.8 2.2 2 23 1328 1349 1327 1349 0.96

20 26 2.1e-06 0.00013 22.6 1.4 2 23 1432 1453 1431 1453 0.98

21 26 0.007 0.43 11.6 3.7 1 23 1459 1481 1459 1481 0.98

22 26 2e-05 0.0012 19.6 2.1 1 23 1487 1509 1487 1509 0.98

23 26 0.00097 0.06 14.3 2.6 1 23 1515 1537 1515 1537 0.98

24 26 5.3e-06 0.00032 21.4 0.6 2 23 1771 1792 1770 1792 0.97

25 26 2.6e-05 0.0016 19.2 4.5 1 23 1798 1820 1798 1820 0.98

26 26 6.6e-07 4.1e-05 24.2 0.6 1 23 1826 1849 1826 1849 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0029	0.18	12.7	2.6	2	23	175	196	174	196	0.96
2	26	0.0002	0.012	16.4	1.1	1	23	202	224	202	224	0.98
3	26	2.7e-06	0.00017	22.3	0.7	2	23	230	251	230	251	0.97
4	26	0.014	0.88	10.6	0.2	3	23	259	279	257	279	0.96
5	26	0.00013	0.0079	17.0	0.9	2	23	290	311	290	311	0.98
6	26	1.4e-06	8.7e-05	23.2	1.1	1	23	332	354	332	354	0.99
7	26	0.00011	0.0066	17.3	1.0	1	20	360	379	360	382	0.95
8	26	3.8e-05	0.0023	18.7	0.5	1	23	388	411	388	411	0.95
9	26	0.015	0.91	10.5	2.3	3	23	422	443	420	443	0.97
10	26	7e-06	0.00043	21.0	3.0	1	23	573	595	573	595	0.98
11	26	0.0005	0.031	15.2	2.9	1	23	629	651	629	651	0.99
12	26	0.34	21	6.3	2.0	1	23	657	679	657	679	0.96
13	26	0.02	1.2	10.1	7.1	1	23	775	797	775	797	0.98
14	26	6e-05	0.0037	18.1	4.0	1	23	803	825	803	825	0.98
15	26	3.2e-05	0.002	18.9	0.3	3	23	833	853	831	853	0.97
16	26	0.00077	0.047	14.6	7.6	1	23	859	881	859	881	0.98
17	26	0.3	18	6.4	1.0	2	23	1272	1293	1271	1293	0.96
18	26	0.0018	0.11	13.4	2.9	1	23	1299	1321	1299	1321	0.98
19	26	0.0029	0.18	12.8	2.2	2	23	1328	1349	1327	1349	0.96
20	26	2.1e-06	0.00013	22.6	1.4	2	23	1432	1453	1431	1453	0.98
21	26	0.007	0.43	11.6	3.7	1	23	1459	1481	1459	1481	0.98
22	26	2e-05	0.0012	19.6	2.1	1	23	1487	1509	1487	1509	0.98
23	26	0.00097	0.06	14.3	2.6	1	23	1515	1537	1515	1537	0.98
24	26	5.3e-06	0.00032	21.4	0.6	2	23	1771	1792	1770	1792	0.97
25	26	2.6e-05	0.0016	19.2	4.5	1	23	1798	1820	1798	1820	0.98
26	26	6.6e-07	4.1e-05	24.2	0.6	1	23	1826	1849	1826	1849	0.97

Sequence Information

Coding Sequence: atGTTGACGCGGCATAATATAATCACAGAATCACCTCACGTTGAGGCTATACCGATTAATCTTGTTACCACCGAGGATGGTCGAACGCTTTTGGCAGTGACAGAACATAAAGATGGTATGATGGAAATCGTTGCAACTCCAGTTACGCTCATCGGTCAAAACGGTTCACCTACTTCGTTGGTTGATGTAAAAAACTTTAATGAAAACTTTATACTGCACTCTCCTATTTTTCAACTGAATATAGAAGATATCGTTGATGGGACAGATCTACAACAGCCTACAGAAAATGTTGAACCTGGTACTGCTACTAACGACAGATTAAAGTCACAAATGTCCATGGAAGCAAAGTGCAAGACAGAAACTAGTTGGGAATACCGATCTCCTTTGCAAAATGATTTAACAACAATTAACAAACAGGATGAAAGCTCTGTGCAAAAGTCAGTAAACGACGGTGTCAAAAGAAGTAGCCCTGGAAGACCTAAGAAAACTGCAACAGTTTCCTTACAAGGTACAGAATGTTTAAGATGCGACATATGCCATCAAGAATTTGTCAAACGGACTTTATATCGGAAACACATGGAAAATCATGCGGAAGAGAAACCACATCGGTGTCCAAAATGTTCTGCATCGTTCAATGTACCGACCAATTTTACTCTTCATATGGCGACTCATAATACGGGCGAACCAAAGTGCCCAGAATGTGGGAAAAAATTTACAAGAATGGCTAGTTTAAAATCTCATATGCTGCTACacgagaaagaggaaaatttGTTCTGTACAGAATGCGAAGACGCTTTTTCAACTAAAGCTCAATTGGATGCACATTTGAAACTTCACGGAGAAAAGTGGGCGACGGAAGAGGCGCGAAAGTGTAAGCTATGCAATAAACAATTTAGTCAACCGGCTTTGTACAGGCTTCATATTCGTGAACATTACAGGTTGCAGACTAAAGTGGCAAAACAGacgaaaaaaggaacgaaaCATAAAACGGTATATAAATGTACGATATGCTTAAAGTCTTTCCAGAAACCGAGTCAATTAATGCGCCATATCAGAGTGCATACCGGTGAAAAACCTTTCAAATGTACCGTGTGCAGTCGTGCATTTACACAAAAAAGTTCGCTGCAGATTCATACGTGGCAGCACAATGGTATTCGGCCTCATGCTTGCGAACTTTGTAACGCGAAATTCAGTCAGAAAGGTAATTTGAACGCTCATATAATGAGAGTCCACAATGTGCCAGAGGGAGAGCCAATATATGGATGTAACTATTGTTCGTGCATATTTAAAAAGCTTGGAAGTTTGAACGGCCATATGAAACGCATGCATGCCGATATAGACGAGGAAGGAACCACTGTTGCTGATGCTACTAGTGACACTCATCCGGCCGATATCATGGAATCCGACATACGTGCGACCGTGGACAGTGTTATAACACAGTTGGCGTCTTTGGAAGCGAACacagaagaaattgaaaaatcgtCAAATAGCAAAGCGAATTTGTTGTCGGAAGGAACTATGAAAAAGGACATATTACAAGAAGCACTGAAAAATAGTGGTCTCCCTAGTAAAAATAAAACCCTGAACGAAGGTACGACGGAAACGAAAAAGCTTGGGGCGCGTACTAATTTTGTAACGTTATTGGATCGAGCGCCCGACGGTGGCACTAGaaaatatttaaccaTAAAACAGCGATGCGTAGGGAACATAAGGTGGTACGCGTGTACCTTTTGTCATAAGGAGTTTAAAAAGTCGTCAGATTTGATACGTCATCTTCGTGTGCACACGCAGGAGAAACCTTTCAAGGTATGCGATTGTCAGGGAAAAAGATTAATTTCTTCTATATGCCTTCCTGTTGTAAAGGAATTGACACTTTTTCTACACTTTCAGTGCACGCATTGTTATCGTTCGTTCGCTTTGAAGTCTACCATGATCGCACACGAACGAACTCATTCTGGTACGAAAAGATATGCTTGCGATTCTTGTGATAAAACATTTGCGTGTCACGGAAGTTTAGTTGGCCATACCAGATTGCATGGAAAATCTAAAAAGaattgtaataaaacaatTGTCGACGATGATAAGAACAGTGGTGCGCACACCAGAGAAAGTATCAGCGGTGTCTGTCAGTCGTCTGTCAATCAGTCGAAAGTTCAAGCTAAGAATAAGTCAAAGTTATCACCCGAAGCGGAGAGCCTAGCACAGCAAGTAGTGTTACAAGAACCCTTGGTAATCAGTGACACGGGGAATAAAATTTGCGTCGCGCAAGTAGCATCAAAGGAAAAACGTGCTTACGATGCGTCTACCGATCCAGCTAGACCGCACAAATGTTTGGTCTGCCAAGCGGCATTCAGAAAAATCAGTCACTTGAAGCAACATCACCGTCGGCACACCGGTGAACGTCCTTACGAATGCACCAAATGCGACAGGAGATTCACATCGAACAGCGTGTTAAAATCACATTTACACACGCACGAAGATTGGAGACCGTACGGTTGTCCCATATGCGATGCGAAATTTTCTACGCAAAGCAGCATGAAAAGGCATTTAGTTACTCACAGTAACAAAAGACCATTCATGTGTCCGTACTGTCACAAGACTTTCAAGACTTACGTCAATTGTCGGAAGCACATGAAAATCCATAAACACGAATTGGCACAACGGCAATTGGAGCAACAGAAACTTCAAATGCAGGAACAATCGACGGAGCAGATTTTTCGAGAAGATTCCAAAGAAATGAGAGCTCTCGAATCGAGCTGTTCGCCCTCTGTTTCGAACGCTACCAGTACAAATGTCGTCACCACCGTCGCTGCCACTTCTGCTATCATTACAACGGCCGTTTCTACGTTTTCCGACAATCTTACGTCGTTTTCTCGTCTTGGCGCGGTTGAAATATCGTTTCAGCCACAACTCGGTACCGATTTTTCACAAACTTTCCCGGAGCAGGAGAAGACGAGACCAGTTTTATCAGGAAATTGCGACGCTTCGACGTTTATTAATCACAACATATCGGAAACGGTAATGGCGAATCTTGAAAATACACAAATGTTACACGCTGATGAAACTGGTTCGGTTACATTGCCCCCCGTTTATTCCGGTGATCAAGCACTTACACCGgAGAGTATACGAGAAATAGAGGAAACATTGAACCAGCAGTTTTTTAACATCGGAATGAACATTAATCTTGAAAATAGTCATTCGAGACATTCAAACAACGCGAACCCGAATGATTTTGAAGGTGCAAAAGGCATAGAGGAAGAGCAACAAACGGTGCTGAACGTTATGTACGAAAACACTGACAATGATAATACCagtaacaataacaataatgataaaaaagaCGAAGGGAATGACAGCAACGTAGAACCATCCGAAGAGCATGTATTTTCATCGCAATTGGATTCATTCGAGATGGATCATATTGCGTTGCAATCGGACACTGAAATTGATATCGGATTGGTTGCAAGCGATTCAACGAGTATGGTAAGTATACTCCCTAGAACTGCGAAAGAACATCGGCTGTCTACTTCCGTTACAACGTCCGAGGATGCCCAGGACAGAGATGATTCGGGAAAAACTAGTATTCAAACGGTAGTGTTCATTTCGCAAGAAAATCTTTCGAGAAAGGAAGATGCAACGACGGAATTGGAAGGAGTGAACGAAGATGATATTCGAAAACAATGCGTAATGAGTCCGATGCTATTGACAGAAGGGTTCGGAGGATCGGTACAACAAGAAACGATAAAGAATCAATCAGAAGTGAACGCGATGTCTTCCTGTACGAATAAAATATCACACGGTGAATCTTTGTTACAATGCCATATGTGTAGTCAACAAGGATTTACGGCAATCGGATTAAAGGAACATTTAAAGACTCATCGTGGAACAAAGGAATATCAATGTACGGAGTGCTCTTCAAGATTTTGCACAAACGGTGGACTGAACAGACATTCGAAGATACACGTTGTTAAGCAATCATGGAAGTGTTCGTCTTGTGAGAAATATTTCAGTAGCAGAACGCAGTTGCGATCGCATAGCAAAATTCATGAAATCTCGATTTGGAACGCAATGTCTACGGGAACAGAGAACTCGCAGATTGTCACAGAGACTTCGGTTTCGTCAGATTTACAACCAGTTACGAATAACGGCGACCCGTGTTTAAACGATATCGCGATAGATCCAGACTCAGCTGTCTCTGAAAAAGTTCTGTTGGACACAATGGCGGAAAAGGCAGTGATGGATCAAATAGAAACTGTTTCAGGGGAGAGAAGGGAACGAAAAGAATACACGAATAAGTGTAAGTCTTGTCCGAAAACTTTTCGCAAGCCCAGTGATCTTATAAGGCACGTGCGTACACATACAGGAGAACGACCTTACAAGTGCGATTTCTGCAGCAAAAGCTTTGCCGTGAAATGTACTTTGGATTCGCATACGAAAGTTCATACCGGTAAGAAGACGTTCCGATGCCATGTTTGTAACAGTATGTTTGCAACCAAGGGCAGTCTAAAGGTTCACATGCGGTTACATACAGGTTCGAAGCCATTCAAATGTCCTGTATGCGACTCGAGATTTCGGACTTCGGGCCACAGAAAAGTACATTTATTGAAACACGCGCGGGAACATAAGGAGAGTCCAAAGAGGAAACAGAAACATCTGAAAGTTGCTGCCATAGCAGAAGTAGCGGCTGATTTAGAAAAACTTGGTGGAAATATAGAGAAAACGAGTAGCTTCGAATTGGatcaacagcagcaacaaTTGCCGCAGACAAAGGATTATCCTCACTTGGAAACAATTAGCGTCGAGACAGCTGCAACCTGTTTAACTGATCAAATCAACTTTGATACCGATACCGATACCGATGCGGCTATCGTATCGAACAATAATCCAACAATGGCAGCGAACGAAGGAAATCAGCAGTTGGTTACTAATctacattttcttttaacgAACGGACTGGTGACTATTCAAACCGAGGAATCGTTATTGTCGCAATCGACGTCGGTTAATAACGTGTCCTACAATCGTTCGACTATGACGTCCGATTCCGTGTGTATACCGACCCTCTGTATTTCATCCGGTATCAGCAACAACGATCATGCCAAGGAAGATATTCATACAGGGCAAATGATGAAAGCACAATTACCGtcatcatcgtcgtcgtcgtcgtcgcatCAAAAGAAATCTAACAACTGTCTGTTAACGGTTGCAACTTCTACGGTGCAAATGGAGCAACCATTGTCGAAAGTGTTTGCTGATAAATCTTTATCGACAACAACTAAAACGTTAACCAAAGGAAACTCGGCCAGAAAAGAGTGTGACATTTGTGGAAAAACATTTACGAAGCCTTATCAGGTTGAAAGGCATAAAAGGATTCATACGGGTGATCGACCGTACAAGTGCGATTTGTGTACAAAATCATTCGCTCAAAAATCTACTTTACAAATGCATCAGAAACATCACACGGGGGATCGTCCGTACGCCTGTCCGTACTGCGAATATTCTTTTACACAAAAAGGCAACTTGCGAACACACGTGAGACGGGTACATCAGTTGGATACGATCAATGCGAAGAAACTGAAGCGCGGCCGTCAATATTTTCTACCTAAATCAATTCAAGACAGCGTACTTGAAACAAAGACTTTGAATTTAGATGACATACCGTTCGTTGAATTCCTTAAATAG
Protein Sequence: MLTRHNIITESPHVEAIPINLVTTEDGRTLLAVTEHKDGMMEIVATPVTLIGQNGSPTSLVDVKNFNENFILHSPIFQLNIEDIVDGTDLQQPTENVEPGTATNDRLKSQMSMEAKCKTETSWEYRSPLQNDLTTINKQDESSVQKSVNDGVKRSSPGRPKKTATVSLQGTECLRCDICHQEFVKRTLYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDAFSTKAQLDAHLKLHGEKWATEEARKCKLCNKQFSQPALYRLHIREHYRLQTKVAKQTKKGTKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCSRAFTQKSSLQIHTWQHNGIRPHACELCNAKFSQKGNLNAHIMRVHNVPEGEPIYGCNYCSCIFKKLGSLNGHMKRMHADIDEEGTTVADATSDTHPADIMESDIRATVDSVITQLASLEANTEEIEKSSNSKANLLSEGTMKKDILQEALKNSGLPSKNKTLNEGTTETKKLGARTNFVTLLDRAPDGGTRKYLTIKQRCVGNIRWYACTFCHKEFKKSSDLIRHLRVHTQEKPFKVCDCQGKRLISSICLPVVKELTLFLHFQCTHCYRSFALKSTMIAHERTHSGTKRYACDSCDKTFACHGSLVGHTRLHGKSKKNCNKTIVDDDKNSGAHTRESISGVCQSSVNQSKVQAKNKSKLSPEAESLAQQVVLQEPLVISDTGNKICVAQVASKEKRAYDASTDPARPHKCLVCQAAFRKISHLKQHHRRHTGERPYECTKCDRRFTSNSVLKSHLHTHEDWRPYGCPICDAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKLQMQEQSTEQIFREDSKEMRALESSCSPSVSNATSTNVVTTVAATSAIITTAVSTFSDNLTSFSRLGAVEISFQPQLGTDFSQTFPEQEKTRPVLSGNCDASTFINHNISETVMANLENTQMLHADETGSVTLPPVYSGDQALTPESIREIEETLNQQFFNIGMNINLENSHSRHSNNANPNDFEGAKGIEEEQQTVLNVMYENTDNDNTSNNNNNDKKDEGNDSNVEPSEEHVFSSQLDSFEMDHIALQSDTEIDIGLVASDSTSMVSILPRTAKEHRLSTSVTTSEDAQDRDDSGKTSIQTVVFISQENLSRKEDATTELEGVNEDDIRKQCVMSPMLLTEGFGGSVQQETIKNQSEVNAMSSCTNKISHGESLLQCHMCSQQGFTAIGLKEHLKTHRGTKEYQCTECSSRFCTNGGLNRHSKIHVVKQSWKCSSCEKYFSSRTQLRSHSKIHEISIWNAMSTGTENSQIVTETSVSSDLQPVTNNGDPCLNDIAIDPDSAVSEKVLLDTMAEKAVMDQIETVSGERRERKEYTNKCKSCPKTFRKPSDLIRHVRTHTGERPYKCDFCSKSFAVKCTLDSHTKVHTGKKTFRCHVCNSMFATKGSLKVHMRLHTGSKPFKCPVCDSRFRTSGHRKVHLLKHAREHKESPKRKQKHLKVAAIAEVAADLEKLGGNIEKTSSFELDQQQQQLPQTKDYPHLETISVETAATCLTDQINFDTDTDTDAAIVSNNNPTMAANEGNQQLVTNLHFLLTNGLVTIQTEESLLSQSTSVNNVSYNRSTMTSDSVCIPTLCISSGISNNDHAKEDIHTGQMMKAQLPSSSSSSSSHQKKSNNCLLTVATSTVQMEQPLSKVFADKSLSTTTKTLTKGNSARKECDICGKTFTKPYQVERHKRIHTGDRPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYACPYCEYSFTQKGNLRTHVRRVHQLDTINAKKLKRGRQYFLPKSIQDSVLETKTLNLDDIPFVEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01123193;
90% Identity: iTF_01123193;
80% Identity: -