Basic Information

Insect: Oryzaephilus surinamensis
Gene Symbol: topi
Assembly: GCA_004796505.1
Location: SSSI01007534.1:31624-33963[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0022 0.21 12.2 2.5 2 21 103 122 102 123 0.94

2 14 7.8e-07 7.4e-05 23.0 0.7 1 23 148 170 148 170 0.96

3 14 0.0065 0.63 10.7 2.0 3 23 178 198 177 198 0.95

4 14 0.42 40 5.0 0.1 2 13 217 228 216 232 0.85

5 14 1.4e-05 0.0013 19.1 0.5 2 23 274 295 273 295 0.97

6 14 0.58 55 4.6 0.1 1 12 301 312 301 322 0.83

7 14 0.066 6.3 7.5 3.3 2 22 338 358 337 361 0.88

8 14 1.1 1e+02 3.7 0.1 1 23 489 512 489 512 0.93

9 14 0.0097 0.93 10.1 0.2 1 23 516 538 516 538 0.96

10 14 2.4e-06 0.00023 21.5 1.6 1 23 544 566 544 566 0.98

11 14 0.015 1.4 9.6 0.2 1 23 572 597 572 597 0.96

12 14 0.092 8.8 7.1 3.3 1 23 603 625 603 625 0.86

13 14 3.3e-05 0.0032 17.9 0.5 3 23 633 653 631 653 0.97

14 14 2.6e-06 0.00025 21.4 1.2 1 23 659 682 659 682 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0022	0.21	12.2	2.5	2	21	103	122	102	123	0.94
2	14	7.8e-07	7.4e-05	23.0	0.7	1	23	148	170	148	170	0.96
3	14	0.0065	0.63	10.7	2.0	3	23	178	198	177	198	0.95
4	14	0.42	40	5.0	0.1	2	13	217	228	216	232	0.85
5	14	1.4e-05	0.0013	19.1	0.5	2	23	274	295	273	295	0.97
6	14	0.58	55	4.6	0.1	1	12	301	312	301	322	0.83
7	14	0.066	6.3	7.5	3.3	2	22	338	358	337	361	0.88
8	14	1.1	1e+02	3.7	0.1	1	23	489	512	489	512	0.93
9	14	0.0097	0.93	10.1	0.2	1	23	516	538	516	538	0.96
10	14	2.4e-06	0.00023	21.5	1.6	1	23	544	566	544	566	0.98
11	14	0.015	1.4	9.6	0.2	1	23	572	597	572	597	0.96
12	14	0.092	8.8	7.1	3.3	1	23	603	625	603	625	0.86
13	14	3.3e-05	0.0032	17.9	0.5	3	23	633	653	631	653	0.97
14	14	2.6e-06	0.00025	21.4	1.2	1	23	659	682	659	682	0.98

Sequence Information

Coding Sequence: ATGTGCAGTAAATTCATGgaacataatattatttctctatataaaattactgaaaatggagaattaatttcaacaatCAAATATGAGATTGACTTCCAAACAAAAGAATTGATTTCGAAAACTTCTATTAGCGAAAATACATTACCAGAAACATTCTTGAAGTACGatccaaataaattaaatttaccacGAACAGcaattgtagaaaataaatgtaaatactaTCAATATCAAGAAGTTTATGGTAATGGTGATTCAAATGAGAAAAAACCAATTATTTCTATGTTAAACATACCTACAATGATGCGATGCCAGAATTGCGAGACAAATTTTCCCACAAAGTACCAATATCAGCGTCACCAATGTGAATTTAATGCCGATAAAGTGATTTTGAAGGCAGATGCTGATTATAAAAGTATGGAAAATGGTGTACGAATAAAATACGATTGCAATACATGTGGAAAACAGTTTgttagtaaaaataatttgaatcgTCATCAGGCGGGTCATGAAAATTCACAATCGAACATTTGTGAACACTGTAATAAGCAATTTGTGAGTGAAAATCGTTTACGTATTCACAAAGAGAATCATTGTAAAAAAGCCGGAGATTTGTCCAAGTTTTATCGAAGTGATGTGACTGTATGGAAGTGCATGAAATGCCATGAGGTGTTTTCATCAATAAGTTTGGCCAATTTTCATGTGGAATCATGTGCGGAGGAAGTTATTACATTGGATGGAGACTCAGTTGAACAAACTTCACAAGATTCTACAATTGAGAATCAGAATGTAAAGAAAATTCTTACGGAAATTTTACTACAATGTGAATTCTGTAATCGTACATATGCTGATAAAAATCTATTAGTGGCCCATATGAAAAAGCATACAACAGCTAAGAACTATGAATGCGTTAATTGTAATGAAACATTCGATTCATTTGCAGTGGCATCACAACATTGGATGAGAAAATGTtcagaattttcaaatttattctgTTTACCAAAATTAACGTATTGCGAAAGATGTGATCGTACATTTAAATCGCACGAAGTTTTGTATACACACAAAATCAAAAAGAAACATTATAAGCCGAAAAAATGTGCCGAACCAACAAATGAAAATCATcaaaaatcaaatgaaattaaacgTACTTTTGATGAATTGATTCAAGATGTTTTAAAAACGTTAAGTTTGCCATTAAATCCgaacaataataaacatgaaaatgTAGGTGAAACCGCTGAAAAAGTCGATCATGAAGAAATCATTGAAAATGATGATAAACAAGATAAAGAAGAAGAGAATAAGGAGAATTGCAATGATGATATTGAAATAAAGGCCCAACAAGATATGGAGGACAAATCTACTGGTAAAAAGAAGAGAGGTCGTAAAAGGCGTTTAATAAAACCATCAACAGCAAATAAATCAAAGCGTATTTGTACAACATTGGAAAATGGCTATAAATATCAATGTGAAagatgtataaaaatatttgattcaaTTGTTGAACTGGATGGCCATCGAGAAAAAGAGCATGctgttatatttaattgtgaaGAATGTGGCcagGTTCTGCACAGTGCAAGAGCCCTTTTGATACATAGCAGGGCGCACAAGAACTTAAAACCGTACGTTTGCGATGCTTGTGGCCGCAGTTATTCGCAAACGTCTCATTTATGGCAGCACATGAGATTCCATCAAGGAATCAAACCATTTGCATGTCCACATGAGGGATGTGAAGCGCGATACACGATTAGACCGGATTTAAAGGATCATATAAGAAAAGTGCATACAAGAGAACGTCCATTTAAATGCAATGtgtgtaataaatgttttctaaCTGGGTCAGTTTATTATCAACATCGATTGATTCATTCGAATGATCGACGATATGGTTGcgatgtGTGTCAAAAACGATTTTTCCGAGCCGATGCGTTGAATAATCATAAAAGAATACATACGGATGAAAGACCATATCCTTGTAATAGATGTGGACGAGAATTTCGACAAAAAGGCGATCGAAATAAACATATACGTACTCAACATATGGAAGTTcctaataatgtttaa
Protein Sequence: MCSKFMEHNIISLYKITENGELISTIKYEIDFQTKELISKTSISENTLPETFLKYDPNKLNLPRTAIVENKCKYYQYQEVYGNGDSNEKKPIISMLNIPTMMRCQNCETNFPTKYQYQRHQCEFNADKVILKADADYKSMENGVRIKYDCNTCGKQFVSKNNLNRHQAGHENSQSNICEHCNKQFVSENRLRIHKENHCKKAGDLSKFYRSDVTVWKCMKCHEVFSSISLANFHVESCAEEVITLDGDSVEQTSQDSTIENQNVKKILTEILLQCEFCNRTYADKNLLVAHMKKHTTAKNYECVNCNETFDSFAVASQHWMRKCSEFSNLFCLPKLTYCERCDRTFKSHEVLYTHKIKKKHYKPKKCAEPTNENHQKSNEIKRTFDELIQDVLKTLSLPLNPNNNKHENVGETAEKVDHEEIIENDDKQDKEEENKENCNDDIEIKAQQDMEDKSTGKKKRGRKRRLIKPSTANKSKRICTTLENGYKYQCERCIKIFDSIVELDGHREKEHAVIFNCEECGQVLHSARALLIHSRAHKNLKPYVCDACGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCNKCFLTGSVYYQHRLIHSNDRRYGCDVCQKRFFRADALNNHKRIHTDERPYPCNRCGREFRQKGDRNKHIRTQHMEVPNNV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -