Basic Information

Gene Symbol
ZNF236
Assembly
GCA_004796505.1
Location
SSSI01007649.1:36753-42136[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.12 11 6.7 1.6 1 23 129 151 129 151 0.96
2 24 0.00028 0.027 15.0 0.4 1 23 157 179 157 179 0.98
3 24 0.0012 0.12 12.9 1.5 2 23 185 206 185 206 0.97
4 24 0.0015 0.14 12.7 0.4 1 23 212 234 212 234 0.98
5 24 0.003 0.28 11.8 0.1 2 23 246 267 245 267 0.95
6 24 0.00018 0.018 15.6 4.8 1 23 296 318 296 318 0.96
7 24 2.1e-06 0.0002 21.7 0.6 1 23 324 346 324 346 0.98
8 24 6.5e-05 0.0062 17.0 0.3 1 23 352 375 352 375 0.96
9 24 0.058 5.5 7.7 2.1 1 23 385 408 385 408 0.96
10 24 6.1e-07 5.8e-05 23.4 3.1 1 23 512 534 512 534 0.98
11 24 1.3e-07 1.2e-05 25.5 0.7 1 23 540 562 540 562 0.98
12 24 0.0019 0.18 12.3 2.9 2 23 569 591 568 591 0.96
13 24 2.1 2e+02 2.8 2.5 1 23 599 622 599 622 0.91
14 24 8.6e-07 8.2e-05 22.9 0.4 1 23 661 683 661 683 0.98
15 24 0.00045 0.043 14.3 2.7 1 23 689 711 689 711 0.98
16 24 2.6e-05 0.0025 18.2 1.1 1 23 717 739 717 739 0.96
17 24 0.00082 0.078 13.5 3.8 1 23 745 768 745 768 0.97
18 24 3.7e-05 0.0035 17.8 1.5 5 23 1024 1042 1021 1042 0.93
19 24 7.6e-07 7.3e-05 23.1 1.3 1 23 1048 1070 1048 1070 0.98
20 24 5.1e-05 0.0048 17.3 1.0 1 23 1078 1100 1078 1100 0.98
21 24 0.072 6.9 7.4 3.4 3 23 1108 1129 1106 1129 0.93
22 24 0.00016 0.015 15.8 2.8 2 23 1277 1298 1276 1298 0.97
23 24 4e-05 0.0038 17.6 0.4 1 23 1302 1324 1302 1324 0.97
24 24 0.01 1 10.0 0.4 1 23 1330 1353 1330 1353 0.97

Sequence Information

Coding Sequence
ATGTTAGCATTAAATGATGTGATGAATAGTGAACAAAATATACcgaaaattgttacaatatcAATACCGTTAAATGTAACAGGAGCATCGACTGCTACATCCTGTGTTAAAAAGGATAATAatcagaaattattaattaataatgattttaaaatattacagaACATTGTTGTTAAAACAATTACTCAAGATGGTGCAGTGTGCATACAGAATGTAAATCAAGTTAATAAGCCCGAAATAATcgaaaaaattccaaaaattgCAGAACAAGacagcaCCGAAGCTGGTACTTCCAATAGCCCACCAAAGaacaaaatctatttaaaaccTATAGCCAGAAGCAAAAAATCTGAAAACTCACCcaaatcaacaacaaatcaAACCTTTCGTTGTATAAAATGCACTGAACAGTTTTCAACAATTCTTGAATATCGGAAACATATGTTAAATCATCgcaattcaaaaaaatatcaatgttCAAAATGTTCAGCAAGCTATAACAATGAACGGAATATGGAAATCCATATGGCTATGCATGCAGATGGCAAACCAACGTGTCCATTATGCCAATTAACGTTTCATCGTTTGGCAAGTTTAAAATCGCATTTAATGTTGCATCAAGTTGAAGAAATTTTTACATGTGAAGAATGTAAATCTGAATATGATGATGAGGAGAACTTATTGAAACATTATGAGACACATGTGATGGAAAAATTCAACGAAAATAAACCGATAGAGTGTCCGTATTGTAAAGTCGTTTACGAAGACACAAATCAATTAAAAGAACACATTTCTTTTCatatgattttgaaaaaaatgatgtTGAAGAGCAGAGGGCCAAAGAAAAAGCCATCACAgcaagttaaaaataaaaaattggggGCACACGCTTGTGATAAATGCAATAAACGTTTTATGAAGGCTTGTTTATTGGAACGACATATACGAACACATACTGGCGAGAAACCATTCGTTTGTACCATTTGTAATACTGCTTTCACCCAAAAAGGGACACTACAAATACACTTAAACAAACATACTGGCTTAAAACCGTTCGAATGTACTTTATGTCCGGCGAAATTCAATCAAAAGGGCAACTTACGTGTACATGTTGAAAAAACACACACAGCTGACGagaaaaatgagaaaatcTATAAATGTACATCGTgtacatgtatttttaaaacagttgCATCGTTAAATGGTCACGTAACGAAATTACATACGAAATTATCGAATGAAAACGATTCAGTTCAAATGGTTATgaagaaattaaaagaattacaaCAGCAATTAAATCAAACTAGTAATAATACTAAAGAGAAACGACCTGAAGGTGATTCGTTGATGCAAGTTATGAGAAAATTGAAAgaattacaaaacaaacaaacgaATAACGAGAAAAAGAGTCAATTGAATAATGAAAACGATTTAGGCGTTACTTATGTGCGTTTAGCTGAACCGAATCAAATGCAAAACGGTATTGTTCGACGTTATTTAGCGAAACGTGTTATTGTTGATGGCGTTAGATGGTATTGTTGTAATTATTGTCCGAAACAGTTTAAAAAACCATCAGATTTGATGCgacatttaagaatacatacaaGAGAGAAACCTTTTGagTGTGAAGAATGCGGTCAATCGTTTACATTAAAATCAACGTTAAAAGTTCATATGAATACACATAAGGAAAAAcaagtaataaaatgtttaaaatgtgataaaatatttaaatcaaatttgttgTTACATTATCACATGTTACGGAAACATGAACGCAAATATTCTCCTACATATGAATGTGTAAAATGTAAGAAATTGTGTAAAACAACAAAAGCCGCCAATCAACATTTAGATGAAAAACATCCACACGCTAATTTTGAAGATTGCATGAAATTTGTGTTGAAACAACCGATATTTCGTACAGCATACGGTAATTTGGTTATAAGAAGAAAGCAAGATAATGTCAATGAaaagccattttcgtgtaatatTTGTGGTGCATCGTTTGCACaacgtttaaatttaaaaacgcacatgaaaattcatttgagcgacagaaattttaaatgcaatttatgtCCAAAGACTTTTTTGTCATCTTACAAGCTCAaagaacatttaaaatatcataatAACATTCGCAACTTTGAATGTACAGTTTGTTCGAAACGATTTGTTACAAATACGTTATTAAAACGTCATTCATTGATACATAGTAATGAAAAGCCTTATATGTGCCCATATTGTtcgaaaacatttaaaacattaacattaaCACATCAGCATTTGAAAAAAGCACACCAGGGAGAAATTACGGATGcgAATTTGCACGGAATTGTTGAGGAAGAAGATAATAATGAAACTGATGAAGAAATTGAATATCATTACACACCAGTGCCAGACAATATTCAAATACAgTTAAATCCTGGTGAGAATCTTAATTTACCATtaaatacaatggaacaaaatttacaaacagATTTAACAACGTCTGCCGACTTAaatcaacaaacaatttatataaatagcGACAATGTTGGTTTAGATAACGAAAACTTAcaacaatgtttaattaatttgttaaacaacgattatcaacaacaaaatacaacaaactTGCAAGAAAATACAGTAGATTATCAGAATGGAATGGATTTAGTTGAtatcaacaatataaatatgatattAAACCAAAATAATATTAGTTGGGATGATTTGAGtgaattattaacaaatgttaATGACAATACTGGTAATTTGAATGAGAATTTAACGGAATTACCGCAACAACAGCCGCAGGAACAACAAGATAATGAACAAGAAAGCTTGTACGccaatacatttataatttgtttaagttGTAATAATCAATATGATACTGttgaacattttaaacaacacAATTGTACGGAAAATGAAAGCAACGAAAcggaaaatggaaataataagaaaaaaacaacaaaacaatttgaatGCATATTTTGtgatgaattaattaatggtaggaaaatgtatgtaaaacatATGGCTATACATGCGAAAAATGGACAGTCAAATACTTGTATTTTTTGTgagaaacaatttaaaaagcCTTCGGATTTgaaacgACATATTAGGacacatactggtgaaaaaccattCAATTGTGAAAAATGTGATAAATCGTTTGCATTAAAATCGACATTAATATCGCATATGAAAACACATGATCCAAATGtaccaaaaaaattcaaatgcgATGTTTGTAATTCGTATTTTACTGTTAGAAGTAGCTTAAAGGTCCACATGTTAATGCACACAGATAAAAAACCGTATGGTTGCGATTATTGTACGGAAACATTTCGCACAGCTGCACATAAACGTTCTCACGAACATTCACAACACCTGAAAAAGGATCAAGAAGTTTTAAAAGAAGCGAAAAAGGATGTTAGAATAAAGAATTTGTTAGAATCAGTTGTTTCTGAGATTGTAAATAACCAATCAAATGATTTTAGTGATAATATTCAACCGGATAATCAGGAAATCATTTTAcaCGATAATCCGTTAAAtgtgttaaatataaatgcagAAGGTTTGGATTTAAATGATACAATACAAATCGATCCATTAACTTTGTTGCAATTTCAACAAGCTTCTATTAATTTGCCAGAATCATCGAGTATATTTATAGACACGAATTGTGGCcaaaataatgaacaatttcTACAAATTGATGATGGTGCCTTGTtgaataattgtatacaacaGCCACAAACGTTTGAAAATGTTGTACAACCGCCAGAAGTTATGCAATTcaatgaaaaaacaaataaagaaCGTAATTTACAGTGTGATATCTGCAAAAAATGTTATGCTTCTAAGGATGTGTTACGTAAACATAAGAAAATACATATGAAAAAGTATCCGTGTACAATATGTGATAAAAGTTTTGATAAAGATGTGGATTTTAATAAGCATATGGATTTACATGCCGGTTTGAGGCCGTTTAATTGTGCTTATTGTGCGAATAGTTTTGGGGAAGAGAGTAGTTTGAAAACGCATTTGAAGAGAATACATCCGGAAATTGAAACGACTAcagatgatttttttttaaagtttggagatgattttatgtaa
Protein Sequence
MLALNDVMNSEQNIPKIVTISIPLNVTGASTATSCVKKDNNQKLLINNDFKILQNIVVKTITQDGAVCIQNVNQVNKPEIIEKIPKIAEQDSTEAGTSNSPPKNKIYLKPIARSKKSENSPKSTTNQTFRCIKCTEQFSTILEYRKHMLNHRNSKKYQCSKCSASYNNERNMEIHMAMHADGKPTCPLCQLTFHRLASLKSHLMLHQVEEIFTCEECKSEYDDEENLLKHYETHVMEKFNENKPIECPYCKVVYEDTNQLKEHISFHMILKKMMLKSRGPKKKPSQQVKNKKLGAHACDKCNKRFMKACLLERHIRTHTGEKPFVCTICNTAFTQKGTLQIHLNKHTGLKPFECTLCPAKFNQKGNLRVHVEKTHTADEKNEKIYKCTSCTCIFKTVASLNGHVTKLHTKLSNENDSVQMVMKKLKELQQQLNQTSNNTKEKRPEGDSLMQVMRKLKELQNKQTNNEKKSQLNNENDLGVTYVRLAEPNQMQNGIVRRYLAKRVIVDGVRWYCCNYCPKQFKKPSDLMRHLRIHTREKPFECEECGQSFTLKSTLKVHMNTHKEKQVIKCLKCDKIFKSNLLLHYHMLRKHERKYSPTYECVKCKKLCKTTKAANQHLDEKHPHANFEDCMKFVLKQPIFRTAYGNLVIRRKQDNVNEKPFSCNICGASFAQRLNLKTHMKIHLSDRNFKCNLCPKTFLSSYKLKEHLKYHNNIRNFECTVCSKRFVTNTLLKRHSLIHSNEKPYMCPYCSKTFKTLTLTHQHLKKAHQGEITDANLHGIVEEEDNNETDEEIEYHYTPVPDNIQIQLNPGENLNLPLNTMEQNLQTDLTTSADLNQQTIYINSDNVGLDNENLQQCLINLLNNDYQQQNTTNLQENTVDYQNGMDLVDINNINMILNQNNISWDDLSELLTNVNDNTGNLNENLTELPQQQPQEQQDNEQESLYANTFIICLSCNNQYDTVEHFKQHNCTENESNETENGNNKKKTTKQFECIFCDELINGRKMYVKHMAIHAKNGQSNTCIFCEKQFKKPSDLKRHIRTHTGEKPFNCEKCDKSFALKSTLISHMKTHDPNVPKKFKCDVCNSYFTVRSSLKVHMLMHTDKKPYGCDYCTETFRTAAHKRSHEHSQHLKKDQEVLKEAKKDVRIKNLLESVVSEIVNNQSNDFSDNIQPDNQEIILHDNPLNVLNINAEGLDLNDTIQIDPLTLLQFQQASINLPESSSIFIDTNCGQNNEQFLQIDDGALLNNCIQQPQTFENVVQPPEVMQFNEKTNKERNLQCDICKKCYASKDVLRKHKKIHMKKYPCTICDKSFDKDVDFNKHMDLHAGLRPFNCAYCANSFGEESSLKTHLKRIHPEIETTTDDFFLKFGDDFM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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