Oinc027036.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Orthosia incerta
Gene Symbol
ZEB2
Assembly
GCA_948252205.1
Location
OX411769.1:2156464-2161140[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.022 3.1 9.7 2.2 1 23 216 239 216 239 0.96
2 15 0.0026 0.36 12.6 1.0 2 23 245 266 244 266 0.95
3 15 0.24 33 6.5 2.8 2 21 270 289 269 290 0.93
4 15 0.0066 0.9 11.4 1.2 2 23 332 354 331 354 0.95
5 15 6.8 9.3e+02 1.9 0.4 3 23 362 381 361 381 0.83
6 15 0.0025 0.34 12.7 0.5 1 23 387 409 387 409 0.98
7 15 0.012 1.6 10.6 2.6 1 23 415 438 415 438 0.97
8 15 0.0085 1.2 11.0 0.8 1 23 447 470 447 470 0.95
9 15 0.0094 1.3 10.9 8.6 1 23 480 502 480 502 0.98
10 15 5.5e-05 0.0075 17.9 0.2 1 23 694 716 694 716 0.97
11 15 0.00079 0.11 14.3 0.3 2 23 722 744 722 744 0.95
12 15 0.015 2 10.3 4.7 1 23 777 800 777 800 0.96
13 15 7e-06 0.00097 20.7 2.3 1 23 806 828 806 828 0.97
14 15 0.028 3.8 9.4 1.4 6 23 839 856 837 856 0.96
15 15 0.12 16 7.4 1.5 6 23 871 888 869 888 0.96

Sequence Information

Coding Sequence
ATGAGCCGGCAAGTGGATATAAAGGCCTTAGTGTCCCATATAGTGCGTGGAGACGGGTCAGAAAGATGCCGAATATGTATGGGCGATACCACAGAAGGACAAGTTCATTTAGAAGACACGGTTATGATGGATGGGGACAAGCCTGTTACGCTTGCTGAATTGCTAGAAGTCATCACAGGAGTCGAGGTGCAGCTGGATGATGACCTGCCTCTAGGCCTGTGCTCCATATGCTCAGTGTCAGCACTCCAAGCAGCAGACTTCAGGACCCAGTGCCGAAGAGCGGCCATACAGTGGGAGACCACACTGGAACTGCTGAACAGCATACCAGAACAAAAAGCCCATAACAACCGAATCATTGCAATAGTCACTGAAAATACTATCTGTATTACTACTCATGAAAAAGAGGAACAAAAGCCAGTTTTCACAGAATCACCGAAGTTACCAAAGCAGAAAAGTAGGTGTGAGAATGTTAAAAGTACTAAATGTCAGTGCCCATGCTGTGGTAAGCGGTTTTTGTATGCCCAACATCTGTGCCAGCATTTGAAAGAGTCGTCCAACAACCAACATGCTTGCTACATTTGTGCTAAAATTATGACGAGGCAAGAGTTGATTACACACTTGATTGAAATGCATAACAGAGAGCCGTATGATTGTAAGAAATGTCCTGCTATGTTCCATACTTATATGCAGTATAAGGTGCATCTCTCAAAGGCCCATGCATCTGGAGCCTGTACTTGTGGGGAATGTGGCCGCAACTTCCAGAGCCAACAAGCGTATTATGCCCATCTTTCAGTCCATACCCCAAAAACATGTCCCGGTTGTGATGAATTGTTTAGAAACCAGAAATGCTACCACTACCATGTCAAACAGTGCTGTAACCTTGACAAAACTCGCTTAGACGTCCACAAGACTAAAAACAAAGCGACTATCACAGTCAAAAAGAAGAATAAAAGCATCAAAGTTGGTATGCGAGGAAGTGCAGATTCAGAATGTTACTGCGACTACTGCAAAAAGAAATTCGCTGGGAAGAAATTCGTTGCCGCACACATACAAATAGTACACATGAAGAATACTCATCGGCCTTGTGTATACTGCGGAAAATTACTCGCAGCAGCTCACATGACCACTCACGTCAAAAAACACGAATCAACTGAGTCTTTCCAATGTGGACATTGCGGTATCGTATTAAAAACGAAGTTAGGATACATTCAACACGTGCGCTTACACACTGGCGAGCGTCCTTACGCCTGTAAGTTCTGCGGGGAATCCTTCTCAGCGTCATCTAGACGGTCAGAACACATCAGAAAGTGCCATAGAGAGTCTGAAATAGTTTTGAATCATGCTTGCCAGTTGTGTCCAGCGAGGTTTCGATTGCCTTACAGACTCAAGAAGCATGTTAGCACGGTCCATGGTGGAGAGAAGGGGAAATTGCTCCAGTTTGAGTGTAATGACTGTCACCAGAAGTTTAGTAGCTGCAGGGGATTGCTGCATCATAGTCGGAAGCACCTTGCTGCTACGATCTTGAGTGATGATAATACTCCTAAGGTTTCGAGATTGAAGGAGGTCGAGCACTCAGCACCGCTGCCTCACACAATCTGCTTCGGATGTGATAAGGACCTAAAATCAATACTGCCTTTCATAAATCGTTGCAAGGAATCCGCAAAACATTGGAATCAAATCACCAACTTCTTATACATGTTCGTACCACCAAATAATGCTAAAAATCTTTACTTAGAAATCGGTAATGATATAAAAACTTACACAGACACATCAAGATGTCAAGTTAGTAAGATAACAACGAAGAAAGCGGCCCTAGAGGGCTTTAAATTGAGGATTCGTCGGCAAATGATATACAAAAGTCGGTCGGTGCAGACCGAAACAGTAGGTCATAGCGGTTCAGGAAAAACAGTTGTAGGAAAATCCAAAATGTCATGTCCTAATTGTGCCGCAACATTTCAATGCTTCTTCAAATTCAATATGCACTTACGTGCATCTCGTAAGAAAATCTGCAGATTCTGCTTTGAAATACTAGATTTTGACGCTTATGTAGAGCATTGTAAGGTTCACTATTTGACAGTATTCGCTTGCCCGATTTGCTCAGAAAGTTTCGAAAAAAAATCCGCTTTGTTATCGCATACACTCAAACATGTTAGAGGCCTTGAAGAATGCCTTGAGTGTCGTGAAACCTTCGCAGATGCTGCGCACTTGAGTAAGCATGTGAATATACAACACAAACCTATCGCCTGCGGATGCGGCAAGAGACTGCCAAACCGTCTTTGTTTCTTCCAACACAAGAAAATCTGCAACCAAAACGATACGATGTCTAAATTCATTTGTGATTACTGCAAAACAGAATACAAAAAGAAAAACTGTTTGAGGATGCACATTAAGTTAAGACATACTGTCGGATGGCTTTTCCAGTGCGACAAATGTGGAAAGAAATTCTCAAGCCGTGCGCATTTACTGGAACATGGAACTACTCACGATGGGGTCACTGATAGGCATGTTTGCTTCTGCGGTGCTAAGTATAGCTCAAGAAGGGGGTATGAAAGGCATATGAAAAAGCATCCGGATGTGGAAAAGCTTAAAGCTTCAAGGTATGTTTGCTTCTGCGGTGCTAAGTACAGTACAAGAAGGGGGTATGACAGGCATATGAAAAAGCATCCGGAAGTGGAAAAGCGCAATGCTTCAAAAGGAAAGATTAATTTAGAGACCTAG
Protein Sequence
MSRQVDIKALVSHIVRGDGSERCRICMGDTTEGQVHLEDTVMMDGDKPVTLAELLEVITGVEVQLDDDLPLGLCSICSVSALQAADFRTQCRRAAIQWETTLELLNSIPEQKAHNNRIIAIVTENTICITTHEKEEQKPVFTESPKLPKQKSRCENVKSTKCQCPCCGKRFLYAQHLCQHLKESSNNQHACYICAKIMTRQELITHLIEMHNREPYDCKKCPAMFHTYMQYKVHLSKAHASGACTCGECGRNFQSQQAYYAHLSVHTPKTCPGCDELFRNQKCYHYHVKQCCNLDKTRLDVHKTKNKATITVKKKNKSIKVGMRGSADSECYCDYCKKKFAGKKFVAAHIQIVHMKNTHRPCVYCGKLLAAAHMTTHVKKHESTESFQCGHCGIVLKTKLGYIQHVRLHTGERPYACKFCGESFSASSRRSEHIRKCHRESEIVLNHACQLCPARFRLPYRLKKHVSTVHGGEKGKLLQFECNDCHQKFSSCRGLLHHSRKHLAATILSDDNTPKVSRLKEVEHSAPLPHTICFGCDKDLKSILPFINRCKESAKHWNQITNFLYMFVPPNNAKNLYLEIGNDIKTYTDTSRCQVSKITTKKAALEGFKLRIRRQMIYKSRSVQTETVGHSGSGKTVVGKSKMSCPNCAATFQCFFKFNMHLRASRKKICRFCFEILDFDAYVEHCKVHYLTVFACPICSESFEKKSALLSHTLKHVRGLEECLECRETFADAAHLSKHVNIQHKPIACGCGKRLPNRLCFFQHKKICNQNDTMSKFICDYCKTEYKKKNCLRMHIKLRHTVGWLFQCDKCGKKFSSRAHLLEHGTTHDGVTDRHVCFCGAKYSSRRGYERHMKKHPDVEKLKASRYVCFCGAKYSTRRGYDRHMKKHPEVEKRNASKGKINLET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01231055;
90% Identity
iTF_01117738;
80% Identity
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