Basic Information

Insect: Orthosia gracilis
Gene Symbol: THAP3_2
Assembly: GCA_947562075.1
Location: OX387277.1:5648986-5676612[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.067 6.4 8.2 0.8 1 23 358 380 358 380 0.95

2 11 0.002 0.19 13.0 1.2 1 23 387 410 387 410 0.93

3 11 0.29 27 6.2 0.3 1 23 414 436 414 436 0.92

4 11 0.039 3.7 9.0 1.2 1 23 441 464 441 464 0.97

5 11 0.0005 0.047 14.9 0.7 1 23 468 491 468 491 0.97

6 11 4 3.8e+02 2.6 0.1 2 19 504 521 504 524 0.77

7 11 1.4 1.3e+02 4.1 0.2 3 23 581 602 579 602 0.94

8 11 0.0041 0.39 12.0 0.6 2 20 618 636 617 639 0.92

9 11 3.1e-05 0.0029 18.7 3.1 1 23 645 667 645 667 0.99

10 11 0.00024 0.023 15.9 2.8 1 23 674 696 674 696 0.98

11 11 4e-05 0.0038 18.4 0.7 1 23 702 725 702 725 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.067	6.4	8.2	0.8	1	23	358	380	358	380	0.95
2	11	0.002	0.19	13.0	1.2	1	23	387	410	387	410	0.93
3	11	0.29	27	6.2	0.3	1	23	414	436	414	436	0.92
4	11	0.039	3.7	9.0	1.2	1	23	441	464	441	464	0.97
5	11	0.0005	0.047	14.9	0.7	1	23	468	491	468	491	0.97
6	11	4	3.8e+02	2.6	0.1	2	19	504	521	504	524	0.77
7	11	1.4	1.3e+02	4.1	0.2	3	23	581	602	579	602	0.94
8	11	0.0041	0.39	12.0	0.6	2	20	618	636	617	639	0.92
9	11	3.1e-05	0.0029	18.7	3.1	1	23	645	667	645	667	0.99
10	11	0.00024	0.023	15.9	2.8	1	23	674	696	674	696	0.98
11	11	4e-05	0.0038	18.4	0.7	1	23	702	725	702	725	0.93

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTAAGAACTGTTCTAATGACACGAGAAGAAATAACAAAAGCCATGGGATCACATTTCATATGTTTCCAAAACCGCTGGATCTCCGGAATGCTTGGGTAGAAGCCCTGGGTGAACCGGACTGGGAACCCAAAGAGCGGAGTACCATATGCTCCGAACACTTTAGGAACGACGACTTTTATACGACTCAGCGCGGCTTAAGAAGGATCAAGTGTGGAGCTGTGCCAGTTGTCATGACTGAAGCGTTGGGAGATCTTGACGCCCCGGCAGCATTGAGGGTGTGCCGAATATGTCTTGCGATGGACACGAAAATGTATCACATACAAGAACACAAGCTGGACCAAATGTATGAGCACATCACTGGCTTAATGGCTAGACCAGAAGACCGTCTCCCGCAGCGCGTGTGTTGGGAATGCGCTGGGCGCCTATTAGCTGCTTGTCGATTTAGGAGTAAAGCGTTGCGGAGTGATGCTGTGTTACATGATACACTACGCTCTGACACTTATATTAAAATCCGGGACATTCGCTCAATAAACAGGAAACATCACAACCTAACATCAACTTTAGTACAACAAATAATTGAAAACGACGATTTCGACCTTCACGTCAAAGACTTAGCCATCAAGACTGAACAGATACCTGACCTGGATACAGCGGAAAACATACCAATAGACACGGAAGATATTGACGTCAAATCTTTAGCACCGGTCGATGAAGTAGGAATCAAGGATGAGAGCAGTAATGAAATATTCTTCGAGGAATATGATCATTTCGACGATGATGATGATAAAGCGTTGAGTGAAGTGTATGTAGAGAAGAAGGAAACGCCTAAGGTGAAGAAGAAACGGGAGAAGGGGGTCAAAAAGGTCAAAACCAAGAAGTCTGAAGATGAAGCTGATCCGGATCATTGTAGTGATAAGTACAAAAAAACAGACGTAAAACGCCGTCGAAACAACGAAGGTTTCGACGAAAACCTATTCACCATCACACCGCTAACGTACGACCAACAGATTGAAGAGATCTTGAAAAGACAAGAGAGTTACAATTACACCAGTGCGCCGTACAAGTGTACTATATGCTACCGAGGGTTCCAGATTAAAGATCGGTTCACTGCGCATGCTGTGAGGCATAGTGAGCAATGCGGTGCCTACGAGTGTTTTATCTGCAAAACTAGATTGAAGACGAGTCGTGCGCTGCGGAAGCACTTGACGGCACAACACACAGAACAATATACCTGTAAGGGATGTCCGTTTATGACTAGAAATAGGGGAGTAGCGAGAGAACATGAAAAATGGCACGCTGGGACTAAATACCAGTGTCCACACTGTGCTAGTACGTTTGATAAAATAACAACATATATGGGTCATATTCGTATAAAGCATGTCTCGGACTTCGTGTGTGAACTCTGCGGATATACTTTCGTTAGTAAGAAGGGCATCGAAGTACACAAGAAGAAGAAGCACCGGATGTATAAACAGGAGACAACATTAGAAGGGCCGTACTGTGAAATTTGTGATGTAAAGTTTATGTCAGAGGACGCCCACGACAGACATCTGAAGTTATCTTCAAGACACAGCAGTGATCATGACCCTAACCGAATCAGAAACGACTCTCAAAGCATGAACGCGGAACGTAGCGGCCGAGTGATGAGACGTATTGAGAGGAGACCAGTCATCCATCCGCGCTTACCCACCGATGTTGACCAGCAAGACCCCCAGGCTCCCGTGAACTGTGAACAGTGTGGCTTGCAACTTCGTGACTTGCGAGTGTATGCTCAGCACTTCAGAAGAGCCCATCCGGACAAGAACCGCACCAAGTACCCCGCGATGAAGACCCCCTGCATGTGCGAGCAGTGTGGCAAGATATTCCAGAGCATGGCCCTCCTAAAAGACCATATGTGGGTTCACACTGGGGAAAAACGTTTCAAATGTGATCGCTGCACGAAAAGTTTCACACAGAAGACGAACCTGGTGTTTCATATGCGGGTCCATAGCGCGACTCGACCGACCTACGAGTGTCCCTTATGTGGCAAACACTTCGCGTTCTTCAATAATCGGAGACGACATATGTTTATACACACCGGTCTAAAGCCGTTTAAGTGCGACACGTGCGGCAAGTCGTTCACCACGGCGGGTGAGCAGAGAGCTCACGTTGAGCACGTGCACCTCAAGAAGCCCTGGCCCAAGAGGGCGCGCCAGAGGAACCACGATTGGAAGTGCGACGAGCCTACTGTAGAGGACTGA
Protein Sequence: MRCSVKNCSNDTRRNNKSHGITFHMFPKPLDLRNAWVEALGEPDWEPKERSTICSEHFRNDDFYTTQRGLRRIKCGAVPVVMTEALGDLDAPAALRVCRICLAMDTKMYHIQEHKLDQMYEHITGLMARPEDRLPQRVCWECAGRLLAACRFRSKALRSDAVLHDTLRSDTYIKIRDIRSINRKHHNLTSTLVQQIIENDDFDLHVKDLAIKTEQIPDLDTAENIPIDTEDIDVKSLAPVDEVGIKDESSNEIFFEEYDHFDDDDDKALSEVYVEKKETPKVKKKREKGVKKVKTKKSEDEADPDHCSDKYKKTDVKRRRNNEGFDENLFTITPLTYDQQIEEILKRQESYNYTSAPYKCTICYRGFQIKDRFTAHAVRHSEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYTCKGCPFMTRNRGVAREHEKWHAGTKYQCPHCASTFDKITTYMGHIRIKHVSDFVCELCGYTFVSKKGIEVHKKKKHRMYKQETTLEGPYCEICDVKFMSEDAHDRHLKLSSRHSSDHDPNRIRNDSQSMNAERSGRVMRRIERRPVIHPRLPTDVDQQDPQAPVNCEQCGLQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPTYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKSFTTAGEQRAHVEHVHLKKPWPKRARQRNHDWKCDEPTVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01339466;
90% Identity: iTF_00112008;
80% Identity: iTF_01118380;