Basic Information

Insect: Orthosia gracilis
Gene Symbol: ZNF296
Assembly: GCA_947562075.1
Location: OX387266.1:63022726-63041089[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.5 47 5.5 0.2 3 23 119 139 117 139 0.96

2 15 0.0021 0.2 13.0 2.8 1 23 353 375 353 375 0.99

3 15 4e-05 0.0038 18.4 0.3 1 23 381 404 381 404 0.96

4 15 0.013 1.2 10.5 2.1 1 23 409 432 409 432 0.94

5 15 1.1e-05 0.0011 20.1 1.5 2 23 613 634 612 634 0.97

6 15 6.2e-05 0.0059 17.8 1.7 1 23 640 662 640 662 0.98

7 15 1.4 1.3e+02 4.1 5.1 1 23 728 750 721 750 0.96

8 15 0.26 25 6.4 0.1 2 23 758 779 757 779 0.96

9 15 0.014 1.3 10.4 2.4 1 23 785 807 785 807 0.96

10 15 0.0016 0.15 13.3 1.7 1 23 813 835 813 835 0.98

11 15 0.0018 0.17 13.2 5.0 1 23 844 866 844 866 0.99

12 15 0.0059 0.56 11.5 2.1 2 23 920 941 920 941 0.97

13 15 0.0044 0.42 12.0 3.8 1 23 958 980 958 980 0.97

14 15 1.8e-06 0.00017 22.6 0.7 1 23 986 1008 986 1008 0.98

15 15 6.1e-07 5.8e-05 24.1 3.1 1 23 1014 1037 1014 1037 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.5	47	5.5	0.2	3	23	119	139	117	139	0.96
2	15	0.0021	0.2	13.0	2.8	1	23	353	375	353	375	0.99
3	15	4e-05	0.0038	18.4	0.3	1	23	381	404	381	404	0.96
4	15	0.013	1.2	10.5	2.1	1	23	409	432	409	432	0.94
5	15	1.1e-05	0.0011	20.1	1.5	2	23	613	634	612	634	0.97
6	15	6.2e-05	0.0059	17.8	1.7	1	23	640	662	640	662	0.98
7	15	1.4	1.3e+02	4.1	5.1	1	23	728	750	721	750	0.96
8	15	0.26	25	6.4	0.1	2	23	758	779	757	779	0.96
9	15	0.014	1.3	10.4	2.4	1	23	785	807	785	807	0.96
10	15	0.0016	0.15	13.3	1.7	1	23	813	835	813	835	0.98
11	15	0.0018	0.17	13.2	5.0	1	23	844	866	844	866	0.99
12	15	0.0059	0.56	11.5	2.1	2	23	920	941	920	941	0.97
13	15	0.0044	0.42	12.0	3.8	1	23	958	980	958	980	0.97
14	15	1.8e-06	0.00017	22.6	0.7	1	23	986	1008	986	1008	0.98
15	15	6.1e-07	5.8e-05	24.1	3.1	1	23	1014	1037	1014	1037	0.98

Sequence Information

Coding Sequence: ATGAACCACACAGCATCCGCTTTACCAGGGCACATGGACATAGATCCATTGAGCTCGTACGAGTACCCTGCGTACGACAGCTATGCAGCCCAGTCCTACCCGTACCCCAGCAAACTGCAGCAGTCCTACCAAGCATACCAACAGAACAACAGCAACTACATCAACACACAACCACAAGAACCGTTCAACAATCCACAACCAGCGTTACAACCACCAATTGAAATTCAAATACAACCTAAAACTGAAGAAACTGAATCAAAACCGGTTTTGAAAAAGCGGAAGAAGGAGAAAAATGGCCAGAAAGGTGCTTATTGTTCTGAGAAGATCACAGATTCTACTTTCAAGTTCTACGGTTGTTCTGTCTGTAATATCAGTTACAATGCACTACATGAATTAGATCAACATGTGACTGTTCACAAAAACAGAATGACGAGCTACAGACTGCGGTTAAGAAACCAAATTAAAAAGAAAAAGATCAAAAAGGAAAAGAAAAAACTAAAAAAGATGGTGAAGATTAAGAAAGAAACATTTGAAATTGAAATTAAACCTGAGGATGGTTATATTGGGGAAGAGAAAGCTACTGATTTTTTGAGTAATGGAATTAATCTTGATACGGGACCCAACAGAAATAACAGTGAAATTAATCTTGATACAGGACTCAACGGAAATAAAAGTGAAATTAATCTTGATACGGGACTCAACGGAAATAATAGTAGAATTAATCCTGATACGGGGCTCAATGGAAATAATAGTGGAATTAATTCTGATACGGGTCTAAACGAAAATATAAATAATGGTTTTATTCCTAACTCTGAATGTAATGGTATGAACTCTAGCTCAGAGTGTAAGAGAAATATAATACATACTGAAAATAGTGCAACAGAAGGTCAAAATAGTCAAATTTACACAAATAATGACTTAAATTCAATAAATAACGAACCTCAGAGAGAAACCAATTCATTGACAAACGGTAACAGTGAAATAAAATCTAATGTGAATAATAAAGACAAGGAGAACAGTATGGATGAAGCGGAATTAACAAATTTAGAGAAAATTTACAAATGTTTTGCGTGTCAAAAACAGTTCACGTTGAGCTATTATTTAAAACTTCACGTGAGATCACATACAGACGAGAAGCCGTACGTGTGCAGCGTGTGCGGGCAGTCGTTCATCACGGCCAGCAAGCTCGGCCGCCACAACAAGCGCATCCACCTCGCCGAGCGCTACCAGTGCCGCGTTTGCTTCAAGATATACTCCCGGTTCGAGTTGCTGACGACTCACTTCGATAAGATGCATCCGGAAGACAAGTTGGAGGGAGAACCGTATGACTACAACGCGATCCTGCCGTACCTCAAGGAGCTGGAGGAACAGTTGCGCGCGCCAGAGCAGAACAGCGTCACGGTGGAACTCAAACTAGAGCAGGACAGCAAGCCCGCGCCTGACGAGCTGTTCTGGGAGGCACAGGTTGGCCCACACGTGGGCCTGCCGCCTGGGGTGGCGCCCACTGATGTCAAGGAAGAGGCGCTCGACGAGGACCAAAAGGACTTGGTGCCGAAGCTGGACATCTTGGTGGAGGAAGTGAAGGTGGACTACGACGCGCCGGTCAAGCGCGAGATGTCTGATGATGAGCCGGACCACCACGGGGGTGATGACAGGAATGAAGAGGATGACAGGGATGTAGGGGACGAGAAGGATGGAGGGGACGGCAGCCAGGTCAAGGACGAGGACAGCCAGTCGGACTCGGACTACTTCCCGTCGAACACGTGGACGGCCCCCCGCGCGGCCTCGCCCCCTCCCCCCCCAGCGCCTACCGGCCGCCCCCGCGGCGCCCCCCTGTCGTGCCCCACGTGCCACAAGCGCGTGAGCAGCGCGTCGTACTTGCGCGTGCACCTGCGCACGCACACCGGCGAGCGGCCCTTCAAGTGTGGCCTGTGCGGGCGCGGCTTCATTACCAGCAGCAAGATGCACCGCCATGTGCTGACACATGCGCAAGACAAAGGCGATCTCAAAACGGAAGCAGAAGACGCAACGCCGGAAATGGACGGCGAAGCTGTCGACCAGCCGGCACACGACGCCGCTAACAAACCAGTGAAGAAGAAATCCAAAATGAAGTCGAAGTCAAAGTCTTCAAAGCTGAAACCTGGCGAGGAGAAGCCGCGTCGCAAGCACCAGAAGCGGCCGCACGCCTGCGAGTACTGCAACCAGAAGTTCCTGCACCTGAACATGCTAGAGATACACAAGCAGTCACACGCGGGCGAAGCCCTGGTGCTGCGCTGCCACTACTGCCTGCAGGACGCGCCCGACCCGCGTGCGCTGGCGGAGCACCAGGACACGCACCAGGGGGCCAAGCCCTACCTCTGCACTATCTGCGGGAACACTTACAAGAAGAGAGAGACCATGATGTACCACCGCAAGCGCCACCAGCCCGACAAGGAGTTCGTGTGCGACGTGTGCTCCAAGCGCTTCAGCGCCGCCTGCAAGCTCAGCAAGCACCTGGTGACGCACCGCGCCGAGCGGTTCGTGCTGCGCTACGAGTGCCCCGTGTGCGCGCACATGTTCAACACGCAGTACCACGTGCACATGCACCTGCGCACGCACCAGAAGGAAGGCCTGATCCTAGAGGAGAATCGCAGCGAGATCTTAGCCATGGTGCTACAGAACGCGCGTAAGATCCCCGCGCAGGCGAGCGGCCCGGCGGCTGCGGCCGGTGTGGGCGCCGGCGCCGGCGCCGGCTGCGTGCCCGACGAGCGCTCGCGCGTGTGCAACATCTGCGGCGAACTGTTCCACCACTTCTACTACCTGGAGGAGCACCTCAAGAGCCACGCCTCCACCATCGCCATCGCCGACCTCGACAAGCAAGACGACAAGAAATACGTCTGCCAAATATGCAACAAAGGTTTCAAACTCCACTATTATCTCAAACTCCACAGCTTCACGCACTCCAAGGAGAAGCCTTTCATCTGCCAGCAGTGCGGCAAAGGGTTCATAACTAAGGGGAAGCTCAAGAGACACCTGGAGACACACACTGGTCTGAAGAAGTACCAGTGCCACATTTGCTACAAGTTCTTCACGCGGCCCAGCTACCTTCGTATTCACGTTCGCACGATCCATGGCACTCAGGACTATAATTTTAGGTTTGACAAAGGTTACGGCTCTATGGGTATGTCGGCCATGACCATGTCCGATGTCAGTCAGAATAGTATATGA
Protein Sequence: MNHTASALPGHMDIDPLSSYEYPAYDSYAAQSYPYPSKLQQSYQAYQQNNSNYINTQPQEPFNNPQPALQPPIEIQIQPKTEETESKPVLKKRKKEKNGQKGAYCSEKITDSTFKFYGCSVCNISYNALHELDQHVTVHKNRMTSYRLRLRNQIKKKKIKKEKKKLKKMVKIKKETFEIEIKPEDGYIGEEKATDFLSNGINLDTGPNRNNSEINLDTGLNGNKSEINLDTGLNGNNSRINPDTGLNGNNSGINSDTGLNENINNGFIPNSECNGMNSSSECKRNIIHTENSATEGQNSQIYTNNDLNSINNEPQRETNSLTNGNSEIKSNVNNKDKENSMDEAELTNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYVCSVCGQSFITASKLGRHNKRIHLAERYQCRVCFKIYSRFELLTTHFDKMHPEDKLEGEPYDYNAILPYLKELEEQLRAPEQNSVTVELKLEQDSKPAPDELFWEAQVGPHVGLPPGVAPTDVKEEALDEDQKDLVPKLDILVEEVKVDYDAPVKREMSDDEPDHHGGDDRNEEDDRDVGDEKDGGDGSQVKDEDSQSDSDYFPSNTWTAPRAASPPPPPAPTGRPRGAPLSCPTCHKRVSSASYLRVHLRTHTGERPFKCGLCGRGFITSSKMHRHVLTHAQDKGDLKTEAEDATPEMDGEAVDQPAHDAANKPVKKKSKMKSKSKSSKLKPGEEKPRRKHQKRPHACEYCNQKFLHLNMLEIHKQSHAGEALVLRCHYCLQDAPDPRALAEHQDTHQGAKPYLCTICGNTYKKRETMMYHRKRHQPDKEFVCDVCSKRFSAACKLSKHLVTHRAERFVLRYECPVCAHMFNTQYHVHMHLRTHQKEGLILEENRSEILAMVLQNARKIPAQASGPAAAAGVGAGAGAGCVPDERSRVCNICGELFHHFYYLEEHLKSHASTIAIADLDKQDDKKYVCQICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRFDKGYGSMGMSAMTMSDVSQNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -