Basic Information

Gene Symbol
-
Assembly
GCA_949775005.1
Location
OX459061.1:10417086-10418054[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.11 22 7.8 2.1 1 23 27 53 27 53 0.88
2 9 6.7 1.3e+03 2.2 0.8 3 23 83 104 81 104 0.88
3 9 0.01 2 11.1 0.5 2 23 125 146 124 146 0.96
4 9 0.22 44 6.8 0.3 1 23 150 172 150 172 0.91
5 9 0.85 1.7e+02 5.0 3.3 1 23 177 200 177 200 0.82
6 9 0.57 1.1e+02 5.5 3.2 1 15 206 220 206 229 0.77
7 9 0.067 13 8.5 2.1 2 23 237 259 236 259 0.96
8 9 4.2e-05 0.0083 18.5 0.4 2 23 267 288 266 288 0.97
9 9 0.019 3.8 10.2 3.3 1 23 294 316 294 316 0.97

Sequence Information

Coding Sequence
ATGTTCCATCTCATAAAAGAAATCAAGGCCATACTAACGTTTACGAACGCCACCCCATACAAGTCCAAGAACGTTCGCTACTACTGCGCCTATTGCTCTACCGACGGACCTCATTTCGAGGACGCCGACGACCTTCGGACCCATACGAGAACAGAACACGTCGGCCATCGAATAGAAAAGATTGAATACGCCATGAGACCTTACTGGATGAACGAGGTACTAAAACTTGACATAGAAAACCTCATTTGTACCGTTTGTTGCGTAGTCATAAACAATTGGAACGAGATGTTCAAACATTTGAAAGATAAACATAATGTAGAGTTAGACCAAGCGTATACCAGAGTTATTCCGTATGTCTTAAGACCGGATTTACAATGCGCGTTGTGCAAAGAATCTTACTCCAACTACCTCCACTTAGACGGGCATATGAATGCTCATTACAACAACTACGTCTGCGATGACTGCGGAGACACATTCTTAGCGCAAAACCGTTTGAAACAGCACTCTAAGATCCACGATACGGGTAAATTCTCTTGCAGTTTCTGTCACaaagttttccttttaaaaaaatacaggaataaaCACGAAGAGATGGTACACAAGCAAACGATGAAGTTCAAATGTCAGTACTGTACGGAGAAGTTCAGCGGTGAGTACTTAAGACATATACATTGCTTGGAAGCTCATCcagataaaattaaaacgacAACTTGTGAATTTTGTGGCGATTGTTTCACTTGGAAACCGTATTATACGGCTCATATTAGGAAGAAACATTCTATCAAAAGGCAGCCGGTTCAGTGCAGTAAATGCGATAAAAAGTTCGTCGGAGACTACGCGCTTAAGGAACATATGCTTCGGCATGTCGATTCGAAGAATTTCGAGTGTCAAATCTGTCATAAACGGTATTTGACTATGAATTCTTTGAAGCAACATGGTAGACAGCATAGGAAGAAGAAGGAAGCGTAG
Protein Sequence
MFHLIKEIKAILTFTNATPYKSKNVRYYCAYCSTDGPHFEDADDLRTHTRTEHVGHRIEKIEYAMRPYWMNEVLKLDIENLICTVCCVVINNWNEMFKHLKDKHNVELDQAYTRVIPYVLRPDLQCALCKESYSNYLHLDGHMNAHYNNYVCDDCGDTFLAQNRLKQHSKIHDTGKFSCSFCHKVFLLKKYRNKHEEMVHKQTMKFKCQYCTEKFSGEYLRHIHCLEAHPDKIKTTTCEFCGDCFTWKPYYTAHIRKKHSIKRQPVQCSKCDKKFVGDYALKEHMLRHVDSKNFECQICHKRYLTMNSLKQHGRQHRKKKEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00758734;
90% Identity
iTF_00112143;
80% Identity
-