Basic Information

Insect: Orthosia gothica
Gene Symbol: THAP3
Assembly: GCA_949775005.1
Location: OX459034.1:56305514-56338950[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.11 23 7.7 0.8 1 23 360 382 360 382 0.94

2 11 0.0024 0.47 13.0 1.2 1 23 389 412 389 412 0.93

3 11 0.35 69 6.2 0.3 1 23 416 438 416 438 0.92

4 11 0.046 9.1 9.0 1.2 1 23 443 466 443 466 0.97

5 11 0.00059 0.12 14.9 0.7 1 23 470 493 470 493 0.97

6 11 1.4 2.8e+02 4.3 0.2 2 21 506 525 506 526 0.88

7 11 1.7 3.4e+02 4.1 0.2 3 23 583 604 581 604 0.94

8 11 0.0049 0.98 12.0 0.6 2 20 620 638 619 641 0.92

9 11 3.7e-05 0.0074 18.7 3.1 1 23 647 669 647 669 0.99

10 11 0.00028 0.056 15.9 2.8 1 23 676 698 676 698 0.98

11 11 4.8e-05 0.0096 18.4 0.7 1 23 704 727 704 727 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.11	23	7.7	0.8	1	23	360	382	360	382	0.94
2	11	0.0024	0.47	13.0	1.2	1	23	389	412	389	412	0.93
3	11	0.35	69	6.2	0.3	1	23	416	438	416	438	0.92
4	11	0.046	9.1	9.0	1.2	1	23	443	466	443	466	0.97
5	11	0.00059	0.12	14.9	0.7	1	23	470	493	470	493	0.97
6	11	1.4	2.8e+02	4.3	0.2	2	21	506	525	506	526	0.88
7	11	1.7	3.4e+02	4.1	0.2	3	23	583	604	581	604	0.94
8	11	0.0049	0.98	12.0	0.6	2	20	620	638	619	641	0.92
9	11	3.7e-05	0.0074	18.7	3.1	1	23	647	669	647	669	0.99
10	11	0.00028	0.056	15.9	2.8	1	23	676	698	676	698	0.98
11	11	4.8e-05	0.0096	18.4	0.7	1	23	704	727	704	727	0.93

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTAAGAACTGTTCTAATGATACGAGAAGAAATAACAAAAGCCATGGGATCACATTTCATATGTTTCCAAAACCGCTGGATCTCCGGAATGCTTGGTTAGAAGCACTAGGTGAACCGGACTGGGAACCCAAAGAGCGGAGTACCATATGCTCCGAACACTTTAGGAACGACGACTTTTATACGACTCAGCGTGGCTTGAGAAGGATCAAGTGTGGAGCTGTGCCTGTTGTCATGACTGAAGCGTTGGGTGATCTTGACGCGCCGGCCGCATTGAGGgtGTGCCGAATATGTCTTGCGATGGACAGGAAGATGTATCACATAAAAGAACACAAGCTGGACCAAATGTATGAGCACATCACTGGATTAATGGCCAGACCAGAAGACCGTCTTCCGCAGCGCGTGTGTTGGGAATGCGCTGGGCGCCTGTTAGCTGCTTGTCGGTTCAGGAGTAAAGCGTTACGGAGTGATGCTGTGCTTCATGATACACTACGCTCTGACACTTATaTAAAAATCCGGGATATTCGCTCAATAAATAGGAAACATCACAACCTAACATCAACTTTAGTACAACAAATAACTGAAAACGACGAGTTCGACCTTCACGTTAAAGACTTAGCCATCAAGACTGAACAGATACCAGATCCGGATACAGCAGAAAACATACCTATAGAGCCGGAAGACATTGACGTCATATCTTTAGCTCCGGCCGATGAAGTTGGCATCAAAGATGAGAGCAGTAATGAAATATTCTTCGAGGAATATGATCAtttcgatgatgatgatgatgatgataaagcgTTGAGTGAAGTGTATGTAGAGAAGAAGGAAACGCCTAAGGTGAAGAAGAAACGGGAGAAGGGGGTCAAAAAGGTCAAGACGAAGAAGTCTGAGGATGAAACTGATCCGGATCATTGTAGTGATAAatacaaaaaaaatgacgtaAAACGTCGACGAAACAACGAAGGTTTCGACGAGAACCTATTCACGATCACACCGCTAACGTACGACCAGCAGATTGAAGAGATCCTAAAGAGACAAGAGAGTTACAACTACACCAGTGCGCCGTACAAGTGCACTATATGCTACCGAGGGTTCCAGATCAAAGATCGGTACACTGCTCATGCTGTGAGACATAGTGAGcaaTGCGGTGCGTACGAGTGTTTTATCTGCAAAACTAGATTGAAGACGAGTCGTGCGCTACGGAAGCACTTAACGGCACAACACACAGAACAATATACCTGTAAGGGGTGTCCGTTTATGACTAGGAAtagGGGAGTAGCGAGAGAACATGAAAAATGGCACGCGGGGACTAAGTACCAGTGTCCACACTGTGCTAGTACGTTTGATAAAATAACAACATACATGGGTCATATTCGTATCAAGCATGTCTCGGACTTCGTGTGTGAACTCTGCGGATACACTTTTGTTAGTAAGAAGGGCATCGAAGTacacaagaagaagaaacaccGGACGTATAAACAGGAGACGACATTAGAAGGGCCGTACTGTGAGATATGTGATGTAAAGTTCATGTCAGAGGACGCACACGAGAGACATCTGAAGTTATCTTCAAGACACAGCAGTGATCATGACCCtaaCCGAATCAGAAACGACTCTCAAAGCATGAACGCGGAACGTAGCGGCCGAGTGATGAGACGTATAGAGAGGAGACCAGTCATCCATCCGCGCTTACCCACCGACGTTGACCAGCAAGACCCGCAGGCTCCCGTCAACTGTGAACAGTGTGGCTTGCAACTTCGTGACTTGCGAGTGTACGCTCAGCACTTCAGACGAGCTCACCCGGACAAGAACCGCACCAAGTACCCCGCGATGAAGACCCCCTGCATGTGCGAGCAGTGTGGCAAGATATTCCAgAGCATGGCCCTCCTAAAAGACCACATGTGGGTCCACACTGGGGAAAAACGTTTCAAATGTGATCGCTGCACGAAAAGCTTCACCCAGAAGACGAATCTGGTCTTCCATATGAGGGTCCACAGCGCGACTCGACCGACCTACGAGTGTCCCTTATGCGGCAAACACTTCGCGTTCTTCAATAATCGGAGACGACATATGTTTATACACACCGGCCTAAAGCCGTTCAAGTGCGACACGTGCGGCAAGTCGTTCACCACGGCGGGCGAGCAGAGAGCTCACGTAGAGCACGTGCACCTGAAGAAGCCCTGGCCCAAGAGAGCGCGCCAGAGGAACCAGGACTGGAAGTGCGACGAGCCTACTGTTGAGGACTGA
Protein Sequence: MRCSVKNCSNDTRRNNKSHGITFHMFPKPLDLRNAWLEALGEPDWEPKERSTICSEHFRNDDFYTTQRGLRRIKCGAVPVVMTEALGDLDAPAALRVCRICLAMDRKMYHIKEHKLDQMYEHITGLMARPEDRLPQRVCWECAGRLLAACRFRSKALRSDAVLHDTLRSDTYIKIRDIRSINRKHHNLTSTLVQQITENDEFDLHVKDLAIKTEQIPDPDTAENIPIEPEDIDVISLAPADEVGIKDESSNEIFFEEYDHFDDDDDDDKALSEVYVEKKETPKVKKKREKGVKKVKTKKSEDETDPDHCSDKYKKNDVKRRRNNEGFDENLFTITPLTYDQQIEEILKRQESYNYTSAPYKCTICYRGFQIKDRYTAHAVRHSEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYTCKGCPFMTRNRGVAREHEKWHAGTKYQCPHCASTFDKITTYMGHIRIKHVSDFVCELCGYTFVSKKGIEVHKKKKHRTYKQETTLEGPYCEICDVKFMSEDAHERHLKLSSRHSSDHDPNRIRNDSQSMNAERSGRVMRRIERRPVIHPRLPTDVDQQDPQAPVNCEQCGLQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPTYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKSFTTAGEQRAHVEHVHLKKPWPKRARQRNQDWKCDEPTVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01339466;
90% Identity: iTF_00112008;
80% Identity: iTF_01117290;