Basic Information

Gene Symbol
-
Assembly
GCA_963555765.1
Location
OY743226.1:84505833-84508907[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.028 3.2 8.9 0.9 2 23 109 131 108 131 0.96
2 20 3.4e-05 0.0038 18.2 0.8 1 23 137 159 137 159 0.98
3 20 4.6e-05 0.0052 17.7 1.1 2 23 170 191 169 191 0.97
4 20 0.00015 0.017 16.1 0.5 1 23 197 220 197 220 0.97
5 20 0.021 2.4 9.4 1.9 1 19 252 270 252 272 0.96
6 20 5.3e-07 6e-05 23.8 0.9 1 23 280 302 280 302 0.98
7 20 3.4e-07 3.9e-05 24.4 2.0 1 23 308 331 308 331 0.98
8 20 0.0038 0.43 11.7 2.3 1 23 341 364 341 364 0.95
9 20 5e-05 0.0057 17.6 2.3 5 23 454 472 451 472 0.94
10 20 4.1e-07 4.7e-05 24.2 0.9 1 23 478 500 478 500 0.97
11 20 0.00024 0.027 15.5 0.5 1 23 511 535 511 535 0.96
12 20 0.00035 0.04 14.9 0.6 1 20 541 560 541 562 0.94
13 20 0.029 3.3 8.9 3.1 1 23 600 622 600 622 0.97
14 20 2.7e-05 0.003 18.5 2.8 1 23 628 650 628 650 0.98
15 20 4.3e-06 0.00049 21.0 0.7 1 23 656 678 656 678 0.96
16 20 0.00038 0.043 14.8 2.1 1 23 684 706 684 706 0.97
17 20 7.3e-08 8.3e-06 26.5 1.5 1 23 795 817 795 817 0.98
18 20 8.8e-05 0.01 16.8 1.8 1 23 823 845 823 845 0.98
19 20 6e-05 0.0068 17.4 0.1 1 23 852 874 852 874 0.98
20 20 0.00013 0.014 16.4 4.8 1 23 880 902 880 903 0.96

Sequence Information

Coding Sequence
atgcaaacgagtACGGACCTGTTTACTCCCGTTCCAGTGGATGTATCCACTCCGAATGCACTTCTGTATCAGCTTAACGATCCAGGCGAAAAGTTTCTCAAGTCGGATGAGTTCTATTCTTTCGGTTTGGACAGTTTTACTGTGCCTGAAATCAGTGACATACCGGCAGCTATATCTAGCCTCAGTCCAATCCCTGAGGAAACAAGTTGTTCTCTTAATGTTCCTCCCTTAGAAGCACTATTCTCTCCAGTTGAGCCAGAACCGTTTAGACAGAAATGTATAATCACAGATCCAGAGTCGAACATGTCCCATATCCAACAGCTTACCTGCGATTTGTGTCCGGAAACGTTTCACTCGGTGCAGGTTCTGCGACTCCATCGTCGCGTTCGTCACATCTCGACAAAAGAATTTCGATGTCGCAAGTGCCCAACTTCTTTCAACTTTGAGTCGAATTTAGTCCTTCACATGGCATCACATGTTTCCAGTTGTAGCACGAAGAGCGACAAAGAGTGTCCCGAATGTAAGATGGTGTTCAAGCGGCTTTCCAGCTTTAAAGGTCATCTCAAGTCACATCAAACGTCGGACCGGTTTCAGTGCCCTCGCTGCGATAAAGAGTTTGATTTAAAAGGATATTATGAGAAACATTTGGAAAAAGCGCACAAGTTCGACGTTAATGGAACTGTGGAGAATATTCTTGCGAAAGTTGTCAGCAAAAGCAGGTGTCGAAAGAGCAGTAAAGTATCTCAGGGGAAGTACTCTTGTACAGTGTGCGCGAAGAAGTTTTTTAAACCATGTTTATTGAAACGCCACGAAGTGTGTCACACAGGAGCGAagccttttcaatgtccagAATGCGAGCAAAGATTCACACAGAAAACTTCGCTAGCTAGGCACATGTTGCAGCATCAGGGCATTAAAGATTATAAATGCCCCAAATGTGGCTGTAGttttgctcagaaaaacaacctcatTGTGCATATAAAGCGAACACATTCGATCGAACCCAACTCGGATAACACCTTTCCCTGTGAACATTGTCCGTGTGTGTTCACCAAGCTCAATAGCGTCAATCGGCATAAGGCGATGGTACATTCGCAAACGGAAGGCACAAAAACCAGCGACGTATTCAACGATGACGACGTTGCCAAGGTCATTGAGCAATTAAAGAGCTTACAAGAGTCGATGAGCATCAAAGACATGCAGCCATCCGCCCTAGAGCTTTCGGTGACAAAACCACCATCACCTGGGCCGATAGTTCGCACTGTGTCGCTTGTCGACACGCTGAAtccgaaaaaagagaaaacatacAAAATGGTAAAAGAAATCATGTACAAGGGACAGCGGACTATAGCGTGTATTTATTGTGATAAGCCGTTCAAAAGACAATTCGATCTGCTGAGaCATCATCGCACCCATACGAAAGAGAAACCCTTTCAATGCGAGATATGTGACAAAAACTTTTCTACAAATTCAGCACTTAAAGTTCACCGAAGTAACCATGTTCTATCGAATGAGAATCAAGCTAAAGTCTATGTTTGTGCAGCATCCGAGTGTGGAAAACGATTTTCTTCCATGAGAAAGCTTGACATGCACACAAGGACCCACACAAGTGCGATATCTTACATTTGTCCTGTCTGCTCCAAAACGTTCACGTCTAAAGCCGGTTTCTCCGCACATAAACATCAAACTGAGGACAAGGAGATTAATATTGTTCGTTCAATTCTCCTTTCTCCAATAAAAGTTGAAGCGAACGAAGCCGAGGAGGCAGAAAAAGATGAAGAGTACTCTAAGAGATGTCATCAATGCTATGTGTGCGGATTGAAGCTACAAAAGCTTTCACACTTGAGGCAGCACGAAGCCACCCATATCGCAGAAAAGCCATTCAAATGCTCCATATGCTTTAGATCTTACACAACACAAAGCTCGCTAAACCTCCATTTTAAAATCCACACCGCTGAAAAGATTCACATTTGTGAAATATGCGATGCGAAATTCATAACCCAATCCCTCCTCAAACGACATATGGTTTCACACAGCGACGAACGAAAATTCGCTTGTCCATATTGTAATGAGCTTTTTAAAACCAGCGACAATTGTAAGAATCACATTCTTACACATGCCCGTAAGCTGTTGGCGACCCCAGAGCTCTCAAAAGAAGACATGACAACAGTAAATTTGGAAGAAGCCATGTTACAACCATTCATTGCGGTTGTTGACAGCCCCCAAAAGACTTTGTCTCCAAAGTTCATTCAATTGGAGTTGGTTAAGAGCTGCAAAAAGCATGATCACAAAAACTTAACAATCGAAACAGTGGCTGATGTACCGAAGAAATTATCAAAGAAATCGGCAGCCCGTTCGGCAAAGCAAATCAATCAGACTGGTCACCGATGCGGAGAATGTGGAAAAACTTTTCGCAAAGCGAGTGATCTGGAACGCCACGCTCGCACGCACACGAAAGAAAAACCATTTTACTGCAGTCAGTGCTCGAAGCGATTCGCCTTGATGTCGACTTTGGTGCAGCATATGAAAACACATGATGCACAGAGGGAGACATATGATTGTCAGGTTTGTGGCAAGAAGTATGCGTCGCAGAAAGTCTTAGTTGTGCATTTAAGAATACACACGGGTGAACGACCTTTTCAATGCGGTGTGTGCAAGAAGACCTTTCGAACTTCAGGCCATAAAATATCGCACATGAAGGCACAtcataaaaagagaaaatacaAATTTGGAACAATTTTTGCGAGAGAATATGAAATCAGTGACGAGGCAAAGTATCATATTTAA
Protein Sequence
MQTSTDLFTPVPVDVSTPNALLYQLNDPGEKFLKSDEFYSFGLDSFTVPEISDIPAAISSLSPIPEETSCSLNVPPLEALFSPVEPEPFRQKCIITDPESNMSHIQQLTCDLCPETFHSVQVLRLHRRVRHISTKEFRCRKCPTSFNFESNLVLHMASHVSSCSTKSDKECPECKMVFKRLSSFKGHLKSHQTSDRFQCPRCDKEFDLKGYYEKHLEKAHKFDVNGTVENILAKVVSKSRCRKSSKVSQGKYSCTVCAKKFFKPCLLKRHEVCHTGAKPFQCPECEQRFTQKTSLARHMLQHQGIKDYKCPKCGCSFAQKNNLIVHIKRTHSIEPNSDNTFPCEHCPCVFTKLNSVNRHKAMVHSQTEGTKTSDVFNDDDVAKVIEQLKSLQESMSIKDMQPSALELSVTKPPSPGPIVRTVSLVDTLNPKKEKTYKMVKEIMYKGQRTIACIYCDKPFKRQFDLLRHHRTHTKEKPFQCEICDKNFSTNSALKVHRSNHVLSNENQAKVYVCAASECGKRFSSMRKLDMHTRTHTSAISYICPVCSKTFTSKAGFSAHKHQTEDKEINIVRSILLSPIKVEANEAEEAEKDEEYSKRCHQCYVCGLKLQKLSHLRQHEATHIAEKPFKCSICFRSYTTQSSLNLHFKIHTAEKIHICEICDAKFITQSLLKRHMVSHSDERKFACPYCNELFKTSDNCKNHILTHARKLLATPELSKEDMTTVNLEEAMLQPFIAVVDSPQKTLSPKFIQLELVKSCKKHDHKNLTIETVADVPKKLSKKSAARSAKQINQTGHRCGECGKTFRKASDLERHARTHTKEKPFYCSQCSKRFALMSTLVQHMKTHDAQRETYDCQVCGKKYASQKVLVVHLRIHTGERPFQCGVCKKTFRTSGHKISHMKAHHKKRKYKFGTIFAREYEISDEAKYHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-