Basic Information

Insect: Ornithoptera alexandrae
Gene Symbol: zfh1
Assembly: GCA_029030555.1
Location: JARDVY010000272.1:12126340-12129515[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0062 0.56 11.3 0.3 1 23 47 69 47 69 0.95

2 8 0.00036 0.033 15.2 3.5 1 23 80 102 80 102 0.98

3 8 1.5e-06 0.00013 22.7 6.2 1 23 111 133 111 133 0.99

4 8 0.0001 0.0094 16.9 1.0 1 21 139 159 139 160 0.95

5 8 0.11 10 7.4 0.1 2 21 422 441 421 442 0.91

6 8 1.1e-05 0.001 20.0 1.4 1 23 739 761 739 761 0.94

7 8 1.5e-05 0.0014 19.6 7.4 1 23 767 789 767 789 0.98

8 8 0.055 5 8.4 7.1 1 21 795 815 795 816 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0062	0.56	11.3	0.3	1	23	47	69	47	69	0.95
2	8	0.00036	0.033	15.2	3.5	1	23	80	102	80	102	0.98
3	8	1.5e-06	0.00013	22.7	6.2	1	23	111	133	111	133	0.99
4	8	0.0001	0.0094	16.9	1.0	1	21	139	159	139	160	0.95
5	8	0.11	10	7.4	0.1	2	21	422	441	421	442	0.91
6	8	1.1e-05	0.001	20.0	1.4	1	23	739	761	739	761	0.94
7	8	1.5e-05	0.0014	19.6	7.4	1	23	767	789	767	789	0.98
8	8	0.055	5	8.4	7.1	1	21	795	815	795	816	0.96

Sequence Information

Coding Sequence: ATGCCGTCTCTTCATCCTGGGGCAGCTAGATCGGCATGCTCGGTGCAAGTCCGTCCGCTGGCAGGCGGGGGTCCGGAGGGCAAGCCGctggaggaggaggaggagcgCGGCGGGTCACCGCTTGGGCCCGGCGGGCCGTACCGCTGCAGCCAGTGCCGCGGCGCGTACCCCTCGCGCGACCAGCTCGAGCGGCATGAGACGCTGCACTCGCCCAGCACTCAGGTGGATACAGACAAATATACTTGCAAGATCTGCCACAAGAGCTTCCTAAACGTATACCGGCTGCAACGTCACATGATTAGCCACGACGAGAGCGCCGTCCTGCGCAAGTTCAAATGCAACGATTGCGATAAAGCTTTCAAATTTAAGCACCACCTCAAGGAGCACCTGAGAATACACAGTGGTGAGAAACCTTTCGAGTGTGCAAATTGTGGCAAGAAATTCTCCCACTCTGGTTCCTATTCGAGTCATATGACTTCCAAAAAATGCCTCGTGATGAACCTGAAAATGGGTCGAATAAAACCTAATAATCCTGCTCTAAATCCCGATCGTAGTCCTTCACGAAAACGGACTAATGCGATGGTCGTATCGCAGCTTAACAACAACATAGTACCAAACGGAAACTCATTTTTACCCATAATGCCAAAATATAATGATGCTTCTGCCTTCTTCGCCTCGATGTCCTCGCAAGAGAACAACTTTCACCGTACTCCTCTGGGTCAACCTGGAATTAATCCATTCTACATGCCGCCGGGCATGCCCATGAGTCCTGCAAGTGGAATTACGCCGTATAGTTTTCCCACTTCCCTCAGTCAACTATTTGAGCAAATAGCTTCAACGCAATATCAACAAAGAAAAATTGAAAACGTTATTAGTCCGAAACTTAATAGTCCAACACCAGCAGACCACGAAGAGTTGATAGAGGAAGTTACAGAAGAGGATGACAAGCGATCTGAGGGAAGCGCAGAACTCGTGATGGACATCGAGGAAGATGACAATATCACTGTTAAAAAAGAGCAGGAAGAGGGTGAAACTGAGTTTCGACCCCATTCATTCAACTATATAACTCACTCTAACACTGAGCTAGACGATAATGATCCAAGTTTTGATAAAGCGTTAAAAGCTCTGCGGGCCAGAGTGACAAAGCACTTCTTCAGAACGAAAATTGAGACTATGTCTCCTGTTCCAGCACAGATGATTTCCGATCCAAATCTGCCACCCTCGCCccgtgttttaataaaaaacgagGTAGTTGATGACCTCGTATGTGTCAAATGCAATATGTCTTTCCAGGTCAAAAACGATTTAATAGAACATGAAAAACTAGCTTGCGAAAATCTGTTTAGAAAACATGAAGGACTTGCAGCACAAGTAGCTGAAACTGTAGCTCTCAACAGATTAGAGGCGGAAATGCGCGCTTCCATACAGAGCGGAGTGAACGCAAGTGATGACGAAGAATTTGCCAAAGATGAGCGCGACGATAAAATATCTGTTCAAGACACGGACAGGAAAATCAGAGTGCGAACTGCTTTAAGTGAAGAGCAACAATTGATTCTAAAAGAACATTATGCCGTAAACCCTCGGCCGAATCGCGAAGAATTTAAGAAAATCGCACAACAAATCAGTTTGGATAATCGCGTGGTTCAAGTGTGGTTCCAAAACAACAGAGCTAGGGTTCGAAGGATGACGCAAACTATCGCCTTATCTGATCAACCTCTAGACTTatctacaaaaaaatctaatttatctGTCACCTCAAGCCCGTCCCCCTCACCGCCTTGTAGCATTTCGATGACACATTCCGACTCCGACGAAGCGGTAAACCTGAGCCAGAAGTCATCCCGGAGTACCACCCCGCACCACACCAATCACGTTAATACCTATTCACATTCCAACTGTTCGTCATCTTCTTTCACTGACTTTAGACTCTCGCCGTCGCCGGTGGACATAATGATAGGTCCGAAACGATTGCTTTCGCAGAAAATACCAATCAATCCTATCATGCCAATGGATAAAATTCTACAATACAGCGACATGTCCAAGGGACGGTCGCCGATTCTCAACGTGCAGCCTGCGGATCCCAACCGGCAGGCGCTGAGCCCGTACGATCGGCCTTCGTGGGATGACGCCCACTGCCCCAACGAACTCGATGACGACGCGTCGCTGCTTAAGAAGAGCAAACTGAAAGCCGAACTGAAAGAAGGCGAAGGACAATTCATTTGCAATCAATGCGACAAAACCTTCGTGAAACAAAGCTCTCTGGCGAGGCACAAATACGAGCATTCAGGACAAAGACCCTACAAGTGCGAGGAGTGTCCCAAAGCATTCAAGCACAAACACCATTTGACAGAGCACAAGCGCCTGCACACGGGCGAGAAGCCGTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCACACTCCGGCTCCTACAGTCAGCACATGAACCACAGGTTCGCAATCTGCAAGCCCTACCGTGACTAG
Protein Sequence: MPSLHPGAARSACSVQVRPLAGGGPEGKPLEEEEERGGSPLGPGGPYRCSQCRGAYPSRDQLERHETLHSPSTQVDTDKYTCKICHKSFLNVYRLQRHMISHDESAVLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRTNAMVVSQLNNNIVPNGNSFLPIMPKYNDASAFFASMSSQENNFHRTPLGQPGINPFYMPPGMPMSPASGITPYSFPTSLSQLFEQIASTQYQQRKIENVISPKLNSPTPADHEELIEEVTEEDDKRSEGSAELVMDIEEDDNITVKKEQEEGETEFRPHSFNYITHSNTELDDNDPSFDKALKALRARVTKHFFRTKIETMSPVPAQMISDPNLPPSPRVLIKNEVVDDLVCVKCNMSFQVKNDLIEHEKLACENLFRKHEGLAAQVAETVALNRLEAEMRASIQSGVNASDDEEFAKDERDDKISVQDTDRKIRVRTALSEEQQLILKEHYAVNPRPNREEFKKIAQQISLDNRVVQVWFQNNRARVRRMTQTIALSDQPLDLSTKKSNLSVTSSPSPSPPCSISMTHSDSDEAVNLSQKSSRSTTPHHTNHVNTYSHSNCSSSSFTDFRLSPSPVDIMIGPKRLLSQKIPINPIMPMDKILQYSDMSKGRSPILNVQPADPNRQALSPYDRPSWDDAHCPNELDDDASLLKKSKLKAELKEGEGQFICNQCDKTFVKQSSLARHKYEHSGQRPYKCEECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00840502;
90% Identity: iTF_00180732;
80% Identity: iTF_01115600;