Basic Information

Gene Symbol
-
Assembly
GCA_963971445.1
Location
OZ020532.1:525427-528287[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.037 3 8.8 0.2 1 21 207 227 207 228 0.94
2 12 0.00043 0.036 14.9 2.8 1 23 319 341 319 341 0.99
3 12 5.1e-07 4.2e-05 24.1 0.4 1 23 347 369 347 369 0.99
4 12 1.4e-06 0.00011 22.8 1.1 1 23 375 398 375 398 0.95
5 12 0.017 1.4 9.9 4.1 1 21 404 424 404 426 0.95
6 12 7.4e-06 0.00062 20.5 2.7 1 23 432 454 432 454 0.99
7 12 6.6e-05 0.0055 17.5 2.1 1 23 460 482 460 482 0.98
8 12 9.7e-05 0.008 17.0 1.2 1 23 490 513 490 513 0.97
9 12 0.0007 0.058 14.3 0.2 2 23 520 541 519 541 0.96
10 12 0.00056 0.046 14.6 1.1 1 23 547 569 547 569 0.98
11 12 3.8e-06 0.00031 21.4 0.8 1 23 575 598 575 598 0.97
12 12 5.4e-06 0.00045 20.9 4.8 1 23 612 634 612 634 0.96

Sequence Information

Coding Sequence
ATGGCAGAGGAAGCGGAAGATCAACAAATAGAAGCCTACATAGGAGCATTGGATGAAGACTGGACAGAAGAAGGGGAGGAAGAGGAGACAGAAGACGACGTTGTCCTTACCTCAGAAGCACTTGAAGCTTTGGCTGATGTGGATGCTGTAACCAAGCATGTACTCCAAGGTGATATTAATGGTGACGATGCTAATGAAACAAATGGTACCATAATCATGGATGCCGATggcaattattattttcataccTCAGAAAAAACAATCGAGGTAAAACctttaaaatttaatgattCATCAAAGTTGATCAAAATTCAGAATGCTACGGTAATCAAAAAAGGTATCAAAGGATTCAAACCTGATGAACTAGCGAAACATTCAAAAGCCGTCGCCAAAAAGAATGGGAATAAAGATGCTAAAGGTAATGGAAATATTATTGTAGGAGATCAAACGTCAACTACGGACGAAATCAATACAAAACAAACTGACCTAAATGCCTATGAATTAATCATTCCCGAAACAGAAGCAGAGTTTTAtgctttaaataaaacaaacaccaATGAGGCGGACCAACAGCATACCACAACTGCCACTGAAGCAGCGATGCATACTATGACTGTGTACGATTGTAAGAATTGTACGTTTAAAACCAACAGTGCAGACTTGTTGGAAAATCACTTGGAAACGTGCGgaaaaattaaagaagaaaaaaaacaagaaacagCAGCACTGGTGAAACCCAAAGTTGGACGTCCAAGTAAAAAGTACAGTTCGAGCAAGAATAAGGAGAAGAGCAAAAACACAACTTCAactaagaaaaaagaaaaacaacaacaggaTGAATATATGAATGATGAATACGAAGTTAACGATCCCGACTACAACCCCGAAAATGAAGTTGAAGTACGTTCGGAAGCGTTAATGAAATCTATAACCGGTGACACACCAAGTGAAGAATTCAAGTGTCCGCATTGTTCGTATGTGGCCCCAAAGAAATTCTCGTTGTCGCGTCATCTAAAAACACATTCCGATGATCGGCCCTACAAGTGTTCTATATGTGAGAAGGGTTTCAAAACGGCCGCTTCACTACAAAATCACGTCAATACCCATTTGGGTAATAAACCACATGTGTGCGGTGATTGTGGCAAATCGTTTACAACCTCGGGAGAGTTGGTGCGCCACTCACGCTACCGTCACACGGGTATTCGGCCCCATAAGTGTACCGAATGTGATTACGCCAGTGTGGAGATGAGTAAGTTGAAGCGTCACATGCGCTGCCATACGGGCGAAAGGCCGTACCAGTGTCCACACTGTACATACGCCTCGCCCGACTCGTTTAAATTGAAACGTCACATGCGCACGCACACCGGCGAAAAGCCCTATGAATGCGACATATGTCATGCTCGCTTCACACAATCGAATTCTCTTAAATATCATCGTTTAATACACTCGGTGAATGAGAAGCCGGTGTTCCAGTGTCCCATGTGCCCCACTACATGTGGCCGCAAAACAGACTTGCGCCTGCATATACAAAACCTGCACAGTACGGATAAAGCGTGGCCCTGCAATCGCTGTGGCAAAGAGTTGCCGGATCGGTACAGTTACAAAATGCATATAAAATCTCATGAAGGTGAAAAGTGTTTTCAATGCAAATATTGTCCGTATGCTTCAGTCTTGCAGCGTCACCTCAACATACATATGCTGCTACATACTGATGAAAAGCCATTTAAATGTGATACATGCGATATGCCCTTCCGCCAAAAGATGTTGCTGCAACGTCACATCAACGTCTATCACACTGGGGAGTATGTACCGCCGAAGCCGCGGGAGAAATCGCATGCTTGTCCACATTGTGAAAAGACATTCTGCTTCAAAGGCAATTTAATACGTCACATGGAAATACATGATCCCACATCAGCCGTGGAACAGCGTCAATTTGAATTAAAGTTGGGTCGTTTAATTCGCGTTAGCGATGAAAGGAACAAAATAAACGAGGATGCCGAAATTGCTGCAAACGGTGATGGTGATTACAATGAAGCAGACGATGATGAGGGGGCAATTGTGGAATCGTTGGTTGATCATAATGAATTAGAATACCACAATGAAGTAGCGGATGATGAGAATGATGAAGAAGAGGAGGCCTACTATTTATACGAAGAAATTGAAGAGGACGAAAAACCTTCACTAATGAATTCTctagaatatgaaaataaaaacatttcacaaataaaaccagcaacaaaacaaactataaataaagtaaaaacgGAAAAGGAACAATTGAATAATGTCAAAGTAGAAAAAGAGACATCcgataatgttgttgttatagaaATAATGCAATGCGCGGATGATACTTTAATGGAGGACGAAGAGGAAACTAATCTTATGGAAACATCAGAAATACAAGAAGAAAGAGAAAAccacaagaagaagaaaatgaataCAAATCAAATTATAGATGATACTAAAAATAATACCGTTATTTTTGAgGAAGTAGCTAATGCCGAATTAATGGAAGACGATCAACGtattgaattttttgaaataactgAAGCTAATTAA
Protein Sequence
MAEEAEDQQIEAYIGALDEDWTEEGEEEETEDDVVLTSEALEALADVDAVTKHVLQGDINGDDANETNGTIIMDADGNYYFHTSEKTIEVKPLKFNDSSKLIKIQNATVIKKGIKGFKPDELAKHSKAVAKKNGNKDAKGNGNIIVGDQTSTTDEINTKQTDLNAYELIIPETEAEFYALNKTNTNEADQQHTTTATEAAMHTMTVYDCKNCTFKTNSADLLENHLETCGKIKEEKKQETAALVKPKVGRPSKKYSSSKNKEKSKNTTSTKKKEKQQQDEYMNDEYEVNDPDYNPENEVEVRSEALMKSITGDTPSEEFKCPHCSYVAPKKFSLSRHLKTHSDDRPYKCSICEKGFKTAASLQNHVNTHLGNKPHVCGDCGKSFTTSGELVRHSRYRHTGIRPHKCTECDYASVEMSKLKRHMRCHTGERPYQCPHCTYASPDSFKLKRHMRTHTGEKPYECDICHARFTQSNSLKYHRLIHSVNEKPVFQCPMCPTTCGRKTDLRLHIQNLHSTDKAWPCNRCGKELPDRYSYKMHIKSHEGEKCFQCKYCPYASVLQRHLNIHMLLHTDEKPFKCDTCDMPFRQKMLLQRHINVYHTGEYVPPKPREKSHACPHCEKTFCFKGNLIRHMEIHDPTSAVEQRQFELKLGRLIRVSDERNKINEDAEIAANGDGDYNEADDDEGAIVESLVDHNELEYHNEVADDENDEEEEAYYLYEEIEEDEKPSLMNSLEYENKNISQIKPATKQTINKVKTEKEQLNNVKVEKETSDNVVVIEIMQCADDTLMEDEEETNLMETSEIQEERENHKKKKMNTNQIIDDTKNNTVIFEEVANAELMEDDQRIEFFEITEAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00384717;
90% Identity
iTF_00384717;
80% Identity
-