Basic Information

Insect: Ormyrus thymus
Gene Symbol: zfh1
Assembly: GCA_035582935.1
Location: JAWWEM010000010.1:25442197-25446246[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.3 40 5.9 1.0 2 23 116 138 116 138 0.89

2 7 3.3e-05 0.0044 18.3 0.6 2 23 159 180 158 180 0.97

3 7 7.7e-06 0.001 20.3 7.8 1 23 189 211 189 211 0.99

4 7 1.9e-05 0.0026 19.0 1.9 1 21 217 237 217 238 0.95

5 7 2.4e-05 0.0033 18.7 3.4 1 23 777 799 777 799 0.95

6 7 0.0016 0.21 13.0 12.8 1 23 805 827 805 827 0.98

7 7 0.002 0.27 12.7 4.3 1 21 833 853 833 854 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.3	40	5.9	1.0	2	23	116	138	116	138	0.89
2	7	3.3e-05	0.0044	18.3	0.6	2	23	159	180	158	180	0.97
3	7	7.7e-06	0.001	20.3	7.8	1	23	189	211	189	211	0.99
4	7	1.9e-05	0.0026	19.0	1.9	1	21	217	237	217	238	0.95
5	7	2.4e-05	0.0033	18.7	3.4	1	23	777	799	777	799	0.95
6	7	0.0016	0.21	13.0	12.8	1	23	805	827	805	827	0.98
7	7	0.002	0.27	12.7	4.3	1	21	833	853	833	854	0.96

Sequence Information

Coding Sequence: ATGCGCACTGGGGATCTCGTCGATAACGGAGTGGGCACTGCACGCTTCGAGGGTTTATCGAGAGCCAAAATTCGTAACAAACGTCCTCCATTCGTTCCAGCAGGCTGCAGCGGCGACGAGGCAGGTGCCGACGCGGAAGTGGGCGGCTGCGCGAACGGCGTAGGTAATGGTGGGAAAGGCGCCGGCGGCGAGGGCGGCGCGGAAGGAggcaccaccaccaccaccaccaccactagcagcagcggcggcggcggcggcggcggcagcgccggCAGCGACACGAGCAACAGCGCGGCAaacagcggcagcggcggcggcggcggcagcaagCAGCCGCCGTGCGAGAGGTGTCCACAGTGCGACGTCGTCTGCCGGAACTCCCGCATACTCCAGCTCCATCTCGAGGACAAGCACAAGGCGGCGGCGCCCGGCGGCTACGCCATCGACAAGCACAACCTTCAGTTCTCCCAAGTTTCATGCAAGGTGTGCAGTAAAACTTTCGCAAACGTGTACCGACTACAAAGGCACATGATCAGCCACGAAGAAAGCGCGGTACTCCGCAAATTCAAATGCCCTCACTGCGAAAAGGCCTTCAAATTCAAACACCATCTCAAGGAGCACTTAAGAATACACAGCGGGGAGAAGCCCTTCCAATGCAACAACTGTGGCAAGCGATTCTCCCATTCGGGCTCCTACTCGTCGCACATGACGTCGAAGAAGTGCCTCGTGGTCAACAACAAGAAGGCCCGGCAACAAAACTCCGTAAGCAACGTAGCCAATGCCGAGCGCGCCTCTGGCCTTAAGAAGCCCCAACaacagcagccgcagcagcagcagcaacaacagcctCAGCCGCAACAACAGCACCCGACGATCGACATAAGACGCGATGTCGAACTTCTTGCCGCCAACAATAACAGTTACATGCCTATTCTGCCTAAGCTTTCGCCGTCGGATTACCGTGACATTCAGCGCGATGCAGCAGcCGCGGGTATTTACGACATGCCTACGCTTCTACCTCACATGATGGGCTTCGGAAACTACTTTCTGCACTCGGTAATTGGCAAACTTCTCAATCAAGTGCACGCCACGCAGCAGGAGCAGCCGCAAACTCGCCAACAAAACAATCACCACAACAATCAGCACAACAATCAGTACAATAATCAGTACAACAATCACCGCTCAGATGAGGCGACTAGCGAGCATTGCGAAGCTTTGAGCCAGCAGAGCGAGACGGCTTTGAGCCCGTCGACGACAGTTCCGGACTCCGAAGGTACGTCCGAGGGCACCGAGGGCGGTAAAGACTCGCCAGCGCCGCCCCCGCCGGCCCTCCTTCATCTCTATCATCCGGAACAGTCGCAAGGCCTCGATGTCGTTAGACGACTGCTCGAAACTGTCAATACGTCGGTTACAAAGCAGCTGCTCGAGGCTAACGTGAGAAAACTCGCGACATCGCCTCCACCGCCTGCGGTGATTCTTCGAGAATATGATGAGGACTATCAGGATCAAGACAGTGAGATGTCGAGCGAGATGGCACACTACCCAGCTGATTGGTCAGCTACGGAGCAGGGTGACTCTCAAAGTGAAGGTCTCGCGGCGAAGCTCGAAGAAGCCCATCAGAAGAATAGTCCTGCAGTTCGCAAGGCTGTCAAACGCAAAGCCGAGAATGGTCTTTCAACGCACACCTCGGAAGTCGACAGCGAAGAAGAGGAACACCATCAGCAAGACAACGCTGCTAACGGCTCCACGCGTAGGGTAAGGGCTAGATCGCTGATTGACGATGAACAACTCGCGGTGCTCAAGAGTTACTACGCCATCAATCCTCGGCCTAAGAAGGAAGATATTACAGCAATTGCCAACTACATTAATTTCCCTACGCGTGTCGTTCAGGTTTGGTTCCAAAACTCACGAGCTAGAGATCGTCGTGAAGCTAAAATACCAGCACTGGTGCCTCTTTCGAGCTTGAACAATCATCATATGTTTAATGATCAGCCTCTTgatctttcaaaaaaagatGTGTTTAAAACAATATCCACAACGAAGGAAAACGGTGATATTTCAAGTAGAAATGCGGCCTCACCTGCCGATATAAAAAGCGAagtatttataacaaaaataccAGCTAATAATAATGTAGAGCCTGAAGACACCGAAGAGTCACGTCTCGTTATTGATGAAGAGACAGCTGATTCCGTTGATGTCAAACCTCCAATTATGCCTGTCGAGGTTATTATGAAGGCGGAATATCCAACTGTGCAAATCAAAACCGAAGATACTAGAATAAATACTGATCTGCCATCGCAGACAGAAGGGCAACAAGAGGGCGCATATCCTTGCAACCAGTgcgataaaacttttacaaagcACAGTTCCCTTGCAAGACATAAATATGAACATTccgGGCAAAGGCCGCATAAATGTCCGCACTGCACGAGAGCATTTAAGCACAAGCATCACCTAACGGAACACAAGCGACTGCATAGCGGCGAGAAGCCCTTCCAGTGTTCCAAGTGCCTCAAGCGCTTCTCCCACTCTGGCTCCTACAGTCAGCATATGAACCACCGTTACTCTTACTGCAAGCCTTACAGAGAATAG
Protein Sequence: MRTGDLVDNGVGTARFEGLSRAKIRNKRPPFVPAGCSGDEAGADAEVGGCANGVGNGGKGAGGEGGAEGGTTTTTTTTSSSGGGGGGGSAGSDTSNSAANSGSGGGGGSKQPPCERCPQCDVVCRNSRILQLHLEDKHKAAAPGGYAIDKHNLQFSQVSCKVCSKTFANVYRLQRHMISHEESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLVVNNKKARQQNSVSNVANAERASGLKKPQQQQPQQQQQQQPQPQQQHPTIDIRRDVELLAANNNSYMPILPKLSPSDYRDIQRDAAAAGIYDMPTLLPHMMGFGNYFLHSVIGKLLNQVHATQQEQPQTRQQNNHHNNQHNNQYNNQYNNHRSDEATSEHCEALSQQSETALSPSTTVPDSEGTSEGTEGGKDSPAPPPPALLHLYHPEQSQGLDVVRRLLETVNTSVTKQLLEANVRKLATSPPPPAVILREYDEDYQDQDSEMSSEMAHYPADWSATEQGDSQSEGLAAKLEEAHQKNSPAVRKAVKRKAENGLSTHTSEVDSEEEEHHQQDNAANGSTRRVRARSLIDDEQLAVLKSYYAINPRPKKEDITAIANYINFPTRVVQVWFQNSRARDRREAKIPALVPLSSLNNHHMFNDQPLDLSKKDVFKTISTTKENGDISSRNAASPADIKSEVFITKIPANNNVEPEDTEESRLVIDEETADSVDVKPPIMPVEVIMKAEYPTVQIKTEDTRINTDLPSQTEGQQEGAYPCNQCDKTFTKHSSLARHKYEHSGQRPHKCPHCTRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01112106;
90% Identity: iTF_01112939;
80% Identity: iTF_01113303;