Othy030442.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ormyrus thymus
Gene Symbol
-
Assembly
GCA_035582935.1
Location
JAWWEM010050649.1:1939-7206[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.021 2.8 9.5 3.2 1 23 293 315 293 315 0.99
2 16 2e-06 0.00027 22.1 0.9 2 23 322 344 321 344 0.94
3 16 0.19 26 6.5 2.5 1 23 350 372 350 372 0.98
4 16 3.5e-06 0.00048 21.4 2.6 1 23 378 400 378 400 0.96
5 16 0.00035 0.047 15.1 0.6 1 23 406 428 406 428 0.98
6 16 0.00022 0.03 15.7 1.1 3 23 436 456 434 456 0.98
7 16 8e-05 0.011 17.1 2.3 1 23 462 485 462 485 0.96
8 16 0.00097 0.13 13.7 0.1 1 23 521 544 521 544 0.98
9 16 3.6e-05 0.0049 18.2 4.2 1 23 558 580 558 580 0.98
10 16 1.3e-05 0.0018 19.6 0.8 1 23 604 626 604 626 0.99
11 16 0.00016 0.022 16.1 0.1 2 23 633 655 632 655 0.93
12 16 0.0079 1.1 10.8 0.2 1 23 661 683 661 683 0.96
13 16 0.0029 0.39 12.2 3.0 1 23 689 711 689 711 0.96
14 16 2.1e-05 0.0028 18.9 2.7 1 23 717 739 717 739 0.99
15 16 9.6e-06 0.0013 20.0 0.7 1 23 745 767 745 767 0.97
16 16 0.00068 0.091 14.2 2.8 1 23 773 795 773 796 0.93

Sequence Information

Coding Sequence
atgGACGAAACAAGTAATGTTCATATTGTGGCCATCAGCAATGATGGAATTATCATACGTGATTCAAAAGGGCTCACAGAAAAGggtgaagaaataaaaacgacTGAATATTTCTTAGATGTTGAAGACCAACACATAGAAGAAGGAGATCTAGATGCACAATATGTGACTGTAGAAAATGTATGTAAAGAAAACGAAAGCGAGCAGTACATAGCTGTCGATGTTGACGATTCCAGTGAAATCATTTTAGAAGATAAAGAAGTAATATTATGGAACGAACTCTGCCGAATATGTGCCAATGGAAGTGATCGATTTGTTCCAATATTCAGTGATGAAGGATTAGAACATGATTTGTGtaacaaaattcaaacttatttACCATTAGaggTAACTGAAAATGATAGTCTTCCTCATCAGTTATGCTACAACTGTGCAGCAACTTTATTGGCATGGCATGACATGTTTAAAGGTTGTCTTGATGCTCAACAACGTCTTGAggaaatgcaaaataaatttcatttgaaggATCAGgaTTATAATGATTCTGCAAATGAGGAAGAAAGTATTCACGTTGCTCCAGAGGTGGAAACGGATATCGAAGAAAcaaaaatacaCAATAAAGAAATGGAAGATGTACAAATGGAACAAATCATTGATGGGACTAATTCAGACAGATGCGTGGATATTTCGGACGGTGATGTGATCTGCACCATCCTAACGACGGTGTCAACAGCCTCGGCACCCAGAGGGCGACGACAGCGAAAGACCAAGGATCTGGCCATCAAAAGAGCAGCAACGAAAGCGACAAATCCTCAAAGTCTACAGCGTCGCATGGAAGCAGCTCAGGCTAAAGTGGTTGCCAATGGAGTTACGTACTATAAGTGTGGCACATGCATGAAACATTTGTCGACAGCGTATAACTACTTTGCCCACAAACGCATTCACACGAAGGAGAAGCTATGCACATGCGAAATGTGTGGCAAAAGCTTTACTGCCGCCTCATCTTTGACAAGGCACGTGCGTGAGGTTCATTACCAAATCAAGGAATATTGTTGTAGTTTTTGCGATAGAAAATTGGCTTCAAAAATCGCGAGAGATGAACATCAGAGAACTCATACGGACGAGCGACCGCATGTATGTGATCAATGTGGCAAGAGTTTTAGGCAAAGAGCTTCTCTAAATGTGCATAAACGGTTTCACTCAACAACTTTTATGTTTAAATGTACTCTCTGTGCAAGGGGATTCCCTCGAAAACAGGATATGGAGAGGCATGAACTCACGCATACTGATCAGAAACCATATGGGTGTAAATTGTGCAGTAAAACTTTTAGAAGCTCAGCATCGGCAATTAGACACAGACAGACCCACGAAACAGAATGTAAACATATGTGTGAGGAGTGCGGAGAAAGTTACACTCAGGAAAGATATCTAAAAAATCATAAGAAAAAAGTACACAAAAGGCTATCCCATGTCTTTCATTACAGAGATTTCTCGTCGTatgatgaaaatgaagaaCAAGAAAGCCAGGATTCAAATCAAAAGCAAGATGAAGACTTCGTGTACATGTGTGGCGTATGCGATGAATTCTACGAATCTGAACAAGCTGTAATGCGTCACATGCGCAGTAATCATTCGGAGCACATAAACACTAAGACGCTAAATCCAGTTTGTTATGAGTGTCACATATGTTTTAAAACCTACAGACGAAAGCAATATTTGGTCAAACATCTGGAGAGTCATACCGTGGAGTTACCTGGCGAGGATGGCATCGTCGAAAAAGCCAAGATTTTTCGCAATCACGTTTTAACTTATAAATGCGATAATTGCGGACAATCTCTAACGAACCGTCGAGCCTTTATTCGTCACGTTAGGATGCACGCAGATGAAAGACCAATTGTCTGTGATGAATGTGGGAAAAGGTATCGCATCGAAGACGATCTGAAGCGTCATGTTAACGACGtgcatcgaaaaattaagcgaTTTCCTTGCGATCTTTGCGGCAAGTTTTTCGCTGCCAAAATGACCCGTGACGCTCATCGGCGAATTCATACAGGCGAGAAACCTTTTACCTGCGATCAGTGTGGAAAACACTTCCGCTCAGTTAATCTTCTGGGAGTGCACAAACACATTCACACAGACTATCGCCCCTATGAATGCTCATATTGCCAAAAAACCTTCAGGAATAGACAGAAGGTTACAATACATGAACGGACTCATACCGGTGACAAACCCTTTTCTTGTGATATTTGTAACAAGATGTTTTCGTCAAAGGGCGAAGTTATGAGGCACCGAACGATTCATTCTAATGAAAAACCATATCTATGCTCCGAGTGCGGTCTAAAATTTAGATTGAATAGATACTTGAGAATGCATATCAAGCAGCATCACCCCGACAAGGCTGAGGAGTTGTTTAATGCTATGCAGAGAAGTTAA
Protein Sequence
MDETSNVHIVAISNDGIIIRDSKGLTEKGEEIKTTEYFLDVEDQHIEEGDLDAQYVTVENVCKENESEQYIAVDVDDSSEIILEDKEVILWNELCRICANGSDRFVPIFSDEGLEHDLCNKIQTYLPLEVTENDSLPHQLCYNCAATLLAWHDMFKGCLDAQQRLEEMQNKFHLKDQDYNDSANEEESIHVAPEVETDIEETKIHNKEMEDVQMEQIIDGTNSDRCVDISDGDVICTILTTVSTASAPRGRRQRKTKDLAIKRAATKATNPQSLQRRMEAAQAKVVANGVTYYKCGTCMKHLSTAYNYFAHKRIHTKEKLCTCEMCGKSFTAASSLTRHVREVHYQIKEYCCSFCDRKLASKIARDEHQRTHTDERPHVCDQCGKSFRQRASLNVHKRFHSTTFMFKCTLCARGFPRKQDMERHELTHTDQKPYGCKLCSKTFRSSASAIRHRQTHETECKHMCEECGESYTQERYLKNHKKKVHKRLSHVFHYRDFSSYDENEEQESQDSNQKQDEDFVYMCGVCDEFYESEQAVMRHMRSNHSEHINTKTLNPVCYECHICFKTYRRKQYLVKHLESHTVELPGEDGIVEKAKIFRNHVLTYKCDNCGQSLTNRRAFIRHVRMHADERPIVCDECGKRYRIEDDLKRHVNDVHRKIKRFPCDLCGKFFAAKMTRDAHRRIHTGEKPFTCDQCGKHFRSVNLLGVHKHIHTDYRPYECSYCQKTFRNRQKVTIHERTHTGDKPFSCDICNKMFSSKGEVMRHRTIHSNEKPYLCSECGLKFRLNRYLRMHIKQHHPDKAEELFNAMQRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01110362;
90% Identity
iTF_01110362;
80% Identity
-