Othy009960.1
Basic Information
- Insect
- Ormyrus thymus
- Gene Symbol
- -
- Assembly
- GCA_035582935.1
- Location
- JAWWEM010000943.1:3570-5336[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.0013 0.18 13.3 1.6 1 23 15 38 15 38 0.97 2 19 1.8e-05 0.0025 19.1 0.4 1 23 44 67 44 67 0.98 3 19 3.7e-06 0.0005 21.3 1.0 1 23 73 96 73 96 0.94 4 19 0.00033 0.044 15.2 0.1 1 23 102 125 102 125 0.94 5 19 1.1e-05 0.0015 19.8 1.1 1 23 131 154 131 154 0.94 6 19 0.1 14 7.3 0.2 1 10 160 169 160 183 0.83 7 19 3.2e-06 0.00042 21.5 0.8 1 23 189 212 189 212 0.94 8 19 8.6e-06 0.0012 20.1 0.2 1 23 218 241 218 241 0.96 9 19 8.6e-07 0.00012 23.3 0.2 1 23 247 270 247 270 0.97 10 19 4e-05 0.0054 18.1 0.3 1 23 276 299 276 299 0.98 11 19 2.7e-06 0.00036 21.7 0.9 1 23 305 328 305 328 0.94 12 19 0.00037 0.049 15.0 0.1 1 23 334 357 334 357 0.94 13 19 1.2e-05 0.0016 19.7 1.1 1 23 363 386 363 386 0.94 14 19 0.07 9.4 7.8 0.2 1 12 392 403 392 415 0.70 15 19 9.3e-06 0.0012 20.0 0.5 1 23 421 444 421 444 0.94 16 19 4.4e-05 0.0058 17.9 0.5 1 23 450 473 450 473 0.98 17 19 8.6e-07 0.00012 23.3 0.2 1 23 479 502 479 502 0.97 18 19 7.1e-06 0.00095 20.4 0.5 1 23 508 530 508 530 0.98 19 19 0.9 1.2e+02 4.3 2.0 7 23 542 559 536 559 0.85
Sequence Information
- Coding Sequence
- ATGGTGAATCATAAACACACAGTCCACAAAGAAAGAAGAGATTTCGAATGCGATATTTGTAGTAAAAGATGTGCAACTAAAAGAAAAGTGTTGGAACACATTCGCCAAGTCCACGAAGGAACAAAAGATTTCGAATGCGAGCTTTGCGGTAAAAAATTTGGACGTAAGGTTAGTGTGCTGAAACACGAACGCACAATCcacggaggaaaaaaagatttcgaatGCGATATTTGCGGTAAAACATTTGGACAAAGCAGTCACATgctgaaacataaaaatgcagtccacgaaggaagaaaagatttcGAATGCGATGTTTGTGGTAAAAGTTCAGGATCGAAACAGCAAATGCTACGGCACATACTCGCAGTCCACGaacgaaaaaaagatttcaaatgCGATCTTTGCGGTAAAAGATTTGGACAAAGCGCTCACTTGCTGAACCATAAAAATGCAGTCcacgaaggaagaaaagattttGCATGCGATATTTGCGGTAAAAGATTTGGATGGAAACAGCAAATTCCAACACACAAACGCATAGTCCACGAAGGAACAAAAGATTTCGAATGCGATGTTTGCGGTAAAAGATTTGGACAAAGCAGTCACTTGCTGAATCATAAAAATGCAGTCCATGTAGGAAGTAAAGATTTCGAATGCGATGATTGCGGTAAAACATTCGGATCGAAACAGCAAATTCTGCGACACATAGGCACAGTCCACGAAGGAACAAAAGATTTCGAATGCGATATTTGCGGTAAAAGATTTGGACGTAAGAGTGGTCTGATGGAACACGAACGCTCAGTCcacgaaggaagaaaagatttcGAATGCGCTGTTTGCGGTAAAAGATTTGGACGTAAGGTTACTGTGCTGAAACACGAACGCACAATCCACGGAGGAAGAAAAGATTTCGAATGCGATATTTGCGGTAAAACATTTGGACAAAGCAGTCACATGCTGAGACATAAAAATGCAGTCcacgaaagaagaaaagatttcGAATGCGATATTTGCGGTAAAAGATCGGGATCGAAACAGCAAATGCTACGGCACATACTCGCAGTCCACGaacgaaaaaaagattttaaatgcgATCTTTGCGGTAAAAGATTTGGACAAAACGGTCACTTGCTGAACCATAAAAATGCAGTCcacgaaggaagaaaagattttGCATGCGATATTTGCGGTAAAAGATTTGGATGGAAACAGCAAATTCCAGCACACAAACGCACAGTCCACGAAGGAACAAAAGATTTCGAATGCGATGTTTGCGGTAAAAGATTTGGACAAAGCGGTCACTTGCTGAATCATAAAAATGCAGTCCATGTAGGAAGTAAAGATTTCGAATGCGATGTTTGCGGTAAAAGATTGCGATTGAAACAGCAAATTCTGAGACACATGCGCACAGTTcacgaaggaaaaaaagagttcGAATGCGATATTTGCGGTAAAAGATTTGGACGTAAGAGTGGTCTGATGGAACACGAACGCTCAGTCcacgaaggaagaaaagatttcGAATGCGATGTTTGCGGTAAAAGATTTGGACGGAAAGGTAATATGTTGACTCATAAACAAgttcacaaaagaaaaaataattttaaatgtgatATTTCTGGTAAACACTTTTCCCAGAAATCTCAGGAAACACGGCATAAGCGTTCTTTGCACGATGAAAAAACGCCAGATGGCCCTATTATTATTTCGGTTTCTTCAATTACCACAACACAATATGAATTAATTCAATCGACGAATTCAtaa
- Protein Sequence
- MVNHKHTVHKERRDFECDICSKRCATKRKVLEHIRQVHEGTKDFECELCGKKFGRKVSVLKHERTIHGGKKDFECDICGKTFGQSSHMLKHKNAVHEGRKDFECDVCGKSSGSKQQMLRHILAVHERKKDFKCDLCGKRFGQSAHLLNHKNAVHEGRKDFACDICGKRFGWKQQIPTHKRIVHEGTKDFECDVCGKRFGQSSHLLNHKNAVHVGSKDFECDDCGKTFGSKQQILRHIGTVHEGTKDFECDICGKRFGRKSGLMEHERSVHEGRKDFECAVCGKRFGRKVTVLKHERTIHGGRKDFECDICGKTFGQSSHMLRHKNAVHERRKDFECDICGKRSGSKQQMLRHILAVHERKKDFKCDLCGKRFGQNGHLLNHKNAVHEGRKDFACDICGKRFGWKQQIPAHKRTVHEGTKDFECDVCGKRFGQSGHLLNHKNAVHVGSKDFECDVCGKRLRLKQQILRHMRTVHEGKKEFECDICGKRFGRKSGLMEHERSVHEGRKDFECDVCGKRFGRKGNMLTHKQVHKRKNNFKCDISGKHFSQKSQETRHKRSLHDEKTPDGPIIISVSSITTTQYELIQSTNS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -