Basic Information

Insect: Ormyrus rosae
Gene Symbol: lola_2
Assembly: GCA_035047165.1
Location: JAWWML010029828.1:2722-15205[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.35 42 5.7 3.0 1 23 150 173 150 173 0.95

2 14 1.6 1.9e+02 3.6 0.5 2 12 177 187 177 190 0.90

3 14 2 2.4e+02 3.3 0.2 1 20 401 420 401 422 0.93

4 14 0.15 17 6.9 0.2 2 14 566 577 565 585 0.76

5 14 2.1 2.4e+02 3.3 0.6 3 23 596 617 595 617 0.96

6 14 0.58 68 5.1 4.6 1 12 627 638 627 641 0.87

7 14 0.044 5.1 8.6 3.5 1 21 699 719 699 720 0.95

8 14 3.5e-05 0.0041 18.3 2.6 1 23 728 751 728 751 0.98

9 14 0.02 2.4 9.6 1.3 1 21 800 820 800 821 0.95

10 14 0.0046 0.54 11.7 1.8 1 23 829 852 829 852 0.96

11 14 4.1e-05 0.0048 18.1 0.2 1 21 908 928 908 929 0.96

12 14 0.017 2.1 9.8 0.9 1 23 937 960 937 960 0.96

13 14 0.043 5 8.6 1.5 1 21 1021 1041 1021 1042 0.96

14 14 0.053 6.2 8.3 0.8 1 23 1050 1073 1050 1073 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.35	42	5.7	3.0	1	23	150	173	150	173	0.95
2	14	1.6	1.9e+02	3.6	0.5	2	12	177	187	177	190	0.90
3	14	2	2.4e+02	3.3	0.2	1	20	401	420	401	422	0.93
4	14	0.15	17	6.9	0.2	2	14	566	577	565	585	0.76
5	14	2.1	2.4e+02	3.3	0.6	3	23	596	617	595	617	0.96
6	14	0.58	68	5.1	4.6	1	12	627	638	627	641	0.87
7	14	0.044	5.1	8.6	3.5	1	21	699	719	699	720	0.95
8	14	3.5e-05	0.0041	18.3	2.6	1	23	728	751	728	751	0.98
9	14	0.02	2.4	9.6	1.3	1	21	800	820	800	821	0.95
10	14	0.0046	0.54	11.7	1.8	1	23	829	852	829	852	0.96
11	14	4.1e-05	0.0048	18.1	0.2	1	21	908	928	908	929	0.96
12	14	0.017	2.1	9.8	0.9	1	23	937	960	937	960	0.96
13	14	0.043	5	8.6	1.5	1	21	1021	1041	1021	1042	0.96
14	14	0.053	6.2	8.3	0.8	1	23	1050	1073	1050	1073	0.97

Sequence Information

Coding Sequence: ATGAACCTATTCAAATTGCTAACTACAATTACCAGAATTTCTGCAAaagcactttttaaaaaaattattgcgaaTGATGATGCTTCAACATCAAATTTGACGTATGTTAAAGAAGAAGTGGAGTTGGCAGCAGATTTTGATTCAAGTATAAGCATTGAAACTCCTGCGCAAACATCTACAACTGCGAAAGACACTACGCGAATAAATGTATCATGCTCTAAAGACGATAATACACctaaacttttcataaattctgATATGGTGAAACAAATAGATCTATTCTGCCCGACCTGCAAACAATCTTATGACATATCTACCGACTCGAGGACtcaaaattgcaaaagctGCATGCTCGGCTTAATCTACAGGTGCAAAATTTGCAAGAATGACTACTACGATTTGGAATACTGCTTGCGTCATCAGAGCAGAGGATGTCACCGGCTGAACTACTCCTGCAACAAATGCGAATTTGTGGGCAACACCAGATGCCAAATTGAACGACATATCAAATTCAACCACACCTTCGCAGTTTGCGAATACTGCAAGCAAGTATTTAAGCACGGCAaTAGCAACTCATCGACACTGTCTGCTGACGGACAATTTGAATTGACAAATTCAGATGTGATACTGAATGATACTGATATACTTAACAAAAGTGAGAATGGACCAGCAAAAGTATCTGTCGaagccAAGCATTCAAAGAAGCATCTGCATAATGTAGatcaggaaaaagaaaaacgattgCAAATTGAAGAATCATTAATCGataaAGATCCGCTCAATTTTCCGGAAACTATCGATGATGGAAGTCAATCCCCGGAATTGTCTATAGaaaaagatCCCCTCAGCATTGACAAAAGATCGTACGTCAAAGAAGAAATTGATATTGGGGGTGAATTCATGTATCTTGAGATGTCAAATGACTGCCCTTCAAGTGTCGAAACATTTTCTAATACTGAGGTCGATCCAATTGCGgagaataagaagaaaaaaatttcacgaggaaaaggaaaagaggATGTTCAGGACAAGGATGATGAAAGTTTCTCTGTTAGAATTCAAAATCgatttaaatatagtaatCAAAAATCAGtcTTGGAGAACCGAGCTCAAGTTTTCTGTCCAAAATGCAATATAGATTCAAAACGATTTTATGCTCGGAAAGGTGAACTGTGCAAAACCTGCGCAACTCCATTGCGTTTTCGATGCCTTGCTTGCAGCAAAGATTATCCTACACGCAGTGGGGTCAGATATCATGTTACCCAAGCCTGTCTAGTCAAACGTTACTCATACAATAagaagAACAAAAAATCCAAGAGTTCAATTGAGGAAGATCCACTTTTAACTGGTACCGAAAACGATGCTGAATCTTCTATGATAACGGAAAGTGACGGACCATCATTTATTGTAACAGAAAGTGATACATCCACGTCTATTGTGAATGAAACTGACGGTACCACTATTATCATTACCAAAGATGGTCTCAATTCTATTCTGCCAGAAAGTATTGTTCCAGATTGCATTACGCCACAAACTGAAGCTGCGGCGTCAATTCTACCGGAAAGTATTATACCCGACATTATTCTTAAGCctaaaaatgaagaatgtATCGCACCAGAAAATGAAGCTGCTGCTCCTGTGCAATCGAAAAATATAGCAATACCTTCCACCTCCGGAGAATGGAAACAATACATGAAGTGTCCCAGatgtgaaaagaaattttcgacGAATTTAATAAGAGCACACCTTCGACTTTGCAAAGAAAAGAAGCCCTTCTTCTTACTATGTTCACTGTGTCCTTTCAAAACGACAAAGACGGGCTCGTTTTTAGAACACGTAAAAATCACTCACGGAAGAACGACGGAAGAGCACAAATATCACAAATGTCCTAACTGCGATAGATGTTTCACTAAAACTCACAAAACAGGATCAGATTTTGTCCTTTGGTATCGAGTTCCCCAGATTCAAGCCACTTTTCCTTGTCTCTTTCCAGAGCGGCCCATCAGTTTTGTGCCTCTAAACTGGTCTCAGCATCACTCAAAGAACCTAACCCACCCGGTTCATCATCAGCTCGGCGAACAGCTCGGCCAGAAATTCCCGTGCACCGACTGCAGCAGCATTTTCAGCCGGAAGTGCAACCTGTACTACCACCGGAAGTACGAATGCGGCCAGCCGCCGCGGTTCCAATGTCCCTACTGTCAGTATCGCACCAGGCACCAGTCGAACGTTCGAGCGCACGTTCGAAGGATTCACACCGGCAAGGAGGTCTTTTTCATCGACGTTGGCCGACAGAACTTTGATTCCAacTACGAAATGTACGTATTTCCAAATGCACAAAATGAAGGGTCTTATCAAGAGAGAAGATCTCGATATCCGAAAAATGTGACAGAGAAGCCGTTCAGTTGCACCGACTGCTTAAGgaacttttattacattaaggATTTGCGCAAGCACGTAAAATACGAATGCAACAAGGAGCCGAGGTTCAAATGTCCGTACTGCGATTTGCGCTCGAAGCAGACGTCTTACATATATCGACATGTACGCGAAAAGCATAAACCAAACAAGGTTTACAGTCTCGATGTTCTCGTTGAGCCTAACGTTCTTTGGTATTACCCACCAGGAGGACGGCACGGAAGCTACATAAGGAAATCCCACCAACTTCACCGAAACAGAAGCAATCGATTTCGCGGCAACGAAAAGTCTTCGAGCACGGATCGATACCCTTGTCCAAATTGCAACAAGAGCTACGTGACGCGGAGCGCGATGAGAGCTCATTACAGATACGACTGCGGCAAACCACCGAGATTTCAGTGCCCCTATTGCGGGAAGCTCAACCGGAAGAAGTTCAACGTCCTGGACCACATCAAAAGAATACATACAAATAAGCCGGCTGTTTGCGTTACGAGATTTTATGACATTTTGTTTTGCATAGGCAGAACTAAGCTACGACGCATAAAACTGGCAGCAAAGAAAACCACGTCGACGAAGGGTCAAAAGCGTACTTACCGGCAGCGCGTGGCTTTCGACCACAGCTCGTTTAACGCTTCTACCGGGAGATATCACTGTCCGAAGTGCAACGGCGATTACAGCAGACGGGACTCGATGCTCGCTCATTACCGGCACGAGTGCGGCAAGGAGCCTCGATATCGGTGTCCGTACTGTTTGCTCGTCAGCAAGAAGACCTCGAACATTTATCAGCACGTCAGATACGTGCACGCTGATCAGCCGGTTAGCGTTGTGAAGCTGTATTAG
Protein Sequence: MNLFKLLTTITRISAKALFKKIIANDDASTSNLTYVKEEVELAADFDSSISIETPAQTSTTAKDTTRINVSCSKDDNTPKLFINSDMVKQIDLFCPTCKQSYDISTDSRTQNCKSCMLGLIYRCKICKNDYYDLEYCLRHQSRGCHRLNYSCNKCEFVGNTRCQIERHIKFNHTFAVCEYCKQVFKHGNSNSSTLSADGQFELTNSDVILNDTDILNKSENGPAKVSVEAKHSKKHLHNVDQEKEKRLQIEESLIDKDPLNFPETIDDGSQSPELSIEKDPLSIDKRSYVKEEIDIGGEFMYLEMSNDCPSSVETFSNTEVDPIAENKKKKISRGKGKEDVQDKDDESFSVRIQNRFKYSNQKSVLENRAQVFCPKCNIDSKRFYARKGELCKTCATPLRFRCLACSKDYPTRSGVRYHVTQACLVKRYSYNKKNKKSKSSIEEDPLLTGTENDAESSMITESDGPSFIVTESDTSTSIVNETDGTTIIITKDGLNSILPESIVPDCITPQTEAAASILPESIIPDIILKPKNEECIAPENEAAAPVQSKNIAIPSTSGEWKQYMKCPRCEKKFSTNLIRAHLRLCKEKKPFFLLCSLCPFKTTKTGSFLEHVKITHGRTTEEHKYHKCPNCDRCFTKTHKTGSDFVLWYRVPQIQATFPCLFPERPISFVPLNWSQHHSKNLTHPVHHQLGEQLGQKFPCTDCSSIFSRKCNLYYHRKYECGQPPRFQCPYCQYRTRHQSNVRAHVRRIHTGKEVFFIDVGRQNFDSNYEMYVFPNAQNEGSYQERRSRYPKNVTEKPFSCTDCLRNFYYIKDLRKHVKYECNKEPRFKCPYCDLRSKQTSYIYRHVREKHKPNKVYSLDVLVEPNVLWYYPPGGRHGSYIRKSHQLHRNRSNRFRGNEKSSSTDRYPCPNCNKSYVTRSAMRAHYRYDCGKPPRFQCPYCGKLNRKKFNVLDHIKRIHTNKPAVCVTRFYDILFCIGRTKLRRIKLAAKKTTSTKGQKRTYRQRVAFDHSSFNASTGRYHCPKCNGDYSRRDSMLAHYRHECGKEPRYRCPYCLLVSKKTSNIYQHVRYVHADQPVSVVKLY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -