Basic Information

Insect: Ormyrus rosae
Gene Symbol: mecom-b
Assembly: GCA_035047165.1
Location: JAWWML010000012.1:14153338-14177812[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00075 0.088 14.1 0.2 2 23 305 327 304 327 0.93

2 8 0.00012 0.014 16.6 0.3 1 23 363 390 363 391 0.91

3 8 6.7e-06 0.00078 20.6 2.6 1 23 397 419 397 419 0.95

4 8 3.2e-05 0.0037 18.5 5.0 1 23 425 447 425 447 0.98

5 8 0.14 17 7.0 1.6 2 21 455 474 454 475 0.94

6 8 3.5e-08 4.1e-06 27.8 1.7 1 23 887 909 887 909 0.99

7 8 5e-07 5.9e-05 24.1 1.7 1 23 915 938 915 938 0.97

8 8 1e-05 0.0012 20.0 3.5 1 23 944 966 944 966 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00075	0.088	14.1	0.2	2	23	305	327	304	327	0.93
2	8	0.00012	0.014	16.6	0.3	1	23	363	390	363	391	0.91
3	8	6.7e-06	0.00078	20.6	2.6	1	23	397	419	397	419	0.95
4	8	3.2e-05	0.0037	18.5	5.0	1	23	425	447	425	447	0.98
5	8	0.14	17	7.0	1.6	2	21	455	474	454	475	0.94
6	8	3.5e-08	4.1e-06	27.8	1.7	1	23	887	909	887	909	0.99
7	8	5e-07	5.9e-05	24.1	1.7	1	23	915	938	915	938	0.97
8	8	1e-05	0.0012	20.0	3.5	1	23	944	966	944	966	0.99

Sequence Information

Coding Sequence: ATGGAGTGTCTAGACCTGTCCAACCCGATGCTTGATTACAAGAGCAGCGGAAGCAGCGACGAGGGCGAGCCAGCAGGTGGGAGCGGAGGCTGCTTGGGCGGGGGCAGCGAGAGCGCGGCCGAGATGGAGGAGAACAGCTCCCTGCGCTCGTcgagcagcaacagcagcgccggcggcggcccgcACACCGACACCCCCAAGTCCTCCGCCGAGGCTCCCCACCTCTACAGGGAGTACCaccatcagcagcagcagcagcagcaggccaGGCAGGCCGCCCACCAGCCGCTCGACTACCGACCGCTCTTCGACGCCAGGATCGCGGAGCACTTCGACGACAAGAGCCTCATCTCACCGGCccttgccgccgccgccgccgcctacCGCAACGACTTTCATGCAGCCATCAAGCAGGAGGCAAACGACTCGAAGGAGCACCTGATGAGCGAGTGGAGCTCGGTACCGGACACGGTCAAGGTGAGCCTGTCATCGTCGGGCGCTCCCTGCATCCGGGCGCAGAAGGACATCGCGGAGGGCACGAGGATCGGGCCCTGCACCGGCAACTTATACATCGACTTCAAGTTACGGCAGCTCGCGAACGATTGCGAACCGTATTTAAAATCAGCCAAAGAAACGTTTGACGAATACAAGGACTGGATGAAGCTAATCGGACTCGCAGCGAATCCTGGCGAAGCGAATGTGCGAAAAGTCAAGCAAATAGATGGATacGTGCATTTGGAGGCCGTACGCAACATATCAGCCCGAGAGGAACTGCTCTCAAGTTACCCGGAAGCCCCGCTCCAACCACGGCGAGTGACCAACGAGGACGAGAACACGAGCGAATACGCTTCTCAGCACAGTGGAGCTTCTCACGCCGACGAGGACAAGGAGGATGAGGAATACGCCGAGACCAGGTGTACAGTCTGCGACAAGCCCTTCCAAGATATTGACGAGCTAAACAATCACCTGGTGTCGCGCCACAGCTACCCGGCCAGGGAACACGGCTGCTCGAGCTGCCCCAACGTCTACGCCTGGCGACCGCTGCTCGTCCGACACCGTGCCCTCGTACACGGCGACGTCCGCAAGTATCCCTGCGAGAACTGCTCAAAGCCGGTTGACCCACAGGTTTTCACGGACCCGTCCAATCTCCAGCGGCACATCCGCGCACATCACGTGGGCGCGCGCAGCCACGCCTGCACCGAGTGCGGCAAGACCTTCGCCACGAGCTCCGGCCTGAAGCAGCACACGCACATCCACAGCAGCGTCAAGCCCTTCACCTGCGACGTCTGCTTCAAGGCCTACACGCAGTTCTCGAACCTCTGCCGGCACAGGCGCATGCACGCCAAATGCCGCGTCCAGATCACCTGCAGAAAGTGCGGCGCCCAGTTCAGTAGCGTCACCTTCCTACATAAGCACAAGCGCTTCTGCGACTCGACCGGCCCCTCGACGAACGCCGCCTCCAGCATgccgcagccgcagccgcagccgATCCCCTTCGTCTACCCCCGGCAGCCGCTGCCTTACTACCCGACGAACCTCATCGGCCAGTACTCGGCCTCGCTGCTGCGCAGCGCCGACAACCTCCTGGGGCTGCAGCTGCTCATGCCGCCCAAGCCGATCTCTGACGAGTCGCTGGCCAGGCGCAGCGGCCAGCAGGCGGCCCGGCAGTGCGTCGAATCGCAGCTGCAGAACTACCTCCATCAACAGCTCGAGTACAACTGCTCCGAAAGCCCCTTGCGCGAGAGGTGCACCCCGGAGAGGAGCGTGGCCTCGATAAAGCAggagcaacagcagcaacagcagcagccggcCAGCAAGGTCTCGCCCTCAGCCGCCGAGGAGGCCACCTCGAGTCTGAGGCCGTCACCCGCGAGGCCGCCCCCGCTGCAGTCCGACGCCGAGGAGCTTGACAGCCCGAGGCAGCACAGGCGCAAGCGCAGCTATGACGAGGTGGATgatcggcagcagcagcagcagcagcagcagcaacagcaatcGGAGCAGCAAGCTTCGAGCTCGGAGCAGCCCCTGGATCTGCGCGTGCAGACGAAGCGCAGGAAGACCCAGGCAGCTCAACagcccagcagcagcagccaagACTCGACGGAGCGCGAGCCGGAGCCCGAGCTCGAGCACGAGTCCGAGCCCCCTCCGGAGCGAAAGAGAAGCGAGGAGCCGTCCCGAACCGCGACTCCTCAGGAGCGACATGCGCTCAGCCAGAGTCGCCCATCCAGCAGAGTCAGGAGCGAGCGCTCCGAGAGGGCCCCCTCGGAGAGTAAAGACTTGAGCAGCAGCAACGCCTTGCGAAACAATCTCCAGGCACCCCCAGCGGAAaCTTTGCCACACATGGCCTATCCCAGACCCATCcatcctctctttctcgagtCTGTGTACCGTAACTCCTCAAATGCCTTCCCCAGCTTTCCCGGACCCGGAGGCCCAGCCGACCACAGAATGCTCCAGCATCTGCCCTCTTTTGGACCGTCTCGCGGTCTTCCTTTTTTGGGCCCTCTAATGAACGGTCTCGGTGGACCCAGGCCCGGCGGCTACGACGTCTTGACTAGACCACCACTAGTCTTCCCAGGAGTGAAACCCATGCAAGATTCGGTGATGGCTCATCACCCGCAGACGCCGTTCGTCGGCAAAATCAAAGATCGCTACTCGTGCAAGTTCTGCGGCAAAAACTTCCCCAGATCGGCGAATCTCACGAGGCACTTGAGGACTCACACCGGCGAGCAGCCCTACAAGTGCAAGTACTGCGAACGTAGCTTTAGCATCTCCAGCAATCTTCAGCGCCACGTGCGCAACATCCACGACAAACAGAGGCCTTTCAAGTGCCCGATGTGCGAGCGCTGCTTTGGCCAGCAGACGAATCTCGACCGACACCTGAAGAAACACGAGGCCGACGACGGCAGCGGCGTTGTATCCGTCGCCGACTCGGCAGACAGCAGCAACGAAAACGAACGAGAAGAAACGTCGACGTACTTCGACGAGATCCGCTCTTTCATGGGCAAAGTCACCTACGGAGGTGACGCCTACGGCTTGGCTCAACATCACCCTGCCTACCTACCAAGCCGGCTCCGGGAAGTTCACGAAGCTCATGATCTGATGGACGGTGTTGTTGGAAAAAagtacgacgacgacgaggataGCGAGGACAGAGTGTCGCCACTGGAGCAGGCCGACAGGCTGTCACCGACTCAGTCTTCACCATCGCAGTACGATCTCAAGCTTAGCGGCAAGCGGGAACTGTTGAACAATAACACTGCAGAGCCGGTCATCGAGATCTCGACATAG
Protein Sequence: MECLDLSNPMLDYKSSGSSDEGEPAGGSGGCLGGGSESAAEMEENSSLRSSSSNSSAGGGPHTDTPKSSAEAPHLYREYHHQQQQQQQARQAAHQPLDYRPLFDARIAEHFDDKSLISPALAAAAAAYRNDFHAAIKQEANDSKEHLMSEWSSVPDTVKVSLSSSGAPCIRAQKDIAEGTRIGPCTGNLYIDFKLRQLANDCEPYLKSAKETFDEYKDWMKLIGLAANPGEANVRKVKQIDGYVHLEAVRNISAREELLSSYPEAPLQPRRVTNEDENTSEYASQHSGASHADEDKEDEEYAETRCTVCDKPFQDIDELNNHLVSRHSYPAREHGCSSCPNVYAWRPLLVRHRALVHGDVRKYPCENCSKPVDPQVFTDPSNLQRHIRAHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFTCDVCFKAYTQFSNLCRHRRMHAKCRVQITCRKCGAQFSSVTFLHKHKRFCDSTGPSTNAASSMPQPQPQPIPFVYPRQPLPYYPTNLIGQYSASLLRSADNLLGLQLLMPPKPISDESLARRSGQQAARQCVESQLQNYLHQQLEYNCSESPLRERCTPERSVASIKQEQQQQQQQPASKVSPSAAEEATSSLRPSPARPPPLQSDAEELDSPRQHRRKRSYDEVDDRQQQQQQQQQQQSEQQASSSEQPLDLRVQTKRRKTQAAQQPSSSSQDSTEREPEPELEHESEPPPERKRSEEPSRTATPQERHALSQSRPSSRVRSERSERAPSESKDLSSSNALRNNLQAPPAETLPHMAYPRPIHPLFLESVYRNSSNAFPSFPGPGGPADHRMLQHLPSFGPSRGLPFLGPLMNGLGGPRPGGYDVLTRPPLVFPGVKPMQDSVMAHHPQTPFVGKIKDRYSCKFCGKNFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPMCERCFGQQTNLDRHLKKHEADDGSGVVSVADSADSSNENEREETSTYFDEIRSFMGKVTYGGDAYGLAQHHPAYLPSRLREVHEAHDLMDGVVGKKYDDDEDSEDRVSPLEQADRLSPTQSSPSQYDLKLSGKRELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01112053; iTF_01110391; iTF_01113668;
90% Identity: iTF_01112053;
80% Identity: -