Olab004428.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ormyrus labotus
Gene Symbol
prdm10
Assembly
GCA_035582975.1
Location
JAWWEO010000009.1:29860345-29864499[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0017 0.18 13.0 6.5 1 23 598 620 598 620 0.92
2 8 3.3e-05 0.0034 18.4 2.1 1 23 628 650 628 650 0.99
3 8 8.7e-05 0.0092 17.1 4.8 1 23 685 707 685 708 0.96
4 8 0.025 2.6 9.3 3.3 1 23 713 735 713 735 0.97
5 8 9.7e-06 0.001 20.1 1.5 1 23 741 764 741 764 0.96
6 8 0.002 0.21 12.8 1.0 1 23 797 820 797 820 0.97
7 8 0.00015 0.016 16.3 2.4 1 23 842 865 842 865 0.97
8 8 0.0045 0.47 11.7 3.4 3 23 903 924 903 924 0.98

Sequence Information

Coding Sequence
ATGGACCAAGGGGGCCCTCTTGAGGGGGCCCCTGTCGTCATTGCTGACCCCATGGATATGACCATTATCGATAAGGTTTGCGCAGACACTAATTGGCCTGATGACAATATCGTATCATCGTCAACTTTTTGTGATAAtccaaagaaatttaataataagcttttatttatgacAgTTGAGTATATTGAAGACCCAAATAAGGATTTTGGTAGAATGTATCCTTCCTATGAGCAAGTTTCCTTTTCATCCAGGGCAAATTCACCATTGTCTGATTTTGATCGTGTCAGTCCACATGACCCTAATATGAGTTCAGCTGCGAGATATTCTCCAACTCCAGTTCCATTACCTTCATCACCTTTCCACAACTCTGTAGTTGTTCTCCAAGAAGATTCGGCACCACTTATATCAACATCAGAATCTGCAGTTAGGATCAACAATGAATACTCACCCCAACTTACCGATCAATCATCTACACCTAGTATGTCCCAAAGTGATAGTTCTGAAGATTTTACTGACAGTACAAGTGATGGATTAGTTACAAGTGTTGGAAATGAGCTTATGCTGATGCAAGgttCAAATGCAGAATTAGAAACTTCTTCTGCTCCATTGATACTGGCAGGAATTACAGGATCTGATTTAAATCTTGCAAGAGAATTATTTGTTATGCAAGAAGaacaaattaatgttattaattccataaaattaaatgcaagtTTGGATACTAATGTAGATCAAGTTACGGAAACTATTTTACCACATGAAATTGATGAAGAAACTAACGCACAAATATCTtcaatgaaaagttttaaaaaattatctgagcaacttgaaaaagtaactgactcagataaaaaaagtgttcATTGGTGTAAAAATCAAACCAATGAAGACAATAGCCTATGGTACGAAGACTGTGATAGTACTTGCACAGATGCAACAGATTGCACTTTGCACAGTGTATGCACCATTGCTGATCAACCAGTTCCTTCTAGAGCTGTTGCGACATTACCTGGCCTCTATCTATCGATTGAAAAACTTCCATCTGATACTTCTGATGGATCAACAGTATTTGGTGTTTTTGCAAAACGCAATATTCGTCGGCGGACTCAATTTGGTCCAATAGAAGGAATATTACATCCTTATGACGGATCTCCCATTGATGGATTACCCTTGTTGTTAGAAACTAGAGAAGAGAGCGAGTTCCTGCAAATTGATGTGTCAGATGAAaacTCTTCAAATTGGATGCGATTTGTACGACCCGCTCAAACTTATGAAGAgcaaaatttagtaatttctCAACAGAATGatggaataatatttttaacaactcGGAATATTATGCCTAATGAAGAATTAAAAGCTGGCCCAAGTCTTGAATATGGGAAACGTAGAAATTTAGCAGTGCTTGAagttaaacataaaaattctttagaTTCATCAAACGGAGAATTTTGCACTCAGTCTCATATAAAAGTAAGCCCATTTGAAATAGTTGATGAAGGGAGtcaaaataacttaataattgcTGAAGatgattttgaagtaaatCCTGAAAGATTACAAACAAAACGCAAAGCAGCTCATATTTCATTTCaaaaatatcttgaaattaatgaaGATGAAGAGGAAGATGAAGAAGATAATGATATAAGTCATTCAAAATTAGAATCAGATGAGAAAGTAAAAGAGAGTGCTCTGGATACTAAACTAGAGTTAATGAAACAAGAAATTACGCAATCCGATCAAGtggatattttagaaaaagtgaCAAACGTTGTTTCATCTAGTATCTACAAATGTACAATATgctcaaaacatttttcatcaaactACAAACTTCAGCAACACTGCCTGGTACATGATGTGAAAGATGACGATTCTTTTACATGCAATGTTTgcttaaaaagctttttaaataactcaTCATTAACACGACATTTAAAAACCCatcaaaAAGATAAGAAATCTATTGAGTGTGCAATATGTAGAGACGCATTTGGACGTATgactttaaaagatttttctgacACGCATCTAAATCAAGATGAAACATTTACCTGTCCTCACTGCCCGAAAACATTTACTAGTTATGCATTAACTCGTAAACATGCTAGATCACATCATCTTGATCGGAAACACGAATgtcaattttgtttaaaatgttttcctgCTGCAGATAAATTGAgaatgcatttattaaaacattctgATCGcagAGAATTCCAATGTGCTAACTGtggaaagcaatttaaaagaaaagataaactTAAAGATCATGTAACTCGCGTACACTATACCCAAAAGACTAACAAGGACcaaatttcaacaaataatCGTGCCAAAAAAGCAATTCCAAAGttaAATCAAGCAGATTGTGATCGTTTCGTTTACAAATGTCGTCGTTGCCAAGTGGGTTTCAAGCGAAGGGGGATGCTTGTAAATCACCTAGCTAAACGTCATCCAGATGTCCCTCCTGAAACTGTACCAGAGCTTAGTTTACCAATTTTGCGACAAACAAGAGATTACTATTGTCAATATTGTgagaaaGTTTATAAAAGTAGCAGTAAGCGAAAAGCGCACATTATGAAAAATCATCCGGGAGCAGCTTTGCCACCAAGCAATAGGAACAAGGATTTTGATATTCCTGGTTTACCTAATCCAACTTTTAGTCAGGCCGCTGGCAGTATTAAAACTGTTCCACAGGGTTGCCAATGGTGCCACAAACAATATGCTAGTAAAgcGAAACTCTTGCAGCATCAGCGTAAAAAGCATCCTAGTTTAATGGAACCTGCGGATCAGATTCCTCGCCCACGAAGCCGTCCACCGCAAAATCAAAATCAGCCGCCGACATCCACCTGCTCGAGCGcaaatgatattaatttaataaacgagcATAATGAAATTTGCGAGGATTCAAATGATCCAGAGTTCATGAAAGCGCGGATAATTCGAATTAACGGAACGGTCGGTGAGTCGTTGTCCGTCAACAATAGCTTTGAGTTGTTGAACCCGCAATTTGCTCGCGTGCGCGATATGCGTTGA
Protein Sequence
MDQGGPLEGAPVVIADPMDMTIIDKVCADTNWPDDNIVSSSTFCDNPKKFNNKLLFMTVEYIEDPNKDFGRMYPSYEQVSFSSRANSPLSDFDRVSPHDPNMSSAARYSPTPVPLPSSPFHNSVVVLQEDSAPLISTSESAVRINNEYSPQLTDQSSTPSMSQSDSSEDFTDSTSDGLVTSVGNELMLMQGSNAELETSSAPLILAGITGSDLNLARELFVMQEEQINVINSIKLNASLDTNVDQVTETILPHEIDEETNAQISSMKSFKKLSEQLEKVTDSDKKSVHWCKNQTNEDNSLWYEDCDSTCTDATDCTLHSVCTIADQPVPSRAVATLPGLYLSIEKLPSDTSDGSTVFGVFAKRNIRRRTQFGPIEGILHPYDGSPIDGLPLLLETREESEFLQIDVSDENSSNWMRFVRPAQTYEEQNLVISQQNDGIIFLTTRNIMPNEELKAGPSLEYGKRRNLAVLEVKHKNSLDSSNGEFCTQSHIKVSPFEIVDEGSQNNLIIAEDDFEVNPERLQTKRKAAHISFQKYLEINEDEEEDEEDNDISHSKLESDEKVKESALDTKLELMKQEITQSDQVDILEKVTNVVSSSIYKCTICSKHFSSNYKLQQHCLVHDVKDDDSFTCNVCLKSFLNNSSLTRHLKTHQKDKKSIECAICRDAFGRMTLKDFSDTHLNQDETFTCPHCPKTFTSYALTRKHARSHHLDRKHECQFCLKCFPAADKLRMHLLKHSDRREFQCANCGKQFKRKDKLKDHVTRVHYTQKTNKDQISTNNRAKKAIPKLNQADCDRFVYKCRRCQVGFKRRGMLVNHLAKRHPDVPPETVPELSLPILRQTRDYYCQYCEKVYKSSSKRKAHIMKNHPGAALPPSNRNKDFDIPGLPNPTFSQAAGSIKTVPQGCQWCHKQYASKAKLLQHQRKKHPSLMEPADQIPRPRSRPPQNQNQPPTSTCSSANDINLINEHNEICEDSNDPEFMKARIIRINGTVGESLSVNNSFELLNPQFARVRDMR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01112099;
90% Identity
iTF_01111267;
80% Identity
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