Basic Information

Insect: Orchestes rusci
Gene Symbol: ZEB2
Assembly: GCA_958502075.1
Location: OY293311.1:29570828-29582115[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 36 0.00016 0.026 16.6 1.8 1 23 4 26 4 27 0.95

2 36 1.2e-05 0.0019 20.1 1.8 1 23 61 83 61 83 0.98

3 36 0.00019 0.031 16.3 1.1 2 23 101 122 100 122 0.96

4 36 0.00022 0.035 16.1 4.0 1 23 128 152 128 152 0.97

5 36 0.00027 0.044 15.8 0.2 1 23 158 180 158 180 0.98

6 36 0.0011 0.18 13.9 1.0 1 23 186 209 186 209 0.98

7 36 5.6 9e+02 2.3 0.2 1 10 260 269 260 276 0.90

8 36 0.00067 0.11 14.6 2.2 2 23 289 311 289 311 0.96

9 36 0.42 67 5.8 0.0 3 23 319 339 318 339 0.96

10 36 0.0081 1.3 11.2 1.3 2 23 350 369 349 369 0.94

11 36 0.16 25 7.1 5.3 1 20 377 396 377 399 0.88

12 36 9.3e-06 0.0015 20.5 2.4 2 23 405 426 404 426 0.97

13 36 0.0056 0.9 11.7 1.5 1 23 434 456 434 456 0.98

14 36 0.73 1.2e+02 5.0 0.9 2 11 463 472 463 475 0.87

15 36 0.031 5 9.4 0.5 1 20 514 533 514 536 0.93

16 36 0.16 26 7.1 0.6 6 23 606 624 605 624 0.93

17 36 0.014 2.3 10.4 0.5 2 23 630 651 629 651 0.96

18 36 9.7e-05 0.016 17.3 0.7 2 23 685 706 685 706 0.98

19 36 3.3e-05 0.0054 18.7 0.4 1 23 712 734 712 734 0.98

20 36 0.0053 0.85 11.8 0.9 1 23 742 764 742 764 0.87

21 36 0.0075 1.2 11.3 0.9 1 21 770 790 770 791 0.91

22 36 1.9e-05 0.003 19.5 2.4 1 23 800 823 800 823 0.96

23 36 2e-05 0.0032 19.4 1.0 1 23 829 851 829 851 0.98

24 36 0.0037 0.6 12.3 0.2 2 23 858 880 857 880 0.91

25 36 0.00026 0.041 15.9 1.0 1 23 885 907 885 907 0.98

26 36 0.13 22 7.4 3.7 2 23 918 937 917 937 0.92

27 36 1.7e-06 0.00028 22.8 0.5 1 23 944 966 944 966 0.98

28 36 7.9e-06 0.0013 20.7 0.9 1 23 972 994 972 994 0.99

29 36 1.1e-06 0.00019 23.3 0.3 1 23 1000 1022 1000 1022 0.98

30 36 0.021 3.5 9.9 0.3 3 23 1030 1051 1028 1051 0.97

31 36 0.00023 0.037 16.1 1.8 3 21 1072 1090 1071 1093 0.90

32 36 0.00023 0.037 16.1 0.4 1 23 1099 1122 1099 1122 0.97

33 36 0.084 14 8.0 0.5 3 23 1127 1147 1126 1147 0.98

34 36 0.039 6.4 9.0 2.6 2 23 1174 1195 1173 1195 0.97

35 36 0.23 37 6.7 1.5 3 23 1206 1224 1205 1224 0.79

36 36 1.1 1.8e+02 4.4 1.4 2 17 1231 1246 1230 1248 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	36	0.00016	0.026	16.6	1.8	1	23	4	26	4	27	0.95
2	36	1.2e-05	0.0019	20.1	1.8	1	23	61	83	61	83	0.98
3	36	0.00019	0.031	16.3	1.1	2	23	101	122	100	122	0.96
4	36	0.00022	0.035	16.1	4.0	1	23	128	152	128	152	0.97
5	36	0.00027	0.044	15.8	0.2	1	23	158	180	158	180	0.98
6	36	0.0011	0.18	13.9	1.0	1	23	186	209	186	209	0.98
7	36	5.6	9e+02	2.3	0.2	1	10	260	269	260	276	0.90
8	36	0.00067	0.11	14.6	2.2	2	23	289	311	289	311	0.96
9	36	0.42	67	5.8	0.0	3	23	319	339	318	339	0.96
10	36	0.0081	1.3	11.2	1.3	2	23	350	369	349	369	0.94
11	36	0.16	25	7.1	5.3	1	20	377	396	377	399	0.88
12	36	9.3e-06	0.0015	20.5	2.4	2	23	405	426	404	426	0.97
13	36	0.0056	0.9	11.7	1.5	1	23	434	456	434	456	0.98
14	36	0.73	1.2e+02	5.0	0.9	2	11	463	472	463	475	0.87
15	36	0.031	5	9.4	0.5	1	20	514	533	514	536	0.93
16	36	0.16	26	7.1	0.6	6	23	606	624	605	624	0.93
17	36	0.014	2.3	10.4	0.5	2	23	630	651	629	651	0.96
18	36	9.7e-05	0.016	17.3	0.7	2	23	685	706	685	706	0.98
19	36	3.3e-05	0.0054	18.7	0.4	1	23	712	734	712	734	0.98
20	36	0.0053	0.85	11.8	0.9	1	23	742	764	742	764	0.87
21	36	0.0075	1.2	11.3	0.9	1	21	770	790	770	791	0.91
22	36	1.9e-05	0.003	19.5	2.4	1	23	800	823	800	823	0.96
23	36	2e-05	0.0032	19.4	1.0	1	23	829	851	829	851	0.98
24	36	0.0037	0.6	12.3	0.2	2	23	858	880	857	880	0.91
25	36	0.00026	0.041	15.9	1.0	1	23	885	907	885	907	0.98
26	36	0.13	22	7.4	3.7	2	23	918	937	917	937	0.92
27	36	1.7e-06	0.00028	22.8	0.5	1	23	944	966	944	966	0.98
28	36	7.9e-06	0.0013	20.7	0.9	1	23	972	994	972	994	0.99
29	36	1.1e-06	0.00019	23.3	0.3	1	23	1000	1022	1000	1022	0.98
30	36	0.021	3.5	9.9	0.3	3	23	1030	1051	1028	1051	0.97
31	36	0.00023	0.037	16.1	1.8	3	21	1072	1090	1071	1093	0.90
32	36	0.00023	0.037	16.1	0.4	1	23	1099	1122	1099	1122	0.97
33	36	0.084	14	8.0	0.5	3	23	1127	1147	1126	1147	0.98
34	36	0.039	6.4	9.0	2.6	2	23	1174	1195	1173	1195	0.97
35	36	0.23	37	6.7	1.5	3	23	1206	1224	1205	1224	0.79
36	36	1.1	1.8e+02	4.4	1.4	2	17	1231	1246	1230	1248	0.84

Sequence Information

Coding Sequence: ATGCGCAACTATAGCTGTCAAATCTGCGGCAAGGTGGTGCGCAATAAAAACTACTTCCAGCTCCATCTACAAGGCCACCACAAGCAGTGGAACTTCACTTGCAGCTTGTGTTGTAAAGGCTTTATTTACAAGCATCAGTATAAGTTTCACATTAAGGTCAAGCACAGTTCTACCGATAAATATGTTTGCCATAAGTGCGGCAATTCATTTGATTCTCCCGTTTATCTAACCAAGCACCTCCAACGACATGATATGGTCAAATCTGCAAAAACAGTACATCGATCTAACCGTCAAAACTTGATGTGCCACGTGTGCGGCCAAAATTTCCAGCAGAAGGGAGAATTAAAGCTGCATGTTATGAGGCATAACGGGGATAAACCTCACACGTGTACGTACGAGGGATGTGCCAAGAGTTTTGTGAGGAAACAACATTTGATGTTGCACATGCGCAGCCATACAGGGGAGAAGCCGTATGAGTGTGACATATGCGGCAACAGGTATACGCAGAAGCCCAGCCTAGTCATACATAAAAGGGGACATTTAGGAGAGAGGCCTTATCAGTGTGACTTGTGCCAAAGCAACTTTGCCTCCAAGCAGCGACTCAATGTGCACATGAAGAAGGTGCACAAGCTGGTCACTTTCCTGACTCGACATATCAACCAACATGGCAGGAACAATCGCCTGAAGCGTTGTGGTGCATGTTTGGAGTACTTCCCCACCAAACATGAAAAGCTGCAGCACATTTATGCCAGCCACTGTGTTAAGGTGGAGGATAAGTTCAAATGTCTCCACTGTGATAGGCAGTATGGAGAGCTGCACCTGAGCGTCACCCACTGTAAGGTCCACATTACTGAGGCCCTAGAGCGTTGCCCTTATTGCTCCAAAGGCTTTACCAAACTAAGTGTGTTGAGACATCACGTGAAAATTAAACATGAAGGGTTACAGCCTAAGATATGTGACATTTGCGCTGCGGTGTTGCAAGATGAAAAGGGCCTGGCGGCTCATATGAAACGGCACGGTGTTGCCAAAGCACTCCCTTTAGCGCAACGTTGTGACCTATGCAACAAAACCTTCAGCAATCTTAAAGGGCACATGAGGGTAACCCATAATGCCGCCCAAGGCAATAACTTTCAGTGTCAGCAGTGCGGGAAGTTCTTCAAGCACGAACGAGGTCTGACATTTCATTTAATGTGCCACAACAACCAAACGCTGGAGTGTcacttttgtgacaaaaaatttGTGACTAAGTCTTTACTTTTAGAGCACTTGAGGTCTCATCCGCAAAGTGGGGTGGAACCTTTCGAGTGTGAGTTCTGTCAGAGGAGGTTTGTGAGGAGGGTGGTGTTTGAGGAGCACCGCAACAGACATTTGGGGTTGTTGAGGGCGGAGTGTGACCAGTGCGGCAAGTGTTTTGCTGAACCAGCAGTACCAGCGTATAGTATTTTATTCGACGAGTGGGAAATGggggatattactcacgaggatgtGGAGGAAGTCATTAAAATCGAACTGGTAGACGATGGAGATGACATCAAATCCTACACCTGCTACGTGTGCTTTGCAGTTTTTGCAACCTGTACAGAACTCACAGACCACATCCCAGTCCACCCCAATCAACTCCAGCCGAAAGTGTGCAAAATTTGCGATACCACCTCCGAAAATGGTGCTTCTCATGCAGAACACCTCTTTAGCATTCATTTTGACAAGGTAGAAACCGGCGTCCGTTGTGTCATCTGCCTCAAAACACTAGCCTCAATAAAAGAGGGCCTGGCCCATTATCGCAtgcacaaaaacaaaaagtacgCGTGCATCTGCTGCAGCAAAATCTACAACAGAAAGTACCAACTGATGTCCCACATTGAAGGGTTCCACAATGAAAAACGACTCAAGTGCCGCATCTGCAGTGTCACCTTGCAGGACAAATCCAGCCTGATGGCCCACTTGACCAGGCATGGTTCCGCCCAGCCTTTGCCCAGACGATGTAGCAAGTGCTTGAAGTTTACCAGGAATATAAAGAGGCACTACTACGACTGTACTGGCACCAACAAGCCTCAATGTCACCTTTGTGGCAAGGTTTACGCCACACAACAAGGGTTGGGTTTGCATATGAAAAGCCACACAGGGGAAGTACCCTTTGTTTGTGAGTTTTGCGGAAAAGGGTTCGTGCTTAACTCCTTCCTGACTATACACTTGAGGTCGCATCCGGAGAGTGGGGTGGAACCGTTCAAATGCGACTATTGCGGCCAGAAGTTCAGCAGGAGAAATATATGGTTGAGTCATGTTAATTTGCATACTGGGGTTCAACCTTATGAGTGTATTATGTGTCCTAAGAAATTTTCTAGCAAAAAGTCCTTGTCCAACCATAAGCTTAAACTCAAAAATCCACCCCTAAAGCCCTTCTGTTGTTCTTCCTGTCCAATCAGCTTCAAAAGCAGCTCGTCCCTCAACCGCCACATTCGGCAAATCCACGAGCAAACTGAAAAATACGCATGCGCTGATTGTGACAAGACCTTCAACTCCAAAACGAACTACGTCATTCATACCAAACGTCACTTGTCACAGTTTGTGATCAGTTGTGAGTTGTGCAAGGAGGGGTTTGTGACCAAGGCTGAGTACCGCAGGCACTTGGATGCCAAGCACAATCAGAATGAGTATGTTTGTGATGTTTGCGGCAAGAGTATTTCTAGTGAGAGGCATATGAGAGACCATAAGAGGATACATGAGAGTGACTACGAGGAGAGGTACTTTCAACAGTGTACCATTTGTAATAGGCGGTTCAGGCATCTGAAGAGGCACATCAAAGAATCCCACCAAGTGGATGGTACCAACTACATCTGTCCCACCTGCGGTAGAACCTTCAACAGGGAGAATAGCTTCAAGGTCCACATGATGATCCATAACGGGCTACGCCCTTACAAGTGTGACGTCTGCGCCAAGGAGTTCTACTCCAAGCAGTACCTGACGGTGCACATGCGCATTCACACCGGGGAGAAACCTTTTGAGTGCAGTGTGTGTGGCAAAAGATTCTCCCAGAAGCCTCCTTTAAATATACATATGAGGTTGCACAGTGGGGAGAGGCCTTATGGCTGTGATGTGTGTGTGGAGAAGTTTGTTTCTAGGCAAAAGTTGAATTTGCACAAGAGAAGTGCCCATCAGATTGTTAGCTCCCAAGAACGAATCGTGATTGAATACGTAGAAGACGATGACCACGGCTGCCACCTTTGCGGCAGAAGCTTCCGCAGAAAAATCGATCTGAACAAACACTTTGCCTTTGTCCATTTCAACACGCAATCCTATCCATGCAACATATGCGGGGAATCCTTCGACAAGAGATACCTAGCAGAACGCCACAAGAAATCCGACCACAAGCCCATTTTGTGTGTGGTCTGCTTCAAGACCTTCATGGGAGAAACCAGACTCAAAGCCCACGTCAAAACACACGAAACGGACGAAAATCAGACCAAAAACCTCATGCTTAAGTCAACTTTGCCCAAAGGAATCCCGATGAAAATGGCATTGAAGTGCCAGATTTGCAACGATAGGTTCCACAGCGTGGAGACGTTTGAGAAACACATCAAAACTCATGAGTTCTTAATGGATGACCTCAAAGAAATTTGTAATATTTGTAATAAGAAGTTTAAGAATGTCAAGTCCCACATGCTCAAAATGCATGTGCCGCAGGAGCCTTGCATGTGCGACCGCTGCGGCCAGACGTTCTTCAACCGCAAAGGGCTTGATGGGCACCCCTGTActgaataa
Protein Sequence: MRNYSCQICGKVVRNKNYFQLHLQGHHKQWNFTCSLCCKGFIYKHQYKFHIKVKHSSTDKYVCHKCGNSFDSPVYLTKHLQRHDMVKSAKTVHRSNRQNLMCHVCGQNFQQKGELKLHVMRHNGDKPHTCTYEGCAKSFVRKQHLMLHMRSHTGEKPYECDICGNRYTQKPSLVIHKRGHLGERPYQCDLCQSNFASKQRLNVHMKKVHKLVTFLTRHINQHGRNNRLKRCGACLEYFPTKHEKLQHIYASHCVKVEDKFKCLHCDRQYGELHLSVTHCKVHITEALERCPYCSKGFTKLSVLRHHVKIKHEGLQPKICDICAAVLQDEKGLAAHMKRHGVAKALPLAQRCDLCNKTFSNLKGHMRVTHNAAQGNNFQCQQCGKFFKHERGLTFHLMCHNNQTLECHFCDKKFVTKSLLLEHLRSHPQSGVEPFECEFCQRRFVRRVVFEEHRNRHLGLLRAECDQCGKCFAEPAVPAYSILFDEWEMGDITHEDVEEVIKIELVDDGDDIKSYTCYVCFAVFATCTELTDHIPVHPNQLQPKVCKICDTTSENGASHAEHLFSIHFDKVETGVRCVICLKTLASIKEGLAHYRMHKNKKYACICCSKIYNRKYQLMSHIEGFHNEKRLKCRICSVTLQDKSSLMAHLTRHGSAQPLPRRCSKCLKFTRNIKRHYYDCTGTNKPQCHLCGKVYATQQGLGLHMKSHTGEVPFVCEFCGKGFVLNSFLTIHLRSHPESGVEPFKCDYCGQKFSRRNIWLSHVNLHTGVQPYECIMCPKKFSSKKSLSNHKLKLKNPPLKPFCCSSCPISFKSSSSLNRHIRQIHEQTEKYACADCDKTFNSKTNYVIHTKRHLSQFVISCELCKEGFVTKAEYRRHLDAKHNQNEYVCDVCGKSISSERHMRDHKRIHESDYEERYFQQCTICNRRFRHLKRHIKESHQVDGTNYICPTCGRTFNRENSFKVHMMIHNGLRPYKCDVCAKEFYSKQYLTVHMRIHTGEKPFECSVCGKRFSQKPPLNIHMRLHSGERPYGCDVCVEKFVSRQKLNLHKRSAHQIVSSQERIVIEYVEDDDHGCHLCGRSFRRKIDLNKHFAFVHFNTQSYPCNICGESFDKRYLAERHKKSDHKPILCVVCFKTFMGETRLKAHVKTHETDENQTKNLMLKSTLPKGIPMKMALKCQICNDRFHSVETFEKHIKTHEFLMDDLKEICNICNKKFKNVKSHMLKMHVPQEPCMCDRCGQTFFNRKGLDGHPCTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -