Basic Information

Gene Symbol
RREB1
Assembly
GCA_963932345.1
Location
OZ010723.1:8617473-8623482[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00079 0.07 13.8 0.0 1 23 16 38 16 38 0.98
2 16 0.00018 0.016 15.8 0.3 1 23 52 74 52 74 0.98
3 16 6.4e-07 5.7e-05 23.5 2.8 1 23 80 103 80 104 0.97
4 16 0.025 2.2 9.1 0.4 1 23 210 233 210 234 0.93
5 16 3.9 3.5e+02 2.2 2.8 2 23 240 262 240 262 0.91
6 16 1.4 1.2e+02 3.6 0.3 1 19 320 338 320 340 0.89
7 16 0.007 0.62 10.8 0.1 1 23 459 481 459 481 0.97
8 16 6.1e-05 0.0055 17.3 0.3 1 23 490 512 490 512 0.98
9 16 0.0054 0.48 11.2 3.1 1 23 518 541 518 541 0.97
10 16 0.00048 0.043 14.5 3.0 1 23 984 1007 984 1007 0.97
11 16 0.00069 0.062 14.0 0.1 3 23 1320 1340 1318 1340 0.97
12 16 0.96 86 4.1 6.5 1 23 1346 1369 1346 1369 0.97
13 16 0.019 1.7 9.4 1.8 1 23 1433 1457 1433 1457 0.95
14 16 0.57 51 4.8 3.1 1 23 1602 1625 1602 1625 0.96
15 16 0.012 1.1 10.1 0.4 2 23 1679 1700 1678 1700 0.94
16 16 1.4 1.2e+02 3.6 8.2 1 23 1706 1728 1706 1728 0.98

Sequence Information

Coding Sequence
atgtatttttttatgcagACATCGGATCACCAGGACACCACATCGTATCCCTGTCCAGCCTGTCCAATAGTGGTAACGACGTCGCGCGATTTGACGAATCACCTACGGGGCCACAATTCACCCCGCAGTACCGATTACAGCGGCGAGGACGATTATTCCTGCGGGGTTTGTCACAAGGTACTAAGCTCAGCGAGTTCCCTGGACCGTCACGTACTCGTGCACTCGGGTGAACGGCCGTTCAAGTGCAAATACTGCGACATGGCGTTCACGACGAACGGGAACATGAACCGTCATTTGAGGACGGCCCATCACGGCGCGTCACCGCGCGACAACAGCGGCTACACGGATTCAGAGGGTAGCAGCGATTCCGAAAAGTCAGGTACCAAGAGACGTCATCATGCCTCGATCGAGCAAGAATACAACAACAATGAGATCGGCAAGAGCGGTACTACCGATATCTTCAATCAGCTCGAGTCATCGTCACCCACGAGATTTATGGCGAAGCGAAAGCGTACCGAGATCAACGAGGACACGGAAAATCCCGCGAGAAAGCACAAAATAATGTTGGGCAACTCGCGTACCGAGTTACAAAACGGCGAGATGAGAAACGACTCGCGTACGGTCGTTCACAATTGTCCAGTCTGCGGTAGGCTGGACTTCGCGACAAGCGCCCTCCTCGAGGCACATCTCGAGCGTCATCATCCGGAATTCCCGGCAAAGTGCGATCCCTGCAATCTCTCGTTCAAGAATCATCGCGTCCTCAATCTTCACAAATACATGAAGCACATAGACGGCGAGAACAGCTCGATCGGTAACAACGGCCGTAATTTGCGGAATTCGGTTGTTGGCTTCAACGATTTGACTTTCGTTGATTTCTCGTCGGGTAAGTTTCCGGCTATAGCACGAGCCGTCTGCGAGCAATCGCTTCATCGTCCTGCGTCCGGTGAGATCGCGAGATTCCAGTGTGACAAGTGTCTCCGAGCGTTTCCATGTCGTTCGGCCCTCGACGCCCACGAGATGGACTGCGGCACGAGCAGCCAGACGTCCGCGTGCTGCTTGGACGACCGTTCCTCCCGGCGGGATGACTTCTTCGCGGGTTTGGATCTCCAGAACAGAGCTGCACTCACCGAGGCCAAGGAGGGCAAGGATCTCGCTGACATACAGAGCATAATATCAGTGACTTCCGGCCCGATATTGCAAAGTTTCCCACGTTCGGATGCTAGCACACCGGAGCATCACAGGATGAAGGCTAACGCGAGTATGGCGGGTTCCTCAGGCTCGTCGGGTACGCCATCCTCGTCTGACTACCATCAGGAGGAGGAGGCCCAGGATGCGTTCGCCGCAGAGTTTCGTCGTATGAAGCTGAAGGGTGAATTCCCTTGTCGCTTGTGCGACGCCGTTTTCCCGAACCTTCGTGCCCTCAAAGGGCACAACCGTTCGCACATGGGTGTGGGCCCGGGTATGCCATATCCTTGCAACATGTGCCCCTACACGAGCAACGACAAGGGCACCCTCGTGCGCCATCTTCGATCGCACAACGGCGATCGTCCATTCGAGTGCTCGCTGTGCAACTTCGCCTTCACGACCAAGGCCAACTGCGAAAGGCACGTGAGAAATCGCCACGGCAAAGTCTCGCGGGAGGAGATCAAGAGCGTCATAATATATCATCCGAGCGAGGACAGCACCAACGATTCGGGCTCCCTCGACCGGTCGGATTCGCGTCGCGAGGACGCCCGGAAGTCTCTTGTTTATCCACCAAGCACCGCAATTAGCGAGAAGGACGACAGCTCCCAACGTCGCAAAGACTTTTATCTGGGCCTACAATTTGGCAACAAGCAGAGCACACCAAGCAGTGTCGTGTCCGACGAGCCACCTCACTCCCTGCGATCTCTTCACTACGACAAGTCTGACGCTTTCCCAAGGACGCCCACTCGCGGCGGTTACACGCGAGAATCGAGCCACGGAGCTTTGGAAGACGAGGtggaggacgacgacgaggacgattaCGATGATTACGATTACGAGGAGAACGAGAACGATTACGCGTTGGCCAAGTCAGAAAACAGCGGGAAGATCGGCTACAACGTTAATTCGAGATCTTCGGAGGACGACGGTGCTCTAGTCAGCGATACCAAAATGGCGGTACACCAAAGAGTTCAAGCTAGTCCGATAGACCTGAAGAAACAGAGCGCGAGGGCCGTGACCGCTTCGACCGGAAGTCCGAACGGTGACGACACCGTATTGGAAGCTACCACATTCGCGACTGGTGAAGACGCGCCCCTCGATCTCTCCATGGACGTTCTCGATCTCAGCAAAAAGTCAAGCGGCAACAACGCCAACCGAGACGTTTCATCGTCATCGCCCGTCGCAACTGCCATTCCTGTTAACGAGACTGAATTCGGTCGCAATCAGAAGGACTTTTACGATGCTACGAATCAATTTCTGCTGACACAGGCATTGCTGAAGGCCGGACAAGCCGGCAATCCAGCGACCTCTTTGGAGGCCCTCTACGCGAACGCTCACATGATCTACAGGAACTTCGGTGGCTTCTCAGCAGCTGGTGTTGGGCCTGGTATTTTGCCCCCCTATCTCTTCAATCCCCACATGTTCGGACAAGACTTCGCGATCAAGGACCGTCTGCAAAAGGAACTGCTACGCGGATTGCAACTTACCAGCGGCGGCAATATCGTCGAGCCGTCGGTCGGCAATACCGCTTTCACCGGTGCCTATCCACCCGCCAGAGAAGCGACGATCCCAAGAGCCGAGCAGCCAAACGATTACGGCAAACTCGCTAGCTCAAAACTACCACCAAAAATTGTCACCAGCACGTCGTCGATCAGAGAGCCAAAAGTCAGTAGTCCGCAATCCTCGAATTCCGTGAAAATGGTCATAAAAAATGGTGTTCTGATGCCGAAGCAGAAGCAACGAAGATACAGAACCGAGAGGCCCTTCACCTGCGAGCATTGCTCCGCCAGATTTACCCTTCGCAGCAACATGGAGAGGCACATTAAACAACAGCATCCACAACACTGGAGCCAAAGACCACGCGGTGGTCACTCCACAAGAGGACGTCCACCAGCGAATCCGCCCAGTCTCGTCGTGCCAACCGGCAACAATCACACCGTCACTCATTCGCTCTCCCAGCCATCCTGCAATACGTTACCGAAAATTGCCACATCCGGTGGATCATCGAACTACGAGAAACACTCTATTTCCGATCAGGTGAAATACGCGATACTTGCGCAGCAGTTAAAAGGCAGTAAAATCGAGGAGAACGACACCGAGGAGGAGTTGATCATCGACGAGAGCGCCCAAGAGAGCAAAGAGGTCGATGGCGAGGCTCGTACTACGACCAGTCTTCTCCGAGGGAAGCTCGAGGGAACGAGCACGTCCTACAAAGACACGAGATCGGATCAGCAAAGAAACAAAGCCCCGGAAGTTTTGAGGAGGGAATCACCGAGGTGCGAGGAAGGAACGAAACGGATGGAACGGACAACCAAGGAACCGATGGCCGAAGATTGCCGCAAAGTCGTTGTGAAGACAGAGCCCAAAGAGGAGGAGGATCAGGACGATAAAGCGATCGTAGATGGCGACCGAAAGGACGAGGCTCGTACACCGAGTCAACCGGGTCTTCCGGAAACGACCACCAAAGTCGAGCAATCGACGTCCCGCGATTGCCCAACGATCGAGAGAAGCGAGGACCTCGCGAGTGTTTCCGAGCTGTTGGACAACGCGTCACAGCAGTATCAACAATTTCAACCGCAGTACATGAGCGACGAGGAGGGTCTAGTTGCCTCGACAAGCGACTGCAACAATTCCGGTAGTGACGAAAAATCGGATTCCGTGAATTCGGCAAACTCGACAAATTCCCAAACGTCCTCGAagcgaaagaagaagaaaaagaagaagatgaagaagaagaagtcggCTTATTCGATGGCGCCTAATCGTGTTATATGTCCGTACTGCGAGAGACCGTTTCCCTGGACTTCGTCTCTCAGACGACACATCCTCACGCACACGGGACAAAAGCCCTACCAATGTATGCACTGCTCGTTGCTATTCACCACAAAGTCCAATTGCGATCGTCACTTGTTGAGAAAACACAAGAACAACGCCAACAAGATACGCCGCTTGAGGAATTCATCGTCACCAGAGGCACTAGAACAACCCTCCAACAACAACGACActagcagcaacaacaacaacatcagcagcagcaacaacaacaacaacaacaataacaacaacagcTCGAGCAGCGCTTTCGCGATGAGGAACGTGCCCGAGAGACCGTACAAATGTAACCTCTGTCCGAGCTCAACCTTTTCAACTTTGGGCAATCTGAAGAAGCACAAATCCTCGAAACACTCGAGGAATCCCGGTGTGAAATCGCGGGCAGAGTCGCCGGTAACGAGCGAGCCGCGTAACAGTCCGATCACCACGTCCAACAAGCAAAACGACAACAGCGGCTACGAGAGTCAATCCTCCGGTGTCTCGGAGAACATGGATCACATCGATGCCCTGGAGAACTCAGAGAACGCTCGCTCGAATCTTGCCTCGAACGCTGACGAGCCAGCGGCCGATGCTGAGATCGTCGAGAGCCGTCAACCATCCACAGATCCGGTGGCAAACCGGACGCGGGACAATTACGAAAGTATGGACTGCACCGACCCACCGGATAATTCATCGGACAATCAGATGCCAAAGAGTCACGAGTCGGCGAATCCAACGATGACGACGGAGGCCGCCAAGTCGCGGAGATTGTCACCGAGAGCGTCACCCGGACCTACCGACGCACCGTTCAAATGTCATCTTTGCGACAGCGGTTTCTCCGAGCGCCAGGATTGCCTGGAACACATAAGAATCAATCACACGAGATCTTACGAGGTTCTCGTGGCTAAGGGTGCTCTGGACATGGATATCGAAACTCCGgaggagcagcagcagcagccacCAAACGCATCCACCCTCCACACGAGCGACGGCGAAGAGAAACGCGGCAGATTTCCGGACTACAGCAACAGAAAGGTTGTCTGCGCATTCTGCATGCGTCGTTTCTGGTCGGCGGAGGATCTTCGCCGTCACATGAGGACCCACACCGGCGAGCGACCGTTCTCTTGCGACATATGCTGTCGACGTTTCACCCTCAAGCACAGCATGCTACGTCATCGAAAGAAACACGAGTCGGTTGATTCCATGATGTACGTGGGTACGAGCGGTGACGAGGAATCGGCCCCATCCCAGCCACCAACGATCACACCACGCAGCCAGCAACAACCGCAGCAGAATCCAGGACTCGTAAGCACTACTACGAGTTGCGAGTCGGGGCTGCAGGAGAGAATGTCACTGGCAACTGTGGTGACTGTGGCGACTGGCGATGCTGCGTCGAGTGGCCTCGCGCGCTTCAATCCTTACGAAAAATTGGCCACTTTCACGAGCAAAATGACAAACGCCCAGCAGAACTTCAACGCCACTGAGGGCACCACGGACACGGAAAACGATCTCATCTCGAATCTTCTCGGCATCCGGGACAAGAGCATCATCGACAAAGTCTTGCAAGCGTCGGCTGATGACGCTGCGAAACTACTCGGCGTCAACAGACATCACGATTGA
Protein Sequence
MYFFMQTSDHQDTTSYPCPACPIVVTTSRDLTNHLRGHNSPRSTDYSGEDDYSCGVCHKVLSSASSLDRHVLVHSGERPFKCKYCDMAFTTNGNMNRHLRTAHHGASPRDNSGYTDSEGSSDSEKSGTKRRHHASIEQEYNNNEIGKSGTTDIFNQLESSSPTRFMAKRKRTEINEDTENPARKHKIMLGNSRTELQNGEMRNDSRTVVHNCPVCGRLDFATSALLEAHLERHHPEFPAKCDPCNLSFKNHRVLNLHKYMKHIDGENSSIGNNGRNLRNSVVGFNDLTFVDFSSGKFPAIARAVCEQSLHRPASGEIARFQCDKCLRAFPCRSALDAHEMDCGTSSQTSACCLDDRSSRRDDFFAGLDLQNRAALTEAKEGKDLADIQSIISVTSGPILQSFPRSDASTPEHHRMKANASMAGSSGSSGTPSSSDYHQEEEAQDAFAAEFRRMKLKGEFPCRLCDAVFPNLRALKGHNRSHMGVGPGMPYPCNMCPYTSNDKGTLVRHLRSHNGDRPFECSLCNFAFTTKANCERHVRNRHGKVSREEIKSVIIYHPSEDSTNDSGSLDRSDSRREDARKSLVYPPSTAISEKDDSSQRRKDFYLGLQFGNKQSTPSSVVSDEPPHSLRSLHYDKSDAFPRTPTRGGYTRESSHGALEDEVEDDDEDDYDDYDYEENENDYALAKSENSGKIGYNVNSRSSEDDGALVSDTKMAVHQRVQASPIDLKKQSARAVTASTGSPNGDDTVLEATTFATGEDAPLDLSMDVLDLSKKSSGNNANRDVSSSSPVATAIPVNETEFGRNQKDFYDATNQFLLTQALLKAGQAGNPATSLEALYANAHMIYRNFGGFSAAGVGPGILPPYLFNPHMFGQDFAIKDRLQKELLRGLQLTSGGNIVEPSVGNTAFTGAYPPAREATIPRAEQPNDYGKLASSKLPPKIVTSTSSIREPKVSSPQSSNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPANPPSLVVPTGNNHTVTHSLSQPSCNTLPKIATSGGSSNYEKHSISDQVKYAILAQQLKGSKIEENDTEEELIIDESAQESKEVDGEARTTTSLLRGKLEGTSTSYKDTRSDQQRNKAPEVLRRESPRCEEGTKRMERTTKEPMAEDCRKVVVKTEPKEEEDQDDKAIVDGDRKDEARTPSQPGLPETTTKVEQSTSRDCPTIERSEDLASVSELLDNASQQYQQFQPQYMSDEEGLVASTSDCNNSGSDEKSDSVNSANSTNSQTSSKRKKKKKKKMKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCMHCSLLFTTKSNCDRHLLRKHKNNANKIRRLRNSSSPEALEQPSNNNDTSSNNNNISSSNNNNNNNNNNSSSSAFAMRNVPERPYKCNLCPSSTFSTLGNLKKHKSSKHSRNPGVKSRAESPVTSEPRNSPITTSNKQNDNSGYESQSSGVSENMDHIDALENSENARSNLASNADEPAADAEIVESRQPSTDPVANRTRDNYESMDCTDPPDNSSDNQMPKSHESANPTMTTEAAKSRRLSPRASPGPTDAPFKCHLCDSGFSERQDCLEHIRINHTRSYEVLVAKGALDMDIETPEEQQQQPPNASTLHTSDGEEKRGRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKHESVDSMMYVGTSGDEESAPSQPPTITPRSQQQPQQNPGLVSTTTSCESGLQERMSLATVVTVATGDAASSGLARFNPYEKLATFTSKMTNAQQNFNATEGTTDTENDLISNLLGIRDKSIIDKVLQASADDAAKLLGVNRHHD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01100840;
90% Identity
-
80% Identity
-