Basic Information

Gene Symbol
-
Assembly
GCA_963210295.1
Location
OY723395.1:18204747-18219406[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00045 0.058 14.7 4.1 1 23 221 243 221 243 0.97
2 11 1.4e-05 0.0018 19.5 1.5 1 23 249 271 249 271 0.98
3 11 0.0035 0.46 11.9 3.8 1 23 277 300 277 300 0.95
4 11 0.014 1.8 10.0 5.2 1 21 306 326 306 328 0.95
5 11 0.00014 0.018 16.3 1.9 1 23 334 356 334 356 0.99
6 11 9e-06 0.0012 20.0 0.3 1 23 362 384 362 384 0.98
7 11 0.0066 0.86 11.0 2.2 1 23 392 415 392 415 0.96
8 11 3.7e-05 0.0049 18.1 2.6 2 23 422 443 421 443 0.97
9 11 0.00014 0.018 16.3 0.3 1 23 449 471 449 471 0.99
10 11 0.0031 0.4 12.1 7.1 1 19 477 495 477 500 0.91
11 11 1.2e-07 1.6e-05 25.9 1.3 1 23 514 536 514 536 0.98

Sequence Information

Coding Sequence
ATGTCGACCAACGTAGCTACCATCAAGCTGGAGGAGGGACAGGAGTCGGTCACCGAGATACAAACCTACCTGGAAACGTTCAACAAGGAGATCGAGGGAGGCCAAGGCGAACAATTGCAACATGTTCAACTGCAGCAAGTGGAGGGCCTGTCGGGCGGCGAGGAGGGCGGAACATACTTTGTGGATCAGTCCGGTCAGTACTACTATCAGGCGAGCGGCGACGACGCCCCTGTAATGACTCAGGTACAGATCCAAGAGATAGACGACGGCGACGGCCACGAGGGCGAAGTCTCGGAGGAGCAATACCACGAGATCGAAGAACTGGACACCGTCGACGGCGATGAGGATGGTCACAACACCGAGAACAATCGGGTAGTGTTGAACTCCGGCGACGCTTATCAGACGGTGACGATAGTGCCGTCGGACACGAATCCGGGCGAGGTGAGCTACGTGTTGATCGTCCAGCAACCGGACGGCAAAGAGGGTCGGGGCGGTGGCGACGGCGAGGCTGGCGAAGGCGAGGACGGCGAGGGCGATCAGGATCTGACGGTTTACGACTTCGAGGACAACGAGGACAACGCCACCGAGTACGAGGCCGAGGACGACAAGTCCAAGATCATCAAATTCTTGCCGAAAAAGTCACAGACCGTGACCCAAGCGCACATGTGCAATTATTGCAATTACACGAGTCCGAAGAGATACTTGCTCTCGCGTCACATGAAATCGCACTCCGAGGAGAGACCGCACAAGTGTAGCGTATGCGAGAGAGGCTTCAAGACATTGGCCTCGTTGCAGAATCACGTAAACACACACACGGGGACCAAACCGCATCATTGTAAATTTTGCGAGAGCGCCTTCACAACCTCCGGGGAATTAGTGAGACACGTCCGTTACAGGCATACTCACGAAAAACCTCACAAATGCCACGAGTGCGATTACGCGTCGGTCGAGCTGTCGAAGCTCAAGCGGCACATCAGATGTCACACGGGTGAACGGCCCTACCAGtgTCCCCATTGTACATACGCCAGCCCGGACACTTTCAAGCTCAAGCGTCACTTGCGCATTCACACAGGCGAAAAGCCCTACGAGTGTGACATATGCAACGCTCGTTTCACCCAATCGAACAGTTTGAAAGCCCACAAACTCGTGCACAATGTAGGCGACAAGCCGGTTTTTCATTGCGAACTCTGTCCAGCAACGTGCGGCAGAAAAACCGATCTGAGAATTCACGTGCAGAAGCTACACACCTCTGACAAGCCTCTCAAGTGCAAACGGTGCGGCAAAACATTCCCAGACAGGTACAGTTACAAGCTCCACAGCAAGACGCACGAGGGTGAAAAGTGTTACAAGTGCGATCTGTGCCCGTACGCTTCTATATCAGCACGCCACTTGGAGAGTCACATGCTCATACACACGGATCAAAAGCCGTACCAGTGCGACCACTGCTATCAGTCGTTCAGGCAGAAACAGCTGCTCAAGCGACACTGCAATCTCTATCACAATCCGACGTACGTGCCGCCACCGCCACAGGAGAAGACCCACCAGTGTCCCGAATGCGAGAGGGCCTTCAGGCACAAGGGCAATCTCATACGGCACATGGCCGTACACGATCCCCAATCGTCGCTGCAGGAGAAACAGCAAGCTCTCAAGATGGGCCGGCAGAAGAAGATACAGATCATCGACGGTCAGAGAGTCGAGGTTATGACTGGTGATTTAGCTTCTAAACTTAAAGgttacgacgacgacgaggaggaggacgaggacgaCATGATGGCGGTCGAGGGAAGCGACGGCCAGCAATACGTTGTTCTCGAAGTCATACAACTCGCCGACAATCAAGGAAGCGACCAGATGGCGGTGGTGGCGAACGAGGACGGTGACCTGATGATGCAAGATCCGCTGGGCCAAGAGAGCGGCCTTGTCGTGACGGCAGTGGAGAACggcgaggaggaggaggaggaagaggaggaggaggaggagatggTGATGGAGGAAATGAAGACGGAAACGGACGCGAGAGAGCCGTTGAAGCAGCCGCGTCAAACAACGCGAGCCGATCCCGCTCTCCGCAAAGAAATGGAAACTTGCTTCGGTTTCGACGACgacgaggaggaggacaaCGAGGAGGCCGGCGGAATGCGCTTACTCCAGACAATTTCgtaa
Protein Sequence
MSTNVATIKLEEGQESVTEIQTYLETFNKEIEGGQGEQLQHVQLQQVEGLSGGEEGGTYFVDQSGQYYYQASGDDAPVMTQVQIQEIDDGDGHEGEVSEEQYHEIEELDTVDGDEDGHNTENNRVVLNSGDAYQTVTIVPSDTNPGEVSYVLIVQQPDGKEGRGGGDGEAGEGEDGEGDQDLTVYDFEDNEDNATEYEAEDDKSKIIKFLPKKSQTVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHHCKFCESAFTTSGELVRHVRYRHTHEKPHKCHECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICNARFTQSNSLKAHKLVHNVGDKPVFHCELCPATCGRKTDLRIHVQKLHTSDKPLKCKRCGKTFPDRYSYKLHSKTHEGEKCYKCDLCPYASISARHLESHMLIHTDQKPYQCDHCYQSFRQKQLLKRHCNLYHNPTYVPPPPQEKTHQCPECERAFRHKGNLIRHMAVHDPQSSLQEKQQALKMGRQKKIQIIDGQRVEVMTGDLASKLKGYDDDEEEDEDDMMAVEGSDGQQYVVLEVIQLADNQGSDQMAVVANEDGDLMMQDPLGQESGLVVTAVENGEEEEEEEEEEEEMVMEEMKTETDAREPLKQPRQTTRADPALRKEMETCFGFDDDEEEDNEEAGGMRLLQTIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01001593;
90% Identity
iTF_01306705;
80% Identity
-