Oell002584.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ophion ellenae
Gene Symbol
topi
Assembly
GCA_963210295.1
Location
OY723385.1:55453797-55458008[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.088 11 7.5 1.1 1 23 263 285 263 285 0.95
2 16 0.46 60 5.2 0.6 2 23 292 314 291 314 0.83
3 16 0.0038 0.5 11.8 0.3 2 21 321 340 320 341 0.92
4 16 1.6e-05 0.0021 19.3 1.3 1 23 348 370 348 370 0.97
5 16 1.2e-05 0.0016 19.6 1.5 1 23 376 398 376 398 0.95
6 16 0.085 11 7.5 3.8 2 23 410 432 409 432 0.93
7 16 0.028 3.6 9.0 0.8 1 23 448 470 448 470 0.96
8 16 0.38 49 5.5 0.0 3 23 478 498 476 498 0.94
9 16 0.049 6.4 8.3 2.4 1 23 508 531 508 532 0.95
10 16 0.0014 0.18 13.1 0.0 1 21 547 567 547 568 0.94
11 16 0.0091 1.2 10.6 0.3 1 23 573 595 573 595 0.98
12 16 2.4e-06 0.00032 21.8 3.1 1 23 601 623 601 623 0.98
13 16 0.00043 0.056 14.8 0.4 1 23 629 652 629 652 0.97
14 16 0.059 7.7 8.0 0.7 1 23 658 680 658 680 0.89
15 16 3.9e-07 5.1e-05 24.3 2.2 1 23 686 708 686 708 0.99
16 16 7.5e-06 0.00097 20.3 4.9 1 23 714 737 714 737 0.96

Sequence Information

Coding Sequence
ATGACGAGTACGACAagagtcgtcgattcgaacagcGCGACACCGAGCGACACGGACGATTGTTATGACGATGACGTCGGCGAAGCGAGCCTCGTATGGTCACAGGACGATCCTCACTCGACCAGCGATTTTATAAACTCTGAAACCGGAAAGAGATCGACGAATACCGACGAGGAAAATTCCGGAGGACTTTGCCGATTGTGCGCTGGACGTGCGATCGATCCAGTCTACATTTACTCCGAGTTTGGTGAATCTATGAGACTCGCGCACAAAATGAACACGTGCTTGAGCGTAAAGATAAAAAAGACAGATCCTCTTCCGAAGCAGTTGTGCCACCCCTGTGTCGAGAAGATCAACTGGTGCGACGCTTTCGACAAGCACTGCATCAGAGCCGAGGAGACGCTCGCAACGATGCTGCGAGACGAAAGAGAACGAGCGGCGACCACGGAAATGTGCAGCGCCGAGGCAGAGACGCGCGACGAGCAGTCTTGTCCTCTGTGTGTGAAAGGGCACATGCGCACGAGTGCGCCGAGCGTTACGACGACGGGCGTCCCTACCGAGGATCTGTACGACAGCGACGTCGTGATGGACAGCAGCGACGAAGAGAAGGCATCTGCCAATCTGTCCAGACCGAGGCCCGAGTCGAGCGACGATCCGGCGCGACTCGGCGCTCGTGCCAATGGCCAGCAATATCTTAAATGCGGCGCTTGCATGAATCTCTATCACACCAGAGAAAATTTGGACGTTCACAAGTGCAAGCCGAGCGTACAGGTGACCTCGAGACCGTACAAGTGTTCAATTTGCGACACGATCTATCCGTTCGAGGAACGTCTGAAATTTCACATGCAATTTCACCAGGGCGCCAAGGAGCTCTATTGCCCCATATGCAATATAACGTTTGGCAAAGAGTTGAAGGCCTTTTATCACTACAAGCGTTATCATTGCGAGAACAAGAGCGTGTCTTGTTTGCAGTGTGGCAAATTGTTCGCCAGCCAGCAAGAATTGAGATCGCACGTATGCGTCGACGGTAAAACGCGACCTCACGTTTGCGAGATATGCAGCAAATCATTCACCGACGGTTACACCCTCAAGCGTCACGTGGTTACGCATCTCCCGGAAAAGCCGTACAAGTGTGTCCAATGCTCCAAGAGTTTCACGCAAAAATCACGGCTCAACAAGCACGTCGCCGGCCACGGGGTGGTCGTGGAGAATACTCAGGTAGCCTGGAAATGCTCCGAGTGCGGTCAGACCTTTGCCAGCTGCAACGACGCGGACACTCACAATCGTAAGTGCCACGGCGACAAGACAAGTCTCATCGAGGAATTGACCACTTCGAAGATCTATCATTGCGAGTTTTGCAACAGTTTTTTCAACGATCCCGATAGCCTCGGCGAACACGAGGCTCGTCACGTAGCGGAGAAGCCTTACGGGTGCGAGATCTGCGAAACCGTGTACAAATCGTACGCCGAGGCGGTACTACACTGGAAAGAGCATACGCAAAGTTTTCGAGTCGAAACGGCCTATCTGTGCGACGTATGCGGCAAGGACATGAAGGAGATGTCGCTTCTCTACAAACACAGGCGCAAGCGACATCACGTTACGGCCCGAAAATCGGAGCTCGACGATACCGCGAGAAAGTACGTTTGCGAATTGTGCGGCAAGTTGTTCGACGAGCGCGACGATCTGCGTATACACGGCAGGGATCAATGCTCGAAATTCCCGTGCGACATATGCGGCAATTTGTTGCCAACCGCTAATTCGTTGCACGCTCACAAGCGACGTCACAACGGCCTGCGACCCTACGTGTGCAACATATGCGGCAAGAGTTACACCCAATCGAGCCACATGTGGACCCACAAGCGATTTCACATGGGTGTAAAGCCTTACGCCTGCCAATACTGCGATCAGAGATTCACGATTAAGCCCGATCTCGCCGATCACGAGAGGAAGAAACACACGCGCGAACGACCGTTCAAGTGCGACGTTTGCAACAAGGCATTTCTCACCGGCTCGGTTTTCTATCAGCATCGATTGATCCATCGGGGCGATCGACGATACAAGTGTCACTATTGCGAGAAAGCATTCACCAGGACCGAGGCTCTCAATAATCACATTAAAATACACACCGGTGAGAAACCTCACGCATGCGACGTTTGCGGCAGATGTTTCAGGCAAAAAGGCGATATGAGGAAGCACAGAAGGACTCAACACAATCTCCCTAAAGAAGAGTTGCCGTGA
Protein Sequence
MTSTTRVVDSNSATPSDTDDCYDDDVGEASLVWSQDDPHSTSDFINSETGKRSTNTDEENSGGLCRLCAGRAIDPVYIYSEFGESMRLAHKMNTCLSVKIKKTDPLPKQLCHPCVEKINWCDAFDKHCIRAEETLATMLRDERERAATTEMCSAEAETRDEQSCPLCVKGHMRTSAPSVTTTGVPTEDLYDSDVVMDSSDEEKASANLSRPRPESSDDPARLGARANGQQYLKCGACMNLYHTRENLDVHKCKPSVQVTSRPYKCSICDTIYPFEERLKFHMQFHQGAKELYCPICNITFGKELKAFYHYKRYHCENKSVSCLQCGKLFASQQELRSHVCVDGKTRPHVCEICSKSFTDGYTLKRHVVTHLPEKPYKCVQCSKSFTQKSRLNKHVAGHGVVVENTQVAWKCSECGQTFASCNDADTHNRKCHGDKTSLIEELTTSKIYHCEFCNSFFNDPDSLGEHEARHVAEKPYGCEICETVYKSYAEAVLHWKEHTQSFRVETAYLCDVCGKDMKEMSLLYKHRRKRHHVTARKSELDDTARKYVCELCGKLFDERDDLRIHGRDQCSKFPCDICGNLLPTANSLHAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACQYCDQRFTIKPDLADHERKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHNLPKEELP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01102253;
90% Identity
iTF_01103750;
80% Identity
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