Basic Information

Insect: Ophion costatus
Gene Symbol: zfh1
Assembly: GCA_951751655.1
Location: OX632356.1:10448188-10461342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.013 1.5 9.9 1.3 2 23 82 104 82 104 0.92

2 7 9.2e-06 0.0011 19.9 0.6 2 23 124 145 123 145 0.97

3 7 5.7e-06 0.00066 20.5 7.8 1 23 154 176 154 176 0.99

4 7 1.4e-05 0.0016 19.3 1.9 1 21 182 202 182 203 0.95

5 7 8.9e-05 0.01 16.8 4.2 1 23 658 680 658 680 0.94

6 7 0.00026 0.03 15.3 9.7 1 23 686 708 686 708 0.98

7 7 0.0015 0.17 12.9 4.3 1 21 714 734 714 735 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.013	1.5	9.9	1.3	2	23	82	104	82	104	0.92
2	7	9.2e-06	0.0011	19.9	0.6	2	23	124	145	123	145	0.97
3	7	5.7e-06	0.00066	20.5	7.8	1	23	154	176	154	176	0.99
4	7	1.4e-05	0.0016	19.3	1.9	1	21	182	202	182	203	0.95
5	7	8.9e-05	0.01	16.8	4.2	1	23	658	680	658	680	0.94
6	7	0.00026	0.03	15.3	9.7	1	23	686	708	686	708	0.98
7	7	0.0015	0.17	12.9	4.3	1	21	714	734	714	735	0.96

Sequence Information

Coding Sequence: ATGCACACACGGCACGACAGGACGAATCTATCGAGGATAGGGTGCAGCGAGGACGAAGCCGGCGCCGAGCTCGCCGAAGTCGCGGATTGCGCGGCGGGGGCTGCAACCGACGGAGCCGGTCGTGGTGGGGGCGGCAGCAGCGGCGGTGGAGGAGGAACAGGAGGTGAAGCCGCTGGAGGAGGCGCCGGTGTGGCCAGTAGCGGCGGTGGAGGCGAGGCCGGCTCGACGAAGCAGCAGGGCGAGAGATGCCCACAGTGTGGCATGATTTGTAGAAATTCACACGTTCTTCAGCTTCATCTCGAGGACATCCACAAAACGTCCTTCGCCAGCATCGACAAGCACGATTTGAACGCTCAATTTTCCCAAGTTTCCTGCAAAGTGTGCAACAAGACATTTGCGAACGTCTATCGGCTGCAAAGGCACATGATCAGCCACGACGAGAGCGCAGTTTTGCGTAAATTCAAGTGCCCGCACTGTGAAAAAGCCTTCAAGTTCAAACATCATCTCAAGgaaCATCTTCGAATTCACAGCGGAGAAAAGCCATTCCAATGCAACAATTGCGGCAAACGTTTCTCCCATTCGGGCTCGTACTCGAGTCACATGACGTCGAAGAAGTGTCTGATTGTGAATCTGAAGAAATCCCGACAGAGCTCGATAACGTCGAGTGTCGAGCGCGTCGCAAAGAAGTCCCAGCAGAATCTGTCCAATCCACGCCGCGACATTGTCGATCTTCACGTTTCAAACAACAACACGTTCATGCCGATATTGCCGAAGTTGTCGCCCTTGGACTATCAAGACATACAGCGAGACGGAGCAGGTATCTACGACATGCCGACCCTTCTACCCCAGATGATGGGCTTTGGCAGTTATTTTCTGCAGTCGTCGATAGGAAAGATTCTCAATCAATTGCACACGAAACGATTGGACGAGGTTGCCGAACAATTTGAATCGCGCCGCGAGGTGATGAGCCCGTCGACCGCCGATTCCGAGGGCACCGAAGGCACGGAGGGAAAGAATTCACCGTCGCCAACGGATCCCCAGGGTATGGACGCGGTCAGGCGAATTCTCGAGACGGTCAACACTTCGGTGACGAAACAATTGCTCGAGGCAAACGTCAGAAAGTTAGCCTCGTCTCCTGCCACTATCAAGCGGGAGTACGACGAAGATTATCAGGACAGCGAGATGTCGAGCGAAATGACGCAAAGTCAGGACTGGCAAGTGGCAGATCAGTGTGACTCACAGAGCGAGGGCCTCGCTGCGAAACTCGAGGACGTCAATCCACCGTCGTCGGAACGTCATATCTACAAGAGAAAAGCCGAAGACAATGGCGTCGACACTTCCGAGGGTGATACGGACGACGAGGAGAGTACACAGCCGCAAAATGAATCCGGCAGGCGGGTCCGAGCGCGCTCGTTGATCGACGACGAACAGTTGGCCGTTCTTAAAGGTTACTACGCGATCAATCCACGCCCCAAGAAGGAAGAAATTGCCATGATAGCGAATTATATTAATTTCCCTACGCGGGTCGTTCAGGTTTGGTTCCAAAATTCTCGGGCGAGAGATCGCAGGGAATCAAAGATACCGGCTCTCGTACCGCTCGCGAGTCTCGGCAATCATACGAATCTCGAACAACCGCTTGACCTGTCAAAAAAAGAAGCTTACACGATATCCGTCGTGAAGGACAGTGACGGAGGCTCGAGCAGACACACCGCGTCACCGTGTGGCCCTAAGGAGGAACAAACTCGTCCAATTTCTCAAACTCACAATGATAGCGAAGACATCGATGATTCGCCGCTCGTCATCGACGAGGAGACTACCGATTGCGGCGAAGTCAAGAAACCCGAGGTCGTCAGTACCGAGGAAATCATAGTCAAGAACGCACCCGTCAGCCAAGCAAAGACGGTTGAACCACCCGTGGTCAATACAACAACGGAAGCACCGCCACCCGCCGAAAACGAGCAAGAAGGCTTATACTTTTGCGATCAGTGCGACAAAACGTTCTCCAAGCACAGCTCCCTCGCGAGACACAAGTACGAACATTCCGGACAAAGGCCTTATAAATGCGAGAAGTGCACACGTGCTTTTAAGCACAAGCATCACCTCACGGAACACAAGAGGCTCCATACCGGCGAAAAACCCTTCCAGTGTTCAAAGTGCCTGAAGCGATTCTCCCACTCGGGTTCCTACAGCCAGCACATGAACCATCGTTACTCGTACTGCAAGCCATACAGAGAATAG
Protein Sequence: MHTRHDRTNLSRIGCSEDEAGAELAEVADCAAGAATDGAGRGGGGSSGGGGGTGGEAAGGGAGVASSGGGGEAGSTKQQGERCPQCGMICRNSHVLQLHLEDIHKTSFASIDKHDLNAQFSQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRQSSITSSVERVAKKSQQNLSNPRRDIVDLHVSNNNTFMPILPKLSPLDYQDIQRDGAGIYDMPTLLPQMMGFGSYFLQSSIGKILNQLHTKRLDEVAEQFESRREVMSPSTADSEGTEGTEGKNSPSPTDPQGMDAVRRILETVNTSVTKQLLEANVRKLASSPATIKREYDEDYQDSEMSSEMTQSQDWQVADQCDSQSEGLAAKLEDVNPPSSERHIYKRKAEDNGVDTSEGDTDDEESTQPQNESGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIAMIANYINFPTRVVQVWFQNSRARDRRESKIPALVPLASLGNHTNLEQPLDLSKKEAYTISVVKDSDGGSSRHTASPCGPKEEQTRPISQTHNDSEDIDDSPLVIDEETTDCGEVKKPEVVSTEEIIVKNAPVSQAKTVEPPVVNTTTEAPPPAENEQEGLYFCDQCDKTFSKHSSLARHKYEHSGQRPYKCEKCTRAFKHKHHLTEHKRLHTGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00266735;
90% Identity: iTF_01103806;
80% Identity: iTF_01100479;