Basic Information

Gene Symbol
Zbtb41
Assembly
GCA_001266575.1
Location
JTDY01005133.1:13956-15431[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0002 0.013 15.9 3.7 2 23 176 198 175 198 0.96
2 10 0.2 13 6.4 0.8 2 21 204 223 203 224 0.93
3 10 3.1 2e+02 2.7 1.3 1 23 246 268 246 268 0.93
4 10 0.00015 0.0093 16.3 2.0 1 23 274 297 274 297 0.92
5 10 0.037 2.4 8.7 4.6 2 23 305 326 305 326 0.96
6 10 1.3e-05 0.00084 19.6 1.6 1 23 331 353 331 353 0.98
7 10 4.4e-06 0.00028 21.1 2.0 1 23 359 382 359 382 0.95
8 10 1.6e-05 0.001 19.3 0.8 1 20 388 407 388 410 0.93
9 10 0.011 0.69 10.4 1.0 3 23 417 437 417 437 0.99
10 10 3.3e-05 0.0021 18.4 1.8 1 23 442 465 442 465 0.98

Sequence Information

Coding Sequence
ATGGAGGAGGAACATAAAAATGATATCTGCCGCGTATGCTTAAATTGTGACTTCGATAGTAAACCTGGCGAAAATTTATCTTTGTTCGAAAAATACAACGATTGTATGATCTCGGACAAAATGAATGCCCTCACCAACATCGGCATCACTGAAGGAGATGGTTTGCCTGACAAGATATGCCCAACTTGCCTCCTTGAACTAGAAAGCGCCTTCGAGTTCAAggtaaaatgtgaaaaaaacaacgaaatttTACTGTCTGCGGTAAACAATGTTTCAACTCAATTAAAAAGCGAAGACGACGATCTTTCTATAAAGGATGAATGCATAATTGATGATAATTTCAATGTTCCAACACCATTGGAAAGCGACGACACCTCTCTCTCTATGAAAGAAGAATACCTAGATGATGACAACAATACAGATGGGGACGAAAATATCCCACTGGCTGACTTACAAGCTGCTGACGCTGACATAAAGCCGTTCATCGAGCCGCCCAGACCCAGTAAAGCAATAGACTTGAAACTAGAATGCCACGACTGTGGCGGATCCTTCAAGAGTAAGTGCAAGCTTCGTGTGCACTGGAAGAAGGTACACATGACTGAGCAACTGAAATGTCCAAATTGCTTAAGTAAGTTCAAATCCTATGCAGCCTACAACTCACACAAGAAACGTAAATTGACCAGTTGTGTCACGGCCAGCAAGGTCCGCATCGAAGGTGAAGGCAAGCACCGTGTATTCCACTGCAAAGATTGTATTTATCACAGTGAGCGTATTAGTGATATGTCAGCACACATAGTCATACACTCAGGAGAGCGCCCGTTCCAATGTGACATTTGTCTCAGATCCTTTACTCAACACAGCTCATTGTCATCACATAAGGAAGCCTCTCACAAAGTGTACATAGCTGAAGGAACCTGTCACTACTGTGGAAAGCATATTCAGGGTCGGACAAAACTATACAGACACATGGAACAACATAGACGTAACAATTTTCCATGCAAGATTTGCAGCATTGTGCTAAAATCCAAAAGCAGTTTCAAGAATCATATGAAAAGGCATTCCGGCATCAAGGCCTATGCATGCGAAATTTGCCCAAAGTCATTCTACACACAAAGCGAACTCTGCAACCACAAAACTAAAGTTCATCTcaaaacaaaaacttacaaatgTGAAATATGCGATTACACTACTTCTACGAGCAGTGCATTGAAAACACATCAACCAAAGCACTCGGCTTCAAATGCTGGTTGTAATGTTTGTGGCATGTTTTTTGACAATGATCTACAACTGACCCTCCATAAAAAGAGGCACACTGACAGGCGTTATCAGTGccctcactgtgaaaagaaatATTACTCAGGGAAAAATCTTTCTGCACATGTAAGGATAAAACACAGGATTGTTAAGTTGAGTGGACGTGGACCAGCTTTTAAAGTAAACTGTGTGAAGAGTGAATGTCcaaaagcaaaaaaataa
Protein Sequence
MEEEHKNDICRVCLNCDFDSKPGENLSLFEKYNDCMISDKMNALTNIGITEGDGLPDKICPTCLLELESAFEFKVKCEKNNEILLSAVNNVSTQLKSEDDDLSIKDECIIDDNFNVPTPLESDDTSLSMKEEYLDDDNNTDGDENIPLADLQAADADIKPFIEPPRPSKAIDLKLECHDCGGSFKSKCKLRVHWKKVHMTEQLKCPNCLSKFKSYAAYNSHKKRKLTSCVTASKVRIEGEGKHRVFHCKDCIYHSERISDMSAHIVIHSGERPFQCDICLRSFTQHSSLSSHKEASHKVYIAEGTCHYCGKHIQGRTKLYRHMEQHRRNNFPCKICSIVLKSKSSFKNHMKRHSGIKAYACEICPKSFYTQSELCNHKTKVHLKTKTYKCEICDYTTSTSSALKTHQPKHSASNAGCNVCGMFFDNDLQLTLHKKRHTDRRYQCPHCEKKYYSGKNLSAHVRIKHRIVKLSGRGPAFKVNCVKSECPKAKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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