Basic Information

Gene Symbol
-
Assembly
GCA_001266575.1
Location
JTDY01001204.1:90177-94254[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.049 3.1 8.4 0.8 1 23 230 252 230 252 0.93
2 18 0.00011 0.0067 16.8 0.6 1 23 256 279 256 279 0.94
3 18 0.0019 0.12 12.8 0.5 1 21 283 303 283 304 0.95
4 18 0.0015 0.098 13.1 1.3 2 23 312 334 312 334 0.94
5 18 0.03 1.9 9.0 1.1 1 23 341 364 341 364 0.94
6 18 7.5e-06 0.00048 20.4 1.9 1 23 368 390 368 390 0.98
7 18 0.0033 0.21 12.1 2.3 1 20 396 415 396 417 0.94
8 18 8.2 5.2e+02 1.4 0.0 2 15 511 524 510 527 0.84
9 18 0.39 24 5.5 0.3 2 23 549 571 548 571 0.91
10 18 0.4 25 5.5 0.1 2 23 596 618 595 618 0.96
11 18 0.24 15 6.2 0.7 2 23 639 660 638 660 0.93
12 18 8.7e-06 0.00055 20.2 0.4 1 23 664 687 664 687 0.97
13 18 0.47 30 5.3 3.6 1 21 692 712 692 713 0.93
14 18 0.14 8.7 6.9 1.0 1 23 720 743 720 743 0.94
15 18 0.0079 0.5 10.8 1.8 1 23 750 773 750 773 0.93
16 18 0.003 0.19 12.2 0.6 1 23 778 800 778 800 0.96
17 18 4.6e-06 0.00029 21.0 0.5 1 20 806 825 806 828 0.94
18 18 0.00044 0.028 14.8 2.9 1 23 834 857 834 857 0.97

Sequence Information

Coding Sequence
ATGCCCGTTGACATGAAACGTTTCCGTGGCATGAAAGTGAACACGCGTAGCACCTCTCTCGATGACGAATGGATCACGACAGATTTGCCGGGAACAATTCAGATTGATATCAAACGAGAATTGCCAAGTGCCACTGAAGAAAACCCACAGTCTTGTATCAAACAAAACTATGTAGTAGATGACGAATGGATCATTACAGATATGACTAAACAAATGGGAAAAAGAAAACTGAAATCTTCCGATCTGATCGGGCTTAAAATTCAGTCGTGCTTGAAACAAGGCATCGGTCTAAAGTCTAAAAAACGTGGCAAACGGGTTAAACAACCCAAAAAGTTCTTACACAATGCTCGGCTGATACTGAGGTACACGACGGCGATCCCTTACAGAATCGAGCTCGCTAGCTCGCTTGTGCCGTGCTTTGCGTGTCAGGATAAATTCAAGGACCCGTTTTTGTTCAGAGATCACTTCCTTGCGGAACATAAAAGTGCGGACAAGACTAGAGGCATGCACTTGTTTAATAATGTTCAGACTCGCGCCGATATAACTGACCTAGCCTGCCTTTTATGTGCGCAATTATTCGATACTTTAGAGGAAGCAGCAGGACACCTCGTCCAGGAACATCAAATAAATATAGACTTTAAAGAGAGATTGGGTCTTGTGCCACTGAAATTCCCCCAAAAGGGTATGTATATATGCGCGATATGTCAAAGGAAATCCTCTACTTTTAGAGATCTGTACAGACACTCCGGCTCGCACTTCTACTTTCATGTCTGTGAGATTTGTGGTAGGCAGTTTGAGTCCATGTCAGCATTGAAAAGTCATCTGAGTCAAAGCCATGTCGAAGGTCATAAGTGCACATACTGCAAGACCGTGCTCCCCACCGCAAAAGAGCTAAAACAACACGTCAAAGTCAATGCTAGGTGCGCATCCGGTTATTGCAAGATTTGTAAAAAATCTTTCGGATCTATGGATCGTCTTCAAAAACACAAGGAATCTGTACACGGAGCTCCGAAAAGAATATATGAATGCGCCGAGTGCTCAAAAGTATTCGAAACACGTATGAGTCAGTATCTGCATTTTAAAAAAGAACACACCGATCATTATAAGTGTGGAAATTGTAgcaaaaaatttacaaattctAAATCTTTGAAATTGCATTTGTTAGTTCACACTGGTGAACGACCATTTAAGTGTGAATTTTGCCAACAAGCGTTCAAAAGTTCATGCTACTTAAAGATTCATGTTGCAAAATGTCAATTGTCACTAAAGTACATCACTAGAGAACATAAAAGTGCGGACAAGACGAGGGGCATGCACTTGTTTAATAATGCTCAGACTCGCGCCGATATAACTGACCTAGCCTGCCTTTTATGTGCGCAATTATTCGATACTTTAGAGGAAGCAGCAGGACACTTCGTCCGGGAACATCAAATAAATATAGACTTTAAAGAGAGATTGGGTCTTGTGCCACTCAAACCCAAGAGGAGGTCTGTGCAGGCACTCTGGTTCCCACTTCTACTATTCTGTCTGATCTGTGAGATTTGTGaaTTGAAATACCCGAATGCGTCTGCGGCGAAGCGCAACGCCGAGGTAATCGTCAGACATTCGACAGTGTACCCGTTCAGACTACCAGAAAACTGTATGGTCTGTGTGTTCTGCTGCGAAAGTTACGAGGAGCCCTCGGCATTTAGAAGGCACATGGATATCGAACACCAGACGTTTTCAATCCGAATGGCGTTCGCACATTGCTCTGAGGGATTCCTTAAAGCGGACTGCTCGGACATCCGATGCCGCATCTGTTTCAAACCGAGTGACAGTCTCGAAGGAATCGCTATTCATTTACGAACATCTCACCAAAAACCATTGGATTTGACAGTTCCTCTAGGAATACAGCCTTTCAAACCGGATAAACTTAAATGCGCACTTTGCGATACAAAAGCATTTGGCCTCCGACAGCTCAGCCGGCACACACAGACTCATTTCCTGAGGTTCACCTGTGAATCTTGCGGAAAGTCTTACGCCACCAATACCGCTTTACAAGTCCATATCAAATACTCGCACATTATTAAAGAACATTACTGtagaaaatgtaaaactaaaTTCAGTTCGACAGAGGCAAAGAGAAATCATTTGCAGAAATCTACAAGATGCTGGTCGTATTTGTGCAATATGTGCGGCGATAGGTTTATATCCTGGAACACGAAGCATCTTCACATGAAGGAGGCTCACGGGGTTGCAGAGGAGCCCCACGTCTGTCCAGAATGTGGCAAGATTTTTGCAGAGAAGAAGGCCTGCCGACAACACTTTAAAGTCGCGCACACGGATGACAACTTTGTTTGCTCCTTCTGTGGTCTGAAGTTTCCTACAAAAATGAAATATGAAGAGCACAGAGTTATTCACACAAACGAAAAACCCTACCCGTGTACTGTTTGTTCCAAGATGTTTTCTAGGAAGAAGAATTTAGCCCAGCACATGTGGATACATAGCGAGTATAAAAGATTCGAATGCAAGCTCTGTAACAAGAAGTTTAATCAGAGAGTCAGCTGGAAATcgcacaacaaaacaaatcatCCAGAACTATTGAAATTTGAGCAAGAACAGGATAATAGTGTCAAATATCTAATGTCCGTATTAAAGAAG
Protein Sequence
MPVDMKRFRGMKVNTRSTSLDDEWITTDLPGTIQIDIKRELPSATEENPQSCIKQNYVVDDEWIITDMTKQMGKRKLKSSDLIGLKIQSCLKQGIGLKSKKRGKRVKQPKKFLHNARLILRYTTAIPYRIELASSLVPCFACQDKFKDPFLFRDHFLAEHKSADKTRGMHLFNNVQTRADITDLACLLCAQLFDTLEEAAGHLVQEHQINIDFKERLGLVPLKFPQKGMYICAICQRKSSTFRDLYRHSGSHFYFHVCEICGRQFESMSALKSHLSQSHVEGHKCTYCKTVLPTAKELKQHVKVNARCASGYCKICKKSFGSMDRLQKHKESVHGAPKRIYECAECSKVFETRMSQYLHFKKEHTDHYKCGNCSKKFTNSKSLKLHLLVHTGERPFKCEFCQQAFKSSCYLKIHVAKCQLSLKYITREHKSADKTRGMHLFNNAQTRADITDLACLLCAQLFDTLEEAAGHFVREHQINIDFKERLGLVPLKPKRRSVQALWFPLLLFCLICEICELKYPNASAAKRNAEVIVRHSTVYPFRLPENCMVCVFCCESYEEPSAFRRHMDIEHQTFSIRMAFAHCSEGFLKADCSDIRCRICFKPSDSLEGIAIHLRTSHQKPLDLTVPLGIQPFKPDKLKCALCDTKAFGLRQLSRHTQTHFLRFTCESCGKSYATNTALQVHIKYSHIIKEHYCRKCKTKFSSTEAKRNHLQKSTRCWSYLCNMCGDRFISWNTKHLHMKEAHGVAEEPHVCPECGKIFAEKKACRQHFKVAHTDDNFVCSFCGLKFPTKMKYEEHRVIHTNEKPYPCTVCSKMFSRKKNLAQHMWIHSEYKRFECKLCNKKFNQRVSWKSHNKTNHPELLKFEQEQDNSVKYLMSVLKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-