Otau002973.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Onthophagus taurus
Gene Symbol
zfh1
Assembly
GCA_000648695.2
Location
NW:223645-306725[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00041 0.031 14.4 0.4 2 22 128 148 127 148 0.94
2 9 0.00017 0.013 15.5 0.7 1 23 178 200 178 200 0.95
3 9 9.1e-06 0.00069 19.6 0.6 2 23 207 228 206 228 0.97
4 9 9.5e-07 7.2e-05 22.7 5.9 1 23 237 259 237 259 0.99
5 9 4e-05 0.003 17.5 1.0 1 21 265 285 265 286 0.95
6 9 0.0031 0.23 11.6 2.2 1 19 491 509 491 509 0.91
7 9 1.8e-05 0.0014 18.6 1.2 3 23 830 850 828 850 0.94
8 9 9.6e-05 0.0073 16.4 9.4 1 23 856 878 856 878 0.98
9 9 0.0015 0.11 12.6 4.3 1 21 884 904 884 905 0.96

Sequence Information

Coding Sequence
ATGAGGGGCCCGGACATTTGCATATTGGCCAAACCCGGACACATCAGACGTTCCAGGAACCGAAACCTGTTCAAACAAGAACTATTTTGCGGCCACCGTCGAATCCTAACAGTGCGCTCCGAAAGAAAAATAACAGGATGGAGAGAAGTTGACGCAATGAGTCCGGACAGCAATCACAACGAGATTTCCGAAAATTCCGAGTGCCTAAGAAAGATTCTTCTTAATGGAGAAACGGAAGATAAAGAGATCGTCGAGTACATGCAAAGAAGAGACACTGCGGTGATTTTTCCCGAGGACACTCAAATCGtaCCAATATCAACTTCAAACGGAATCCGCGATCCCGAAGAGTTACCATCCCCATCTAACTCGGATTACTTCATGAAATGTCCTCAGTGCCAAAAGGGATTTCATACGTTCGAAGCCCTCAAAGTTCACATGGAGACGTGTCCGAAAGAAAACGGGCAAATCTCGAGTTCGCCGAATCTTTCCTCGGTGGTTATTCCATCGGGAGGTGGTAGTGCAGGGGGTTCACATCCATGTTCTCAGTGTTCTGCGAGTTTCATCAACAAGGATCAATTGGAGAAGCACGAACTGTTGCACTCTCCAAACGGTCAAGTGtCCTGCAAAGTTTGTAACAAAACTTTTGCGAATGTGTACCGGCTTCAAAGGCACATGATCAGTCACGATGAAAGCGccgttttaagaaaatttaaatgcaCCGAGTGTGATAaagcttttaaatttaaacatcacTTAaaggaACATATAAGAATACATAGTGGTGAGAAGCCTTTTGAATGTGGAAATtgtgggaaacgtttttcacATTCAGGTTCATACTCGAGTCACATgacatcaaaaaaatgtttggtgATGAATCTAAAATTGGGAAGAACTCGAGCTGCCAATAACGGCAATCACAACCTGCTGGTAGCCGATAAAACCCATCAAAatagaaatcaaaaaagaaacaactccgggattttaaacaacaatttagccGGCAGCCCGAATCAAAACGGGATGTTCTCAATCCTTCCTAAATACCCCGACACTTCGGCACTATTCCATCCCTTTTATATGCCCCCGCCCAACATGGGAAGCATCTCTTTACCTCCGTACTCAATTCCAACAATCGGGGAGTTCTTAGAGAAGCTCCAAAAAGTTTCGCCCCAAACCAACTTAATCGAGAACGATTGCAAAAGCGAGCACAACGAAGAAGATGGGGAATTAAACAAATCGAAATCGACGAGTTGTGGTGATTTAGCCATCGATGAAGAAGAAATCGAAGTGAAAGAAGAACCACAAGAAAACACCCCAGAAACGAATGGAAGAGATTTCGAAACTGTCAAAAGAATTTTAGAAACTGTAGGAGCCACGGTGACCAAAGAATTCCTTCAAGCCaatatccaaaaattttcttccGATACTTCCGATTGCAACAGTTTGTCCCAATCACCTTTAAGAGAGTTCCTTTGTCATGGTTGCAAAAAAACGTTTTCGTCCCAATCGTTTTTGGACGAGCACGATTGCGAGATGGACGTGAAAAGCGAAGGACTAGCAGCAAAATTAGAAGAGGCGATCAATACAAAATCAGAAAGTGATCACCCGAGTGGTTCCGACGAAGAATACGAGCGTTCCAACGAAATCGACGGAGAAAGAGTCGCAACAACAGACCAACTCAGCGATGATGGCAGAAAAGTTCGCGTTCGCTCCTTAATTTCCGacgaacaattaaaaatattaaaagataattacGCGATGAATCCGCGACCCAAACGCGAGGATTTAATCCGAATCGCTGATCAAATCGGGTTCTCAGTTCGCGTGGTTCAAGTTTGGTTCCAAAATACTCGGGCTAGAGATCGAAGGGAAGGAAGATTGATTCAAATCCCTTATTCAACACCTCAGCAGAGTTATCCCCAAAAATATTCTAATTCAAACCTTCCCCGTAGTCCTTATTACCTCCCAAAAGACACCTACATCTCAGAACAACCCCTCGATTTATCCACGAAAAAAGATCACACCTCCAGAGAATCATCCCCGGCGTCTTCCCCAGCACCCAATTCGATCCAAAATTCCGATTCGGGCgaagaaatcgttaatttaAGCCAAAAATCTTCGAGATCGCCGACCCCTTTTCGAAATTATCCCTATCAAAGCTCGAATTGTTCTTCGGAACCGATTAGAAGTCCTTCGCCGGGAGATTATAACAACGGAAGTCGGTTGGCGCAGATTTTGGCGCAACCTAAGTTACCTATCCCTTCTGTTCCTATGTCTTTGGTTCCAATGGATAGATTGATTCAATTTGGAAATCAagatttgcaaaattttagcCAATTGATGACCACGAAGAGGACTTGGTCTGAAGATGGAGATGCGACGCAAGAAAGTGTGGAAGAGAGCGggaataaaaagttaaaagtgGTTAAAGGCGTTGATAGTCCAATGTTGAGTGGCCAAGAAGATGTTGAGGGATTGTTTGGATGCGACCAATGTGATAAATCATTTTCGAAGCAAAGTTCTTTAGCTAGGCATAAATATGAACATTCAGgTCAACGTCCACACAAATGCGACGAATGTCCAAAAGCATTCAAACACAAACATCACCTAACGGAACACAAAAGATTACACAGCGGTGAGAAGCCCTTCCAATGTTCGAAATGTTTGAAGAGATTCTCGCATTCCGGTTCTTATAGCCAACATATGAACCACAGagtaCCTCTTTAA
Protein Sequence
MRGPDICILAKPGHIRRSRNRNLFKQELFCGHRRILTVRSERKITGWREVDAMSPDSNHNEISENSECLRKILLNGETEDKEIVEYMQRRDTAVIFPEDTQIVPISTSNGIRDPEELPSPSNSDYFMKCPQCQKGFHTFEALKVHMETCPKENGQISSSPNLSSVVIPSGGGSAGGSHPCSQCSASFINKDQLEKHELLHSPNGQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAANNGNHNLLVADKTHQNRNQKRNNSGILNNNLAGSPNQNGMFSILPKYPDTSALFHPFYMPPPNMGSISLPPYSIPTIGEFLEKLQKVSPQTNLIENDCKSEHNEEDGELNKSKSTSCGDLAIDEEEIEVKEEPQENTPETNGRDFETVKRILETVGATVTKEFLQANIQKFSSDTSDCNSLSQSPLREFLCHGCKKTFSSQSFLDEHDCEMDVKSEGLAAKLEEAINTKSESDHPSGSDEEYERSNEIDGERVATTDQLSDDGRKVRVRSLISDEQLKILKDNYAMNPRPKREDLIRIADQIGFSVRVVQVWFQNTRARDRREGRLIQIPYSTPQQSYPQKYSNSNLPRSPYYLPKDTYISEQPLDLSTKKDHTSRESSPASSPAPNSIQNSDSGEEIVNLSQKSSRSPTPFRNYPYQSSNCSSEPIRSPSPGDYNNGSRLAQILAQPKLPIPSVPMSLVPMDRLIQFGNQDLQNFSQLMTTKRTWSEDGDATQESVEESGNKKLKVVKGVDSPMLSGQEDVEGLFGCDQCDKSFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRVPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01097853;
90% Identity
iTF_01097853;
80% Identity
iTF_01098393;