Basic Information

Insect: Onthophagus sagittarius
Gene Symbol: ZEB2
Assembly: GCA_036711965.1
Location: JASERS010000008.1:17170008-17172105[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0062 0.77 11.8 0.5 1 19 133 151 133 153 0.96

2 16 8.1e-06 0.001 20.8 0.7 2 23 158 179 157 179 0.97

3 16 0.12 15 7.7 0.1 2 23 219 240 218 240 0.91

4 16 0.027 3.3 9.8 1.5 3 23 245 266 243 267 0.92

5 16 0.11 14 7.9 0.3 1 23 275 297 275 297 0.94

6 16 9.6e-05 0.012 17.5 0.2 3 23 303 324 302 324 0.97

7 16 0.022 2.8 10.0 0.6 2 23 368 390 367 390 0.96

8 16 0.0028 0.35 12.9 4.2 3 23 396 417 395 417 0.94

9 16 0.00074 0.091 14.7 0.7 2 23 448 469 447 469 0.97

10 16 0.00069 0.085 14.8 2.0 1 23 475 498 475 498 0.97

11 16 1.9e-05 0.0023 19.7 2.4 1 23 511 533 511 533 0.99

12 16 1.3e-06 0.00015 23.4 0.5 1 23 539 562 539 562 0.98

13 16 7.1e-07 8.8e-05 24.2 1.0 1 23 568 591 568 591 0.95

14 16 0.0076 0.94 11.5 4.7 1 23 600 622 600 622 0.97

15 16 2.4e-05 0.0029 19.4 0.9 1 23 628 650 628 650 0.96

16 16 9.8e-06 0.0012 20.6 3.7 1 23 656 678 656 678 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0062	0.77	11.8	0.5	1	19	133	151	133	153	0.96
2	16	8.1e-06	0.001	20.8	0.7	2	23	158	179	157	179	0.97
3	16	0.12	15	7.7	0.1	2	23	219	240	218	240	0.91
4	16	0.027	3.3	9.8	1.5	3	23	245	266	243	267	0.92
5	16	0.11	14	7.9	0.3	1	23	275	297	275	297	0.94
6	16	9.6e-05	0.012	17.5	0.2	3	23	303	324	302	324	0.97
7	16	0.022	2.8	10.0	0.6	2	23	368	390	367	390	0.96
8	16	0.0028	0.35	12.9	4.2	3	23	396	417	395	417	0.94
9	16	0.00074	0.091	14.7	0.7	2	23	448	469	447	469	0.97
10	16	0.00069	0.085	14.8	2.0	1	23	475	498	475	498	0.97
11	16	1.9e-05	0.0023	19.7	2.4	1	23	511	533	511	533	0.99
12	16	1.3e-06	0.00015	23.4	0.5	1	23	539	562	539	562	0.98
13	16	7.1e-07	8.8e-05	24.2	1.0	1	23	568	591	568	591	0.95
14	16	0.0076	0.94	11.5	4.7	1	23	600	622	600	622	0.97
15	16	2.4e-05	0.0029	19.4	0.9	1	23	628	650	628	650	0.96
16	16	9.8e-06	0.0012	20.6	3.7	1	23	656	678	656	678	0.98

Sequence Information

Coding Sequence: ATGACTTCCGCGTGCAGGCTGTGTTTAAACTCGTCCTCGAGCGATTATCGAGACTACAAAAGCGTCGATCAAAAATACTTCGACGTCGTCCTTCCAGAAATCGATATAACAATGATAAGTTCCCCTATTCTCTGCATAAATTGCGTCGAATTACTTCGAGCCGCTTATTTATTTAAGTCGAATTGCCTGGAGACTGAACGCCTTATAAAAGCTTACATAGAAGGAGTGGGTGGTGTTAACATCAACATTTCATTAATGGATGTTTTAAAGAGCCGATTTAAAGAGGAGGATGTAAAACCGGAAAGTTTTGTTAAGTTAGAAAGCAATAACGAGGcagaaactttttttaatgacTTTTATAACGACGAGAATAGTGATCAAGAAGAAAAGAAGCAATATAATTGTTCAATTTGTAATTTAGACTTTGAGGATGAAGGGTCGTTAAAGAGGCATAATCATTTAAGATCGTTACGATGTGGGGTGTGCAATAAAGATTTCTCGAATGGTTATACATTACGCCGACACATGTTAACTCATAAAAAGGGCGATTTAGATGAATCCGATCAAAAAATCGATGATGTTTTGATTGAGATGGAAAAAATCGTCCAAAAACATGATGAAATGTATCCTAATGATGTTGACGACTCTATGTTGAGGTGTGAAATTTGCAGGGAAAGTTTTGACACGAAAATAATCTTGTTAGAGCATGTTAAAGATCATTTTGGGGTGAATTGTGAGAGATGTGGGAAGTTTTATAAAGACTGCGCCTTATTGGACGTTCATTTGGAGGAATCTCATCACGTGAAAGCTGAGAGGAAATTATTTTCTTGTGATATCTGTTTAAAAGCGTTCGCGCTTCGAAAAAGTTTATTATTCCATGTGAGGGCGCATTTCGAGCGGCCTTTGTGTAATATTTGTGATAAAACGTATTACGATGTGAACAGCTTAAAGCGCCACATCATCTCAATCCATAAAAATAGCAAATTTAAGATAGATTTTGACTCGGATGAATTCGCCGATGTCGTTTTTGAGGTTGACGaaacgaatttattaaaaactttgcGAATTTacttagaaaaatttaaaatcgattgcAAAAATCAATGCGATTTTTGTAACGAAACTTTTAAAGGGGACGAGGAATTCAACGAGCATTACTTAAAATCGCATTTTTTGCGCCCTTTTTGTAAAACTTGTAATAAAAGGTTCATTAATTTGGATTGTTTAAAAAAGCACACCCTCCAAGCTCACAAAGAGGATGATCTTAACGAAATGGAggttaaaaagattaaattggAGTGTTTTTGCAACAATTCGATTTGTACTTGCAAAAATAGCTTGAAATGCCCGACTTGCGGGAAAATAATGGGGACGAAATCTTCGTTTATTCGCCATAAATTGACCCACGcaaaacgaaaaaattttatttgcgaTTTTTGCCAAAAATCGTTCCTAACAAAACTTTATCTTCAACGACACATAAACACAACTCATTTAGGGGTACCACGAAAACGAACttcaaataacatttttacCTGCGATACTTGTGGGTTAACCACGAATAATAAACACACTCTAATCCAGCATATTCGAACACACACAGGGGAACGACCGTATAAGTGCGATTTATGCGGGAAAGCTTTCGTTCAAAGCAGCACTTTGGGCACTCACAAACGGACGGTGCATTCAACGGAACGCCTTTTTACTTGCGAATATTGTAGTAAATCGTTTAACACGAAAGGATCGTTAACTAAACATATTCTCGAGGTACATATGGTCGATAAAATCGAGAAAAAGTTTTCGTGTAATTTTTGCGGGAAGAAATATCGCTTGCAAAGTCAGCTAACGTGTCATTTGAAGTGGCACAGTTCCGAGAGGCAATTTAGTTGCGATATTTGCGGGAAACCGTTTGTTGATAGGCACTCGGTGAAGAAGCACAGGGTTATACATTTTAGTGAGAAGCAACATAAATGTGAGATTTGCGGGAAAGGGTTCCATCAAAagtataatattaaaattcatatgAAGGTTCATTCGAGGGTACCTTGA
Protein Sequence: MTSACRLCLNSSSSDYRDYKSVDQKYFDVVLPEIDITMISSPILCINCVELLRAAYLFKSNCLETERLIKAYIEGVGGVNINISLMDVLKSRFKEEDVKPESFVKLESNNEAETFFNDFYNDENSDQEEKKQYNCSICNLDFEDEGSLKRHNHLRSLRCGVCNKDFSNGYTLRRHMLTHKKGDLDESDQKIDDVLIEMEKIVQKHDEMYPNDVDDSMLRCEICRESFDTKIILLEHVKDHFGVNCERCGKFYKDCALLDVHLEESHHVKAERKLFSCDICLKAFALRKSLLFHVRAHFERPLCNICDKTYYDVNSLKRHIISIHKNSKFKIDFDSDEFADVVFEVDETNLLKTLRIYLEKFKIDCKNQCDFCNETFKGDEEFNEHYLKSHFLRPFCKTCNKRFINLDCLKKHTLQAHKEDDLNEMEVKKIKLECFCNNSICTCKNSLKCPTCGKIMGTKSSFIRHKLTHAKRKNFICDFCQKSFLTKLYLQRHINTTHLGVPRKRTSNNIFTCDTCGLTTNNKHTLIQHIRTHTGERPYKCDLCGKAFVQSSTLGTHKRTVHSTERLFTCEYCSKSFNTKGSLTKHILEVHMVDKIEKKFSCNFCGKKYRLQSQLTCHLKWHSSERQFSCDICGKPFVDRHSVKKHRVIHFSEKQHKCEICGKGFHQKYNIKIHMKVHSRVP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01098680;
90% Identity: -
80% Identity: -