Basic Information

Insect: Onthophagus sagittarius
Gene Symbol: Zfx
Assembly: GCA_036711965.1
Location: JASERS010000003.1:33387824-33398518[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.028 3.5 9.7 0.2 1 23 22 45 22 45 0.97

2 26 0.0024 0.29 13.1 1.3 1 23 50 72 50 72 0.99

3 26 0.0015 0.19 13.7 1.0 1 23 81 103 81 103 0.98

4 26 0.00013 0.016 17.1 0.0 1 23 109 131 109 131 0.97

5 26 0.00039 0.048 15.6 0.8 1 23 137 159 137 159 0.96

6 26 4.1e-05 0.005 18.7 1.2 1 23 165 187 165 187 0.98

7 26 1.8 2.2e+02 4.1 0.2 3 13 195 205 193 207 0.88

8 26 0.012 1.5 10.9 0.6 2 20 217 235 216 238 0.92

9 26 7.3e-05 0.0091 17.8 4.5 3 23 245 265 244 265 0.97

10 26 0.0072 0.9 11.6 0.3 2 23 273 295 272 295 0.93

11 26 0.042 5.2 9.2 3.5 1 23 301 324 301 324 0.97

12 26 3.4 4.3e+02 3.1 7.4 1 23 329 351 329 351 0.97

13 26 0.001 0.13 14.2 0.2 3 23 362 382 360 382 0.98

14 26 8.1e-06 0.001 20.9 0.4 1 23 388 410 388 410 0.99

15 26 1.5e-05 0.0019 20.0 1.6 1 23 416 438 416 438 0.98

16 26 5.8e-06 0.00071 21.3 0.3 1 23 444 466 444 466 0.98

17 26 0.00019 0.023 16.6 1.3 3 22 474 493 472 493 0.94

18 26 0.00092 0.11 14.4 1.5 3 23 561 581 560 581 0.98

19 26 0.017 2.1 10.4 2.9 1 23 587 609 587 609 0.98

20 26 0.075 9.2 8.4 1.6 1 23 615 637 615 637 0.87

21 26 0.00032 0.04 15.8 2.4 1 23 643 666 643 666 0.98

22 26 0.0001 0.013 17.4 1.5 1 23 678 701 678 701 0.95

23 26 0.0023 0.28 13.2 1.0 3 23 712 732 711 732 0.98

24 26 7.9e-06 0.00098 20.9 0.6 1 23 738 760 738 760 0.98

25 26 5.4e-06 0.00067 21.4 0.4 1 23 766 788 766 788 0.98

26 26 0.039 4.8 9.3 0.2 1 21 794 814 794 815 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.028	3.5	9.7	0.2	1	23	22	45	22	45	0.97
2	26	0.0024	0.29	13.1	1.3	1	23	50	72	50	72	0.99
3	26	0.0015	0.19	13.7	1.0	1	23	81	103	81	103	0.98
4	26	0.00013	0.016	17.1	0.0	1	23	109	131	109	131	0.97
5	26	0.00039	0.048	15.6	0.8	1	23	137	159	137	159	0.96
6	26	4.1e-05	0.005	18.7	1.2	1	23	165	187	165	187	0.98
7	26	1.8	2.2e+02	4.1	0.2	3	13	195	205	193	207	0.88
8	26	0.012	1.5	10.9	0.6	2	20	217	235	216	238	0.92
9	26	7.3e-05	0.0091	17.8	4.5	3	23	245	265	244	265	0.97
10	26	0.0072	0.9	11.6	0.3	2	23	273	295	272	295	0.93
11	26	0.042	5.2	9.2	3.5	1	23	301	324	301	324	0.97
12	26	3.4	4.3e+02	3.1	7.4	1	23	329	351	329	351	0.97
13	26	0.001	0.13	14.2	0.2	3	23	362	382	360	382	0.98
14	26	8.1e-06	0.001	20.9	0.4	1	23	388	410	388	410	0.99
15	26	1.5e-05	0.0019	20.0	1.6	1	23	416	438	416	438	0.98
16	26	5.8e-06	0.00071	21.3	0.3	1	23	444	466	444	466	0.98
17	26	0.00019	0.023	16.6	1.3	3	22	474	493	472	493	0.94
18	26	0.00092	0.11	14.4	1.5	3	23	561	581	560	581	0.98
19	26	0.017	2.1	10.4	2.9	1	23	587	609	587	609	0.98
20	26	0.075	9.2	8.4	1.6	1	23	615	637	615	637	0.87
21	26	0.00032	0.04	15.8	2.4	1	23	643	666	643	666	0.98
22	26	0.0001	0.013	17.4	1.5	1	23	678	701	678	701	0.95
23	26	0.0023	0.28	13.2	1.0	3	23	712	732	711	732	0.98
24	26	7.9e-06	0.00098	20.9	0.6	1	23	738	760	738	760	0.98
25	26	5.4e-06	0.00067	21.4	0.4	1	23	766	788	766	788	0.98
26	26	0.039	4.8	9.3	0.2	1	21	794	814	794	815	0.94

Sequence Information

Coding Sequence: ATGCTTTCTTCAGATATAACTCTAAAAAAGCATATGATTGCGTGTCACCTCAAAGAACATCCGTTCAAATGCGATCAATGCGATAAAGGGTATTTATCAGAAGCCGCTTTagataatcataaaaaaacagCCCACGATGGAGTGGTTTATAAATGCGATCAATGCGAAAAAACATACAAATGGCCGCAAGCTTATAAAAATCACGTGAAAACACACGAAACAGGGTATATAAAGCCTGAACACGTCTGTATGATATGCTCTAAAATATTGGGATCGAAAAATTCTTTACAGGATCATTTACGTACTCATCAATCGATAAAACGTTATATGTGCGAAATTTGTGGAAAAGGAGTTACATCGTTAGAATCATTGAAAATTCACGAACGTGGTCATCGAGGAGAGAAACCTTTCGCTTGTAAACATTGTCCGAAAAAATTCGTATCAAACGCGTTACTTCGCCCTCACGAACGAATTCACACAAACGAAAAGCCTTACGTTTGCCAAACATGTAATAAAGCATTTAATCAATATGGATCTTACAAAATTCACACGAGAATTCACACGGGTGAAAGGCCATATGGTTGTCATCTTTGCGAGAAGCGATTTCCATCTCGAACAGCGAATCCCTTATCAccatcaaaagaaattaaatgttACGTCTGCAATGAAGGTTTTGAAAAAAGAGCAAAATTAAAAACGCACATGTGGAAACATAGACCAAAAAATCGATGTTGTGATGTATGTGGACGTAAATTTAAAAGCAATACCCTGTTGAACAACCATAAACGAACgcataattcacaaaaaaaaaccgTTCAATGTACACTTTgcgaaacaaaatttatatcaGAAAATAATATGAAACTACATATGACAGCGGTCCATCTTAAAGATTACCCCTTTAAATGCGATCAATGCGGTAAAGGTTATATGCAGCATCATGTTTTGGATAACCATAAGAAATCGGCTCATTTAGGGATTATTCATAAGTGTGATAAGTGCAATAGAGAATATAAATGCGTGTTTGCGTTTAGACAACATCTAAAAACGCATGAAGTGGGGTACACAAAAACGGAATACGGCTGTCcgaaatgttcaaaattattatcttcaaaaagaGCTTTAGAACGTCATATTGCTACTCACGAAGATTCAGCAAGATATGTATGTAAGTTTTGTGGAAAATCGTACGGTTCTGCAGCCTACCTAAAAATCCATGAACGCACGCATAAAGGAGAGAAACCTTTTACGTGTCAACATTGTCCGAAATCTTTTGTTTCAAACATATTGCTTAAAATGCACGAACGTATTCATACTAATGAAAGGCCGTATGTTTGTAAGATttgtaataaaacatttaatcaACTTGCACCGCTTACAATTCATACTAGAATCCATACAGGTGAGCGACCGTATGGTTGTCATCTTTGCGATCAACGATTTTCTTCCAGAACTAATTTGAACGTGCATTTAAAAaaGAAATCAAAGAAAATTGGTAAAAAGTGCGTACTGGCTCGAAaaagaaaagataataataatacttcgTACGATGACTCAACAATTCGATTAGGTGAAGTTATCATAAAAGATGAACCATTCGATATCGATTCCGATGGAATAATCATCCAAGATGAAATCACCAAGAAAGAAAATGACGAGAAAACATCTGAAGCGATCCTATGCGAAATTTGCGATCAAACATTTACCAACAACATCGAGTTCTGCTTACACACTATCACTCATAGTGAAGACGATAAATATCATTGTTATCTATGTAATTATAGGAGTGCTTCGAAATACAGCATCGAATCGCATATAAGAACCCACGATGGCACCGCTAAATATAAATGTGAAATATGCAACAAAGGTTTTGGAGTAAGCACGCATGCTTTAgaacataaatattttcatacCGGAGAGAAACCGTTTCAATGTGAAATATGCggaaaacattttatgttcTCCTGGTTCTTAGCGTCACATCGAAGATCCCAACATTGGGAAATAATAACGGGAATGCCATTAGTCAAATATGAttgtttaatttgtaataaacatTACACATCATCGACTGGATTAAAACGCCATCAAGCTAGTATTCATAATATGGGACAACGCGAAGCATCCCGTTTGTGCGATATTTGCGGTAAAAGTTTGTCtagtaaagaaaaattgaaatttcataGAAGAATTCATACCGGATTCAAACCGTACGCTTGCACGGTGTGTTCAAAAGCATttacaaaaaaagaacaattaaaagaaCACGAACGGGTGCACACCGGTGAAAAACCGTATATATGCAAATTTTGTGGAAAAGGATTTAGCCAAAGAAGTCCTTTAAGAATACATGAGCGTATACACACCGGCGAACGGCCATATAGTTGCAAAATATGTTTTAGGGGATTTGTTTCTAAAGGAGTCATGGACATTCACATGAAATCTTGTCAAGGACAGAGCCGGCAAAATTCTCGCAACACCAATAAAACATAG
Protein Sequence: MLSSDITLKKHMIACHLKEHPFKCDQCDKGYLSEAALDNHKKTAHDGVVYKCDQCEKTYKWPQAYKNHVKTHETGYIKPEHVCMICSKILGSKNSLQDHLRTHQSIKRYMCEICGKGVTSLESLKIHERGHRGEKPFACKHCPKKFVSNALLRPHERIHTNEKPYVCQTCNKAFNQYGSYKIHTRIHTGERPYGCHLCEKRFPSRTANPLSPSKEIKCYVCNEGFEKRAKLKTHMWKHRPKNRCCDVCGRKFKSNTLLNNHKRTHNSQKKTVQCTLCETKFISENNMKLHMTAVHLKDYPFKCDQCGKGYMQHHVLDNHKKSAHLGIIHKCDKCNREYKCVFAFRQHLKTHEVGYTKTEYGCPKCSKLLSSKRALERHIATHEDSARYVCKFCGKSYGSAAYLKIHERTHKGEKPFTCQHCPKSFVSNILLKMHERIHTNERPYVCKICNKTFNQLAPLTIHTRIHTGERPYGCHLCDQRFSSRTNLNVHLKKKSKKIGKKCVLARKRKDNNNTSYDDSTIRLGEVIIKDEPFDIDSDGIIIQDEITKKENDEKTSEAILCEICDQTFTNNIEFCLHTITHSEDDKYHCYLCNYRSASKYSIESHIRTHDGTAKYKCEICNKGFGVSTHALEHKYFHTGEKPFQCEICGKHFMFSWFLASHRRSQHWEIITGMPLVKYDCLICNKHYTSSTGLKRHQASIHNMGQREASRLCDICGKSLSSKEKLKFHRRIHTGFKPYACTVCSKAFTKKEQLKEHERVHTGEKPYICKFCGKGFSQRSPLRIHERIHTGERPYSCKICFRGFVSKGVMDIHMKSCQGQSRQNSRNTNKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -