Basic Information

Insect: Ontholestes murinus
Gene Symbol: Zbtb8b
Assembly: GCA_963969525.1
Location: OZ018396.1:7389330-7392575[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 4.8 1.7e+03 2.3 0.4 2 23 86 108 85 108 0.90

2 15 0.024 8.3 9.5 0.2 1 23 114 136 114 136 0.93

3 15 0.00025 0.088 15.8 0.6 1 23 142 165 142 165 0.90

4 15 2e-05 0.0069 19.2 0.4 1 23 173 196 173 196 0.96

5 15 0.074 26 8.0 0.7 1 23 202 225 202 225 0.95

6 15 0.036 12 9.0 0.6 1 21 231 251 231 252 0.93

7 15 0.00011 0.038 16.9 0.1 2 23 285 307 285 307 0.96

8 15 0.00013 0.045 16.7 0.6 1 23 313 335 313 335 0.96

9 15 0.00088 0.31 14.0 2.7 1 23 341 363 341 363 0.96

10 15 4.5e-06 0.0016 21.3 1.2 1 20 369 388 369 389 0.96

11 15 1.3e-05 0.0047 19.8 1.1 1 23 400 422 400 422 0.99

12 15 0.00015 0.051 16.5 2.7 1 23 428 450 428 450 0.97

13 15 0.0001 0.035 17.0 2.1 1 23 456 479 456 479 0.96

14 15 0.00018 0.064 16.2 1.1 1 23 493 515 493 515 0.97

15 15 1.6e-06 0.00056 22.7 0.8 1 23 521 544 521 544 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	4.8	1.7e+03	2.3	0.4	2	23	86	108	85	108	0.90
2	15	0.024	8.3	9.5	0.2	1	23	114	136	114	136	0.93
3	15	0.00025	0.088	15.8	0.6	1	23	142	165	142	165	0.90
4	15	2e-05	0.0069	19.2	0.4	1	23	173	196	173	196	0.96
5	15	0.074	26	8.0	0.7	1	23	202	225	202	225	0.95
6	15	0.036	12	9.0	0.6	1	21	231	251	231	252	0.93
7	15	0.00011	0.038	16.9	0.1	2	23	285	307	285	307	0.96
8	15	0.00013	0.045	16.7	0.6	1	23	313	335	313	335	0.96
9	15	0.00088	0.31	14.0	2.7	1	23	341	363	341	363	0.96
10	15	4.5e-06	0.0016	21.3	1.2	1	20	369	388	369	389	0.96
11	15	1.3e-05	0.0047	19.8	1.1	1	23	400	422	400	422	0.99
12	15	0.00015	0.051	16.5	2.7	1	23	428	450	428	450	0.97
13	15	0.0001	0.035	17.0	2.1	1	23	456	479	456	479	0.96
14	15	0.00018	0.064	16.2	1.1	1	23	493	515	493	515	0.97
15	15	1.6e-06	0.00056	22.7	0.8	1	23	521	544	521	544	0.98

Sequence Information

Coding Sequence: ATGGAAGAAGCCCTAATATCTACCTGTTTAGTTTGCCTGGGGGATCAAAACTTGGTAAACATTACGGAATCGGATGGGGAGAATGTCGATTGGAAGACCAAGTTAAAATTCTGTTTACCCGAACTGgattGGAACATCATTTGTTTCTTGTGTAAGACGTGCGCGGGTGAACTCGACGTCATCTGCAGCTTCAGGAACAAATGCCTGTCTTCCTACCTCTGCAAACGTGACGTCAGCCATGATAAAGTACAAGTCAGGTGCAAGCTCTGTTTGGACATCTTCGACTTTCGCAACGATCTCACCGAACACAATCTGCGCGAGCATTACGTACAAACACCGCACGACTGCCTGCTGTGCCCGAACAGTTTCAACACGCAACCGGAGCTGGTGGAGCACGAAAACGGCCACTATCTCCTGCAGAGGTTTTACTGCGACGACTGCAAGACGAGCTACTCGAGCGCGGACGAGCTATCGAATCACGTGGCCTTTAAACATTGCAAAACGGAGGAGTGGAGCCACCCTTGTCCACACTGCGGAATCGTGTTTCCAACGAAGAATTATTTAGATGAGCATGTGATGACCGTACACTGCGATAGCGTGAGTTTTTCGTGCTTCCACTGCGGTGTGAAATTATTGGATAAGTCTTTGCTGGTGGAGCATATTAAAGAAATGCATAAGGTGAAAAAGGAGTACATGTGTTTGTCTTGTAATTCAGTGTATAGCACGaagaaaaaattggaaatccATAGGAGTACGTGTGGCGTTAAGGACGATTTTTGCGAACGGGACGTTTCCGATTCGGACGAGGTTAAACCGAAACGCGGTAGGAAGCCGAAAGAAAAGGTTTTGAATGAGTGTGAAATATGCGGGGTTAATTTTTCAGCTAGATACTTACTAACCAGGCACGTTAGGAATGTGCACGCCACGGAAAAGATTCATAATTGTGATGAGTGCGGACAGAAGTTTGCTTCCGCCGTGTATTTAGCAGCGCATAAGAAGTATCATTCGGGAAGTAGACCGCACATTTGCTCGTTCTGTGGGAAGGGTTATATAACTACAAGCGACTTGTATCATCATGAAAAAATACACGCGAACAAGCGGGCGTATAAATGCGACAAATGCCCGAAAGCTTTCAACACATCCAGTGACTTACACAAGCACAGGATTTGCGTACACGTGGACAGATCGTTGTGGAAATACGTGTGTACGTATTGCGAACGGAGatttccattaaaaacaaaCCTGGATACTCATATTAAGACCCACACGGGGGAGAGGAATTACGCTTGCCATTTATGTGACCGACGGTGTATAAATCAATCAGTCTTGCAAAGGCACATCGATTCGCACTCGAATATTTGCTCGTTCACTTGCTCACAGTGCGGACAGGATTATAAGCACAAAAAATCGTTGAATATCCATTTGGCGAAAGTGCACGGGATCGGTGACGTGAAAATACCGGAACcagttaaaaaattcttctgtCCGTTCTGTCCAAGGGCGTATTTTGCAAACAACAAGCTGCAGAAACACATCAGGACGCACACTGGCGAACGACCTTTTTCCTGCAACATATGCGCGAAATCTTTTATTGATAAATCGTACGTAAAACAACATATGAAAACAGCCCATAATATCGTGGACTaa
Protein Sequence: MEEALISTCLVCLGDQNLVNITESDGENVDWKTKLKFCLPELDWNIICFLCKTCAGELDVICSFRNKCLSSYLCKRDVSHDKVQVRCKLCLDIFDFRNDLTEHNLREHYVQTPHDCLLCPNSFNTQPELVEHENGHYLLQRFYCDDCKTSYSSADELSNHVAFKHCKTEEWSHPCPHCGIVFPTKNYLDEHVMTVHCDSVSFSCFHCGVKLLDKSLLVEHIKEMHKVKKEYMCLSCNSVYSTKKKLEIHRSTCGVKDDFCERDVSDSDEVKPKRGRKPKEKVLNECEICGVNFSARYLLTRHVRNVHATEKIHNCDECGQKFASAVYLAAHKKYHSGSRPHICSFCGKGYITTSDLYHHEKIHANKRAYKCDKCPKAFNTSSDLHKHRICVHVDRSLWKYVCTYCERRFPLKTNLDTHIKTHTGERNYACHLCDRRCINQSVLQRHIDSHSNICSFTCSQCGQDYKHKKSLNIHLAKVHGIGDVKIPEPVKKFFCPFCPRAYFANNKLQKHIRTHTGERPFSCNICAKSFIDKSYVKQHMKTAHNIVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -