Omur038402.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ontholestes murinus
Gene Symbol
ZEB2
Assembly
GCA_963969525.1
Location
OZ018390.1:15205122-15209436[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0011 0.38 13.8 0.8 1 23 159 181 159 181 0.95
2 16 0.61 2.1e+02 5.1 1.8 1 23 189 212 189 212 0.90
3 16 6e-07 0.00021 24.0 0.7 1 23 218 240 218 240 0.99
4 16 1.3e-06 0.00046 22.9 3.2 1 23 246 269 246 269 0.97
5 16 1.7e-05 0.006 19.4 3.3 1 23 281 303 281 303 0.96
6 16 0.00017 0.059 16.3 2.9 1 23 308 330 308 330 0.95
7 16 2.3e-06 0.00082 22.1 0.2 1 23 336 358 336 358 0.99
8 16 1.4e-07 4.9e-05 26.0 3.2 1 23 364 386 364 386 0.99
9 16 2.4e-07 8.4e-05 25.3 0.3 1 23 392 414 392 414 0.99
10 16 0.13 46 7.2 0.3 1 14 420 433 420 434 0.92
11 16 0.11 38 7.5 4.4 1 23 586 608 586 608 0.99
12 16 6.5e-07 0.00023 23.9 0.6 1 23 614 636 614 636 0.97
13 16 0.013 4.7 10.3 0.1 2 23 656 678 655 678 0.91
14 16 1.2e-06 0.00041 23.1 5.6 1 23 694 716 694 716 0.98
15 16 1.8e-07 6.3e-05 25.7 0.6 1 23 722 744 722 744 0.98
16 16 8e-07 0.00028 23.6 0.6 1 23 750 772 750 772 0.99

Sequence Information

Coding Sequence
ATGGACAAGAGGGTAAACATCTTCAATTCGACAATTTCGGCCTCGCTGGAAAGGTTGCTGAGGGCCAAAAAAGAAGACGAATATGTTAATTTCGATGATGTGTGTCGGTCATGTTTATCATCGAAAAATGAGTTAACAAACATTCATCAAATCTCTCTGGGGGGGTTAAGTGTTGCAGAAGTTTTTGACCAATACATGGCAATAAAGgtaGAGGATCAAGATGATTTACCTCAAAATCTCTGCACGATGTGCCTTTATGAGGTATGTAGAGTTTACCTGTTCATAAACAATTGCAGAGAAGCTGATACTAAGCTCAAAGAGCTGGTCTTAAAAGTCCAGAGCGGAGATGAGGAAGTCTACCATGAAAGTATAGTCACCACGGAAAACAATGACACGACTGGATGGAATATGCAAGATAACACTAATGACTTGCTACAAATGGGTCCAATTAAAGTGACAGAGCCAGGACCcccatttatttgtaataactgCTCCGAGAGCTTCAGCACCCTCAGCGAAATCAAGATGCACAGGACACTGCATAAGCATTACATCATGCGACAGTACCTCTGCAGAATTTGCAATCCCAGTAAGGTCTACAGTTATCGGCATTGGAGGAATCATATGCGGGTGCATACTGGGGAAAAGCCGTATGAGTGTCACATTTGCGGGAAGAAATTTAGTGTTCCTGGCAACCGGGAACGACATATTTTAACTCATACTGGAGAAAAGCCTTACAAGTGTGATCAATGTGATAaagcatTTAGTCAATCTACAAATTTGAAACATCATAAGCTTCGCGCACACATGGGTCAGAAATTGGAGAGAGAAAAGGGCCACTTTGAATGCAAGCACTGTCAAAAGGTGTTTTCAACAAGGGGCTCTTTAGCACACCACACAGTTATCCACTATGATAAGAAATTCCTATGCAACGAGTGTGGCAAGTCATTCCActacaaaatacaatttaacatGCACATGGATTCACACAGAGGCATCCGCCGCTACAAATGTAACATATGCGATAAAGCATTTGCAAGGCCCATTTCGTTGGGTCTTCACAAGCGCACCCATACTGGGCACAAACCGTACGAATGTAGATATTGTGATAAGCGATTTTCTCAGAAAGCTCATTTAGTCAGCCATATAAGGACACATACTGGTGAGAGGCCGTATTCTTGCCCCTACTGCGAGAAGACGTTTGCTCTGAATGGCAATCTCACTGTTCACATTAGAAAACACACTGGAGAAAATCCATACGTGTGTGATATTTGCAGTAAAGGTTTTCCTGATTCATCTAgaaATGATGAAGATGAAtcagtaataaattatgaaattaaagaagaacGACAAGAATCTGAAGAAGAGACTAATGATTATGAATATAATACTACAGCCGAAGAAGAGGAAGTTGAGAACAATGATGAAGAGTCTGAAActaatgaatattataaaaaagaagaCCTGAATGAAATGGAAGAGAACATAGAAGAATATGAAGAAGATGTAAATCAAAAAGAAGATAGTGTAGATCTGTTTAAATTAGGCCCAATCAGGGTACCCGAAGTTGGGCCGCCCTTTACTTGCTATTGTGGGGATGAATATGGAACGTTGGAGGAGCTTAAAGAGCACAGAAGTGAGCGAAAACATACCAACAACATCAAGCGGTATTTATGTAGAATTTGCAGCCCTAGCAGATTGTACAGCTACAAGTCTTGGTTTAACCACATGAAGAGTCATACAAATGATGAAGTCTATCAGTGCGAGCTTTGTGGTAGAATATCTAAGTCAGTCCATAATCACTATAGGCATTTAAGGTCACATAATGGAGAGAAAccttttatttgtgaaatttgtggaaaatcaTTCAGTCGTTCGACAGGATTAAATCAACACAGATTGAATCACGAACGTGAAAATGATGAATTGGAGAAGAACAATTGCAGAAAAACCAGGGTTGTACAATCCTGTGATAAATGTGATATCGTTTTTTCTGGGACAATTGCTTATAACAAACATATGTTTGATGTTCATGCTTCCTTGAAAACACACCTTTTAGTGCACAGTGGGAAGAAAGAGTTTAAATGCCATATATGTGATAAATCTTTTGTGCAAAAAACCCATTTGATAACCCACTACAAAGTTCACACTGGTGAAAAGCCTTTTGAATGCCCGTACTGTGGAAAGAGGTTTGCAATGAATGGAAATTTGACTGTTCACAAGAGGAAACATACTGGAGAGAAGCCatatgtttgtaatatatgtgAAAGGGGTTTTTATGATTCTAGTAGTATGAAAGCGCACATGAGGAAAcacttttag
Protein Sequence
MDKRVNIFNSTISASLERLLRAKKEDEYVNFDDVCRSCLSSKNELTNIHQISLGGLSVAEVFDQYMAIKVEDQDDLPQNLCTMCLYEVCRVYLFINNCREADTKLKELVLKVQSGDEEVYHESIVTTENNDTTGWNMQDNTNDLLQMGPIKVTEPGPPFICNNCSESFSTLSEIKMHRTLHKHYIMRQYLCRICNPSKVYSYRHWRNHMRVHTGEKPYECHICGKKFSVPGNRERHILTHTGEKPYKCDQCDKAFSQSTNLKHHKLRAHMGQKLEREKGHFECKHCQKVFSTRGSLAHHTVIHYDKKFLCNECGKSFHYKIQFNMHMDSHRGIRRYKCNICDKAFARPISLGLHKRTHTGHKPYECRYCDKRFSQKAHLVSHIRTHTGERPYSCPYCEKTFALNGNLTVHIRKHTGENPYVCDICSKGFPDSSRNDEDESVINYEIKEERQESEEETNDYEYNTTAEEEEVENNDEESETNEYYKKEDLNEMEENIEEYEEDVNQKEDSVDLFKLGPIRVPEVGPPFTCYCGDEYGTLEELKEHRSERKHTNNIKRYLCRICSPSRLYSYKSWFNHMKSHTNDEVYQCELCGRISKSVHNHYRHLRSHNGEKPFICEICGKSFSRSTGLNQHRLNHERENDELEKNNCRKTRVVQSCDKCDIVFSGTIAYNKHMFDVHASLKTHLLVHSGKKEFKCHICDKSFVQKTHLITHYKVHTGEKPFECPYCGKRFAMNGNLTVHKRKHTGEKPYVCNICERGFYDSSSMKAHMRKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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