Basic Information

Insect: Oncopeltus fasciatus
Gene Symbol: lola
Assembly: None
Location: Scaffold114:187328-687731[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00082 0.051 14.1 1.0 1 21 30 50 30 51 0.96

2 26 0.014 0.86 10.3 1.4 1 21 71 91 71 92 0.96

3 26 3.3 2e+02 2.8 1.8 1 16 100 115 100 117 0.88

4 26 0.0069 0.43 11.2 0.2 1 21 127 147 127 148 0.95

5 26 0.049 3.1 8.5 1.8 1 21 167 187 167 188 0.94

6 26 2.9 1.8e+02 3.0 0.2 1 11 196 206 196 211 0.80

7 26 0.2 12 6.6 2.8 1 21 307 327 307 328 0.92

8 26 2.7 1.6e+02 3.1 2.2 1 13 336 348 336 350 0.86

9 26 0.0059 0.36 11.4 0.5 1 21 480 500 480 501 0.95

10 26 0.0012 0.074 13.6 3.3 1 23 509 531 509 531 0.95

11 26 9.3e-05 0.0058 17.1 2.1 1 21 555 575 555 576 0.97

12 26 1.3 83 4.0 1.2 1 13 584 596 584 597 0.89

13 26 0.02 1.3 9.7 3.1 1 21 603 623 603 624 0.95

14 26 0.0018 0.11 13.1 0.7 3 23 634 655 633 655 0.93

15 26 0.0071 0.44 11.2 0.8 5 21 669 685 668 686 0.93

16 26 1.1 71 4.2 1.5 1 15 694 708 694 710 0.87

17 26 0.048 2.9 8.6 0.4 6 21 713 728 711 729 0.93

18 26 0.003 0.18 12.4 0.6 1 23 737 760 737 760 0.95

19 26 0.012 0.77 10.4 1.4 1 21 801 821 801 822 0.90

20 26 0.043 2.6 8.7 2.4 1 23 830 853 830 853 0.94

21 26 0.00021 0.013 16.0 1.7 1 21 869 889 869 890 0.96

22 26 0.0012 0.072 13.7 3.6 1 23 898 921 898 921 0.94

23 26 7.6e-05 0.0047 17.4 2.6 2 22 950 970 949 970 0.95

24 26 0.002 0.12 12.9 1.8 1 23 979 1002 979 1002 0.93

25 26 0.00029 0.018 15.5 1.6 1 21 1268 1288 1268 1289 0.96

26 26 4.1e-05 0.0025 18.2 1.3 1 23 1297 1320 1297 1320 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00082	0.051	14.1	1.0	1	21	30	50	30	51	0.96
2	26	0.014	0.86	10.3	1.4	1	21	71	91	71	92	0.96
3	26	3.3	2e+02	2.8	1.8	1	16	100	115	100	117	0.88
4	26	0.0069	0.43	11.2	0.2	1	21	127	147	127	148	0.95
5	26	0.049	3.1	8.5	1.8	1	21	167	187	167	188	0.94
6	26	2.9	1.8e+02	3.0	0.2	1	11	196	206	196	211	0.80
7	26	0.2	12	6.6	2.8	1	21	307	327	307	328	0.92
8	26	2.7	1.6e+02	3.1	2.2	1	13	336	348	336	350	0.86
9	26	0.0059	0.36	11.4	0.5	1	21	480	500	480	501	0.95
10	26	0.0012	0.074	13.6	3.3	1	23	509	531	509	531	0.95
11	26	9.3e-05	0.0058	17.1	2.1	1	21	555	575	555	576	0.97
12	26	1.3	83	4.0	1.2	1	13	584	596	584	597	0.89
13	26	0.02	1.3	9.7	3.1	1	21	603	623	603	624	0.95
14	26	0.0018	0.11	13.1	0.7	3	23	634	655	633	655	0.93
15	26	0.0071	0.44	11.2	0.8	5	21	669	685	668	686	0.93
16	26	1.1	71	4.2	1.5	1	15	694	708	694	710	0.87
17	26	0.048	2.9	8.6	0.4	6	21	713	728	711	729	0.93
18	26	0.003	0.18	12.4	0.6	1	23	737	760	737	760	0.95
19	26	0.012	0.77	10.4	1.4	1	21	801	821	801	822	0.90
20	26	0.043	2.6	8.7	2.4	1	23	830	853	830	853	0.94
21	26	0.00021	0.013	16.0	1.7	1	21	869	889	869	890	0.96
22	26	0.0012	0.072	13.7	3.6	1	23	898	921	898	921	0.94
23	26	7.6e-05	0.0047	17.4	2.6	2	22	950	970	949	970	0.95
24	26	0.002	0.12	12.9	1.8	1	23	979	1002	979	1002	0.93
25	26	0.00029	0.018	15.5	1.6	1	21	1268	1288	1268	1289	0.96
26	26	4.1e-05	0.0025	18.2	1.3	1	23	1297	1320	1297	1320	0.96

Sequence Information

Coding Sequence: ATGGAGGTTTTCCCCAGAGAACGGGAGGCACTCGGTGAACGAACTGGGGACTTCGTGAAGCGAGACGGAGCTTACGGTATGAAGCTTTATCATTGTCAGGGATGTAATCGCTCATACATGAGAAAAGGAGCACTTAATACACACATTAAATTTGAGTGTGAAGGCTTCAGTGTTCTTATGGTTAGATCAGGAGATGAACTAACACCAATTTATGAATGCTCAACTTGCCAAAGGAATTACAAAACTAAAACTGGAATCAAACAGCATCTTCGGTTTGAATGTGGAAAAGAACCCCAGTTTAATTGTCCTCAGTGTCCTTATAAATCTAAGCATAAAAGTGGATATTTTAATATCAAATCTGAATCTTTTAATGTGATTTATGACTGCCCAAATTGTGAAAGAAAATATCGAACCAAAGCTGGCATTAATCAACATATAAAATATGAATGTGTTGGAAACATTGAAAATATTGCAAAAGGGCATCCTACTCAAAAGAATTATGAATGTCTTGAATGCAATAGGCATTATAAATCAAGACAAGGTCTCTATGTGCATAAGAAATATGAATGTGGAAAAGACCCTCAATTTCAGTGTCCTCATTGTCCCTTCAAAGCAAGACAAAAAATACCTCTTGATAGTAAGTACTACTTGTATGTAACTTTTGTGGCCGAGTGTTTTGCCACAAAAGGGCTGTTTTTCATCATCAAAAGTATGAATGTGGTGTTTCACGTTTACAATTTGATAAGGGATTACATGTCTGCCTTGTTTGTTTCAAACAATACAAGTACCCACAGGGTCTTCAACGTCACCAGAAGTATGAATGTGGAAAAGAACCACAATTCCAGTGTCCCTACTGTCCTCACAGAACAAAAATTAAAAGTTACATTGCAAGTTGGAAATAACTATAACGGGCAAAAATTTGTTTGTGAAAATTGCTTCAGGGTCTACAGGCACAAAGGCACTCTAAAATTTCATCAGAAATTTGAGTGTGGCAAGGAACCTCAGTTTCAATGTCCTTATTGTCACTATAAAGCTAAGCGGAAGACCAAAAAATTCTATTCAAACCCACTTAAACAGATACTTTCTTTAGGAGATTATGGAGGCTATTTTGACCCTTGTAGAACTATTACACTTGGATTGGAAGTCAACGAGTCCAAGACTTTATATATATATGCGTCTACAAGCAAAGAAGTGAGACTGGAGGAGATAGTCCAATTTGAACTTATTCATTTCAAGAACGATCAGAACTTAAGGCGGGATACTATTATTTATGTACTGATTGTGGAAAACAATATCGTCAACAAGGAAGTCTGTGGAATCATAAGAAATATGCATGCGGTAAACCTCCAGGTTTCCATTGTCCCCATTGCCCTCATAAGACAACATATGTTTGCATTAAAGTTATATTTTTATATTGCAGTTTTTCCTGGAAAAAAATTTAAGTGCCCTAACTGCACAAGAAGTTACACAGCCTCTAATGGACTTTCCCAACATTTGAAATATGAGTGTCTCAAGGATCCCCAGTTCTTATGTCCTCATTGTCAGTTTAAAACTAAAAGAAGAAGCACCCTTAAAGTTCATATTGCGAAACATCTTGATATTAAGTTCTTTAATAACATTATGAAAGTTTATTTTATCAATTTTGTCATTACTTCTAGGCTGTACAAATGTCAGAATTGTAATCGATCATATTCTCATAAAGGCTCCTTAAGTCAACATTTAAGACTTGAGTGTGGAAAGGAGCCTTCACATCAGTGTCCTTATTGCCCTTATAAAACTAAAAGACCAACAATTATTGCTAAAAAATTTCGATGCATGAAATGCTTTCGATCTTATACTCATAAAAGATCACTCAGTTTGCACCTCAAATGGGAGTGTGGAAAAGAACCTATGAATATTTGTAAATACTGTGGCTACAGAAGTAAAAGGGTGGGTAATTTAAAGTCACATATATATTTAAAACACTTTGAAGATCCGTCTAAAATGGGAAGAATATTCATGTGTGACTGTGGGAAAGTTTATAAGCAAAAAACAAGCCTCTATAAGCACAGGAAATATGAGTGTGGGAAAGAACCTCAGTTCCAGTGTCCTCATTGCTCCTATAAATCGAAACAAAAAGGTTTATTTTCATGTTTATGTGGTCGAAGTTACAAACAAGCTGCTAGTCTCTATAAGCACAGGAAATATGAATGTGGAAAAGAACCTCAGTTTCAGTGTCCCCACTGCCCTTATAAATCAAAACAGAAAGCTCCTTTGCTGTCTCATATTGTCATCAAACACCGTAGCTATGAACTTAAAATGTTTTTTGCTTATCCTTTACTATTGTATTTTATATATATATATATATATGTGTGTGTGTGTGTATTAATTGAATATTATTTTATTTCAGGTTTCCAGGTATTTAACTGTATTAAATGCCCCAGGAAATATCGCTACAAAGATTCTCTGACCAGACATCTTAAATATGAATGTGGAGTTGAACCAAAATTCCAATGTCGCTATTGCCCTTACAAAGCCAAACAAAAGTCATCAGTAAAATCTCATACCTACATAAAACATTTTAATAAACCTATGCTAAGAATTGGTTTTAAAATGCCAAACCGTCATAAATGTCAGGTTTGTGGGTCATCTTATAAGCAGAAAGATACACTTATTCGTCACCAAAAGTATGAATGTGGCAAAGAACCACAATTCCAGTGCCCTCATTGCCCATATAGAGCTAAAAGGAAGGACCACTTGACTTCTCATTTTGCTGTCAAACATGCCACATTACCAACATTGTTTTTGATCACTTTTTTTTTTCAGGATACAGATGTGTTAATTGTGGAAAAAGATATTCCTTTAAAACAGTGCACAAGATGTAATAAGAAGTTTTCACTTAAAGGAAATCTTCGTCGCCATCAGAGAAGTGAATGTGGCTTTAAAGTATTTAAACATATATGCTCTTATTGCAATTATAAATCAACAAGGAGTGACACTTTAAAAATCCACATTGCTCTTAAACATAACAGTGCAATACAAATTTTGTCTTATAAAATATATTTTAAAGTTCTCGAAAATTTAGAAGCCTTGAATCATTTTCAGTTATTCCTTTTTAAAATAATATCCTTTGATATGTCGGCAGACCAGCACTTCCGTTTGAAGTGGAATAATCATCAAGATACTCTTATTTCGCTATTTTCTTCTTTATTGGACTCTAATACATTCGTAGACTGTACTCTTGCTGCTGGGGGGAAACAGTTAAAAGTGCATAAAATGATTCTATCTGCATGCAGTCCTTATTTTAAGGAAATTTTATTGGAACACAGTAACACTCATCCCATTATCATAATTAACAGTATCCAGTTTCCAGAACTTGTAGCTATTGTTGAGTTTATGTATCGTGGTGAAGTAAATGTCACACAGGACCAATTATCTGTATTCCTTAAAGCAGCGAAAACACTTCAGGTAAAGGGCTTGACAAATGAGACTGATAACCTGGAAGAAGTTGTTAAAGAAAGCCAAAGTGATTATAGCGGTTATATAAGTTCTGGTGATGAACTACCTATGAAAAGTGAAGAAAAAGATGACGATTCACTCTCTTTACCTGGACCCTCAACTGCATCCTGTAACTCTGGAGGATATGTATTGTCAGATCATACACCAGTTTACCAAAATAGTGAAGAATTTCAAGGATCAAGTTTCTTAGGATTATTACCCCAAAGATATGAAGAAATGAGTTTAGCTCCTGGCGGAGGAATTCCACCTATAAATAAGATGATTCAGTTAAGAAGACCTAATGCTACTGAAAGAGATGCATCTTTTCGGTGTGATGAGTGCAATAAATTTTATCGTTCAAAGACTTCTTTAAATCTTCATAAAAGATGGGAATGCGGGAAGGAACCCAAATTTGCCTGCCCTTATTGTGATAAACGAACTCACCAAAAGGGAAATTTGAAAGTACACATAATTTCTCGACATCGAGATCGGCTTCAATCAGAGAAAACCACATAA
Protein Sequence: MEVFPREREALGERTGDFVKRDGAYGMKLYHCQGCNRSYMRKGALNTHIKFECEGFSVLMVRSGDELTPIYECSTCQRNYKTKTGIKQHLRFECGKEPQFNCPQCPYKSKHKSGYFNIKSESFNVIYDCPNCERKYRTKAGINQHIKYECVGNIENIAKGHPTQKNYECLECNRHYKSRQGLYVHKKYECGKDPQFQCPHCPFKARQKIPLDSKYYLYVTFVAECFATKGLFFIIKSMNVVFHVYNLIRDYMSALFVSNNTSTHRVFNVTRSMNVEKNHNSSVPTVLTEQKLKVTLQVGNNYNGQKFVCENCFRVYRHKGTLKFHQKFECGKEPQFQCPYCHYKAKRKTKKFYSNPLKQILSLGDYGGYFDPCRTITLGLEVNESKTLYIYASTSKEVRLEEIVQFELIHFKNDQNLRRDTIIYVLIVENNIVNKEVCGIIRNMHAVNLQVSIVPIALIRQHMFALKLYFYIAVFPGKKFKCPNCTRSYTASNGLSQHLKYECLKDPQFLCPHCQFKTKRRSTLKVHIAKHLDIKFFNNIMKVYFINFVITSRLYKCQNCNRSYSHKGSLSQHLRLECGKEPSHQCPYCPYKTKRPTIIAKKFRCMKCFRSYTHKRSLSLHLKWECGKEPMNICKYCGYRSKRVGNLKSHIYLKHFEDPSKMGRIFMCDCGKVYKQKTSLYKHRKYECGKEPQFQCPHCSYKSKQKGLFSCLCGRSYKQAASLYKHRKYECGKEPQFQCPHCPYKSKQKAPLLSHIVIKHRSYELKMFFAYPLLLYFIYIYIYVCVCVLIEYYFISGFQVFNCIKCPRKYRYKDSLTRHLKYECGVEPKFQCRYCPYKAKQKSSVKSHTYIKHFNKPMLRIGFKMPNRHKCQVCGSSYKQKDTLIRHQKYECGKEPQFQCPHCPYRAKRKDHLTSHFAVKHATLPTLFLITFFFQDTDVLIVEKDIPLKQCTRCNKKFSLKGNLRRHQRSECGFKVFKHICSYCNYKSTRSDTLKIHIALKHNSAIQILSYKIYFKVLENLEALNHFQLFLFKIISFDMSADQHFRLKWNNHQDTLISLFSSLLDSNTFVDCTLAAGGKQLKVHKMILSACSPYFKEILLEHSNTHPIIIINSIQFPELVAIVEFMYRGEVNVTQDQLSVFLKAAKTLQVKGLTNETDNLEEVVKESQSDYSGYISSGDELPMKSEEKDDDSLSLPGPSTASCNSGGYVLSDHTPVYQNSEEFQGSSFLGLLPQRYEEMSLAPGGGIPPINKMIQLRRPNATERDASFRCDECNKFYRSKTSLNLHKRWECGKEPKFACPYCDKRTHQKGNLKVHIISRHRDRLQSEKTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01095914;
90% Identity: iTF_01095914;
80% Identity: iTF_01095914;