Basic Information

Gene Symbol
ZIPIC
Assembly
GCA_963082905.1
Location
OY720415.1:4871211-4891826[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.28 25 6.5 0.9 1 19 190 208 190 213 0.89
2 18 0.0094 0.85 11.1 0.4 1 23 219 241 219 241 0.98
3 18 0.024 2.1 9.9 5.2 1 23 245 268 245 268 0.97
4 18 0.017 1.5 10.4 1.7 1 23 272 295 272 295 0.96
5 18 0.0018 0.16 13.4 2.9 1 23 298 321 298 321 0.98
6 18 5.3 4.8e+02 2.5 0.5 1 23 324 347 324 347 0.95
7 18 0.33 30 6.3 0.1 3 20 355 372 354 374 0.92
8 18 0.00076 0.069 14.6 0.1 2 23 387 409 386 409 0.94
9 18 5.5 5e+02 2.4 0.7 1 9 415 423 415 423 0.92
10 18 1.1 96 4.7 0.5 9 23 635 650 633 650 0.92
11 18 0.00037 0.034 15.5 0.7 3 23 661 681 660 681 0.97
12 18 0.0027 0.24 12.8 0.2 1 23 687 710 687 711 0.94
13 18 5.3 4.8e+02 2.5 0.5 1 23 723 746 723 746 0.95
14 18 0.33 30 6.3 0.1 3 20 754 771 753 773 0.92
15 18 0.00076 0.069 14.6 0.1 2 23 786 808 785 808 0.94
16 18 1.7e-06 0.00016 22.9 0.7 1 23 814 837 814 837 0.98
17 18 0.00037 0.034 15.5 0.7 3 23 848 868 847 868 0.97
18 18 0.0027 0.24 12.8 0.2 1 23 874 897 874 898 0.94

Sequence Information

Coding Sequence
ATGGACGAAACCGAAATAAAGTATGAATTCCCTAACTACGAGAACCAATGCAGTGTCTGCCTTAGCGTTGGAAGAAAATTATCCCTTTTAGGAGAATATATCGGTGTTTTTAAAAGCATTACTTCAGACGTTCGAAATCATAGCCAGACACCATTAGAAGATATAAAACTATGTTGGGAGTGTAATGCATTTCTGCGGAGGGCCAGTATATTCCAGCAGCAAGTCAGCAAAGCTAATGAAATGCTTCAATTGAGACAGtcctACCTCTATGGTACACAGTCCAGCCTTACAACAATAATACTAAATGATTCACATCCTCACACAATTTATGTAAATGATTTAAATGTAAAAGTACAGCCGGAAACAAAAATATGTGACAATaacagtgatgatgatgaaataaatgataattgtgAGTTTGGTGATGACTGTACTAAAACTGAAGAAGTGACGAAGGAAAGCACAGAATATACTAGACAATGTTTTAGAAGAGTACAGATAGATGATGAAGAGTTACGGTGTTTACTGAAGAGTGAAAGAGAGGGTGTATATTTTAAGTCGAAGAAGTTTAAATGTGATAGCTGTATTTTGGCGTTTTCGAGTCAAGAAATGTTGGAGAAACATGATAAGAAGTTTCATTGTAAGttaacgaAGTATACCTGTGATATTTGTACCTCAAGAATCTCGAGCAAACGCCTTTTGTCTGAACATATACGAGGCCATTACAATAAGTATGTGTGCACACTGTGCGACTTCACGTGTTACGACAAGTCGCAAACAAAATCGCATCAACAGAAAAGACACAGAAAAGTGTTTCAGTGTCTGAAATGTGAATTGAAGTTTGGGAGTCGTTGGGAATTCTTTAAGCATTACAAGGAATGGCATGAGAAGTTTGTCTGTGACTTCTGCGGGATCAGCTTCAAGATGAGATACTGCATCAAAGATCAtatcagAAAACAGCACTCCCCCTTCGAATGCAAGCCGTGCAACAAGCGCTGGGCGCGCTACAACGGTCTCTGGCTGCACAACAAGACGTCTCACGGCGCGCACAAGGCCGCGTACTGCGTGGAGTGTGACAAGCAGTACCGGGACGTGTACCGATACCGCTGGCACCTCGCTAACAGCGCCAGACACTCGCAGCACAGGAAACATAGGATTCCCTGTCCCGGTTGTGACAAGATCTTCTCGAAGAACATCTACATGAAAGACCACTATAACCTCGTTCACCTCAAGTTTTACAAGTATCGATGTGAACAATGCGATAAGGTACCGTGCGCCACCGGTCAATGGGACAAGGGTATTTCAGTGGGAGGTCGGAAGATATCTAACTTAAGATATGCCGACGACACTACTCTTCTCACACAAACAAGAGAAGACATGGAACACTTGCTGACCCGTCTAGAGACAACAAGCCTCTCCTTCGGACTAACGATCAACAGAGACAAGACCAAGATGATGATCGTGGACCGAGCTGAACTAAACCATCCTGACATCTCTATGGTTGGCAACTGTGAGGTTGTCCAATCTTATGTGTACCTCGGTTCCACTATCACAAACACTGGAGGATGTGAAGACGAGATTCGAAGGAGATGTGCTATCACACGATCTGCCGTTGACAAGCTTAAAAGAGTCTGGTGCAACCGTAATATTACCAAAGCCACAAAAGTCCGCCTAATGAGAAGCCTAGTCTTCCCGATTTTCCTGTACGGCGCAGAAACGTGGACGGTTCGCCTCAAAGACCGACGCAAAATCGATGCACTGGAGATGTGGTGCTGGCGGCGACTGCTGCGGATTCCCTGGACAGCGTTTAGGACCAATGTTTCGATCCTGGAGGAGCTAAAAGTCAAGCAGAGATTATCGTCGACTGTGCAAACACGAATTATCCAATATTTCGGCCACGTGAACTTCATTCGTAACGCTGACTTGGTGAAGCATACTCGCCGAGTCCACGAGGGCATACTACCGCCCAAGAACAAGATATGTTACATGTGCGGCAGGGGATTTTCTaCCAACAAGATTCTGACCAACCATTTACGAACACACACAGGAGAGAAGCCCTTTGCCTGTTCTTTATGCAACGCGCGCTTCGCACAGAGTACAGCTTTGTCAGCACATGCCAGAGCGATACATCATACTGTACAGAAACCAACAAAACAGCACTCCCCCTTCGAATGCAAGCCGTGCAACAAGCGCTGGGCGCGCTACAACGGTCTCTGGCTGCACAACAAGACGTCTCACGGCGCGCACAAGGCCGCGTACTGCGTGGAGTGTGACAAGCAGTACCGGGACGTGTACCGATACCGCTGGCACCTCGCTAACAGCGCCAGACACTCGCAGCACAGGAAACATAGGATCCCCTGTCCCGGTTGTGACAAGATCTTCTCGAAGAACATCTACATGAAAGACCACTATAACCTCGTTCACCTCAAGTTTTACAAGTATCGATGTGAACAATGCGATAAGAACTTCATTCGTAACGCTGACTTGGTGAAGCATACTCGCCGAGTCCACGAGGGCATACTACCGCCCAAGAACAAGATATGTTACATGTGCGGCAGGGGATTTTCTaCCAACAAGATTCTGACCAACCATTTACGAACACACACAGGAGAGAAGCCCTTTGCCTGTTCTTTATGCAACGCGCGCTTCGCACAGAGTACAGCTTTGTCAGCACACGCAAGAGCGATACATCATACTGTACAGAAACCAACGTAG
Protein Sequence
MDETEIKYEFPNYENQCSVCLSVGRKLSLLGEYIGVFKSITSDVRNHSQTPLEDIKLCWECNAFLRRASIFQQQVSKANEMLQLRQSYLYGTQSSLTTIILNDSHPHTIYVNDLNVKVQPETKICDNNSDDDEINDNCEFGDDCTKTEEVTKESTEYTRQCFRRVQIDDEELRCLLKSEREGVYFKSKKFKCDSCILAFSSQEMLEKHDKKFHCKLTKYTCDICTSRISSKRLLSEHIRGHYNKYVCTLCDFTCYDKSQTKSHQQKRHRKVFQCLKCELKFGSRWEFFKHYKEWHEKFVCDFCGISFKMRYCIKDHIRKQHSPFECKPCNKRWARYNGLWLHNKTSHGAHKAAYCVECDKQYRDVYRYRWHLANSARHSQHRKHRIPCPGCDKIFSKNIYMKDHYNLVHLKFYKYRCEQCDKVPCATGQWDKGISVGGRKISNLRYADDTTLLTQTREDMEHLLTRLETTSLSFGLTINRDKTKMMIVDRAELNHPDISMVGNCEVVQSYVYLGSTITNTGGCEDEIRRRCAITRSAVDKLKRVWCNRNITKATKVRLMRSLVFPIFLYGAETWTVRLKDRRKIDALEMWCWRRLLRIPWTAFRTNVSILEELKVKQRLSSTVQTRIIQYFGHVNFIRNADLVKHTRRVHEGILPPKNKICYMCGRGFSTNKILTNHLRTHTGEKPFACSLCNARFAQSTALSAHARAIHHTVQKPTKQHSPFECKPCNKRWARYNGLWLHNKTSHGAHKAAYCVECDKQYRDVYRYRWHLANSARHSQHRKHRIPCPGCDKIFSKNIYMKDHYNLVHLKFYKYRCEQCDKNFIRNADLVKHTRRVHEGILPPKNKICYMCGRGFSTNKILTNHLRTHTGEKPFACSLCNARFAQSTALSAHARAIHHTVQKPT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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