Basic Information

Gene Symbol
-
Assembly
GCA_029955525.1
Location
JARPMR010000026.1:15435124-15442629[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.00061 0.061 15.2 1.6 1 23 371 393 371 393 0.98
2 21 0.0002 0.02 16.7 4.6 1 23 399 421 399 421 0.98
3 21 8.9e-07 8.9e-05 24.2 0.7 1 23 427 449 427 449 0.99
4 21 0.00025 0.025 16.5 0.4 1 23 455 477 455 477 0.98
5 21 0.0015 0.15 14.0 2.3 1 23 483 505 483 505 0.98
6 21 0.00053 0.053 15.4 3.3 1 23 511 533 511 533 0.98
7 21 0.00017 0.017 17.0 6.2 1 23 539 561 539 561 0.99
8 21 0.00016 0.016 17.0 7.8 1 23 567 589 567 589 0.98
9 21 0.0031 0.31 13.0 4.8 1 23 595 617 595 617 0.98
10 21 0.0022 0.22 13.5 4.4 1 23 623 645 623 645 0.95
11 21 0.00048 0.049 15.5 0.5 1 23 651 673 651 673 0.99
12 21 0.062 6.3 8.9 4.0 1 21 679 699 679 702 0.95
13 21 0.013 1.3 11.0 2.0 1 23 708 730 708 730 0.97
14 21 4.2e-05 0.0042 18.9 1.0 1 23 736 758 736 758 0.99
15 21 0.00076 0.076 14.9 2.3 1 23 764 786 764 786 0.94
16 21 0.0015 0.15 14.0 3.3 1 23 792 814 792 814 0.99
17 21 5.5e-05 0.0055 18.5 0.3 1 23 821 843 821 843 0.98
18 21 2.6e-05 0.0026 19.5 2.0 1 23 849 871 849 871 0.98
19 21 0.00011 0.011 17.5 4.0 1 23 877 899 877 899 0.99
20 21 9.1e-05 0.0091 17.8 0.9 1 23 905 927 905 927 0.98
21 21 3.4e-06 0.00034 22.3 1.7 1 23 932 954 932 954 0.99

Sequence Information

Coding Sequence
ATGCAGTGTTTTGTGCCTGACTGCGGTAATACAGCGAGAAAGGATTCCGAATCCCTTGGAGTAACTTTTCACAAGTTTCCCGCCTCACCCCCAGAGCGCAATGCCTGGCTTCAAGCTCTCGGTGTGACCGGATctcgcgggcggcgcggcgctgtggtctgctcgcagcactTCTTAGCTGAGGACTTCTCTACCACGAGGAGTGGATCAAAGAAAATGCGACTCGGAGCTGTTCCTTTTGTAATACACGACACACAACTGTCTGATATTAATCATAAGGCAATGGAAACAGACAAAAATACAGAAGTTAACATTGAAACCGGCGATGAGCATACAGGCCGtattaaaatagaaataaaaaaagtaactGTCAAAAAACAAGCAAAAGTAGCTAATATACACAGAGTAACTGACAGAGTTGAAGTACGAATAGAAAaaatggaattaaaaaaccattCAACAGTAAATATTGTCCATGGAGCTACTGATAATGTTGAAATAGAAGTAGAAAAAGTAGAAATGTCTGATGTAGTCAATGGATCAATACTTAAACTGAAATCTTCTGATCAAAAATGTTTGGAAATTTCTTATGATAAAGCCACAAGCCACAATCAGCTTTCCAAAACCAGTTTAGAAATTAATCATTGCAGTAATGAGAATAATACACCATCTACAAAACATTCAGAACAAGCGATTGTATTATGTTCACAACCAGCAGTAGAATTAAGTTCAGAACAGGCGGTTGAACGAATTTTAGAATTATGTTCAGAAAAGGCGGTTGCATTAAGTTCAGATAAGGCTGGCGAATTATGTCTAGAAAATGCGGCAGAATTACGTCCAGATAAGGTTGTTGAATTAGGTTCAGAAAAGGGGGTAGCATTAAGTTCAGATAAGGCTGTTGAATTGAGTACCAAAAAGGTTGGCGAATTCTGTTCAGAAAAAGCTGACCAATCAAGACAAGCAGACAAGGTGGTTGATTCAAACAAACGTGGCAAACCAAGGGCCATAAATAAACGTAAAGTTGACGGAAAAAAGGAATCTGCATCGCTTCAAAGGAAAAAACCTGGTGTTAAGTATCAGCGTCCCTCTAATTATAGAAAAGGGAATAAATTCATTTGTGATTATTGTCAGTTTGTATGTAAAGGAAAGGATGGTTTGATCCTTCATATGAGGAAGCATACAGTGTATAAACCATACTCATGTAAGTATTGTGAATACAAATGTACAAGGAAAGGCTCCTTAATATCACATATAAAAAAGCACACGGGAGAGAAACCTTACCAATGTGATATCTGTGGACGAAAGTTTGTGAACACTTCCGGTCTAACCATTCACAAgcgaacacacactggtgaaaaaccattTTCATGTAAGCTATGTCCTTTAAAGTTTAGATTAAATGGCGCCTTAAAAGGTCACATGAtgactcacactggtgagaaacGATACATTTGCAGCGTATGCCAGTCTAGATTCAGAACCAGTACGTGTTTGGCGGATCATGTCAGAACTCACACAGGAGAAAAACCGTATGCCTGTGACTATTGTCAGTATAAAAGTGTGAGGAAATGTAGCTTAGTGAACCACATGCGGACACATACGGGCGAAAAGCCTTACACTTGCAAGATTTGTCACTATAAGTTTGCAAGGAACTGCTCTTTATACTTACACATGCGAGTGCACAATGGTGAGAAACTCTTTTCATGTCAGCATTGTCACAGTAAGTTTACGAGAAAAAGTTATCTAAAAATACATATCCGAAGCCACACCGGTGAGAAACCTTACGCTTGTAAATTTTGCGACTACAAATGTTCGATGAGTAGTTCTCTAAGATCCCATTCGAGgactcacacaggtgaaaaaccttactTATGTCTGCACTGCGACTATAAATGCACTACCTCAGGCTCTCTAAGATCGCACATGACGGTTCATAGCAAGGAAAAGCCTTATTCGTGCAAGCTCTGTGACTATAGAGCTGCCCAACCGGGTCGCCTAAAGTCCCATATGAAGACACACACAGGGGAAAAACCCTATTCTTGCGACAGGTGTCCGTACAAATGTGCTACGAAATACGGTTTAAGGAGTCACATTAACTGTGTACACGAGTTGATCAAGGCCTTTCGCTGTGAACATTGCGAGTATAGTGCAAGTTCGAAATATGCTTTAAGTGAACACAGCACGACTCACACTGGGGAAAAACCATATTCATGCCAGGACTGTGATTACAAAGGCGCGTCCAAATCGGCTCTACAAAAACACAAGCGAACGCACACTGGTATAAAGCCGTACCAAtgtaaagtttgtatgtataaaTTTTCAAGATTCGGCAATTTGAAGAAGCACATGCCAACTCACACGGGGGAAAAACCTTACTCTTGCAACTTGTGTCAATACAAGACTGCTAGAAAAGACTGTTTAAAGGTGCACGCCAGGACTCACACGGGCAGAGAGAAGCGTTACAGCTGCGACGTGTGCAGCATGGCCTTCAATGAAAAGGGCTCTCTGAGGCGGCACGTGAACACACACACCGGCGTTAGACCGTTCAGTTGCGAACTGTGCCCTCGCAAGTGCGCCACGAAGAGCTCTTTAAACGAACACATGAGAttgcacactggtgaaaaaccttactCTTGCAAGCATTGCAATTACAGAACCACGGGCACTAGCTCTCTAACAGTACACATGAGAACGCACACTGGCGAGAAACCTTATGCGTGTAAGATTTGTCGATACAAGAGCACGACTGCGAGTGGTCTGAGGAGCCACTTGAGGACGCACACTGGTGAGAAATACACTTGCGATGTGTGTGACACTAAATACGTGGATAAAAGCAAGTTACGAAAGCACATGACAACTCATAAGTTTGAGTAA
Protein Sequence
MQCFVPDCGNTARKDSESLGVTFHKFPASPPERNAWLQALGVTGSRGRRGAVVCSQHFLAEDFSTTRSGSKKMRLGAVPFVIHDTQLSDINHKAMETDKNTEVNIETGDEHTGRIKIEIKKVTVKKQAKVANIHRVTDRVEVRIEKMELKNHSTVNIVHGATDNVEIEVEKVEMSDVVNGSILKLKSSDQKCLEISYDKATSHNQLSKTSLEINHCSNENNTPSTKHSEQAIVLCSQPAVELSSEQAVERILELCSEKAVALSSDKAGELCLENAAELRPDKVVELGSEKGVALSSDKAVELSTKKVGEFCSEKADQSRQADKVVDSNKRGKPRAINKRKVDGKKESASLQRKKPGVKYQRPSNYRKGNKFICDYCQFVCKGKDGLILHMRKHTVYKPYSCKYCEYKCTRKGSLISHIKKHTGEKPYQCDICGRKFVNTSGLTIHKRTHTGEKPFSCKLCPLKFRLNGALKGHMMTHTGEKRYICSVCQSRFRTSTCLADHVRTHTGEKPYACDYCQYKSVRKCSLVNHMRTHTGEKPYTCKICHYKFARNCSLYLHMRVHNGEKLFSCQHCHSKFTRKSYLKIHIRSHTGEKPYACKFCDYKCSMSSSLRSHSRTHTGEKPYLCLHCDYKCTTSGSLRSHMTVHSKEKPYSCKLCDYRAAQPGRLKSHMKTHTGEKPYSCDRCPYKCATKYGLRSHINCVHELIKAFRCEHCEYSASSKYALSEHSTTHTGEKPYSCQDCDYKGASKSALQKHKRTHTGIKPYQCKVCMYKFSRFGNLKKHMPTHTGEKPYSCNLCQYKTARKDCLKVHARTHTGREKRYSCDVCSMAFNEKGSLRRHVNTHTGVRPFSCELCPRKCATKSSLNEHMRLHTGEKPYSCKHCNYRTTGTSSLTVHMRTHTGEKPYACKICRYKSTTASGLRSHLRTHTGEKYTCDVCDTKYVDKSKLRKHMTTHKFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-