Basic Information

Insect: Odontomyia ornata
Gene Symbol: topi
Assembly: GCA_963969285.1
Location: OZ017739.1:12065128-12080262[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.74 3.1e+02 5.2 0.7 2 17 200 215 199 218 0.79

2 11 3.6e-05 0.015 18.8 2.4 1 23 280 302 280 302 0.97

3 11 0.41 1.7e+02 6.0 0.2 2 21 325 344 324 347 0.76

4 11 0.0025 1.1 13.0 0.2 2 23 413 434 412 434 0.95

5 11 0.84 3.6e+02 5.0 0.0 1 20 440 459 440 461 0.91

6 11 0.081 34 8.2 2.5 1 21 480 500 480 504 0.90

7 11 1.3e-06 0.00053 23.4 1.9 1 23 556 578 556 578 0.95

8 11 0.0014 0.58 13.8 1.0 1 23 584 609 584 609 0.95

9 11 0.62 2.6e+02 5.5 1.7 1 23 615 637 615 637 0.88

10 11 7.3e-07 0.00031 24.1 0.3 3 23 645 665 643 665 0.98

11 11 0.0031 1.3 12.7 1.0 3 23 673 694 671 694 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.74	3.1e+02	5.2	0.7	2	17	200	215	199	218	0.79
2	11	3.6e-05	0.015	18.8	2.4	1	23	280	302	280	302	0.97
3	11	0.41	1.7e+02	6.0	0.2	2	21	325	344	324	347	0.76
4	11	0.0025	1.1	13.0	0.2	2	23	413	434	412	434	0.95
5	11	0.84	3.6e+02	5.0	0.0	1	20	440	459	440	461	0.91
6	11	0.081	34	8.2	2.5	1	21	480	500	480	504	0.90
7	11	1.3e-06	0.00053	23.4	1.9	1	23	556	578	556	578	0.95
8	11	0.0014	0.58	13.8	1.0	1	23	584	609	584	609	0.95
9	11	0.62	2.6e+02	5.5	1.7	1	23	615	637	615	637	0.88
10	11	7.3e-07	0.00031	24.1	0.3	3	23	645	665	643	665	0.98
11	11	0.0031	1.3	12.7	1.0	3	23	673	694	671	694	0.95

Sequence Information

Coding Sequence: atgaattttaacgatgattATGTCGAATCTGAGTCATGGTTAACTGAAAGAATTTTCTCGCAATTGAAAGAATATAATCCCCACGAGCGGGAACCACAGAATGTTCAACTTCCATTAAATTCATCAAATGTTGAACCTATTGTAGCGAGTAATGACGCAAATAGTCTGACAAATAACAGCACTCCACAAGGACCATCAATGACGGGGGTATCTGCGGAAAATAAAGTGGTATTCAATAATTCTGGGCAATCTGGAACCTATCACTGCAGTGACCGGGGAGAAATGCAACAAAGTCAAATAACTCACGCTAGCCCGTACATCGCCCCCATTCCCACCGAGCTTACAAATCAGGATATCACAAGGATGGCATGGGACGTGATTTCTAACTTAAACGATAACTCAAGAGATTCAATGGTTGTTCTTGAAGCTGACCAAGCCCAAAGATATTATGAATTAATGAGAGCTTACGTCGCCGCTCCGCACAATATTCCTTTTGAGTATTTTCCAGTTTCAGATGATGTGGTCGTTGTAAATGAGCCCGATCCCGAAAATGATCAACAGTCACAACAAGCTGCAACAACGCAAATGTATGCTATACAATGTACCCACTGTGATGAAATATTTGAGGAAAATGAGTTTCTGACGCATGTATGCGACTACGATGAAAACAAGGTTCTAATCAAGGACGAAGAAGATATCAAATGCCCAATAACCGAGGAAATCGTTGAACCCCCATGTATTCGTCAACTGCGTGAAAATAATGTTCGCATAAGAAAGTTCCTCAAAGACGAATTGAAAATAGATTTAGGAGGATCTACGAAGACTCAGGATGGTCCACACGAGTGTACAATGTGCGAACGAAAATTTGTACATGCATCAGGGTTGGTTAGGCATATGGAGAAGCATGCTCTCGATCTCATACCGGTAACAACAAATGCTAATCAATCTGGAAGTGGTTTGAGAGTAGTGGTCAAGTGCCGAATTTGTGGCATTACATTTTTCACGACAAATGATGGGCTCAGGCATTTATCCGAAGCTCATGAGAAAATAATTAACGATTGTAGTAGTAATAATTTGAaggaagatgaggatgaagaagaagaaggaaatttAGAATTAGAACCTGAAAATTTTACGAAAGCTTTGAATATTTTAGCGACTTCAGAAGAGCACAACGCTGAGGAGGAACGGCGTGCCACGGTCTATTTGAAAGTGGTTATTTTGAATTCGTTACTTCAGTGTGAATTTTGTGATTATTCATTCTCTGAAGTATCTGACTTACTCTTGCATGAATCGTCACATGATCCCGTTCGTGGCTTCGAATGCTCTTCCTGTGGCATCAGTGTACCAACGTCCAAGGAAATCTTCCTTCATTGGCAAGCTGAGTGCCCTTATGCAAAGGACGAAACTAAGAAGAATATTaatctacaaaaatattttgtatgcaatGTCTGTGAAAACAAATTCAACTCTCATGAACAACTATACGATCATCGCTACTCGTCATATCATCTCTTCCCTCGTCTGAGCAAAACGCTTAACGTAATGCAAGTTAGTTGCGAGTATTGTGGAATATTCCACGATACTGCAAAATCAATTATGCGACACCATGAAGAAAAGCATATTAAGAAGGTGAAAAAGGAAAGCACGACTAAATATCGCCAATACTTATGCGATGTCTGTGGAAAGTCCTATACGCAATCCAGCCATTTATGGCAACACTTGAGATTCCATAGAGGTGTTAAACCGTTTGCTTGTAAGGAGCCAGGATGCAATCGACGCTTCACAATTCGACCAGATCTTAACGATCATATTCGCAAATGCCACACTGGGGAACGACCTTACCATTGTCTTGTGTGCGGAAAGCGGTTTTTAACAGGATCTGTCTTCTACCAACATCGATTGATTCATCGTGGTGAACGACGGTATGGCTGTGAGGAATGTGGAAAACGTTTCTACCGTGCCGATGCATTAAAGAATCATCAACGCATTCACACTGGCGAGAAACCATACGGATGTATGTATTGTAGTAAAAGTTTCAGGCAACGTGGGGATCGTGATAAGCACATACGGGCGAGGCACGCAAACCTGGATGCCAATGCTCGTTTCGCTGGCAATTCAAAAGATGGAGTTCCTCCGCCAGGAGGTGTAGTATATGTGGGCAACGTAGCATTCCCAACGAGCATGTTCAAGCCAATGATGCGTGATATTGACGAAAGCATTTACtgtgataaataa
Protein Sequence: MNFNDDYVESESWLTERIFSQLKEYNPHEREPQNVQLPLNSSNVEPIVASNDANSLTNNSTPQGPSMTGVSAENKVVFNNSGQSGTYHCSDRGEMQQSQITHASPYIAPIPTELTNQDITRMAWDVISNLNDNSRDSMVVLEADQAQRYYELMRAYVAAPHNIPFEYFPVSDDVVVVNEPDPENDQQSQQAATTQMYAIQCTHCDEIFEENEFLTHVCDYDENKVLIKDEEDIKCPITEEIVEPPCIRQLRENNVRIRKFLKDELKIDLGGSTKTQDGPHECTMCERKFVHASGLVRHMEKHALDLIPVTTNANQSGSGLRVVVKCRICGITFFTTNDGLRHLSEAHEKIINDCSSNNLKEDEDEEEEGNLELEPENFTKALNILATSEEHNAEEERRATVYLKVVILNSLLQCEFCDYSFSEVSDLLLHESSHDPVRGFECSSCGISVPTSKEIFLHWQAECPYAKDETKKNINLQKYFVCNVCENKFNSHEQLYDHRYSSYHLFPRLSKTLNVMQVSCEYCGIFHDTAKSIMRHHEEKHIKKVKKESTTKYRQYLCDVCGKSYTQSSHLWQHLRFHRGVKPFACKEPGCNRRFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYGCEECGKRFYRADALKNHQRIHTGEKPYGCMYCSKSFRQRGDRDKHIRARHANLDANARFAGNSKDGVPPPGGVVYVGNVAFPTSMFKPMMRDIDESIYCDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -