Basic Information

Gene Symbol
-
Assembly
GCA_963969285.1
Location
OZ017742.1:246896484-246898499[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0071 3 11.6 0.2 2 23 44 66 43 66 0.95
2 15 5.8e-05 0.024 18.1 0.2 3 21 117 135 115 136 0.94
3 15 4.1e-05 0.017 18.6 0.3 2 22 149 169 148 169 0.94
4 15 1.1e-05 0.0045 20.5 1.1 1 22 205 226 205 226 0.95
5 15 0.017 7.2 10.4 0.4 2 23 311 332 310 332 0.95
6 15 0.43 1.8e+02 6.0 3.3 2 23 347 368 346 368 0.96
7 15 4.8e-07 0.0002 24.7 2.0 1 23 374 396 374 396 0.99
8 15 1.2e-05 0.0053 20.2 2.4 1 23 402 425 402 425 0.97
9 15 0.0014 0.6 13.8 0.2 3 23 433 453 431 453 0.96
10 15 4.9 2.1e+03 2.6 0.6 1 9 459 467 459 467 0.90
11 15 0.02 8.2 10.2 1.8 3 23 507 527 505 527 0.95
12 15 0.84 3.6e+02 5.0 2.4 2 23 542 563 542 563 0.96
13 15 0.51 2.2e+02 5.7 3.6 1 23 569 591 569 591 0.75
14 15 6.2e-07 0.00026 24.3 2.7 1 23 597 620 597 620 0.98
15 15 0.0008 0.34 14.6 0.0 3 23 628 648 626 648 0.96

Sequence Information

Coding Sequence
ATGTCCGCATCACAACAGCCTACAGATGTGGCGAGTAAGTCAATATGTATGGAGGAAATACTCGACGAACAACGGGTGAACTGTAGTTACCATGACGGCACTACAAAGAATATGGGGGCTTCTTTGGTCACTTGCGAGTTTTGCCAGGCAGTCTTTGAAGATACACAGCTTCTTCAGGCACACATTCAACATGTTCACATAATCTCCGTTGTAAAAACAGAGCTAGAATTTCGTACTACACaaacatttccttcatttgcTATACCCTCGATAAGCGGAACAGGGCTGGATAACACAGTACTGAATATTTACACTGATCCGAAATTAACAGAGAAAAAACGAATTGCGTGCGAATTCTGTGGTATGAAATATAAAAATCAGGAGAATCTTGAAAAGCATATGCTGAAGACAGGGTGTTCTACCCTGGAGAGAATTGACTTCATACAGTGCAGTACATGTGGATTATCTTTTCCCGCGCGTAGCAATCTTACACGGCACCAGAAGCGAACAGGATGTGTTCAGGTGGAAGTTGATACGTCTGGTGAAGAGGCAAGTATAGAGCAGTACCCAGCGCTGAAGCCAGAAACGTTAGCACAGCGGTTGCCGAATCTTTTTTATTGTGATACTTGTGGTTTATCCTACAAAAGCCGCAGCAACTTAGTGAGACATCAAAAGAAGTCAGGGTGTCGACAAGCAAAGCTTAGCACAGTCAAAGACAATCTGAACGATGAAATATTAATAAGATCCTCAGGCAGTACGACAAATGTCACAAGTTTTGATATCAAATGTGAATTCAACGATTGCAGTACTTCTCCATTAGCTGAATACATCAACGAGACACCACAAATTCCATTGTCCAATAATGCAGCCAGTCAAGTCCTCCATTCACAAAGTCTTCCAAGTGTCGTTCTAAATTCAAGATTTGAGATAACATGCGACCTTTGCAATCGCTCCTTTGAAAACGTAAAAAGACTTTATAGTCATGCAGATACTCATGACAGTATTCCGTTAGTATTGCAAGGTGATCTCGAATTCTTGAAGTGTAAATTTTGTTTGAAACAATTTACAGATCATATTGAACGCAAAACACATGAAGCCACCCATACAGGTGATAAACCTTACGAATGTCCACATTGTCAACAGAAATTCGTTAGAAATCGAAATTTAATGCAACACATTCGAATACATTCTGGAGAGTTGCCTTTTAAGTGTGAAAATTGTTCCCAGAGTTTCAGAGATAGGCGATATCTCACTCGACACATCGAACGGAATCACTTGAAGGTTGAAAGGCTTGCGTGTACCCTGTGTGAAACGAAAGTTTATGATAAAGTTCAATTGGCATTACATATGAGGACACACATCGATGCACATACATTCGCATGTAAAAATTGTGGCAAAACTAAACAGAGCATGTCCAATCACGATCAAATTGAAGACAAACCTGAAGAACCTGAAACTGATGGATCGGAAGAGCAATCAGATCAGGAATCCAATGTTGCTAAAAACCCTAACTTATTTTGTGATCTATGCACTCGATACTTTAATGATAAGGAAACATTATACCATCATGCCGAATCTCATGAAACCATTCCGACCGCATTGAAAGATGATACTAGCTTTAGAACATGCAAATTTTGTTACGAAGAATTTCCAACTCATACCGAAAGAAAATCACATGAAGCGACACATAAACGGAAACGTCCCTACGAATGTCCTATATGCAAGAAACGATTTATTTGTGATCTCAGTAGAAACATTCATGTTCGCACGCATTCTGGTCCAGTGATTTTTGAATGTGAGAAATGTTCCAAGTCATTCAAGGAGAAAAGCGGACTGAAACGACACATCCGGCGGAAGCATTTGAAAATACGAAAAGTTATTTGCGATTTGTGTGATCAAAGGTTTTTCGATCGGGTAGCATTAGCGATTCATATGTTGTCTCACATTAAGGAGGGAAATTACGTTTGTAAAACATGCATAAATTGTAGCCGGAAAAATGATAATAAACAaagttaa
Protein Sequence
MSASQQPTDVASKSICMEEILDEQRVNCSYHDGTTKNMGASLVTCEFCQAVFEDTQLLQAHIQHVHIISVVKTELEFRTTQTFPSFAIPSISGTGLDNTVLNIYTDPKLTEKKRIACEFCGMKYKNQENLEKHMLKTGCSTLERIDFIQCSTCGLSFPARSNLTRHQKRTGCVQVEVDTSGEEASIEQYPALKPETLAQRLPNLFYCDTCGLSYKSRSNLVRHQKKSGCRQAKLSTVKDNLNDEILIRSSGSTTNVTSFDIKCEFNDCSTSPLAEYINETPQIPLSNNAASQVLHSQSLPSVVLNSRFEITCDLCNRSFENVKRLYSHADTHDSIPLVLQGDLEFLKCKFCLKQFTDHIERKTHEATHTGDKPYECPHCQQKFVRNRNLMQHIRIHSGELPFKCENCSQSFRDRRYLTRHIERNHLKVERLACTLCETKVYDKVQLALHMRTHIDAHTFACKNCGKTKQSMSNHDQIEDKPEEPETDGSEEQSDQESNVAKNPNLFCDLCTRYFNDKETLYHHAESHETIPTALKDDTSFRTCKFCYEEFPTHTERKSHEATHKRKRPYECPICKKRFICDLSRNIHVRTHSGPVIFECEKCSKSFKEKSGLKRHIRRKHLKIRKVICDLCDQRFFDRVALAIHMLSHIKEGNYVCKTCINCSRKNDNKQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-