Obru007036.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Odontomachus brunneus
Gene Symbol
TEAD1
Assembly
GCA_010583005.1
Location
NW:814593-955639[+]

Transcription Factor Domain

TF Family
TEA
Domain
TEA domain
PFAM
PF01285
TF Group
Helix-turn-helix
Description
The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and AbaA. The TEA domain is located toward the N terminus of eukaryotic transcription factors of the TEA/ATTS family. It shows a three-helix bundle with a homeodomain fold [3, 1]. Two α-helices are nearly anti-parallel and pack on either side of the third one, which is the DNA-recognition helix of the TEA domain. Phosphorylation of one or both of the two conserved serines found on the DNA-binding surface could interfere with DNA-binding activity, by introducing electrostatic repulsion and/or steric hindrance, and help regulate the transcription factor activity of the proteins [2, 1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.1e-31 2.4e-27 94.4 0.1 2 66 156 222 155 224 0.96

Sequence Information

Coding Sequence
ATGACTCATCCTTCGCGACGACGCAGCGTCAAGTGCATTTCCTGGCCTGGCCTGGCGCATCCCAACCTAaactctctcttcccctccctctcgcGCGCCACCAAGCGTCTGTCACTCTTCGCCGTGCTCGTGTTCCTTCTCCTCGCTCCAACCTCGTCGGcctcccctctcctctcctctcttcttcccgGTCTCGCTCATTTTCTCCGCTCTCTTCTCCGGCGGCGACCGACGAGGAGCAGCGCGCGTCTCAGTGGTGCTCATGACGGAGAGAAACATCGTAAAGTCGGGATACACGCTCGATGTCGCGGCAGTGCGGTGGCTGCAGCCGACACCATTTCCGCGCCGTGGACCCCCGCGAGTTCCGGGCCGCCGCCCGACGCCAACGGCTCCGGCTCGGATACGAAGAACCTCGACGTTGGCGAAATTAGCGATGACGAGAAGGACCTGTCGGCAGCGGACGCGGAGGGTGTGTGGTCGCCGGATATCGAACAGAGCTTCCAGGAAGCTCTTACCATATATCCGCCATGTGGTCGTCGCAAAATCATTCTTTCCGACGAAGGGAAGATGTACGGTCGCAACGAGCTAATCGCCCGCTATATCAAATTGAGGACCGGTAAGACGAGAACGCGAAAGCAGGTGTCCTCGCACATACAGGTCCTCGCGAGAAGAAAACTCCGGGAAATACAGGCGAAACTCAAAGTGGATCATGCAACCAAGGAGAAGACGCTCCAGACAATGTCGAACATGTCGAGCGCCCAGATAGTATCAGCTGGAAGTTCGATACACAACAAGATGACCCCCGCCCTCGTGGGGCACCTTGCCCTTCACGCTTCCACCCCTGTCTCCTATCCCGGAGCGCAATTCTGGCAGCCAGGACTGCAGCCGGGAACGTCTCAGGATGTCAAGCCGTTCCCCCAGCCCGCCTACACCGGGAAACCGGCAACGGCGGTCTCGAGTGGCGACATGGTCCagccggcgccgccgccgccgtgggAAGGACGCGCCATCGCCTCCCACAAGCTCAGGCTCGTCGAGTTCACGGCCTACATGGAGCAGCACAGAAATCAGGAGATGTACCACAGGCACTTATTCGTCCAGATAGGGGGTCCTGCAGTTTACGGAGATCCGTTGGAAGCAGTCGACATTAGGCAGATATACGACAAATTCCCGGAGAAGAAGGGCGGTCTGAAAGAACTGTACGATAAGGGACCTCAGGCGGCTTTCTTCCTCGTTAAGTTTTGGGCTGATCTCAATACCAACATCCAAGACGAAGCTGCTGCATTCTACGGTGTCACGAGCCAGTACGAGAGCAACGAACACATAAAGATGATAACGTGTTCGACGAAAGTGTGCTCCTTCGGCAAGCAGGTGGTGGAGAAGGTGGAAACGGAATACGCCAGGTTTGAGAACGGCAGGTTCGTCTACCGCATCAGAGAGTCGCCCATGTGCGAATATATGATCAACTTTATTCACAAACTGAAGCACCTGCCGGAAAAGTACATGATGAACAGCGTTCTCGAGAATTTCACCATCCTCCAGGTTGTCACGGATAAGGATACGCACGAGACATTACTGTGCACGGCGTATGTGTTCGAAGTATCGACGTCCGAACACGGTGCTCAGCATCACATATACAGATTGGTCAAAGACTAG
Protein Sequence
MTHPSRRRSVKCISWPGLAHPNLNSLFPSLSRATKRLSLFAVLVFLLLAPTSSASPLLSSLLPGLAHFLRSLLRRRPTRSSARLSGAHDGEKHRKVGIHARCRGSAVAAADTISAPWTPASSGPPPDANGSGSDTKNLDVGEISDDEKDLSAADAEGVWSPDIEQSFQEALTIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKLKVDHATKEKTLQTMSNMSSAQIVSAGSSIHNKMTPALVGHLALHASTPVSYPGAQFWQPGLQPGTSQDVKPFPQPAYTGKPATAVSSGDMVQPAPPPPWEGRAIASHKLRLVEFTAYMEQHRNQEMYHRHLFVQIGGPAVYGDPLEAVDIRQIYDKFPEKKGGLKELYDKGPQAAFFLVKFWADLNTNIQDEAAAFYGVTSQYESNEHIKMITCSTKVCSFGKQVVEKVETEYARFENGRFVYRIRESPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTDKDTHETLLCTAYVFEVSTSEHGAQHHIYRLVKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01355268; iTF_00452539; iTF_00016641; iTF_01476877; iTF_00229985; iTF_00233186; iTF_00221219; iTF_00231942; iTF_00219756; iTF_00221870; iTF_00214352; iTF_00232565; iTF_00226553; iTF_00216349; iTF_00224510; iTF_00294433; iTF_00395233; iTF_00733921; iTF_00963809; iTF_01198626; iTF_00015332; iTF_00417517; iTF_00181264; iTF_00295204; iTF_00397252; iTF_01199365; iTF_00297510; iTF_00252775; iTF_00292231; iTF_00200712; iTF_00292904; iTF_00295972; iTF_00773768; iTF_00841032; iTF_01050344; iTF_00004630; iTF_01120168; iTF_01234984; iTF_01070985; iTF_00422346; iTF_01099147; iTF_01228331; iTF_01395083; iTF_01421515; iTF_00183245; iTF_00762509; iTF_01036973; iTF_00754606; iTF_01344879; iTF_01077424; iTF_00079889; iTF_00898705; iTF_00047922; iTF_00391250; iTF_00760946; iTF_00265651; iTF_01057605; iTF_01101286; iTF_01056776; iTF_00266416; iTF_00829460; iTF_00262619; iTF_00263419; iTF_00763187; iTF_01473139; iTF_01474643; iTF_00633588; iTF_01130773; iTF_01477525; iTF_01035382; iTF_00143831; iTF_00756599; iTF_00398040; iTF_01487000; iTF_00141785; iTF_00059418; iTF_00905385; iTF_00309466; iTF_00385274; iTF_00298267; iTF_01110075; iTF_01112553; iTF_01537915; iTF_00142428; iTF_00252028; iTF_00264956; iTF_00770332; iTF_01520188; iTF_00229309; iTF_00730013; iTF_01048189; iTF_01364606; iTF_00015999; iTF_00014679; iTF_00255039; iTF_01270463; iTF_00296736; iTF_01232960; iTF_01003489; iTF_01001221; iTF_00996304; iTF_00451899; iTF_01000509; iTF_01005044; iTF_01207317; iTF_01508822; iTF_01523318; iTF_01122391; iTF_00159067;
90% Identity
iTF_01234984;
80% Identity
-