Basic Information

Gene Symbol
-
Assembly
GCA_949825065.1
Location
OX463868.1:5164693-5170903[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 2.8e-05 0.0021 19.4 0.8 1 23 233 255 233 255 0.98
2 19 0.00051 0.04 15.4 1.9 1 23 261 283 261 283 0.98
3 19 0.01 0.79 11.3 8.1 1 23 289 311 289 311 0.98
4 19 0.00015 0.011 17.1 9.1 1 23 317 339 317 339 0.99
5 19 1.2e-07 9.4e-06 26.8 0.7 1 23 395 417 395 417 0.98
6 19 2.1e-05 0.0016 19.7 0.6 1 23 423 445 423 445 0.97
7 19 9.6e-05 0.0075 17.7 2.4 1 23 451 473 451 473 0.98
8 19 0.033 2.6 9.7 2.0 1 23 479 501 479 501 0.98
9 19 0.051 4 9.1 6.6 1 23 506 529 506 529 0.97
10 19 8e-05 0.0062 17.9 1.9 1 23 663 685 663 685 0.95
11 19 2.7e-06 0.00021 22.5 1.0 1 23 691 713 691 713 0.98
12 19 6.6e-07 5.2e-05 24.5 0.4 1 23 719 741 719 741 0.99
13 19 0.00027 0.021 16.3 0.1 1 23 747 769 747 769 0.97
14 19 2.8e-05 0.0022 19.4 3.8 1 23 775 797 775 797 0.98
15 19 1.3e-06 0.0001 23.5 0.2 1 23 868 890 868 890 0.98
16 19 3.8e-05 0.003 18.9 4.6 1 23 896 918 896 918 0.98
17 19 6.8e-05 0.0053 18.1 0.1 1 23 924 946 924 946 0.97
18 19 7.5e-08 5.8e-06 27.4 0.6 1 23 952 974 952 974 0.98
19 19 0.00027 0.021 16.2 1.8 1 23 980 1002 980 1002 0.99

Sequence Information

Coding Sequence
ATGGTTGACTACGCTAAGGATGAGGACTCTGTATCATTTGCGATGGCCCTCTCTTCAGAGCGTACCCTGTACAACTTTGCGTCGGACCCCACTCCGATGGTGCCCCTGCACTGTACCGTCCCGTATCACATCAAAAGCGAGTGCGAGGCTGACGGAGACAGGTGGAAAGAGGAGAGACAGGATCTAGGGCTCATTGACATGGATAAAGTCAAAATTGATAAGGtcGATTGTTGCGACCTCTCGAACGAAGGATTCGTCAAGCCGTCACAAACAACGGGGAGATTCGACGAATGCAAGGTCGAAGATCTGGAAGAAAACACTTTGAAAGACACGTCCGTCAGTCTACATGATACACGTTCAACTTCTACGAATAGTATTCGACATACCGTCAATCAGTCcactcaaaataataataataatagtgagAACGTTAATTCGTCTTCCGTCTTCAACACGGCACTTGAAGCGTTGAATTCGGAAATGAGAAATGATAGGACAGACAATGTCGTGCCGATATTTGATACGATAGTAAATTCTAACGAAGCGATTACCGAGAAAATTAGTGATTcgtattcattaaataaagaaatatctgATGTAAAGCATATTGGTTCGTATAATGATCGTACGAAAAAGCTGGATGACGAAATGGGTACTGGGGAAGGTAACGAAGAGAATAAAGCTCCCGAAAGACGATACATTTGTGATGTATGTAGCAAAGAATTCCGATTGGCGAGTAAGCTAAAATACCACATGATGACGCACACGGGCGAGAAGAATTACGCTTGTCACATATGCGGTCACCTTTTTCCGCAGGTCAGTCGACTTAAAACACATTTACGTGTCCATACAGGGTTTAAACCGTACCattgtgacgtttgtcaaaagagATTCTTCCATTCGCATCAACTGCAAGGCCACAAAAGGATTCATAGCGGAGAGAAGCCGTACGTGTGTCGGCTGTGTCACAAGTCATTTACGCAATCGCATCACGTTAAGAAACATATCAAAACTCATTTGGTTAAAGAACCGTATTTGTACGAGGAGAACGGTCAGTTATTTACGAGCGCTAGTCCGCTAGAGGGACAGACGATAGTACCGTATTTCAAACCTTATTTACGGATACAGacgaaagaaaagaaaagaaacaagGGCGGGGAAATTAAAAAAGGGGATAAACCGTTTGTTTGCGATGTTTGTTCGAAGAGTTTTACCCAAAAGGGTAACTTGCAAAGGCACCAGTTGGTCCATTCGGGAAAGAAGCCTTTCTCGTGCGAGATTTGTTTGAAGACGTTCACGCAAGTCGGCAATTTGCAAAGGCACAAGTTGATACATTCCGGCGAGAAGAAATACTCGTGTTCTCAATGTGACAAGTCCTTCATACAGTTGATTCATCTTGAACTTCATAAAAAGAGTCATAACGTTGAGAAAGAGTTTTCTTGCGACGTATGTATGAGGTCGTACAAGACTGTGCAGTCACTAAAGACACACAAGCAATCGCACGTACATAAAAGTTATAGATGTAAGATTTGTGATTGTAAATTTACGTGTAAAGACGATTTGAAGGATCACAAAACTACTGTACATGCGAAATACGTACGTTcgaaaaagaggaaaaaagaaaagaagaagataaaagaaGAATTCGAAGAAGAAAGAGAGGATTATGATGAATCTAAAGACGGTTTTGAAGAGATAGATATGGATTTGTTACAAGATGATTTCACGGATATTAAAGAAAATCTTTCACACGTTGATTTAGAGGATATAAAGGTTGAACAGAAAGaagaaagtattgttgaagAAATTAAACAAGAAGCGGAAGGAGAATTCAAAGAGGAATTTGACTTTGATCCGGATCCTGTCACGTCAGCGGATTTGGACGAAGATTTTGAACCAGAAGTGCCTAAGAAAACTAAGAAACGTACGCACAAAAAGACGATAGATAGAACAGGAAAGAAGAAGAGTCAACCTACGAAAGGTTGTTTCTTATGTACGATATGTCGTAAAACGTACCCTTACAAATATACGTTGAAGATGCATATGAAAATACATACGGGAGAGAGATCGTTCGTCTGTGATACGTGCGGGAAGTCGTTCATTTACGCTCACAATTTAGAAGATCACAAAAGGATTCACAGCGGTATAAAACCCTACGAGTGTCAAGAGTGCGGTCGCCGGTTCACGCAAGTCGGTCAACTTCAAAAGCACGTTCGGGTCCACTCAGGCGAGAAGTCGTACGCTTGCGAAGTGTGCGGAAAGCTATTCGCGAATCTAAACGGACTCCAAGTGCATTTTCGCATTCACAGCGGCGAAAAGCCGTATTCGTGTCATCAGTGCCACAAGGCTTTCGCGAGAATCAGTGGACTGAAGCAACATCAGGAGACGCATAATGGTAAACTACGTAAGAGGCCCTGTTACAAAAGACGTACGATGGACAAAACAAAGGTATCAGATAGTCTGATAGAAGATGAATTACCTCCGGAATTGCGTTGGGAAGCTAACGGTTTCAAAGAAGACGGAACTAGCGTGCCTTACAGCGAacgatataaatttttattaaaaatccccACTTCAACGAAGAAGAGAGGTATCGGAAACTTTGTTTGCGAGATATGTAATAAAGGATTTTCGTTAGCGGGTAATTTAAAAACGCACATGAAAATTCATTCCGGACTTAAACCGCACGTCTGCGAGATTTGCAAAAAGTCCTTCACGTACGCGCATAGTCTAGTTCAACACAAACGCACCCACAGCGGAGAGAAACCTTTCGTTTGCGGCGTTTGTAATAAGGCGTTTTCGCAAATAGGGAATTTGCTAAATCATAGACTCTTGCACACGGGTCAGAAGCCTTATTCTTGTAACGGTTGCGGTAAGTCGTTTTCGAGAATGAGTTACCTTAAAGCTCACGTAAGGATACATACTGGAGAGCGTCCGTATAGTTGTTGGGAATGCGGTTTCCGATGCGCTCAAGTCAGTACTCTCAGCACGCATATGAAGACACATAGAAAGTCCGTGGAATAA
Protein Sequence
MVDYAKDEDSVSFAMALSSERTLYNFASDPTPMVPLHCTVPYHIKSECEADGDRWKEERQDLGLIDMDKVKIDKVDCCDLSNEGFVKPSQTTGRFDECKVEDLEENTLKDTSVSLHDTRSTSTNSIRHTVNQSTQNNNNNSENVNSSSVFNTALEALNSEMRNDRTDNVVPIFDTIVNSNEAITEKISDSYSLNKEISDVKHIGSYNDRTKKLDDEMGTGEGNEENKAPERRYICDVCSKEFRLASKLKYHMMTHTGEKNYACHICGHLFPQVSRLKTHLRVHTGFKPYHCDVCQKRFFHSHQLQGHKRIHSGEKPYVCRLCHKSFTQSHHVKKHIKTHLVKEPYLYEENGQLFTSASPLEGQTIVPYFKPYLRIQTKEKKRNKGGEIKKGDKPFVCDVCSKSFTQKGNLQRHQLVHSGKKPFSCEICLKTFTQVGNLQRHKLIHSGEKKYSCSQCDKSFIQLIHLELHKKSHNVEKEFSCDVCMRSYKTVQSLKTHKQSHVHKSYRCKICDCKFTCKDDLKDHKTTVHAKYVRSKKRKKEKKKIKEEFEEEREDYDESKDGFEEIDMDLLQDDFTDIKENLSHVDLEDIKVEQKEESIVEEIKQEAEGEFKEEFDFDPDPVTSADLDEDFEPEVPKKTKKRTHKKTIDRTGKKKSQPTKGCFLCTICRKTYPYKYTLKMHMKIHTGERSFVCDTCGKSFIYAHNLEDHKRIHSGIKPYECQECGRRFTQVGQLQKHVRVHSGEKSYACEVCGKLFANLNGLQVHFRIHSGEKPYSCHQCHKAFARISGLKQHQETHNGKLRKRPCYKRRTMDKTKVSDSLIEDELPPELRWEANGFKEDGTSVPYSERYKFLLKIPTSTKKRGIGNFVCEICNKGFSLAGNLKTHMKIHSGLKPHVCEICKKSFTYAHSLVQHKRTHSGEKPFVCGVCNKAFSQIGNLLNHRLLHTGQKPYSCNGCGKSFSRMSYLKAHVRIHTGERPYSCWECGFRCAQVSTLSTHMKTHRKSVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-