Basic Information

Gene Symbol
-
Assembly
GCA_949825065.1
Location
OX463848.1:63325-124089[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 4.2e-05 0.0033 18.8 1.3 1 23 421 443 421 443 0.97
2 24 0.0017 0.13 13.7 0.8 1 20 449 468 449 471 0.94
3 24 0.0002 0.015 16.7 0.9 1 23 477 499 477 499 0.98
4 24 2.7e-05 0.0021 19.4 3.2 1 23 505 527 505 527 0.98
5 24 2.7e-05 0.0021 19.4 5.6 1 23 533 555 533 555 0.99
6 24 6.2e-05 0.0048 18.3 5.3 1 23 561 583 561 583 0.97
7 24 3.3e-05 0.0026 19.1 7.3 1 23 650 672 650 672 0.97
8 24 2.3e-07 1.8e-05 25.9 2.7 1 23 678 700 678 700 0.98
9 24 0.00017 0.013 16.9 6.7 1 23 706 728 706 728 0.97
10 24 0.00016 0.013 16.9 4.3 1 23 734 756 734 756 0.97
11 24 1e-06 7.9e-05 23.9 3.0 1 23 762 784 762 784 0.98
12 24 1.4e-05 0.0011 20.3 7.7 1 23 790 812 790 812 0.98
13 24 7.1e-05 0.0055 18.1 3.1 1 20 818 837 818 838 0.95
14 24 2.9e-06 0.00023 22.4 4.1 1 23 914 936 914 936 0.97
15 24 2.4e-06 0.00018 22.7 4.0 1 23 942 964 942 964 0.99
16 24 2.1e-06 0.00016 22.9 3.5 3 23 972 992 970 992 0.98
17 24 3.3e-06 0.00026 22.3 5.0 1 23 998 1020 998 1020 0.98
18 24 1.5e-06 0.00012 23.3 4.6 1 23 1026 1048 1026 1048 0.98
19 24 1e-05 0.0008 20.7 3.6 1 23 1054 1076 1054 1076 0.98
20 24 3.9e-05 0.0031 18.9 7.7 1 23 1082 1104 1082 1104 0.98
21 24 7.8e-05 0.0061 17.9 6.8 1 23 1110 1133 1110 1133 0.95
22 24 0.00022 0.017 16.5 0.3 1 23 1139 1161 1139 1161 0.97
23 24 0.0096 0.75 11.4 3.2 1 23 1171 1193 1171 1193 0.98
24 24 1.5e-06 0.00011 23.4 4.5 1 23 1199 1221 1199 1221 0.98

Sequence Information

Coding Sequence
ATGAATGCTGACCAACATAATATGAATACTGGGAGTTCACAGCCCTCTGAGAACTCGACTGagtctCAAAACCAGAGGACACAAAATCAGCACCAGCTCACCCCGACAACGTCGGCAACAGATCTCCGGGTGAACTCGGCGAACTCGGCAGCGGTGAACGTGGCCCTGTCCAGCGTAGCCAAGTACTGGGTGTTTACGAATCTATTTCCGGGGCCGTTGCCTCAGGTGTCGGTGTATGGGCTGCCCACTGCGTCTTCTCGTCTAGAGAATGGAAAGCCTATTCAGGAGTTGATCCAGCAACAACCGGCCGGGCTGCTCAATGGGGAGGCCGGCCTGCTACTGCAGCACCCCCAGCACCAGGGGCCGGGGGGCACACAGGGACTCGCCAACATCTCCATTCCTGCCGGCGCATTGCACCTGGATGTGGCCGCAGCCCTTGCGCAACAAGCTGAGCCGGGGCAGTTGCAGCAGCAGCAGCAACAACAACAGCAGCAACAACAGCAGCAACAACAGCAGCAACAACAGCAGCAACAACAGCAGCAGCAACAACAGCAGCAGCAGCAACAGAGTAACAGCAGCAACCCCCAACAACACCCCTCTTCGCAGCAACACTCCTCAGCGCAGCAGCACCAGCACCCTTCCTCGCAGCAGCAGGTACCCAATCATGTTGGGCTAGTGCACAACCCGATTCAACTGGCGGTGAGTGAGGATGGGCTGGTGACAGTGGTAGAGCAGAACAGCGGCGGGGGCAAGGCCAAGGAAGATATGGGCGTCGTGGGGCAGGGGCAAAGCCAGGGCCAGCAGCAGCAGGAGGTGCAGGCGCTCACGGTGCAGCAGCTGCAGCAGATTGTGGGCCAGCAGGTGATTGACGGTGTGGTGCGGATAGAACAAGCGGGGGAATCGGCCAACATCCTTGTCACCCACAACCCTGATGGGACCACCTCCATAGAGCAGCAGGGCAAGGAAGATAAGGGGAAACTGGACCTTAAGAGTATACAGGCAGGACAACTGATGGATGTCAGAACGGCAGATGGATCCATTGTGAAGATTGCAACGGGAGCTATCGGCTCTGCAGAACATGAACTGCAGAACATGTACAAAGTTAATGTAGAAGACTTCTCACAACTGTTGGCCTATCATGAAGTCTTTGGGAAACTAAACACGGAAACTAAGgtCCTCTCCGATACGGAGGCAGAGGCGGGTGCTAGTAACGTGTCAGAAGCAGATAGCAGTCCGCCCTCCGTGGGGCCCCCGGGGGTGCACCCCTGCGACATCTGCGGGAAGATCTTCCAGTACAGATACCAGCTCATCGTGCATCGGAGATACCACACGGAGAGGAAGCCGTTCACGTGCCAGGTTTGCGGGCAGGCCTTTGGAAATGAGGCAGACCTAACGCGCCACGGCAAGTGCCACCTCGGCGGCTCCATGTTCACCTGCTCCGTCTGCTTCCACGTATTCGCTAATGCGGCCAGTCTCGAGAGGCACGCCAAGCGTCATGCTCAAGACAAGCCCTACATGTGCACCACTTGCCAGAAGAGTTTCGCCAGGAAGGAACATCTAGACACGCACGTCCGGAGTCACACTGGGGAAACTCCCTATAGATGTCAATACTGTTCCAAAACCTTCACCCGTAAAGAGCACATGGTGAACCACGTGCGCAAACACACGGGCGACACGCCTCATCGCTGTGATATTTGTAAAAAGTCCTTCACCAGGAAAGAGCACTTCATGAATCACGTTATGTGGCACACCGAAATGAAACCTTTCCCCGTGAGCTTGACCATGGCGCACTCCGCGGACATAAAGAACATATCCCTGCCCCTGAATATCGCCATGGAGCACCCTCCCGAGCTGAAGCCGCTGCCCTTAACCTTGACACTGGTGGACTCTGCGGATATCGCGTCCGAATACCTACTCATTCCGAGAGTCGTGAAAAGCGAGACCCCGCACCACTGCCAGGTGTGTGGCAAGAAGTACACGCGCAAGGAGCACCTCGTCAACCACATGAGGTCGCACAACAACGACACGCCCTTCCGATGTGAGATCTGCGGCAAGTCCTTTACCAGAAAAGAACACTTCACCAATCACATCATGTGGCACACTGGTGAGACTCCGCACCGGTGTGACTTCTGCTCTAAGACATTCACGCGCAAGGAGCACCTCTTGAACCATGTGCGACAGCACACGGGCGAGTCCCCGCATCGCTGCGCATACTGTGCCAAGTCCTTCACGCGGCGAGAGCACCTTGTCAACCATGTGCGCCAGCACACGGGAGAGACGCCCTTCCGTTGCACGTACTGCCCCAAAGCCTTCACCAGGAAGGATCACCTCGTGAATCATGTTCGTCAGCACACGGGCGAATCCCCGCACAAGTGCACTTACTGCTCCAAATCATTCACGCGGAAGGAGCACCTGACCAACCACGTGCGCCAGCACACAGGCGAGTCACCGCACCGCTGCGGCTACTGCAGCAAGTCCTTCACGCGCAAGGAGCACCTCACCAACCATGTCAGTCCAGGTCCAGCTCCAGCTCTCAGCGTGTTAACTCTCAACTTTGCTTATGTCGAGAGCGCAGGTAAATTCTCTCTGTCATGTCATGGAACATTAGTTAAGTCTGTAGCTTCCAAGATCCGAGAGCTTACTGAAGATGAAGAGACCTGCCCGGCCTATCAGAATGTTTTGGCTTCTGAAGCAGTTTCTAGATTAGAGTTTACAAAGAGGCACACGGGTGAGACCCCCTTTGCCTGCACCTTCTGCCCCAAGTCCTTCAGCAGGAAGGAGCACCTCACCTACCACATCAGGAAACACACCGGCGAGACCCCGTACAGCTGCACATACTGCACCAAGTCTTTTGGGAGAAAAGAGCACCTCAATATTCACATCAGGAAACACACGGGCGAGACCCCATTTGGCTGCACTTACTGCCCTAAGACCTTCAGCAGAAAAGAGCATCTGACCAATCACGTCAGGAAACATACCGGTGAGACTCCGTTCAGCTGCACCTATTGCACCAAGTCCTTTGGGAGAAAGGAGCATCTCACCAATCACATCAGGAAACACACGGGTGAGACCCCATTCAGCTGCACGTACTGCGCCAAGTCTTTTAGCAGGAAGGAGCACCTCAACAATCACATCAGGAAACACACGGGAGAGTCTCCGTACGCCTGCAGCTTCTGTACCAAGGCCTTCACCAGGAAGGAGCACCTCACCAACCACACCAGGGTCCACACAGGAGAGTCCCCGCATCGCTGCGAATTCTGCCAGAAGACCTTCACGAGGAAGGAGCACCTTACTAACCACCTGCGCCAGCATACGGGAGACACACCACATTGCTGCAATGTCTGTAACAAGCCGTTCACGCGCAAGGAGCACCTCATCAATCACATGAGCCGCTCTCACACAGGTGAACGGCCATTCGCTTGCGAGGAATGTGGCAAGACCTTCCCGTTGAAGGGGAACCTGCTCTTCCACCAACGCTCGCACAACAAGGGCACACAGGCCTCGCGTCCCTTCCGCTGCGATCTCTGCCCCAAGGACTTTGTGTGCAAAGGGCACCTGGTGTCGCATCGGCGTGTGCACACTGGCGAGAAGCCGCACACATGCGAGCACTGCGGCAAGACCTTCGTGGACAAGGGTAACATGATGCGGCACCTGCGCAAGCACGAGGAGCTGGCCGAGGCGTCCGATCATATGGCTTCGACCGTGGTGACTGTGGTGGGCGATGAGCCTGAGGTGCTGCTGGACGCCTCTCAGCAGCCTCCGCCACCCCCGCCCCAGGCACAGCAGCCCCCACCACCCCTCATGCACATGACCAGCCAGGTACTTATTGACTTTACAATGCAGACTTAG
Protein Sequence
MNADQHNMNTGSSQPSENSTESQNQRTQNQHQLTPTTSATDLRVNSANSAAVNVALSSVAKYWVFTNLFPGPLPQVSVYGLPTASSRLENGKPIQELIQQQPAGLLNGEAGLLLQHPQHQGPGGTQGLANISIPAGALHLDVAAALAQQAEPGQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSNSSNPQQHPSSQQHSSAQQHQHPSSQQQVPNHVGLVHNPIQLAVSEDGLVTVVEQNSGGGKAKEDMGVVGQGQSQGQQQQEVQALTVQQLQQIVGQQVIDGVVRIEQAGESANILVTHNPDGTTSIEQQGKEDKGKLDLKSIQAGQLMDVRTADGSIVKIATGAIGSAEHELQNMYKVNVEDFSQLLAYHEVFGKLNTETKVLSDTEAEAGASNVSEADSSPPSVGPPGVHPCDICGKIFQYRYQLIVHRRYHTERKPFTCQVCGQAFGNEADLTRHGKCHLGGSMFTCSVCFHVFANAASLERHAKRHAQDKPYMCTTCQKSFARKEHLDTHVRSHTGETPYRCQYCSKTFTRKEHMVNHVRKHTGDTPHRCDICKKSFTRKEHFMNHVMWHTEMKPFPVSLTMAHSADIKNISLPLNIAMEHPPELKPLPLTLTLVDSADIASEYLLIPRVVKSETPHHCQVCGKKYTRKEHLVNHMRSHNNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCAYCAKSFTRREHLVNHVRQHTGETPFRCTYCPKAFTRKDHLVNHVRQHTGESPHKCTYCSKSFTRKEHLTNHVRQHTGESPHRCGYCSKSFTRKEHLTNHVSPGPAPALSVLTLNFAYVESAGKFSLSCHGTLVKSVASKIRELTEDEETCPAYQNVLASEAVSRLEFTKRHTGETPFACTFCPKSFSRKEHLTYHIRKHTGETPYSCTYCTKSFGRKEHLNIHIRKHTGETPFGCTYCPKTFSRKEHLTNHVRKHTGETPFSCTYCTKSFGRKEHLTNHIRKHTGETPFSCTYCAKSFSRKEHLNNHIRKHTGESPYACSFCTKAFTRKEHLTNHTRVHTGESPHRCEFCQKTFTRKEHLTNHLRQHTGDTPHCCNVCNKPFTRKEHLINHMSRSHTGERPFACEECGKTFPLKGNLLFHQRSHNKGTQASRPFRCDLCPKDFVCKGHLVSHRRVHTGEKPHTCEHCGKTFVDKGNMMRHLRKHEELAEASDHMASTVVTVVGDEPEVLLDASQQPPPPPPQAQQPPPPLMHMTSQVLIDFTMQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-