Basic Information

Insect: Nowickia ferox
Gene Symbol: zfh2
Assembly: GCA_936446695.1
Location: CAKZFO010000158.1:996723-1021229[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0023 0.22 13.0 0.6 2 23 200 222 199 222 0.97

2 6 0.085 8.4 8.1 1.6 3 22 289 308 288 311 0.90

3 6 0.00092 0.09 14.3 1.7 1 23 362 384 362 384 0.97

4 6 0.011 1.1 10.8 2.3 2 23 391 413 390 413 0.94

5 6 0.0004 0.039 15.4 1.7 1 23 1122 1144 1122 1144 0.97

6 6 0.004 0.39 12.3 5.6 1 23 1236 1258 1236 1258 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0023	0.22	13.0	0.6	2	23	200	222	199	222	0.97
2	6	0.085	8.4	8.1	1.6	3	22	289	308	288	311	0.90
3	6	0.00092	0.09	14.3	1.7	1	23	362	384	362	384	0.97
4	6	0.011	1.1	10.8	2.3	2	23	391	413	390	413	0.94
5	6	0.0004	0.039	15.4	1.7	1	23	1122	1144	1122	1144	0.97
6	6	0.004	0.39	12.3	5.6	1	23	1236	1258	1236	1258	0.95

Sequence Information

Coding Sequence: ATGTTCTTTGACCAGAATGAAGAAGgtgaaaataatacaaacatGCAAAGCTTAGGAAATCTTACATCGGCAATTCAATTAACTCATCAGCAGCAAGATTGCAGTAAAATAAAACAGACCTTTGTAGAAAAAAATGCAGATGTTACTTCCAGCAATGTACCAGCAATAATTTTCAAGTGTAAAAACTGTGACTTTTTTGGACAATTGAAGCAAGAAGTAGAAGCACACAATGCGATATTACATCCCAACTGTGATAGCAGTGATGTTATAAGTATACCCACCAATCCAGTGGCAATACAAGCCTTTCAAGCCGCTATGGCAGCAGCAACATTGGCAGCTGTAAGCCAAGCAACGAAGACTTCTCTAACTCCCTCGCCGTCAGCATCACCAAACTTAACACAGACCAATATGAATACAGCCAAGCAGGACAATGAAGATTATCTCTGTCCAGTGGCCGTTAAACGCGAATGTCTTGACTTAGACGAGTCAGAACTTTTGTCAGAGGATCCAACAGCTGCATTAAATGAGCCAAGTGCATCCACCGAAATAATTGAGCGACAAACGACTATCACTCAGGTGAAACAAAGTAATGGTGTGCAGTGTCCATTGTGCCAAAATTACTTCACGAAGAAAACAACACTAGAAACACACTTAATGACTGTGCATAGCGTAAATAAAGATGGTTTAGCTCGTCTTTTGTTATTGGTTGATACCAGCATATGGCAAAGTGAAGAAACTTGTCTTGACAGCCGTCCCACACAACACACAGTCGGCGAAGCATCAACATCTTCCTCAGTATCAGCGATCAGTGATACAACAATAACGAGTACTAAACCTCCACTTGCTGGCTATGAGCTATCGTTATGTCAACAGTGTGGTTCGAGCTTCAAACACGAGCAGCAGTTATTACAACACGCTCAAAAAATGCAGCATTACACGATGCAAAAAGGAGAATACATCTGCTTAGCATTTAACTCTGTACGAAATCCCTGTAAAATGCAGTTTCCATCCCTTACGGCCATGTTCAATCACTATAATGACACACATATGCGATTGGTTATATCTGAACGCCACGTCTACAAATATCGTTGCAAGCAGTGTTCTTTGGCATTTAAAACTCAAGAGAAGTTGGCAACTCACACCCTTTATCATACGATGCGTGACGCTACCAAATGCGCCATGTGTCAACGCAACTTCCGCAGCACTCAAGCCTTACACAAGCATATGGAGCAGATTCATGGCCAAACCACAAGCAGTGACAGTAATACAGAATGTGTGAGTCCAAGAGTAGTTTCACCATTGGACTGCGAAACAAGCAAACCAATGAgcggcatatgtcgaacacccAACACTATTGAAAAACTAGAAAATGAATCCAGTAGATCAGTTACACCCGGACCGGAAGCATGTCCGCCAACACAGTCACCTGGTTCAATTCAAAATGAACCTCAAAACTCACCGTCTCCATCAACATCAACACAACAACAGCCGCAGCAACAGATGTCTGCCATCACTGCTTTAATTAACCAACACCAGCAAAATGCTGCTCCTTCTGAACTGGTACATCATTTACAAATGCAACATCAACAATTCCAAAATCTACCGGCCCTACATAATCTTCAGCACATGCAACAACAATTTCCCCAATTCGCTGCTGCCATTGCTGCTTCTGGCATGCCAATCAATCCCGTCGAAATGTTGAATCTCATGCAATTTCACCACCTCATCTCCTTAAATTTTATGAACTTAGCTCCTCCGTTAATATTTGGTGGAAATGCTGCTGCAGCAGCAGCCGCTGCATCATCCGTTACCGGCTCAAATAGTACAACTCCAGCAAATGTACCAAGCAGTACTGTATCGAAACCAGCAGGTCATATTTCTGCAACAACAGATCCAACAGCTTCATTGTCAAACTTGTGCACAAACACGACACCAACGTCATCTATATCGGCCCTACCAAATGTTGATGTAAGTACACAAAtactgcaacaacaacagcagcaaattTCTCCCGTAGCATCGAATTCTCAACTGCTTAATAATCAAAAACGTGCTCGTACCCGTATTACAGACGATCAGCTTAAAATTTTGCGGGCCCATTTCGATATTAATAATTCGCCCAGTGAAGAGAGCATACTAGAAATGTCGCAGAAAGCGAATTTGCCAATGAAGGTTGTTAAACATTGGTTCCGCAATACCTTGTTTAAGGAACGTCAACGCAACAAAGACTCTCCCTATAACTTTAATAATCCACCTTCAACTACTCTAAATTTGGAAGAATACGAACGCACCGGTCAAGCGAAAGTAATGCCTCTTACAGAACAAGTGCAACATCATCAACTGCAAATACCATCGCGTCCATCGTCTACCCATTCTATCAGTAACATTAGCGAGTATTCTaatcaacagcaacagcagatGGAGAGTAAACAAAGAGAAGAATCTGATACATTACGATCACAGGCTTCAAGTGCTGCAAGCTCAACATTCCCTTTAGATGTGCAAATAAAAACCGAACCAGGTGAAGATTTAACAACCATGCCTACGTCTGTTTCAGTAGAAGGTTCTACTACAATACCTCTGACAAAGTTTCtaaaacagcagcagcagcagcaaaagGTACGCTTTCCTAGTTTGGACCAACAGGAGCACGACCTAATGATGATGTCGGAACAACATTTGTCATCAGTTGTAGCTtctcaacaacagcaacagcatgcTACACCTTCATTTTATAACAGCTATGAAACCAAATCGGAAAGTGAGAGTTCTGATATGCATTCACGTCCGCACACGCCGAACAGTAATACCACATCGAATTTGTATGCGAGCATGAACGATTTGTTAAGCCAACAGTTGGAAAATATTCCACTTAATCAAATGGGCCCcccgaaaaaatttcaaattaacccAAATTCCAATCCATGCAGCAGCAACATTAGTACTACACCTACCGATCGCAATGTGCAAGTTGGTGTGAGTGGTACCAGCAGTAGCAGCAGTATTATTGGTAGTACTGGCTCAAGTGGCATTACAGTTAGCAGTAAGTTGTTCGAAAAACACTCACCGTCAGCACAGTATGACAACAATTCAAATTCATCAAATTCCTCCACCACTTCCAGTGGCAAAAGGGCAAACAGAACACGTTTTACCGATTACCAAATTAAGGTCTTGCAAGAGTTTTTCGAGAACAATTCTTATCCTAAGGACAGTGACTTGGAATACCTAAGTAAACTATTATTGCTATCCCCCCGAGTTATCGTTGTATGGTTTCAgAATGCTCGTCAAAAGCAGAGGAAAATATACGAAAATCAACCAAACAACTCGCTCTATGAAACGGAggagaaaaaacaaaacattaattatgCTTGCAAAAAATGTAGTTTGGTTTTTCAGCGTTATTATGAGCTTATACGGCATCAAAAGAATCACTGCTTCAAAGAAGAGAATAATAAGAAATCTGCAAAGGCACAAATAGCGGCAGCCCAGATTGCACAGAACTTAAGCTCAGAAGATTCAAATTCATCAATAGATATTAATAGTGCAGCCGCTGCCGCTCTTTTGGCACACCATCATCCAGTTGTTGGAGTAGCTGCCGGATTGGGCAAAAATACTCCATCAGCGAGAGAGTTTAGTCCAGTACCAAGTAATGCCACAACACCTCCCAGAGATCAGGAAAACAGCAGTAGTACTGAACATCAGAAATTTCTTTGTGACAAATGTAAATTGACCTTTACACATTTCGATCATTTGCGTGAACACCAACTGATGCATTTGGTCAATCCCAATTTACATATGCCAAGTGAAGCACATACAACAGCCAGTGCCGCAGCAGCTGTTGCTGCCTATGGTCCTTTTGGGAGTATATTGCAAAGCCTTCAGCAGGCCGCGCACTTGCAGCAAGCGGCAGCAGCAAATTCAGCAACCCAGCAACCGGCATCCAAGAAGCGTAAATACTCAGAGACATCATCGAACGCTGACGATCTGTCTTCTATAGGCGGTTTCTCACTTACAGGTGCCGACTATGATAGTCATGccaaaaagtataattttttataccaataTTTCCTACAAAATGAGGCAAACTCTGACATACGGCAACAGTTTCATAATCAGGACAGTGCTGAATTAAATATGGAATTTCTGGCCAACTACTATCAACAGACAGAGGTAAAAAAACGTACGAACTATGAGTTTCTATTTCAATATTACGTGAGAAATGAACAGCAAGCAAATGCCAACTTTGAACTACCCGATAGCAAACCCAATAtagaatttttattgcaatattatCAACTTTATGAATCGAAAAAGTTTTTTCAGTTAGAGGCCTCGCCCCAACGAACACATGATGGACCGTCAATGCAGAGTTGTATCGACACTTCCCAACACAATATTAACGTCagtagcagcagcaacaacagcagccgTCCTGCTTCGAATGGCAGCGACCGCAGCAGCAGTCCTAGCGGCAGTGGTATTAATGAGGAGAGTAATGGGGGTGGGGTGGTTGataatattgaaaatgaaaaacactCTCCTCTAATGGCTACATACAATAACGAACATAAAACACGCTCTAATGGCCAGCActgcagtaacaacaacaacaacaatgatttattaataaatgttgAACACAATATTTGCCAAACCGATACCAGAAATGAACGATTGAATATCGGAAACGCTAAAAAATTGGAAGAACAAATGGATCAGCTGGATGGCTTACAAGAAGTGAATAATCAAGCTAATTCAAATCATGGGCCGGAATCATCACCAACACGCCTAATGTCAGCTATGACGCCAGGCTTGGGTAGCTATTACCAAAATTTAGAAGACTTTCTTGATGCCACCATGATAGAAAATCacagtcaaacacttacgtttCCCACAGAAACAAATAGTTCAGCCAATGAAGCTGCAAAAATATTAGAAGCAACTCTAAACTCAAAAAGTCAAACGGAGCAAGCTGCAATTCCTGAAAACGCCAacccaaaacaaacaaataaacgcTTGCGCACCACAATTTTACCggaacaattaaattttttatatgaatgctATCAAAATGAATCAAATCCAAGTCGTAAAATGTTGGAGGAAATAGCAAAGAAAGTTAATCTCAAAAAACGTGTTGTTCAAGTTTGGTTTCAAAATACCAGAGCCAAAGACAAAAAGTCACGTAATCAAAAGAGACAACATTTCTCAAATATATCGGATGATAATAGTAATAGCAGCAGTGTGCTCAACAATAATCTTAAGACCACTATTTCGTCACGTACAAATTTGGCAACATCAGCTGTCAGTGAAGCGTCTAATGATATAATCAGAGATTGCAATTTATGCCAAGTAACGCAAGTAAATATACAACAACATGCCTTCACCGTTGAACATATACATAAAGTAAAAGAGCTTTTAGTTCAGACAACAGCAGCAGCTTCCTCTTTACTCCCAAAAAGCGAAGATGAAGAAGGCGAAGCgcaagaaaaattttcacttaTTGATTGTAGGGATCGGCAAAAACGGCTTAATGGTGAAAACACAGAAACTGtaaagcagcagcagcagcagcttgCCATGATGGTGATGGCTTTCCACACACAAAATATGCCCAATACAATAATGACATTTAACATGTTAGACGATAATGCGGCGGCCGATTACCCTGCCATGGAAAATAGTTTATCAACCAAAAGTTTTACAGCCAAAGagcataaaaaaactaaacgCAGCCctgcttttaaaaagaaaaaggcCAGCTTGAAAAAAACCAAGGCCGATAATGCAAAAAATGATGAGCAGTCTCTTAATTTAAAGGCCAGTCCATTAAACAACCACGTTTCCAATCATTATAGTGCTTCAAGCGGCGGAAGGCTTAAAAACAATTATGAAAGTGATAAATTTAGTTTAGATACAAATCAGCAAAATTACGGCAGCAGTGATATTGATGCTGACGCTCATAGAAACGAAGATAATACGCAATTAAATGAGATTAAATCAGTAAATGCCATTAAAAACAACTGCGAATCAATTAATGATAACAATGATATAACAAAACCTCAGATATGCAATTATAATAATACTACCGACACTGGTAAGTAG
Protein Sequence: MFFDQNEEGENNTNMQSLGNLTSAIQLTHQQQDCSKIKQTFVEKNADVTSSNVPAIIFKCKNCDFFGQLKQEVEAHNAILHPNCDSSDVISIPTNPVAIQAFQAAMAAATLAAVSQATKTSLTPSPSASPNLTQTNMNTAKQDNEDYLCPVAVKRECLDLDESELLSEDPTAALNEPSASTEIIERQTTITQVKQSNGVQCPLCQNYFTKKTTLETHLMTVHSVNKDGLARLLLLVDTSIWQSEETCLDSRPTQHTVGEASTSSSVSAISDTTITSTKPPLAGYELSLCQQCGSSFKHEQQLLQHAQKMQHYTMQKGEYICLAFNSVRNPCKMQFPSLTAMFNHYNDTHMRLVISERHVYKYRCKQCSLAFKTQEKLATHTLYHTMRDATKCAMCQRNFRSTQALHKHMEQIHGQTTSSDSNTECVSPRVVSPLDCETSKPMSGICRTPNTIEKLENESSRSVTPGPEACPPTQSPGSIQNEPQNSPSPSTSTQQQPQQQMSAITALINQHQQNAAPSELVHHLQMQHQQFQNLPALHNLQHMQQQFPQFAAAIAASGMPINPVEMLNLMQFHHLISLNFMNLAPPLIFGGNAAAAAAAASSVTGSNSTTPANVPSSTVSKPAGHISATTDPTASLSNLCTNTTPTSSISALPNVDVSTQILQQQQQQISPVASNSQLLNNQKRARTRITDDQLKILRAHFDINNSPSEESILEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQAKVMPLTEQVQHHQLQIPSRPSSTHSISNISEYSNQQQQQMESKQREESDTLRSQASSAASSTFPLDVQIKTEPGEDLTTMPTSVSVEGSTTIPLTKFLKQQQQQQKVRFPSLDQQEHDLMMMSEQHLSSVVASQQQQQHATPSFYNSYETKSESESSDMHSRPHTPNSNTTSNLYASMNDLLSQQLENIPLNQMGPPKKFQINPNSNPCSSNISTTPTDRNVQVGVSGTSSSSSIIGSTGSSGITVSSKLFEKHSPSAQYDNNSNSSNSSTTSSGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNSLYETEEKKQNINYACKKCSLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQNLSSEDSNSSIDINSAAAAALLAHHHPVVGVAAGLGKNTPSAREFSPVPSNATTPPRDQENSSSTEHQKFLCDKCKLTFTHFDHLREHQLMHLVNPNLHMPSEAHTTASAAAAVAAYGPFGSILQSLQQAAHLQQAAAANSATQQPASKKRKYSETSSNADDLSSIGGFSLTGADYDSHAKKYNFLYQYFLQNEANSDIRQQFHNQDSAELNMEFLANYYQQTEVKKRTNYEFLFQYYVRNEQQANANFELPDSKPNIEFLLQYYQLYESKKFFQLEASPQRTHDGPSMQSCIDTSQHNINVSSSSNNSSRPASNGSDRSSSPSGSGINEESNGGGVVDNIENEKHSPLMATYNNEHKTRSNGQHCSNNNNNNDLLINVEHNICQTDTRNERLNIGNAKKLEEQMDQLDGLQEVNNQANSNHGPESSPTRLMSAMTPGLGSYYQNLEDFLDATMIENHSQTLTFPTETNSSANEAAKILEATLNSKSQTEQAAIPENANPKQTNKRLRTTILPEQLNFLYECYQNESNPSRKMLEEIAKKVNLKKRVVQVWFQNTRAKDKKSRNQKRQHFSNISDDNSNSSSVLNNNLKTTISSRTNLATSAVSEASNDIIRDCNLCQVTQVNIQQHAFTVEHIHKVKELLVQTTAAASSLLPKSEDEEGEAQEKFSLIDCRDRQKRLNGENTETVKQQQQQLAMMVMAFHTQNMPNTIMTFNMLDDNAAADYPAMENSLSTKSFTAKEHKKTKRSPAFKKKKASLKKTKADNAKNDEQSLNLKASPLNNHVSNHYSASSGGRLKNNYESDKFSLDTNQQNYGSSDIDADAHRNEDNTQLNEIKSVNAIKNNCESINDNNDITKPQICNYNNTTDTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01400000;
90% Identity: iTF_01400000;
80% Identity: iTF_01074261;