Nfer004005.1
Basic Information
- Insect
- Nowickia ferox
- Gene Symbol
- GIS1
- Assembly
- GCA_936446695.1
- Location
- CAKZFO010000027.1:5223952-5225361[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.06 5.9 8.5 1.1 1 23 181 203 181 203 0.98 2 9 0.00034 0.034 15.6 1.0 1 23 209 232 209 232 0.95 3 9 0.00031 0.031 15.7 1.3 3 23 241 264 239 264 0.92 4 9 0.0001 0.0099 17.3 3.0 1 23 284 306 284 306 0.97 5 9 5.5e-05 0.0054 18.1 1.5 1 23 314 336 314 336 0.98 6 9 2.2e-05 0.0021 19.4 1.6 1 23 342 364 342 364 0.98 7 9 0.00046 0.046 15.2 0.1 1 23 370 393 370 393 0.96 8 9 0.00096 0.094 14.2 0.5 1 23 399 421 399 421 0.95 9 9 1.7e-07 1.7e-05 26.0 2.0 1 23 427 449 427 449 0.98
Sequence Information
- Coding Sequence
- ATGCGAAAACCTTCAATCGAAACCGTGCAGAATTTCTGTCGAGCCTGTCTTaaggaactaaaaaaaatacaatttaaaatatccaatttaaatttgcaaataagacgATGGTTAGAAGATAAAACTTTAGATAACCCTATATCGCATGATATTTATTCCAATAGCATTTGTCAGTCATGTAGAAATAAGTTGGAAGAATTATTAGAATTTCATCTTATGTGCAAACAATCAAGAATGACTGTGGATAAATTGTTTGCAAtggaacaaaataaattaaaggatAATCCACATATTGAGCCCTTAATATGCAAAAGTATTTTAAACTTGACTGAATCAAAAAACAGTAACTATCTTGAAAACCTTGGGTTTTCGGATAATGTCCCTGAAGAAAAAGATGATATCCACTTCAATTCGGCCGTTGATGTTGAAATTAAAGATGACCAAACTAATTTAAAAcagataattaaaaacaaatgctCGGCAAATACTGACATCAAATTGTCAAATTCCAAGGCGGATAGAAAAAGGTACACGTATTCATTTCGTTGTGATCAATGCAAATATCGTGGCGTAAGCCAGCAATTCTTAGACATCCATAAGCGTATTCATTACGGTTTAAAGCCATATCAGTGTCCCCAGTGTGATGATTCATTTAGCAAATATACAACACTTCTTAAACATCTTAACGATAATCATGGACAAAAGGAACTAACAATAATTTGCGAGCACGAGGAATGTGGCAAGGAATTTACTAGCAGCCGGAGCTACAAAGATCACTATCGTCAAAATCACTTACCGCAACAGACAAGCGAAAAACAAGATAAATGTGCAACAAAAAGTCCGCAACGACATGTGTGTGAAGAATGTGGAAAGTCTTATACAAAATTGCAGACTTTTAAAGAACATCAATATACCCATCGATCCAAAGAATTCTATCCATTCCAATGCGAAATATGTGACAAGGCATTTGTAAAGCGAAGAACATACAATGAGCATAAGCTCAGACATGCTGGCATTAGAAATTTCGAATGCCCCCATTGTGGAGCTAAGAGAACTACGAGAAAAGAATTAAGAGAACACATGAACAGCCACACTAGGGAACGCCAGTATCCCTGTCCAAATTGTCCCATGATTTTTTATAGAACTAGCAACCGTCGCGTCCACATCGATGTAGTACATCAGGGCATACGACGTTTCGCTTGTCGTTATTGTGACCAAACATTCGGTAAAGGGGACAACTTAAAAAATCATGAATTACTACATACAGGAGAGAAGCCGCATGTCTGCTCAGAGTGTGGAAAACGATTTGTTCAAAAGGTGTCGCTAAGGTTGCACATGAAAAcacattgcaaataa
- Protein Sequence
- MRKPSIETVQNFCRACLKELKKIQFKISNLNLQIRRWLEDKTLDNPISHDIYSNSICQSCRNKLEELLEFHLMCKQSRMTVDKLFAMEQNKLKDNPHIEPLICKSILNLTESKNSNYLENLGFSDNVPEEKDDIHFNSAVDVEIKDDQTNLKQIIKNKCSANTDIKLSNSKADRKRYTYSFRCDQCKYRGVSQQFLDIHKRIHYGLKPYQCPQCDDSFSKYTTLLKHLNDNHGQKELTIICEHEECGKEFTSSRSYKDHYRQNHLPQQTSEKQDKCATKSPQRHVCEECGKSYTKLQTFKEHQYTHRSKEFYPFQCEICDKAFVKRRTYNEHKLRHAGIRNFECPHCGAKRTTRKELREHMNSHTRERQYPCPNCPMIFYRTSNRRVHIDVVHQGIRRFACRYCDQTFGKGDNLKNHELLHTGEKPHVCSECGKRFVQKVSLRLHMKTHCK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01397834;
- 90% Identity
- iTF_01397834;
- 80% Identity
- -