Basic Information

Gene Symbol
-
Assembly
GCA_936446695.1
Location
CAKZFO010000112.1:85496-105407[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 8.8 8.7e+02 1.7 0.1 2 23 369 391 368 391 0.91
2 24 1.3 1.3e+02 4.4 0.0 6 23 400 417 400 417 0.98
3 24 7.1e-06 0.00069 20.9 2.1 2 23 424 446 423 446 0.96
4 24 9.5e-05 0.0093 17.4 0.7 2 23 452 473 452 473 0.97
5 24 0.00092 0.09 14.3 0.7 3 23 482 503 481 503 0.96
6 24 0.057 5.6 8.6 0.6 3 23 509 528 507 528 0.95
7 24 2.5 2.5e+02 3.4 0.1 2 23 864 886 863 886 0.92
8 24 4.5 4.4e+02 2.7 0.3 6 23 895 912 895 912 0.96
9 24 4.4e-05 0.0043 18.4 2.3 1 23 918 941 918 941 0.98
10 24 0.0022 0.21 13.1 1.2 2 23 947 968 946 968 0.96
11 24 0.00015 0.014 16.8 0.8 2 23 974 995 973 995 0.97
12 24 0.0051 0.5 11.9 0.4 3 23 1002 1022 1001 1022 0.97
13 24 0.0019 0.19 13.3 3.9 2 23 1031 1052 1030 1053 0.93
14 24 0.00065 0.064 14.7 0.4 1 23 1062 1085 1062 1085 0.98
15 24 0.16 16 7.2 0.2 2 17 1092 1107 1091 1108 0.87
16 24 2.1 2.1e+02 3.7 0.1 2 23 1502 1524 1501 1524 0.96
17 24 5.4e-06 0.00053 21.3 2.2 1 23 1556 1579 1556 1579 0.98
18 24 2.9e-05 0.0028 19.0 0.3 2 23 1585 1606 1585 1606 0.96
19 24 7.3e-08 7.2e-06 27.2 1.2 2 23 1613 1634 1612 1634 0.97
20 24 0.0015 0.14 13.6 0.8 3 23 1641 1661 1640 1661 0.96
21 24 0.0025 0.24 12.9 3.0 3 23 1671 1691 1669 1692 0.94
22 24 1.2e-07 1.1e-05 26.5 0.3 1 23 1701 1724 1701 1724 0.98
23 24 0.0001 0.01 17.3 0.2 2 23 1731 1752 1731 1752 0.98
24 24 0.0072 0.7 11.5 4.1 1 23 1758 1781 1758 1781 0.98

Sequence Information

Coding Sequence
atgaattgcCTTTTGTGCTTGGAAGTAACTGAAAGTTATAAGGATTTGATAGTTTTTAACTCCAGCGAATGGCAGGAGCTAAACATGCAGTGTATTATTGAAAAGTATCTTTGGAAATTGGAAGTTTTAAATAGCCAATCCTATATATGCCAAGCGTGTTGGCAAGAATTATACAGTTTCCATaagttttacttaaaacttGAAAAGGCCCGCTCAAATTTAAGTGATTTAGTGAACACTGAAGAAGTTACCAAAGAAGCTGTTGAAGCAGGAAACGGAGAAAAAGCTGAGAAAATTGCCAATATTGGAAAAGTACCAAAACCTGAaccagaaattttattttttagagagGAATATCctacagatatttttgaaaaggaAGATGAAGGGGAAGCAAATTCTCTTAAAACTAATAACAAGCGTAAATGCTCTGAAAAGAAAAGttcacatgacaaaaaaaatgaaaaaaatagttcGAGGAAAAGATCCAACAAAGAACAAAGTAATACTGAAATAAACGAACTAAAATCCAATGAAAATCCTGATGGAATTGACATAAAGTTAGAAgttgaaagaaaagaaaacgatAAGTCCGATGAAAATGAATCTGAAATGGattcagaattaaaaaaaatagaaaatgatgCTGAAGACAACAAAATGGAAAATGAGGAAGAATCTATTTGTCATAAGAAAAGTATTAAGCGTAAATGCTCTAGAAAGAAAAGTACAAATGATAACAAAATTATTGCAAGAAAAAGTTCGAGGCAAAGATTCAGCAAAGACAAaagtaaaattgaaattgaaataaaaaaactgaaatccGTTAAAAGTCCAGATGAAATTGACAAAACATTAGAAGTTGAAAGAATAGAAAAAAACGTTAAAGAGAACTGTATGCAATTCGATGAAAATATAGATGAACCTAAAAcaaaattagaattaaaaacaacagaaaatgaggctaaacaaaacaaaatggaagAAGACGATCAGAGTGATAGTTCCACAAATGACGATGATACTTCCTCCGATGAAGCTGATttagatcaattaaataaattatcggATGAAGACAAATTCATAgccgaaaattttaaaatcacttGTGACATTTGTCAAATCTCACAAGAAACATTTTCCGCAGTGATGAAACATTACAAAGAGATACACAATCAGCGTGGATATGTTAAGTGCTGCGGTAATAAGTTTGGGACTCGTGTTGAATTAGTGGACCATCTTAATGTCCACCAAAATCCAGAATATTTGAAATGCAAATACTGTACCAAAACGTTTACTAAACGTGCAAGCCTGAAGGTACACATAAAACGTGCTCATGAGGAAAACAGGGCGGAATGCGACATTTGTGGCAAAAGCTTAGCAACTGAATTAGCTTTAAAAAGACACATGTGTACACATAATAGTGAAGATAAAAGGGTATTTTGCAAACAATGCGGTAAATCCTATTTATCTAAATACTCCCTAGTCAATCACATGCGAGCTGTTCACATTACAAATGTAATTTGCCATTTATGTGGCAAATCTATTTATCTATACGACTTCACACGTCATATGGCAGAGCATGAAGGAAAACCTCTACCAAAGGAAGTTGCAAATATTCGATCCTATATATGCCAAGCGTGTTGGCAAGAATTATACAATTTCCATAAGTTTTACTCAAAACTTGAAAAAGCCCgttcaaatttaaatgatttattgATCACTGAAGAAGTTACCAAAGAAGCTGTTGAAACAGGAAACGAAAAAGAAGCTGAGAAAATTTCTAATATTGCAAAAGTATCCCAACCTGaacctgaaattttattttttagagagGAATATCCTACAGATATTTTTGAAGAGGAAGATGAAGTGGAAGCAAGATCTCTTAAAACTAATAACAAGCGTAAATGCTCTGAAAAGAAAAGttcacatgacaaaaaaaatgaaaaaaatagttcGAGGAAAAGATCCAACAAAGAACAAAGTAATACTGAAATAAACGAACTAAAATCCAATGAAAATCCTGATGGAATTGACATAAAGTTAGAAgttgaaagaaaagaaaacgatAAGTCCGATGAAAATGAATCTGAAATGGattcagaattaaaaaaaatagaaaatgatgCTGAAGACAACAAAATGGAAAATGAGGAAGAATCTATTTGTCATAAGAAAAGTATTAAGCGTAAATGCTCTAGAAAGAAAAGTACAAATGATAACAAAATTATTGCAAGAAAAAGTTCGAGGCAAAGACCCAGCAAAGACAAaagtaaaattgaaattgaaataaaaaaactgaaatccGATAAAAGTCCAGATGAAATTGACAAAACATTAGAAGTTGaaagaatagaaaaaaatgCTAAGGAGAACTGTATGCAATTCGATGAAAATATAGATGAACTCAAAACAGAATTAGAAttacaaacaacagaaaatgacGCTAAACAAATCAAAATGGAAGAAGACGATCAGAGTGATAGTTCCAAAAATGACGATGATACTTCCTCCGATGAGGCGGATTCAggtcaattaaataaattatcggCTGAAGACAAATTCAtagccgaaaattttcaaatcacttGTAACATTTGTCAAATCCCACTGGATACATTTGCCGCAATGCTCAAGCACTACAAAGACGAACACAATCAGCGGGGGCATGTTTCTTGTTGTAACGCTACCTTTTACCTGCGTAATCAATTAATGGATCATATCAACTTCCACCAAAATCctgaatattttaaatgcaaacactGTGACAAAGTGTTGGCCAGTCGCGCAACCCTAAAGAATCATTTAAAAAGAGTTCATGAGGGAGAGGTTTCTGAGTGTGACATTTGTGGCAAAAGATTAGCAAATAAAGCGTGTCTGAAAATGCACAAGTTAATGCataaaactgaaaatatatCTTGCAACCAATGTGGTAAATCTTTCTTATCTCAATACGCCTTAAGGAATCACAAACGAATTCACtacaaaaagcttaaaatttgcGATTTATGTGGTACATCTATAGCAACTGCACATGCCTTCAGACGTCATATGTTACAGCATGAAGGAAAAACTCCACCAAAGGTGAGCTGTAAAATGTGCGATCGCCAGTTTTCAGATAAGGGTTGCTTAAATCGACACGCTAGTTTGCATCATCCACCAGATGGAGttaaaactgaatttaaatgtgctGAGTGTCCAAAAGTGTTTGCTGCTGATTTTTATCTTAAGAGCCACATGCAAAAAATGCACTATAATCCACATGTAGGAAAATGTACATTGTGTGATAAAACATTTAAAGGACGCATGGCCCTaaagGAAGTTTTAAATAGTCAATCTTATATCTGCCAAGAGTGTTGGCAAGGATTATACAAATTCCATCAGTTTTactcaaaacttaaaaaagtccGTTCCAATTTAAATGATTCCTTGAACACAAAAAAACTTACCAAAGAAGCTGTTGAAACAGAAAACCAAGAAGATgctgagaaaatttataaaattattgcaaattgtGATACACAATCTGAAACTGAAAATTCACTTTTTGGTGAAAAGAAAGATGAGGAGGAAAGAAATACCAACCGTAAATGCTCCAAAAACATAAGTTCACATGACAgaaacattgaaaaaaataattccagGAGATGCAACAAAGAACAAAGTAATACTGAAATAGACGTACTGAAATCTGATTCAAATCCTCAAGAAATTGGCACAAAATTGGAAATAACAACAATGGAAGGCAACAAGTCCGATGAAAATGGAGCTAACTTTGGCTcaaaattagaattaaaaacaataGAAATTGATGCTAAAGACAACAAAATGCAAGATGAGGAAGCCTCAATTTGTCTTCAAAGAAGTACTAGACGTAAATGCTCTAGAAAGAAAAGTACAAatgatagaaaaaatattgcaagcAGAAATAGCGTGAGGAAGAGATCGaataaagaaataagtaatatTGAAATCAACAAATTGAAATCCGATGATAATCCAagtgaaatttgtacaaaatcgGAAATAGAAAACGAGAAGTTTGATGCCAAAGTTCACAAAATGGAAAATGAGGATGAATCTATTTGTCTTAACAAAAGTGCTAAGCGTAAATGCTCTAGAAAGAAAAGTTCAACTAATAACAAAATGATTGCAAGAAATAGTTCGAGGCAAAGATCCTACAAAGAAAAAAGTGATACTGAAATCAAAGAATTTAAATCCGTTGCAAATACAGATGAAATTGACGAAAAGTTAGAAATTGAAAGAATGGAAAACGATGCAGGAGAAAACAGAATGAAATTCGATAAAAATTTAGATGAACTTGAAAcaaaattagaattaaaaacaacagaaaatgatGCTAAACAAAACAACATGAAAGAAGACGATCAAaattgtagtttaaaaaatgatGTTGAACCTTCCTCTAATGCGGCAGATTCAGTCAAATTAGATAAATTATCGGCTGAAGACAAATTCAtagccgaaaattttcaaattacctgTAACCTTTGCGAAATCCCATTGCCCACGTTTGCCGCAATGCTCAAGCATTACAAACGCGAACACAATCAGCGAGGGCGTGTGTCTTGTTGTAATTTTAACTTTTACCTGCGTGTTCAATTAATGGATCATATCAAGTTTCACCAAAATCCTGAacattttaaatgcaaacactGTGACAAAGTGTTCCCTAAACGCGCAGGGCTAAAGACTCATATACAGAAAGTTCATGAGGCTGAGGTTGCTGAATGTGACATTTGTGGCAAAAGTTATACAAATGAAACGGGTCTAAAAAGGCACAAGTTAATACACAAAACTGAAGATATGTTAACTTGCAATCAATGTGGTAAATCTTTCTCATCTCAATATTCCTTAAAAAATCATATACGAGTCCACTTCAAAAAGCATAGAATTTGCGATTTATGTGGTAAATCGATATCAACGCCCCATGGTTTCAGGCGCCATCTGTTACAGCATGAAGGAAAAGCTCCACCAAaagtaaattgcaaaatttgcggCCGCATCTTATCAGATATGAGTTGTTTATCTCGACACATGAGTTCGCATCATCCACCGGAAGGTGCGATAACTGAATTTAAGTGTCCCGAGTGCCCAAAAGTGTTTGCAGTTAAATATAACCTTAAAACGCACATTAGAAGTGTGCACGAAAGTAAATACGCAAGAAAGTGTACGATTTGCCAGAAGACATTTAAAGGACCCGTCGCCCTAGCggaaCATATGTCTAGGCATATGGGTGAACCTCTATACACGTGCAGCTTTTGTCCTAGACAATTTTATTCCAGTGGAAACATGCATTCACATCGCAAAAGAGAACATCCAGTAGAATGGGAGAAAATATCTAGAGAAAATGGGCcacaaaaaacaacagaaaatcaATAA
Protein Sequence
MNCLLCLEVTESYKDLIVFNSSEWQELNMQCIIEKYLWKLEVLNSQSYICQACWQELYSFHKFYLKLEKARSNLSDLVNTEEVTKEAVEAGNGEKAEKIANIGKVPKPEPEILFFREEYPTDIFEKEDEGEANSLKTNNKRKCSEKKSSHDKKNEKNSSRKRSNKEQSNTEINELKSNENPDGIDIKLEVERKENDKSDENESEMDSELKKIENDAEDNKMENEEESICHKKSIKRKCSRKKSTNDNKIIARKSSRQRFSKDKSKIEIEIKKLKSVKSPDEIDKTLEVERIEKNVKENCMQFDENIDEPKTKLELKTTENEAKQNKMEEDDQSDSSTNDDDTSSDEADLDQLNKLSDEDKFIAENFKITCDICQISQETFSAVMKHYKEIHNQRGYVKCCGNKFGTRVELVDHLNVHQNPEYLKCKYCTKTFTKRASLKVHIKRAHEENRAECDICGKSLATELALKRHMCTHNSEDKRVFCKQCGKSYLSKYSLVNHMRAVHITNVICHLCGKSIYLYDFTRHMAEHEGKPLPKEVANIRSYICQACWQELYNFHKFYSKLEKARSNLNDLLITEEVTKEAVETGNEKEAEKISNIAKVSQPEPEILFFREEYPTDIFEEEDEVEARSLKTNNKRKCSEKKSSHDKKNEKNSSRKRSNKEQSNTEINELKSNENPDGIDIKLEVERKENDKSDENESEMDSELKKIENDAEDNKMENEEESICHKKSIKRKCSRKKSTNDNKIIARKSSRQRPSKDKSKIEIEIKKLKSDKSPDEIDKTLEVERIEKNAKENCMQFDENIDELKTELELQTTENDAKQIKMEEDDQSDSSKNDDDTSSDEADSGQLNKLSAEDKFIAENFQITCNICQIPLDTFAAMLKHYKDEHNQRGHVSCCNATFYLRNQLMDHINFHQNPEYFKCKHCDKVLASRATLKNHLKRVHEGEVSECDICGKRLANKACLKMHKLMHKTENISCNQCGKSFLSQYALRNHKRIHYKKLKICDLCGTSIATAHAFRRHMLQHEGKTPPKVSCKMCDRQFSDKGCLNRHASLHHPPDGVKTEFKCAECPKVFAADFYLKSHMQKMHYNPHVGKCTLCDKTFKGRMALKEVLNSQSYICQECWQGLYKFHQFYSKLKKVRSNLNDSLNTKKLTKEAVETENQEDAEKIYKIIANCDTQSETENSLFGEKKDEEERNTNRKCSKNISSHDRNIEKNNSRRCNKEQSNTEIDVLKSDSNPQEIGTKLEITTMEGNKSDENGANFGSKLELKTIEIDAKDNKMQDEEASICLQRSTRRKCSRKKSTNDRKNIASRNSVRKRSNKEISNIEINKLKSDDNPSEICTKSEIENEKFDAKVHKMENEDESICLNKSAKRKCSRKKSSTNNKMIARNSSRQRSYKEKSDTEIKEFKSVANTDEIDEKLEIERMENDAGENRMKFDKNLDELETKLELKTTENDAKQNNMKEDDQNCSLKNDVEPSSNAADSVKLDKLSAEDKFIAENFQITCNLCEIPLPTFAAMLKHYKREHNQRGRVSCCNFNFYLRVQLMDHIKFHQNPEHFKCKHCDKVFPKRAGLKTHIQKVHEAEVAECDICGKSYTNETGLKRHKLIHKTEDMLTCNQCGKSFSSQYSLKNHIRVHFKKHRICDLCGKSISTPHGFRRHLLQHEGKAPPKVNCKICGRILSDMSCLSRHMSSHHPPEGAITEFKCPECPKVFAVKYNLKTHIRSVHESKYARKCTICQKTFKGPVALAEHMSRHMGEPLYTCSFCPRQFYSSGNMHSHRKREHPVEWEKISRENGPQKTTENQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-