Nfer020133.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nowickia ferox
Gene Symbol
tbx2
Assembly
GCA_936446695.1
Location
CAKZFO010000164.1:1693857-1704016[-]

Transcription Factor Domain

TF Family
T-box
Domain
T-box domain
PFAM
PF00907
TF Group
Unclassified Structure
Description
The T-box encodes a 180 amino acid domain that binds to DNA. Genes encoding T-box proteins are found in a wide range of animals, but not in other kingdoms such as plants. Family members are all thought to bind to the DNA consensus sequence TCACACCT. they are found exclusively in the nucleus, and perform DNA-binding and transcriptional activation/repression roles. They are generally required for development of the specific tissues they are expressed in, and mutations in T-box genes are implicated in human conditions such as DiGeorge syndrome and X-linked cleft palate, which feature malformations [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.9e-63 5.5e-60 203.4 0.0 28 182 1 154 1 154 0.99
2 2 2.9 8.3e+03 -2.5 0.5 135 147 181 193 164 214 0.50

Sequence Information

Coding Sequence
ATGTTCCCATCCATGCGACTGTCACTGTCTGGCCTTGAAGATGAAAGTAATTATTGTATATTATTGGAAATGGTACCGATTGGCGACTGTCGTTACAAATTTTCTGGCTCGCAGTGGGTGCCAGCTGGTGGTGCTGAACCTCAATCACCGCAGCGCATGTGCCTGCATCCTGATAGTCCTGCAACGGGTGCTCATTGGCAAGCACAACCGATATTGTTTAATAAAGTGAAACTGACCAATAATACGCTGGATAATAATGGACATATCGTTTTGGCCAGCATGCACAAATATCAACCACGCATACATGTGATACGTACATCTGATTTAGCACAAATACCCTGGGCACCTCAGCAAGCATTTGTTTTTCCTGAGACAGAATTTGTTGCAGTTACCGCTTATCAGAATGATCGAATAACTAAGCTAAAAATTGATAACAATCCTTTTGCCAAAGGGTTTCGTGAAACTGGTCAATCACGTTGTAAACGCAAAATGTCTTCATCACCTACTGCTGAGGATCAgccgcatcatcatcatcaacaacaacaacaacaacaacaacatcagcagcagcagcagcagctacaATTACAACAACATCAACTTGATATCATGTCTCCAACAAAATCAGCAACTACCGCAATCAGTGAGTCGGGATCATCAATTTGTTTGGATAAACCAGTGACGGCGTTCTTTAATGAACATCACAGCAGCCTTGTGGATGTAGTAGATGCAATATCACCACCATCATCAGCAGCAACATCGCCTCAAATTAAACGATTACGTTCGAATGATTCGGCGTGTTCTTTAGAGACAACAAACGAAACCAGTTCGGGAGGCAACATGTCATCATTGGATTATGTTAACAGTGCAAGCAACATATTTCAACCACAGTCACCAATTGCTGCTGCCGGCAGCAATAGCGGTGGCACTAGTGGTTGTAATGCAACATCCGTTGCTTTCATGCATCACTTCCAGCAAAACATGCAATCGTTGCTACGACCTTCACTGGTCGATTTAGCATGTTCATATTTTGCCCGTCCCCAGCCTTTGTATCCCCAGCATGTTTATGCTGTAGCAGCACAACATGAAGCATTAGTTGCGGCTGGTTTGCCACAGCCGCCACTGCTACCTCATAATATGGGTGATATGCCTCAACATTTGTCTCTACCAAGCAACGATGGCAGTACAAGTGTCGGTAGTGTTGTTGGTTGCAGCGGTGAATTGCCAAATCGTGTTATGGCCATTAACTCAAATACCACCTTAGAATGCATAACAAACGATGCCGATCTTTCTTCATCCGATTCATCATTAATACAAGACGATACTGCAACACCGGTTACAACACCAACAATGTACGCCACTTGCAATTCAAATGATGATGCATTATACCAATCCCAAACCCAATCACCATCAGGCAATAGCAGTAAAGACAGCAACAGAACGAGAAACAGCAATGGCAAcggcagcaacagcaacagcaacgcCAACAGCAATACCAACCATAAAAAGAAAGGCTTTAGCATCTCGGCCATTTTAGGTGGTGGCAGTTAG
Protein Sequence
MFPSMRLSLSGLEDESNYCILLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMCLHPDSPATGAHWQAQPILFNKVKLTNNTLDNNGHIVLASMHKYQPRIHVIRTSDLAQIPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSSSPTAEDQPHHHHQQQQQQQQHQQQQQQLQLQQHQLDIMSPTKSATTAISESGSSICLDKPVTAFFNEHHSSLVDVVDAISPPSSAATSPQIKRLRSNDSACSLETTNETSSGGNMSSLDYVNSASNIFQPQSPIAAAGSNSGGTSGCNATSVAFMHHFQQNMQSLLRPSLVDLACSYFARPQPLYPQHVYAVAAQHEALVAAGLPQPPLLPHNMGDMPQHLSLPSNDGSTSVGSVVGCSGELPNRVMAINSNTTLECITNDADLSSSDSSLIQDDTATPVTTPTMYATCNSNDDALYQSQTQSPSGNSSKDSNRTRNSNGNGSNSNSNANSNTNHKKKGFSISAILGGGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00760105;
90% Identity
iTF_01399464;
80% Identity
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