Nmel007251.1
Basic Information
- Insect
- Nomia melanderi
- Gene Symbol
- -
- Assembly
- GCA_003710045.1
- Location
- NW:522951-530357[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.19 11 5.7 1.0 2 20 149 167 148 169 0.91 2 20 0.00017 0.011 15.3 0.5 1 21 176 196 176 197 0.94 3 20 0.00071 0.043 13.4 3.8 1 23 214 237 214 237 0.92 4 20 0.00014 0.0086 15.6 2.3 1 23 501 524 501 524 0.96 5 20 0.0013 0.078 12.5 2.2 2 23 557 578 556 578 0.96 6 20 0.034 2.1 8.1 2.0 1 22 703 724 703 724 0.96 7 20 0.028 1.7 8.3 0.8 1 23 731 754 731 754 0.91 8 20 0.076 4.6 7.0 3.3 1 23 764 787 764 787 0.91 9 20 0.041 2.5 7.8 0.0 2 20 810 828 810 830 0.92 10 20 0.4 24 4.7 6.0 1 23 837 860 837 860 0.93 11 20 0.0012 0.075 12.6 3.1 2 23 872 894 871 894 0.93 12 20 0.16 9.7 6.0 0.8 1 21 935 955 935 956 0.92 13 20 1.8 1.1e+02 2.6 1.0 1 23 963 986 963 986 0.84 14 20 0.001 0.062 12.9 0.8 1 21 1049 1069 1049 1070 0.95 15 20 0.0075 0.46 10.1 0.4 1 23 1077 1099 1077 1099 0.96 16 20 0.028 1.7 8.4 0.3 1 23 1109 1132 1109 1132 0.92 17 20 0.00051 0.031 13.8 0.3 1 20 1155 1174 1155 1176 0.94 18 20 0.00014 0.0083 15.6 0.2 1 23 1183 1205 1183 1205 0.98 19 20 0.063 3.8 7.2 0.6 1 13 1214 1226 1214 1237 0.75 20 20 7.1 4.3e+02 0.8 0.2 3 17 1335 1349 1333 1350 0.85
Sequence Information
- Coding Sequence
- ATGGCTCGAGTTTATGTTTATGAACGCCCAGTTGACTCTGTTTTGACGAATGTGACATTCTACGAGAATTTATATCGACGTACAGAAGAGATACAGATTAAAGAAGAACCGCATGACATAGATGAGAATGATCAAGGCAATACTTTTTCACCAAATACTGACGTAACGTCTACCACTACAGGAGAATCAACTGTTTTAGAAACTCGATCGGCGgactatataaataacaaagaaaatgaacTTGTATTGTCCAAAGATTATACTGATACAGAGAATTCAATAGCACAGACGCCTAGAAGGAAACGTACACGTTCAGAATTTGAAAATCTTAAAGAACAAGATACACCTAATTCATTTAGAGAATTTAAACGTGTTCGGTTTACAAGTCCTACTGTAATTCATTACATTCCCGAAAGGAATTCAAAATCATCTATAAATGGGAAAAAATGCGATATATGTTCGTTGACCTTCAAAAAAGCAATAGCACTGAAGTGTCATATGGATTATTACAATGGATACTCTGGTTATATTTGTGATAAATGTAATGCGGTGTTCAAATcacaagttttattaaaaaaacacaaAAACCGATCAGCCTGTCAGAAGcgtaataataaagataataacGATACAAGAATGTTTTTCTGTCATTTCTGTGAGCGACCGTTTAGACGCAAACCAAGCTTGCAAGCTCACATATTTCATGCACattcaaaattaatgtttagtcttgaaaaagagaaaaatgtagTTCCATCTCCGCAAAATACCGGCAGTCCCgcgattaaaaaaatgaagcaaACAAGTATCGTAGATTTTCTTCGAAGAGTTGCAGAAAAAGAAGCACTTACTTCTAGAGAAAGCGTTAATCTTAAAGAAAAGCATTCCAAAAAAGTTACACCTAAGCAGAATGGggtattacattcatttttggGACCACCTCAAGAAAATAGAACAACTAATAACAAAACTTCTAGTTCTAATACTGATTCCTCTCGTGGTAAGAGACCATTTGTTGAGATACACGTGGACTCTGATATGGTGACGTttttattgaagaataatgtaaaaactgaaatgaaaGAGTTATCTTCTGACTCACCATTGCATAATACATCCTATAATCTTAGAAGAATCAGAAGAAGTAGTGATCATTCATTAACTGATTCGAATATGTCACCAGCGTCTAGAACTGGTAGGAAGATACACTCAGTTGCTACACCTAAACACGGACAAAGAGACTGGCCGCTAACAGACCAACAACTGAATGATaaatttaaaactaaaaaatgtTCAGTTTATTTGATTAGATGCGATACagatattaagaaaaataaggaACTTAATGGCGTTGAACGAGATTCTAACAAGAATACTAAGCGAAAAAGAATAGAAGTTCCATTGGTAAGAATGAATAACGGTGTAAAAGTTCAGCAGGTTGATCAACTCTTACCAGGTTCACAGAAATTGAATACAATTCGAAATGGCAAGCGGACGATGTTTCGGTGTAAGGTTTGCAATAAATCCTTCCCCGCAAAGGAAAGCTTGcatgaacatttgaaattgcGTCATGTGTTCTATATATCAAGTATATGCAATGCTCGCAACAGAACGATGAGTAAATTACTGAAACATTACCTTTATCGACATACTATTCTCAGACGAATGAAGTGTTGTGTGTGTTTTGAGAGATTTAAGTCCCTTGTGTTATTGAAACGACACATGGTTGTACATTGCATAAGAGTAATCGAATCCGAGGAAGATAAACCATGTActaaggaaatatttaaatgtaacttAATGAAAAAGACCAATCGCTGCGAAGCTTGTGGTAAGCTATTTTGGTTAGAGTCATGCTTGAATGAACATGAAAAGGTTTGTCAGagaatgaaagtgaaaataaagaaagaacaTTGTATACCATCCGTGAAAACATCTCCGCCCCCTTCGAATAATCAAGGATCTAATGCGAAATTTAATCGATCTCTTAGCGGGTCTGAATCTGTATGCCAGTCAGAGTCGGTGACACACCAAAAACCGTTATTGAAGGGTGTTGCACTTGTAAAAGGGTATAACATCGATGACAGTGGCTCTGAGAAAGTGAAGTTCCCCTGCACCGTTTGCGATGCACAGTTCCATACATTTCAGAATTTGTGTTTACACGAGCGTACCTATTCCCAGCCAGCTGTATACATCTGCCAGACCTGTGATACAGCGTTCCCCACAAGGAGGATATTGAAACATCATGTATCTGCGACCCATACGCCTATCAAGCTTctaatgtacaaatatttctgtatgtTCTGTACTCAGGGcttttcaaagaaatcaagACTTCAAATTCATATAGGTCACTTCCACGCTAATCAAACACCTATTATACCGAAACCGTGGTTGGACAGCTCGCCCAACTGCAAAGTGGATGCTGTATGCAGTATATGCAACCTGGTGTTCGAATCCAACGAGGGTTTCATCGAGCATACCCTCTACTACTACAAAGGTCAAATGTTCACGTGCACATTCTGTGATCAAACTTTCCACGGAATGTACATGCTTAATCATCACAATAAACTGAAACATTACTCGGAAGACAAGCGCAAATTGTATACTTTGATATGCAACATCTGTAACGAGGGCTTCAACCAGGAATCCCACCTCCATGCGCATAAGCAACACGTTCATTTGAACCGAGTCACCTACAAGCCTTCGTGTCCTCAAGTTAACCCTTCGAGTAACACACAGGATCACACGTACGCGTTAATAAATAGAGATAATGCATCAAGTAGTTTCCCATCCAAAAAGTTCACCTGTAACATTTGCCACCTAAATTTCTTGCGAGAGAAAGACTTATATTTACACAGAATGGAGTACACCAATACCGGGGACTTCCTGTGCAGCTATTGCCCCAGAAGGTGTCCTAACGATACCATTCTAGCCAGGCATGAAAATTTGACCCATATCAGTCGTAATTCCAGCGAAACCTACACGTGTCGTTTTTGCGGCGAAGTAGTCTACACAACCGTAGCACTGAAATGTCATCAGTATCATTTCCACGAAATGAACGAAACGGATTTAAAGAATGAGAACGGTATTCAATTACAGAACACTGTGATGCTTGTCACGTCGAGACCAGACGATGGCAATTTTTCTTGTACGGTCTGTAACATGAAGTTTTACAGTCAGGACAAGTTGAACTACCATTTGCAGGAGTATGCGAACACAGGCACGTACAGTTGTCCAACGTGTAGTCGGAAATTTCCAGAGTTGTACCGCCTAGAAGTGCACAAGCTCGAGCATTCGAACTTGAACTACATGTTGTGCAAATATCGATGCTCTGTGTGCCAAGAGGGATTCCCGAGTCTCTTGAACGTTCAAGCGCACGCGTTGCACTTTCACGGACGCAAAGGTACTAAGAAGACTGCGAGTGAGTCTACAACTGCCAGTACTACCAAAAGAGGACCATACACGTGCGACGTATGCTCGATGTCCTTTGAATCCACGTATTCTTTGAAAAGACACGAAGCACGTCTCTCGAACACAGGCGACTATATGTGCGATTTATGTGGCAGGAGATTCCCTGGTATCGAGTGGTTGAAAGAGCACCAGAAAAGACACGCGGTCAACCCGAAACGACAGAGGTACTCTTGTCCCGACTGTGATGAGACGTTCCAAAGTGTACTTTCTCAGTACCAACATATCGTTCATCAACACGGCAAGCAGAAATGGTTCGGTAAAATTCCTAACCAGAGAAGACAAGGAGCTGCGAAAACTGCCCAAAAAGCACAGAATGGCAAGGGCAAACAAGGCCCAACTACAGGCAACACTGTAAATAAAGAATCCCCCGCCACAGAGAAGTGTGCTAATGAAGACAATGCTTCTCTAATCGAAGAACACCTGCGAAATTCAGGAGCGGAGCTGCTCTCCCGCATGTGCCCCACTTGCAGTACAAAGTACCCAACGTTCAACTCATCCCAGTTTCATTTCGAAGGAAGTCCTGACCGTTGCATTGGTTGCAAGCTCACCTTCACCACGGAAGCGAAGCTTAAACAATATCCGTCGAAACCACATGTGCGAGTCAAGCCTATCAACATGGAAGATGCGCCCTGTCTAACCACGAAGGAAGATCCCGATGTGGTGCCAGTCGTTCTTGACAAGGAATCCGAGACTGCTGAACAGCTTGGAAGACAAAGCAACACCGTCAAATCGGCCATTCATGtttcgtataaaaatttttgtccTATTGTTAAGTATGAATCGGATATATCATCGGAAAAATCGAACGACGAGCCCCCGTCCGACattggaaaattaaaagtcAGAGACTTTGCTACGATGATTTAA
- Protein Sequence
- MARVYVYERPVDSVLTNVTFYENLYRRTEEIQIKEEPHDIDENDQGNTFSPNTDVTSTTTGESTVLETRSADYINNKENELVLSKDYTDTENSIAQTPRRKRTRSEFENLKEQDTPNSFREFKRVRFTSPTVIHYIPERNSKSSINGKKCDICSLTFKKAIALKCHMDYYNGYSGYICDKCNAVFKSQVLLKKHKNRSACQKRNNKDNNDTRMFFCHFCERPFRRKPSLQAHIFHAHSKLMFSLEKEKNVVPSPQNTGSPAIKKMKQTSIVDFLRRVAEKEALTSRESVNLKEKHSKKVTPKQNGVLHSFLGPPQENRTTNNKTSSSNTDSSRGKRPFVEIHVDSDMVTFLLKNNVKTEMKELSSDSPLHNTSYNLRRIRRSSDHSLTDSNMSPASRTGRKIHSVATPKHGQRDWPLTDQQLNDKFKTKKCSVYLIRCDTDIKKNKELNGVERDSNKNTKRKRIEVPLVRMNNGVKVQQVDQLLPGSQKLNTIRNGKRTMFRCKVCNKSFPAKESLHEHLKLRHVFYISSICNARNRTMSKLLKHYLYRHTILRRMKCCVCFERFKSLVLLKRHMVVHCIRVIESEEDKPCTKEIFKCNLMKKTNRCEACGKLFWLESCLNEHEKVCQRMKVKIKKEHCIPSVKTSPPPSNNQGSNAKFNRSLSGSESVCQSESVTHQKPLLKGVALVKGYNIDDSGSEKVKFPCTVCDAQFHTFQNLCLHERTYSQPAVYICQTCDTAFPTRRILKHHVSATHTPIKLLMYKYFCMFCTQGFSKKSRLQIHIGHFHANQTPIIPKPWLDSSPNCKVDAVCSICNLVFESNEGFIEHTLYYYKGQMFTCTFCDQTFHGMYMLNHHNKLKHYSEDKRKLYTLICNICNEGFNQESHLHAHKQHVHLNRVTYKPSCPQVNPSSNTQDHTYALINRDNASSSFPSKKFTCNICHLNFLREKDLYLHRMEYTNTGDFLCSYCPRRCPNDTILARHENLTHISRNSSETYTCRFCGEVVYTTVALKCHQYHFHEMNETDLKNENGIQLQNTVMLVTSRPDDGNFSCTVCNMKFYSQDKLNYHLQEYANTGTYSCPTCSRKFPELYRLEVHKLEHSNLNYMLCKYRCSVCQEGFPSLLNVQAHALHFHGRKGTKKTASESTTASTTKRGPYTCDVCSMSFESTYSLKRHEARLSNTGDYMCDLCGRRFPGIEWLKEHQKRHAVNPKRQRYSCPDCDETFQSVLSQYQHIVHQHGKQKWFGKIPNQRRQGAAKTAQKAQNGKGKQGPTTGNTVNKESPATEKCANEDNASLIEEHLRNSGAELLSRMCPTCSTKYPTFNSSQFHFEGSPDRCIGCKLTFTTEAKLKQYPSKPHVRVKPINMEDAPCLTTKEDPDVVPVVLDKESETAEQLGRQSNTVKSAIHVSYKNFCPIVKYESDISSEKSNDEPPSDIGKLKVRDFATMI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -