Nmel007478.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nomia melanderi
Gene Symbol
-
Assembly
GCA_003710045.1
Location
NW:262693-268047[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.6e-05 0.00099 18.5 0.7 1 23 146 168 146 168 0.95
2 15 0.00056 0.034 13.7 1.0 3 23 176 196 175 196 0.99
3 15 0.00023 0.014 14.9 0.0 1 23 319 341 319 341 0.98
4 15 0.15 9.1 6.0 0.2 1 23 347 370 347 370 0.97
5 15 2e-05 0.0012 18.3 2.0 1 23 396 418 396 418 0.98
6 15 1.1 68 3.3 0.0 1 23 433 455 433 455 0.86
7 15 0.34 21 4.9 0.4 2 23 465 487 465 487 0.94
8 15 0.0025 0.15 11.6 3.0 2 19 495 512 495 516 0.95
9 15 0.00013 0.0076 15.7 3.5 3 23 524 544 522 544 0.97
10 15 0.0049 0.3 10.7 0.1 2 23 550 571 549 571 0.96
11 15 5.3e-06 0.00032 20.1 0.4 1 23 580 602 580 602 0.98
12 15 0.0023 0.14 11.8 0.2 3 23 610 630 608 630 0.97
13 15 0.002 0.12 11.9 0.2 3 23 638 658 636 659 0.94
14 15 0.69 42 4.0 0.0 1 23 673 695 673 695 0.92
15 15 0.0016 0.097 12.3 0.0 1 20 1072 1091 1072 1094 0.94

Sequence Information

Coding Sequence
atggaTGTACCTGGAGATTTAACGTTGCAATGGGTGGAGGAGGTGGGAAATGTTATTCACGAGGAAGTAATATGTGGTTTAGAAGCAGAGTTAGTTGCTCCAGAAGAAGGAGTAATAGGAGCTTGCGAGGAAGTTACAGTTGAAGAGACAGTCGAATCTGGCCCTAATATTACTTCTACAACAGAGTCGGAAATATTAATGGTTCCGCAATCTAGTGATATGGAATCTATTTATATAGTGCCGCAGGATCAAGGACATGATTATCTAAATATTCAGGTTACAGAAGAAGTGATAGCAGATAATTGGGATCGATCTGGTCACGAAGATGGggTTGAGATACCAGATTCTAAAGTGTCTCATGATAATTTACTTGAATATGATGATATGGAAATACCATTACCTATTGACCAAGATTCGTACACAAATAGTAGACCCTATCCATGCGACTTCTGTAGCAGAAGGTTCAGGAAAAAAGCAAATTTAATGAATCATATGGTAGCACATCAGACAGATCGCCCTCACGGTTGCAATTTGTGTGGAGCACGTTATGCTCGAAAGTGTGATCTTATGAATCATTTGAAGATTCATGCGTATGCGCCATCTCGAGATGGTTTGGAGGATGATTTGAATGACGACGATCCACTGGCACCAGAGGCTGAAGAGTCTACCAAAGGTAGACGTAAGAAAGTTCAATCCAGTGCGCCAAGGAAACGTAAAAACTACTCTACACTCCCAAAACGTACTGTTGAGgataataaaatggaaatgggCAAGTACGTCAATGAATCGTATGATTATGTTGACGAAGATACACGTTTGTTAGAGGAAATGACTAGTAGAAATTCTACATGCAGTGGTAACTATGCGTCAAGCTCGAAATGGAATGATCAGATATCGTCTGTCTCTACTGAACCTCAAGCACCAAGGTGGCCTATAACTGATCCAACAAAACCATACGTGTGTCAGTTCTGTGGTGTTGGTTTTGCGCGAGAAAAGGCACTTGCATCTCATGCGCGCATACATGGTGGTGATAGTCCATTTGAATGTACATCATGCGGTGACATGTTTTGGGATGTTAATAGTTTAAGGGAACACGTTCGTACTAAACACGGCGGCACTGTACAGTCTGATACCGAAGAATATGACAATGACGCTACATATACGGGCGATGAAAGATTTGGAGAGTTTTATTGCAATACTTGTGGTGTTCCTTTTCATCGTTTGGATTTACTTAAACGTCACCAAAAGATTCATATCAAGCAAGAGGATGATACAATGGAAGGTTCAAGTCAACACCATGTTTGCAATGTTTGCGGAGAGTGGTTTGAAGAGGCTTTAGCATTGCTAGCACATGCTGAACTTCATGCTAGTTCTTTCAGATCACCTAGTCGTCGGTGCTTATTGTGCGGTGAAAGATGTCGCGATGATGCAGAAGTTGCAGAACATGTCCGTCAAAATCATGCTGAAGATGCTCCACCAAATACTTGCACTCTTTGTGGGAAAACATGTAAAGataaacgcagtttattaaaacattcatgGGTTCATAATGTCGATAAAACTTTCGGATGTACAAAATGTGGAAAACGTTTTCACAGTAAAGCTAGATTACGAAGGCACATGGTGTCGCATCGTAATAAAATGGTAGTTTGCGATGAATGCGGAGAGGAATTCCCTGACGGTAGAGCTTTGGTCAGCCATCGTCATTCACACAATAAAGATTTAGGCGGCCGTTCTTTTCCGTGCAGAGAATGTGGAAAAACATTCGGAAGTCGCAGTTCGCAACAGATTCATATACGTATCCACACTGGAGAAAGGCCGTACGGATGTAGATTTTGTTGGAAAGCATTTGCCGATGGTGGAACTTTAAGGAAACACGAACGCATTCACACAGGCGAAAAACCATATGGATGCGCGATTTGTCCTCGCGCTTTCAATCAAAGAGTTGTTCTCAGAGAACATGTTCGTGCTCATCATTCAGGTCCCGATCCAAAATGTGTAGGTAGCGTTACTCCATATTTGTGTAAGGTATGCGGCGATGCATACGGAACATCCGAAGAGATAGTTGCTCACATTGTGCAACACTGTGATGATAATACCGCGTTAAGACGACAGCCGCAAACTGGACCTCGTAAATATAAAAGGAGACGTAAGCTTAAGCCTCATGAAACTAATACAATGTTACGTATAAGCGAGCAGTACGATATGATGGAAGCAGGTTCCGATTCAGATGATAATACCAAGAGAAAACTTGGAAGGAAGAATAAGCAGCATCGGTCGAATGTCGAAGAAGGATATCAAAATGTTCTTAAAAGTTTTGAGAGctctttacaaaatataaattcaattgttagtaattcgaaattaaacCCAGGGAAATCCAAGTTATCTAAGAAGAAGCTTAGAaaagaggagaagaagaatGAAGCTCAAACTTCGTGCCAACCTGGGAGACCAAAAATGATTCATACACAGAAAACAAGAGTGCCTGTAGAAATTGGTAGTGACGGGGTTAAGAAGGGGCAAAAAACCAAAACTATGGTGACAAGGACTCCTAAAGTAATGCCAAATGAACATAAATTAGGAATTTTTCCAGGTGGAGAAAGAAATAGACCAAGAACAAAAAACGTTAGCTATCACATCGAAGGGAAGCTTCAGCCACCGCCAGCAACATTCCCAAAGCCAAAGGAAGAAGTTTCAAAAGTTTCAACGCCAACGCATCAGCCGTTGCCATTAGTTAACATAAAGCTGGAACCTAACACACCAAAAATACCTAGTAACAACCACAGAAATAACAATGGTAATATCCTTGCCGTTAACAACGAAAAGATAGAACCGACATCTAGAAAAAGAACGGGTGTTctgaaaaaaattaagaagCAAAAACATGGAATCAAGCAAGAACCGATGGACATCGATCAAGAggaaatacagaataataataacacagaGAACACAGATTCCGCAAGATTAATGGAACATGCGGTGGATGGAAGTAATCTGGAGATTGCATTTGAAGCGAGTGTCACCACCGAGGAAGATAACAAGTACCTTCCCGATGTagggaaaattaataataccgAAGATGTTGGAGCTGGAAATGTAAAACTTAGTGTGAAAGTTGAATCCACACCTCAGCGAATGTTGGCTGTTCATAGTGTTATAGCGCCTGTGGATGATATTCCAGAAACTATAATACCGGATGCTGTAGAATATACATGTGAGATGTGTTCTGCAGTATTTTCCAGCCGTGCAGAGTTGTTGGTGCATGTTCCGATAcacatttga
Protein Sequence
MDVPGDLTLQWVEEVGNVIHEEVICGLEAELVAPEEGVIGACEEVTVEETVESGPNITSTTESEILMVPQSSDMESIYIVPQDQGHDYLNIQVTEEVIADNWDRSGHEDGVEIPDSKVSHDNLLEYDDMEIPLPIDQDSYTNSRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYARKCDLMNHLKIHAYAPSRDGLEDDLNDDDPLAPEAEESTKGRRKKVQSSAPRKRKNYSTLPKRTVEDNKMEMGKYVNESYDYVDEDTRLLEEMTSRNSTCSGNYASSSKWNDQISSVSTEPQAPRWPITDPTKPYVCQFCGVGFAREKALASHARIHGGDSPFECTSCGDMFWDVNSLREHVRTKHGGTVQSDTEEYDNDATYTGDERFGEFYCNTCGVPFHRLDLLKRHQKIHIKQEDDTMEGSSQHHVCNVCGEWFEEALALLAHAELHASSFRSPSRRCLLCGERCRDDAEVAEHVRQNHAEDAPPNTCTLCGKTCKDKRSLLKHSWVHNVDKTFGCTKCGKRFHSKARLRRHMVSHRNKMVVCDECGEEFPDGRALVSHRHSHNKDLGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCVGSVTPYLCKVCGDAYGTSEEIVAHIVQHCDDNTALRRQPQTGPRKYKRRRKLKPHETNTMLRISEQYDMMEAGSDSDDNTKRKLGRKNKQHRSNVEEGYQNVLKSFESSLQNINSIVSNSKLNPGKSKLSKKKLRKEEKKNEAQTSCQPGRPKMIHTQKTRVPVEIGSDGVKKGQKTKTMVTRTPKVMPNEHKLGIFPGGERNRPRTKNVSYHIEGKLQPPPATFPKPKEEVSKVSTPTHQPLPLVNIKLEPNTPKIPSNNHRNNNGNILAVNNEKIEPTSRKRTGVLKKIKKQKHGIKQEPMDIDQEEIQNNNNTENTDSARLMEHAVDGSNLEIAFEASVTTEEDNKYLPDVGKINNTEDVGAGNVKLSVKVESTPQRMLAVHSVIAPVDDIPETIIPDAVEYTCEMCSAVFSSRAELLVHVPIHI