Nmel002156.1
Basic Information
- Insect
- Nomia melanderi
- Gene Symbol
- -
- Assembly
- GCA_003710045.1
- Location
- NW:74515-94460[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.039 2.3 7.9 2.4 1 23 379 401 379 401 0.97 2 18 0.00053 0.032 13.7 0.9 2 23 436 457 435 457 0.98 3 18 0.0017 0.11 12.1 1.4 1 23 579 601 579 601 0.96 4 18 0.0018 0.11 12.1 0.4 2 23 605 626 604 626 0.96 5 18 9e-05 0.0055 16.2 0.6 2 23 708 729 707 729 0.96 6 18 0.00015 0.0092 15.5 0.5 1 21 735 755 735 759 0.92 7 18 0.00095 0.057 13.0 3.4 2 23 838 859 837 859 0.95 8 18 0.00016 0.0094 15.4 4.2 1 23 916 938 916 938 0.96 9 18 0.0002 0.012 15.1 0.7 1 20 943 962 943 964 0.94 10 18 0.029 1.8 8.3 0.5 2 23 975 996 975 996 0.97 11 18 2e-05 0.0012 18.2 0.6 2 23 1035 1056 1034 1056 0.97 12 18 1.8e-05 0.0011 18.4 1.6 1 23 1061 1083 1061 1083 0.95 13 18 0.0001 0.0062 16.0 2.9 1 23 1089 1111 1089 1111 0.98 14 18 3.2e-06 0.0002 20.7 0.4 1 23 1127 1149 1127 1149 0.95 15 18 2.6e-07 1.6e-05 24.2 0.6 1 23 1155 1177 1155 1177 0.99 16 18 2.8e-05 0.0017 17.8 0.2 1 23 1183 1205 1183 1205 0.97 17 18 0.00011 0.0064 16.0 4.1 1 23 1211 1233 1211 1233 0.96 18 18 0.0074 0.45 10.1 0.4 1 20 1239 1258 1239 1260 0.89
Sequence Information
- Coding Sequence
- ATGGACGCCGTAGAGATAAATACGACTGATTCAGCGCAAAATGAGGAAGATAGCATTGTATCCGCGGTGGAGATATGTCGCGTTTGTCTCCTTGGTAATCTCGTGATGCGAGATTTGTTTCTAGAAAACGAGGTTTCTTCTCTGTCAACAAAAGCGATGAGCTTTGCAAACGTTAAGGTGGAACAAGCCGATACGGTTCTAAGGGAAAGATTCGTTACCATGAATATGAAAGAAGAATTGTTCTTCAACGAGGTCGAAGTACATCTAGAGGCGGGAGATAGAAGCGAAGACATAGAGCAGATGCATATAGAAAATCACTATGAAAGTACCGTAGAAACATTGGATACGATGTCCGGAGAAGAAAAGTCTTCCCTTTTGAAGGATCAATTGGCTTTGTTGCAAGTAGAAAAACTAGCAGAGCAGGAGCAGGCGATAACCGAACAGCACGGTGGTTCGGTAACGGATGAAGTAATCGCGCCGGATCAAATGCTAGACGAATGTTCGAACCGAGAGGAAGATggggaggaagaggaagagggagaagaagaagaggaagaggaggaggaagaagaggaagacgaagaggaagacgaggaggaagaagagggaGAGGGCGAgggagaagaagaggaagacgaagaagacgaagagggTGGCAAAGCCGTCAACGATATAGATAACGAAAAGATTTTGAAACACGAAACCCCCGAAAATTGTATCGAGAGTATTTCGACGGTAGAGCACGACTATATTTTGCAACAAGAATGTATATTGGCAAATGACGGTcaacgaaaagaagaagaacgcGAAGAACAGCATCAGTTGATGTCCGAAGAATCGTTTTCGCGCGAAGATTGTGTTCAATATGTAAATTTGTTGGTGAAAGCGGCTGACGTGACCCATCGAGGGAACGAAGATGAAAGTGAAATAGGGAAACGAGAGAGTCTGAAAGCGGATATCAAGGTAGAGGAAGATTCCAAGTGTCAAAGCGACACGAGGAGAAGCAAACGCAAGCTGATTCGACGGAATACCGATCCGATACGAGATTCCGACGAggagaattattttgaaaatctcAATTTGAGTTCGCGGCTCAAGAAAGCTGAAGACTCGGATAAAACGGAAAAAATCTTTTTCATGTGCTACCTTTGCGACAAAGAATTTCTCTCGAAGAACGTTTTACGGGAGCATATGCATTCTCACGAGGAAGTGAGAAAAGCCTTGTCCTTGAAGAAAACTGTCGAGAAATCCGAGAAAGATACTTGCAGTCCCACAAAGTTGCCTCCATCCGGTAAAAGATCGAATAAATGTCCTTACTGCGGTAAACAATACATATACATCATTTCGTTCAGTAAACACTTGAAGAAgcacgagaaagaaaaagaagaagccAAGGAGGAACCGATGCCGttggaaatttcgtttcacgAAGACGAGCATAGTTTGGATCTCGAGGATTACGCGGACAAAGATCATTCGAATGCCGAGTACCGAAAAAGAGTCAGAAGAAGAGAAGGCGCGGTTACGGCAAAATCGGAGAAAGGGGAAGGAACGGGAGAAGAAATGACAGACGGGGAGGCCGAACAGGATGGAGAGGGGCTAGGGGGGAACAGGAcaggggaaagagagaaaggaaaagagaaagaatcgAGCGGCGGCAGCGATAAAGAacgaaatggaaataatttgaatgaaaccGACGAACGAATGAAACGCGAAGCGCGCACCGAATCGTTCGCCTGCGACAAGTGTCTGGAAGAATTCTCTACTAGACGCGGTTTACGAAAACACACGTTTTCCCACAGCACTCTCAGATGTAGCGTATGCGAAGAGGAGTTTGATTCGTTGGAGAAGCTGAGAAACCATCGGGCGAAACATGTCGTCGAAGGTGTACTGTCCGAACAAGACTTGGAAACAGGCAGTGTGTTTTCAGTCGACAGAGACGTGGACGGTTACGATGTCGAGGATAAACACAGAGAGGCAGAAGGAATCGGCGATGCGGAAAGGCGCAaggagaaggaggaagaaCGAGGACAAAGGGAACGTCAGACACAATTGTCAGTGGTAGAAAATGGATCGAAGAAGATGAGaaacatGGAGACGCATTCGATGGTTGAGATCACTTGTAAGATATGTTATCAGCGATTCGCAAGAATGGATTTATTGCAGAAGCATATGGAGCAGCACGAACGAATTAAAAACTACAAGTGTACAGAGTGCAATAAAACATTCGGCAACGAACTCACTTTACGAAATCATCTCATAGCTACGAATCACAAGACGTTCATTCACGGACAAGAGTACGACCCTAACAAACGGATCAAACGAGTAGCCGCGAAGGCTGCGCAGAAAATTATCGATAAGATCAAGACGGAAGATGGTTTGGAAGATTACGAGGACGAGGAAGAACAGGACGAGAAAGTGATCGAGCGGAATCCCACGGATGGAAGTTACGGGCGAAACAAGCGAGATATCTCTTCTCAGAAGAAACACAATTGCAAGAAGGAGTTGGAATGCGCGAGTTGCAATAAAAAGTGCAGCTCGAAACAGTCATTGACGAAACACATGGAGCAGCACGTGAAAGACGAGAAAACAAGCAAGTCGGAGAAGCACAGGCAGCTCGGGGAGAAGAGGGAACGGCAGAGGAGTTGCGCGGCGAACGAAGGAATCGAGTCGAGCGAAGGCAATAAAGACGACGATTACGATTCCGATTTTGAAAGCGGTCTGGATTGGCCGATGGACAATCACGAGTGTGCAAAGTGCAAGAAACGGTATAGCACGAAAAAGTCGCTGCTGCGGCATCAGCTGTTGCACGAGGAACCGAATTTCGAGTGCGACATTTGCAACGTGAAATTCTATCGTAAGGACAAACTGAAAGCTCACTACGACAAATGTTCTGAGAAGAATCCTGACCAGGTGAGAAAGTGTAACATCTGCGGGGACAGTTTCGAGAACAACGAAATACTGCGGGAGCACAGGTCCAAACATGTGACCGAAGGGATTCTCACGGAAGAGGATTTGAGGGACATCGAACCGAGGCCGGAAGAGAAGAAGCCGGGAGAGAAAATCGGCAGGAAGAGAAGGACCGATATAGTCGGCTTAGAGTGTACCGAGTGCAACAAACAGTACACTTCCAGGAAAGGACTGTTGCGTCACATTCAGGTTCACGAGGGGAAGAAGTACCTTTGCGACATATGTCCGAAGAAATTCTACAGAAGGGAACATTTGAAGATACACGTGGCTAAGCACAACATGATTAAGCCGTACAAGTGTACGCGCTGCACGAAACGTTTCATCAAGGAAGAACAATTGACCAATCATTTGTCGAAGCATGACCGGACCTTTAAGAAGAACAAAGAAACCGACAGTTCCAAGAGATTCCTCTGCGAGATTTGCTCGAAAAGCTTCACTCAGTCGACTACGTTGATTGCCCACCTTCGGGCTCACAACGGCATTAAACCGTACGTGTGCGAGGTTTGCTCCCGACCCTTCACGACCAACGCTTACCTAAAAATGCACATGAGAACGCATACCCAAGAGCGGCCGTACATTTGTCAATACTGTTCGCGTGCATTCGCCAGAGCCGACACGCTTGCCAATCACTTGACATCGCACACCGGCGAGGCAAAGTATCACTGCAAGTATTGTCCGAAGAATTTCCGTCGTTTGAAATCCCTCAAGGAGCACGTGTTCATTCACACCGGACAGAGACCGTACGCTTGCCCAACCTGTGATCGCCGGTTCAATAATAATGGAAGTCGATATGCCCATAGCAAGAGGtgcaaacaaaattttgttcagAATCAAAACCGTGGCCAGACGTTGACGCAAGTTCAGTCCGCTCAGAATCAGCAGAGGATATTGCATCAGCAGACGGCTCTTGGACAGActcaattattgaaaacgcAGAACATTAAAACTATTACAATTACTAGACAACCGGAACCAGTTGCTGCTCAACAAGTCACGCAGCACCAAGAAATAATAATGCCCCTAATCTTCCCTCTAACCGTAACGGTAGCCGATATCAGCGAAGAAGTTATATTGCCGGAGGGAACCAAGTTGTTTACGACCACTTAA
- Protein Sequence
- MDAVEINTTDSAQNEEDSIVSAVEICRVCLLGNLVMRDLFLENEVSSLSTKAMSFANVKVEQADTVLRERFVTMNMKEELFFNEVEVHLEAGDRSEDIEQMHIENHYESTVETLDTMSGEEKSSLLKDQLALLQVEKLAEQEQAITEQHGGSVTDEVIAPDQMLDECSNREEDGEEEEEGEEEEEEEEEEEEDEEEDEEEEEGEGEGEEEEDEEDEEGGKAVNDIDNEKILKHETPENCIESISTVEHDYILQQECILANDGQRKEEEREEQHQLMSEESFSREDCVQYVNLLVKAADVTHRGNEDESEIGKRESLKADIKVEEDSKCQSDTRRSKRKLIRRNTDPIRDSDEENYFENLNLSSRLKKAEDSDKTEKIFFMCYLCDKEFLSKNVLREHMHSHEEVRKALSLKKTVEKSEKDTCSPTKLPPSGKRSNKCPYCGKQYIYIISFSKHLKKHEKEKEEAKEEPMPLEISFHEDEHSLDLEDYADKDHSNAEYRKRVRRREGAVTAKSEKGEGTGEEMTDGEAEQDGEGLGGNRTGEREKGKEKESSGGSDKERNGNNLNETDERMKREARTESFACDKCLEEFSTRRGLRKHTFSHSTLRCSVCEEEFDSLEKLRNHRAKHVVEGVLSEQDLETGSVFSVDRDVDGYDVEDKHREAEGIGDAERRKEKEEERGQRERQTQLSVVENGSKKMRNMETHSMVEITCKICYQRFARMDLLQKHMEQHERIKNYKCTECNKTFGNELTLRNHLIATNHKTFIHGQEYDPNKRIKRVAAKAAQKIIDKIKTEDGLEDYEDEEEQDEKVIERNPTDGSYGRNKRDISSQKKHNCKKELECASCNKKCSSKQSLTKHMEQHVKDEKTSKSEKHRQLGEKRERQRSCAANEGIESSEGNKDDDYDSDFESGLDWPMDNHECAKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNFVQNQNRGQTLTQVQSAQNQQRILHQQTALGQTQLLKTQNIKTITITRQPEPVAAQQVTQHQEIIMPLIFPLTVTVADISEEVILPEGTKLFTTT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -