Basic Information

Insect: Nomia melanderi
Gene Symbol: ZNF236
Assembly: GCA_003710045.1
Location: NW:981858-990447[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00014 0.0083 15.6 0.9 2 23 188 209 187 209 0.96

2 26 7.5e-05 0.0045 16.4 1.1 1 23 215 237 215 237 0.98

3 26 2.2e-06 0.00014 21.2 0.4 2 23 243 264 243 264 0.97

4 26 0.0023 0.14 11.8 0.2 3 23 272 292 270 292 0.96

5 26 6.4e-05 0.0039 16.6 1.1 2 23 303 324 303 324 0.98

6 26 5.3e-07 3.2e-05 23.2 1.1 1 23 345 367 345 367 0.99

7 26 2e-06 0.00012 21.4 0.7 1 20 373 392 373 395 0.96

8 26 1.3e-05 0.00076 18.9 0.4 1 23 401 424 401 424 0.95

9 26 0.0019 0.11 12.0 2.2 3 23 435 456 433 456 0.97

10 26 1.2e-06 7.4e-05 22.1 2.9 1 23 583 605 583 605 0.98

11 26 0.00023 0.014 14.9 4.1 1 23 611 633 611 633 0.99

12 26 0.044 2.7 7.7 2.4 1 23 639 661 639 661 0.98

13 26 0.0035 0.21 11.2 6.7 1 23 749 771 749 771 0.98

14 26 3.2e-05 0.0019 17.6 4.9 1 23 777 799 777 799 0.99

15 26 0.00015 0.0091 15.5 0.8 3 23 807 827 805 827 0.97

16 26 0.00029 0.018 14.6 7.6 1 23 833 855 833 855 0.98

17 26 0.13 7.8 6.2 1.9 2 23 1263 1284 1262 1284 0.96

18 26 0.00025 0.015 14.8 1.8 1 23 1290 1312 1290 1312 0.99

19 26 0.00051 0.031 13.8 1.4 2 23 1319 1340 1318 1340 0.96

20 26 2.3e-08 1.4e-06 27.5 1.4 2 23 1419 1440 1418 1440 0.98

21 26 0.0012 0.074 12.6 6.2 1 23 1446 1468 1446 1468 0.99

22 26 0.00018 0.011 15.3 1.9 1 23 1474 1496 1474 1496 0.98

23 26 0.0002 0.012 15.1 2.6 1 23 1502 1524 1502 1524 0.98

24 26 4e-05 0.0024 17.3 2.1 2 23 1752 1773 1751 1773 0.97

25 26 2.2e-05 0.0014 18.1 3.6 1 23 1779 1801 1779 1801 0.98

26 26 1.2e-07 7.1e-06 25.3 0.7 1 23 1807 1830 1807 1830 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00014	0.0083	15.6	0.9	2	23	188	209	187	209	0.96
2	26	7.5e-05	0.0045	16.4	1.1	1	23	215	237	215	237	0.98
3	26	2.2e-06	0.00014	21.2	0.4	2	23	243	264	243	264	0.97
4	26	0.0023	0.14	11.8	0.2	3	23	272	292	270	292	0.96
5	26	6.4e-05	0.0039	16.6	1.1	2	23	303	324	303	324	0.98
6	26	5.3e-07	3.2e-05	23.2	1.1	1	23	345	367	345	367	0.99
7	26	2e-06	0.00012	21.4	0.7	1	20	373	392	373	395	0.96
8	26	1.3e-05	0.00076	18.9	0.4	1	23	401	424	401	424	0.95
9	26	0.0019	0.11	12.0	2.2	3	23	435	456	433	456	0.97
10	26	1.2e-06	7.4e-05	22.1	2.9	1	23	583	605	583	605	0.98
11	26	0.00023	0.014	14.9	4.1	1	23	611	633	611	633	0.99
12	26	0.044	2.7	7.7	2.4	1	23	639	661	639	661	0.98
13	26	0.0035	0.21	11.2	6.7	1	23	749	771	749	771	0.98
14	26	3.2e-05	0.0019	17.6	4.9	1	23	777	799	777	799	0.99
15	26	0.00015	0.0091	15.5	0.8	3	23	807	827	805	827	0.97
16	26	0.00029	0.018	14.6	7.6	1	23	833	855	833	855	0.98
17	26	0.13	7.8	6.2	1.9	2	23	1263	1284	1262	1284	0.96
18	26	0.00025	0.015	14.8	1.8	1	23	1290	1312	1290	1312	0.99
19	26	0.00051	0.031	13.8	1.4	2	23	1319	1340	1318	1340	0.96
20	26	2.3e-08	1.4e-06	27.5	1.4	2	23	1419	1440	1418	1440	0.98
21	26	0.0012	0.074	12.6	6.2	1	23	1446	1468	1446	1468	0.99
22	26	0.00018	0.011	15.3	1.9	1	23	1474	1496	1474	1496	0.98
23	26	0.0002	0.012	15.1	2.6	1	23	1502	1524	1502	1524	0.98
24	26	4e-05	0.0024	17.3	2.1	2	23	1752	1773	1751	1773	0.97
25	26	2.2e-05	0.0014	18.1	3.6	1	23	1779	1801	1779	1801	0.98
26	26	1.2e-07	7.1e-06	25.3	0.7	1	23	1807	1830	1807	1830	0.97

Sequence Information

Coding Sequence: ATGTTGACACGACACGCTATAATCGCAGAATCTAATCAAATCGCAGCCGTGCCAATAAATGTTGTCCCCACCGAGGACGGCCGAACGCTGTTAGCGGTGACAGAAGACAAGGAGGGTTTGTTGGAAATTGTCTCAAGCCCGGTTACGCTTGTCGACCACAGTGGGACAGCCGCATCATTGATGGATGTGAAGAGTCTGAATGGTTGCTTGATATTACATCCGGTATGCCTGTATTCGATCATTATGTTTCTCCTTTGCGAAAGGGANNNNNNNNNNNNNNNNNNNNNNNNNNNcctgtttcaaataaatttagaagATGTTGAGAGTTCAGAGCTCGAAGAGTCTAAGCAAAGTCTTCAAATCGAGCCTGATGTTCATCAAAGAACCAAAACCAGATTAAGTCTGGATACGATACATCATTTCCTTGACGATGAGTCTTTGCCAAGAGAAAAAAGCAATGGAATCCATAAGGAAAAGCCGACAGCTGTGGCTCCTAAAATAAGCAGCCCTGGAAGGCCCAAGAAGAATGCGTCAATAtcattaaaaGCTAAAGAAAGTTTAAGATGTGAAATATGTCAGCAAGAATTTACGAAGCAAGCACTGTATAAGAAACACATGGAAAATCATGCACAAGAGAAACCGCATCGATGTCCAAAATGTTCAGCATCTTTCAATGTACCGACTAACTTTACGCTTCATATGGCAACTCATAATACTGGTGACCCAAAGTGTCCTGAATGTGGTAAAAAGTTTGCAAGGATGGCCAGCTTGAAGTCTCATATGCTGTTACacgagaaagaggaaaacttaTTCTGTACAGAATGTGAAGACGTTTTCTCAACTAAAGCTCAGTTAGATGCACATCAGAAGCTTCATGGAGAAAGGTGGACAACTGAAGAGGCAAGGAAATGTAAACTCTGTAATAAACAGTTTCGGCAGCCTGCACTGTATCGACTTCACATTCGCGAGCATTATCGGTTGCAGACAAAGGTAGTAAAGCAGACAAAACGGGGAGCAAAGCATAAAACGGTGTATAAATGTACAATATGTTTAAAGTCCTTCCAAAAACCGAGCCAATTAATGCGCCACATTCGAGTGCACACCGGTGAAAAGCCTTTTAAGTGCACAGTGTGCGACCGTGCCTTCACACAAAAGAGTTCTTTACAAATTCATATGTGGCAACACAATGGTATTCGACCACACGCTTGTGAGCTTTGTAACGCCAGATTTAGTCAAAAAGGTAATTTAAATGCTCATATAATGAGAGTTCATAATGTGCCAGAAGGAGAGCCTATATACGGATGCAATTATTGCTCATGTGTCTTTAAGAAGCTTGGTAGCTTGAACGGCCATATGAAACGCATGCACGCGGAAGTGAACGAGGACAGTGTCACGGTAAAAAATTACGAATCGACGGACACCATGGAATCAGATATTCGTGCCACCGTAGACAGTGTCATAACGCAGCTGGCCTCTCTAGAATCGAACACAGACGAGATTCGAAAACCGGAAAACTTTGTAGGGAATACGTTGTTGTCAAATGTCCCAACGAAGAAAGACATTCTGCAGCAAGCTCTGAGAAACAGTGGGCTTCCTAGTAAAAACAAAACTGTTTGCGAAGGTCCGTCGGAAACGAAAAAGTTGGAAGCGCGCACAAATTTCGTTACCTTGTTGGACCGAGCACCAGACAGCGGCACCAGaaagtacttaacaataaaacaacgGTGCGTAGGAAACGTAAGATGGTATTCCTGTACATTCTGCCACAAAGAGTTCAAGAAACCGTCAGATCTGATTCGCCATTTGCGAGTGCACACGCAAGAGAAACCATTCAAGTGTACGCACTGTTATCGTTCCTTCGCTTTGAAGTCCACCATGACAGCACACGAACGTACCCATACCAACATTACAAAGTACTCCTGTGGTTCTTGCGATGAGACATTCACCTGTCATGGAAGCTTGGTCGCTCATACAAGGTTACACGAGAACTCCAGCGAATGTTTTGACATATCAGCTGGCAACGATAACGCTGACATTGACACAGCAACCAACATAGGCACTCGCAACGACCAACTGAAAGTCAACGGGAAAAGTAAGAAGGTGCCCTCGAAATCAGAGAGCTTAGCGTCGCAAGTGGTGTTGCAGGAGCCGTTGGTGATCAGTGATTCTGGAAACAAAATATGCGTCGTCCAGATACCTTCCAAGAAGCGAGTGTACGACGCGACCGTTGACCCAGCTAGACCACACAAATGTTGGGTGTGTCAAGCGGCGTTTAGGAAAATCAGTCACTTGAAGCAACACCATCGTCGACACACTGGGGAACGTCCGTACAGGTGTACCAAGTGCGACAGGAGATTTACGTCGAACAGTGTTCTGAAGTCGCATTTGCACACGCACGAGGATTCCAGGCCGTACGGGTGTTCCATTTGCACCGCGAAATTTTCTACTCAGAGCAGCATGAAGAGACACTTGGTTACTCACAGTAACAAAAGGCCATTCATGTGTCCATACTGTCACAAGACGTTCAAGACTTACGTGAACTGCCGTAAACACATGAAAATACATAAGCATGAATTGGCAGAACGGCAACTGGAGcaacagaaattaatatcgCAAGTACAAGCAACGAACGACTTGAACTCGAAAGAAAACTGTGGACAAGGAACAAGCACCGAACTGTCCTGTTGCGCTGCATCCATTTTTTCTCCTAACGCCGATGACGCCGCTCTCAGCGTGGCTACCGATGAAACTGGCGCTGGTAATATCGTCGCAGCATCTTCCACGTTCACCGACAATCTTGCACTCTCCCGCCTTGATCCGGTGGAAATGTCTTTTCAAGAACGAATGGCGTCAAACTACTCGCAGACTTTCTCGAACCAGCTTCAAACCATAaccgaggagaaagagaaaatgaGACCACTGTTGTCGACGAATTGCTCTTCGACGACTATCAACCAAAGTGTGACAGAAATAACGGTAACGAATCTAGAAAATTCACAAATGCTGCATATTGATGAAAGTGGCTCTGTCACGTTGCCAGTGTACTCAACCGATCAAGCTCTCACACCGGAGAGCATACAAGAAATAGAAGACACACTGAACCAGCAGCTCTTCAACATTGGAATGAACCTCAATTTGGGAAGCGACCATTCGAAGCAGACGTGCAGCGCCAGTGAGCTGCAGAATGTGAAGATACAGCACCAACAACCCGCGCTGAACGTTATTTACACGAGCAACAATAACtccagcaacagcaacaacgcAGAGCAGTGCGGTGAACAAGTGTTCGCGTCGCAGCTGGATTCATTCGAGATGGATCACATCACTTTGCAACCGGAAACTGAAATAGCACTGGACAATATTGGCCTGGACACAAACAGTTCAACGAGCATGGCAAGCATACTGCCACAAAATGTGAAAGAGGAGCGTCAGCTCGCCGTTTCTGTCGCGTCGCCAGAGAACTTGAGCAGCAGTCGCCAAGCAAGTAGGTACATGCAGACTGTAGTGTTAATTTCCGAGGAGAATCTTAGAGAAAAAGGAATCGGAGCGAGCTACAACGAACTGGAGGTGCACGAGCCAGAGAAGAACAGCGACCGGAGACAGTGCGTCGCTAATGATCCAACCTTGTTAACAGAAGAGTTTCGACGAAGAACGAAGGTGTCGAAGCCACAGAtatcgttgtcgtcgtcgtcctcctcGTCCTCGACGTCGTCGTCACCTTTGATCCTGAATAATCAACGCGTCGAAATCGATGCAGGCCAGTCGTGTCGAGAGGAATCCTTGCTACAGTGTCATATGTGTAGCCAACAAGGATTCACAGCGACCAAATTGAAGGAACACTTGAAAGTCCACCGTGGGAAAAAGGAGTACCAGTGCACGGAGTGTTCTTCAAGATTCTATACAAATGGAGGATTGAACAGACATTCGAAGACACATACGAATAAACAACACTGGAAGTGTTCGCTGTGTGACAAGTATTTTGATAATAGAATGCAACTGCGGTCGCACAACAAAGTTCATGAGAACTTCTCGTGGAATGCTACGCCTTCGaagataaacaataataaagatattcCGACCTTGTCGGAGATACGAGTGGCGATAGTTAACGAGTCGTTGAACGATATAGTAGTGGAGGATTCTGATTCGGCTGTGTCGGAAAGAGTTCTACTGGACACGGTTGCGGAGAGGAAGGTGATGGACCGAGTTGGATGCGTAACGACGGAGAAGAAGGAACAAAAGGAGTATacgaataaatgtaaatactgtCCAAAGACGTTTCGCAAGCCAAGTGATCTAATCAGGCACATACGTACACACACAGGGGAACGGCCGTACAAATGCGACTACTGTAACAAATGTTTCGCCGTGAAGTGTACCTTAGACTCCCACACTAAAGTTCACACGGGCAAAAAGACGTTTCGCTGTCACGTGTGCAGCAGTTTGTTCGCCACGAAAGGCAGCCTGAAAGTCCACATGCGTCTACACACAGGTTCAAAACCGTTCAAATGCCCCATCTGCGACTCAAGATTCCGCACATCGGGTCACAGGAAGGTGCACTTACTGAAGCACGCGCGGGAGCACAAAGGTAACTTGAAGAGGAAACAAAAGCACCTGAAAGTCGCTGCAGTAGCAGAGGTCGCGGCTGACATTGGAAAATCCGACgcaaaagagaaagaaacttatgaagaggaggaagaagcaACAGAACAGGAACAAGATAACCATTACGAGCAGGTCCCTCAAGTAACCGAACCGGAGTACTCCCATTTGCAGGCGATCAGCGTCGAAACAACTGCCTCGTGCTTAGCAGACCAAATCACTTTTGAACCCGAGGGTTCCGTTCCGAACAACAGCTCAATCCTGTCTGTGAACGAAGGCAATCAGCTGGTTGCCAACTTGCACTTCTTCCTGGCGAACGGTTTGGTCACCATTCAGACAGAGGAATCTCTGTTGCCGCAAGCGGCGTCGGCTGCTAACGCGTTGCATCACTCGACTGTCGTCGCCGACCCCATGTGCGCATCTGTGATAAGCATCACGCCGGAGGCCAGCGGCAATCAAGACGTAACTAAGGAGACCGTCCGCATAGAGGACACGTTGAAACTGTCGTCTCCGTATCAGTTGCAATCGAGTAACTGTCTGTTGACCGACGTCGCGACTCCGACGCAAATGGAACCGTTCCCCAGGCTCGCGGTCGAGAAATGTCTACCGGCCTCAGAGAAGACGCCCGTTAAGGGAAGCTCGTCGAAGAAGGAGTGCGACGTCTGTGGGAAGACGTTCACAAAACCGTGTCAGGTGGAGAGACACAAACGGATCCACACCGGCGAGCGACCGTACAAATGCGACTTGTGCGTCAAGTCGTTCGCTCAGAAATCGACCCTGCAGATGCACCAGAAACACCACACGGGGGACCGGCCGTACCCCTGCCCCTACTGCGAGTACTCCTTCACGCAGAAGGGCAACCTCCGGACGCACATGAGTCGCGTCCACCGGCTGGACACCGTCGACTCCAGGAAAATGAAGTACAACCGTCAATCGTCGCACTGCAAGTCCCCTCAAGCCAACCTGGCCGACGCCAAAAGTCTGAACTTAGATGATATACCGTTTAtcgaatttcttaaataa
Protein Sequence: MLTRHAIIAESNQIAAVPINVVPTEDGRTLLAVTEDKEGLLEIVSSPVTLVDHSGTAASLMDVKSLNGCLILHPVCLYSIIMFLLCERXXXXXXXXXXLFQINLEDVESSELEESKQSLQIEPDVHQRTKTRLSLDTIHHFLDDESLPREKSNGIHKEKPTAVAPKISSPGRPKKNASISLKAKESLRCEICQQEFTKQALYKKHMENHAQEKPHRCPKCSASFNVPTNFTLHMATHNTGDPKCPECGKKFARMASLKSHMLLHEKEENLFCTECEDVFSTKAQLDAHQKLHGERWTTEEARKCKLCNKQFRQPALYRLHIREHYRLQTKVVKQTKRGAKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCDRAFTQKSSLQIHMWQHNGIRPHACELCNARFSQKGNLNAHIMRVHNVPEGEPIYGCNYCSCVFKKLGSLNGHMKRMHAEVNEDSVTVKNYESTDTMESDIRATVDSVITQLASLESNTDEIRKPENFVGNTLLSNVPTKKDILQQALRNSGLPSKNKTVCEGPSETKKLEARTNFVTLLDRAPDSGTRKYLTIKQRCVGNVRWYSCTFCHKEFKKPSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMTAHERTHTNITKYSCGSCDETFTCHGSLVAHTRLHENSSECFDISAGNDNADIDTATNIGTRNDQLKVNGKSKKVPSKSESLASQVVLQEPLVISDSGNKICVVQIPSKKRVYDATVDPARPHKCWVCQAAFRKISHLKQHHRRHTGERPYRCTKCDRRFTSNSVLKSHLHTHEDSRPYGCSICTAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAERQLEQQKLISQVQATNDLNSKENCGQGTSTELSCCAASIFSPNADDAALSVATDETGAGNIVAASSTFTDNLALSRLDPVEMSFQERMASNYSQTFSNQLQTITEEKEKMRPLLSTNCSSTTINQSVTEITVTNLENSQMLHIDESGSVTLPVYSTDQALTPESIQEIEDTLNQQLFNIGMNLNLGSDHSKQTCSASELQNVKIQHQQPALNVIYTSNNNSSNSNNAEQCGEQVFASQLDSFEMDHITLQPETEIALDNIGLDTNSSTSMASILPQNVKEERQLAVSVASPENLSSSRQASRYMQTVVLISEENLREKGIGASYNELEVHEPEKNSDRRQCVANDPTLLTEEFRRRTKVSKPQISLSSSSSSSSTSSSPLILNNQRVEIDAGQSCREESLLQCHMCSQQGFTATKLKEHLKVHRGKKEYQCTECSSRFYTNGGLNRHSKTHTNKQHWKCSLCDKYFDNRMQLRSHNKVHENFSWNATPSKINNNKDIPTLSEIRVAIVNESLNDIVVEDSDSAVSERVLLDTVAERKVMDRVGCVTTEKKEQKEYTNKCKYCPKTFRKPSDLIRHIRTHTGERPYKCDYCNKCFAVKCTLDSHTKVHTGKKTFRCHVCSSLFATKGSLKVHMRLHTGSKPFKCPICDSRFRTSGHRKVHLLKHAREHKGNLKRKQKHLKVAAVAEVAADIGKSDAKEKETYEEEEEATEQEQDNHYEQVPQVTEPEYSHLQAISVETTASCLADQITFEPEGSVPNNSSILSVNEGNQLVANLHFFLANGLVTIQTEESLLPQAASAANALHHSTVVADPMCASVISITPEASGNQDVTKETVRIEDTLKLSSPYQLQSSNCLLTDVATPTQMEPFPRLAVEKCLPASEKTPVKGSSSKKECDVCGKTFTKPCQVERHKRIHTGERPYKCDLCVKSFAQKSTLQMHQKHHTGDRPYPCPYCEYSFTQKGNLRTHMSRVHRLDTVDSRKMKYNRQSSHCKSPQANLADAKSLNLDDIPFIEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -