Nmel001532.1
Basic Information
- Insect
- Nomia melanderi
- Gene Symbol
- -
- Assembly
- GCA_003710045.1
- Location
- NW:1630693-1694232[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 37 0.00022 0.013 15.0 0.4 1 23 438 461 438 461 0.95 2 37 0.029 1.8 8.3 1.5 1 23 467 490 467 490 0.93 3 37 0.017 1 9.0 3.4 1 23 505 528 505 528 0.96 4 37 0.68 41 4.0 3.9 1 23 549 572 549 572 0.96 5 37 7.5e-05 0.0046 16.4 1.3 1 23 578 601 578 601 0.95 6 37 5.7e-05 0.0034 16.8 0.5 2 23 607 629 606 629 0.95 7 37 0.0036 0.22 11.1 0.2 1 23 634 657 634 657 0.95 8 37 8.1e-07 4.9e-05 22.6 2.3 1 23 663 685 663 685 0.98 9 37 3.8e-06 0.00023 20.5 0.8 1 23 691 713 691 713 0.97 10 37 0.00012 0.0072 15.8 1.5 1 23 719 741 719 741 0.97 11 37 0.0015 0.09 12.3 0.3 2 23 965 987 964 987 0.91 12 37 0.63 38 4.1 0.3 1 23 999 1022 999 1022 0.95 13 37 0.017 1 9.0 4.5 1 23 1035 1058 1035 1058 0.94 14 37 0.0011 0.064 12.8 6.9 1 23 1064 1086 1064 1087 0.95 15 37 0.012 0.7 9.5 0.4 3 23 1094 1115 1092 1115 0.95 16 37 0.0012 0.075 12.6 1.5 1 23 1120 1143 1120 1143 0.98 17 37 5.5e-07 3.4e-05 23.1 0.4 2 23 1150 1171 1149 1171 0.96 18 37 4.7e-06 0.00028 20.2 1.3 1 23 1177 1199 1177 1199 0.97 19 37 6.1e-05 0.0037 16.7 1.0 1 23 1205 1227 1205 1227 0.98 20 37 0.0052 0.32 10.6 3.4 2 23 1336 1357 1335 1357 0.97 21 37 0.00023 0.014 14.9 0.8 1 23 1359 1382 1359 1382 0.96 22 37 0.0048 0.29 10.7 0.9 1 23 1387 1410 1387 1410 0.96 23 37 0.00025 0.015 14.8 1.6 1 23 1416 1439 1416 1439 0.95 24 37 0.002 0.12 11.9 2.0 2 23 1446 1468 1445 1468 0.95 25 37 0.013 0.8 9.4 0.3 1 23 1473 1495 1473 1495 0.96 26 37 0.0012 0.071 12.7 0.5 3 23 1503 1522 1502 1522 0.98 27 37 9.6e-06 0.00058 19.2 0.1 1 23 1528 1550 1528 1550 0.97 28 37 0.00092 0.055 13.0 0.4 1 23 1556 1578 1556 1578 0.97 29 37 6.9e-05 0.0042 16.6 0.7 2 23 1655 1676 1654 1676 0.96 30 37 0.032 2 8.1 0.4 2 23 1679 1701 1678 1701 0.93 31 37 0.24 14 5.4 1.4 1 23 1706 1729 1706 1729 0.96 32 37 0.00018 0.011 15.2 3.0 1 23 1735 1758 1735 1758 0.96 33 37 9.7e-05 0.0059 16.1 0.5 3 23 1766 1787 1764 1787 0.96 34 37 0.0001 0.0062 16.0 1.3 1 23 1792 1814 1792 1814 0.97 35 37 0.75 45 3.8 0.1 2 23 1821 1841 1820 1841 0.88 36 37 3.3e-06 0.0002 20.7 0.1 1 23 1847 1869 1847 1869 0.96 37 37 0.003 0.18 11.4 0.4 1 23 1875 1897 1875 1897 0.97
Sequence Information
- Coding Sequence
- ATGTCCTCCCTCGATTATCTGGACCTGTGTCGGCTGTGTCTCGTGAAGGACCGTGCTTCGGTGCCGATTTTCGAGGGCGAGGGTGACGAACGGCAGATTTTTCTCAAGATCGCCGCCTGTCTACCGGTCAAGGTTGCAAGAGAAGACAAATTACCTAAGAAAATATGCGACGATTGTGTGTATAAAGTAGAATCATTTTATCACTTTTGGAATACTACAGCAAACGCAGAAAAGCGACTGCTACAATGCCTGGGAGAAGTTGGTGTGGACGGCGGCAAACAGGGTTATGTTTCCAATGTATTCAATCcgAATGTGATGAAACAAGAACAGAGTACAGAGAACAGGTTAGATGGCAGTGTAATGCAGCAAGTGGGCGAGCATCAGAACAATATGGGTATGGGCATGATGGACAACATGGGTCTGGGCATTCCAATGATAATGTCCAATACTAATCAACAACAACAAATAACCTCAGTTCCTATGGACACAAGTGGCAGTTCTGTACAAAATGTTCAAGCAGTGCCTGGTCCAAGTTCACAAACTACGCATAACCAAATATCACAAAATCAAACCAGCTCGACACAGCAAGAAGACGAGGAAGAGAGTAGTGAGGACGATGAGAATTCCGACGACGAGTGCGATGGGGACGAAGGCCTACCTGTAAAAGAAGAGAGCGAAGAAGATCCAAACAGTAGAACTATAGAGCCTACAACCTTTGTAAATGTATCCTTGGCGTGTGATGAAGCTGGCCCTTCAGGATTGCAACAACAAAAAATTGCAGAAATGCCAGAGATGCCAATACCACAGCCAGCAGATGGTGATCCCAAAACTGGGACGCTAAACGGGGACGGACATTTTATATACGGGAAGGAATCGATACCGATGCAACCGTGGCAAATCGTCGACGTCGAAGGTTGCCTCTACTATGCCTTCCTTCCAACGAGTCAGTCCCTGAAGCTCTCAGAGCAGGAAAAGCTCGGGCCAAAGTCAGCAGCAGAGTTACTGAAGCTAGCCATGGACGACTCCAAAGAACCCTTCATAATCCCAGCCGAGGAAGAAGTGTCGCGCGCCACGAGTTATTTCAACAGAATAAAGGTGAAATCCGAAGACGACAACTCATCCCCGAACGAGGATCATCACCACGACGTCTCTTCCTCGAACGATCATCAGAACGACGTCTCATCCTTGACCGAAGACCACCAGATCGACGCCTCCTCGTTGAACGAAGATCACCAGAACGACTCATCGCTGAACGAAGATCACCAAAACATCCCTTCGTTGAACGAGGACCACCAGACCGACGACAAAGTCTACGTCTGCGAGGAGTGCAACATATGCTTCCCAGTGGCACAAATGCTGAAGCGTCATCGGAACGCGGTGCACGATCAGGCCCAGCGATACAAGTGCAAGGTATGCTTCAAGATCTGTCGCAGCCTGGTCGCCTTCAAGATGCACGTGGCGCTGGAGCACAAAACCGAGGAGCAGGAGCTGAAAGATGAGAACAGTCTGACGTACGCGTGCAACTTCTGCAGCTACGAGAGCACCAACAAATCCACCCTCCACTCGCACATCAGCAGGAAGCACCCGGTGAAGCACATAGGCAGGAGGAAGAACAGCTACAGATACACAGCTGAGCCTGAAGAGTATTCCTGTGACGTCTGCGAATTCAAGTGCCAAAACAGGCGCAGGCTGAAGGAGCATCTCGAAAGGAAGCACGCGTCCGAGTACAAGTACGACTGCGAGTACTGCGGGAAGAAGTTCAAAGTGAAGGGCGATATGAGGCTACACGTCAGGTTCAAGCATAAGGAGGGTCCCATCGTTTGCGACGTTTGCGGTAAGACCTGCTCCAACAGCAACTCGCTGTACGTTCATCAGAAGTGGGCGCACTTCAAGCCCAAGTACGAGTGCGAGATCTGCAAGAGGCGGATGGTCACGCAGGAGAATCTCGATCAGCACATACTCCTTCAGCACGAAAGGCGCGAGAGCTTCGTATGCGAGGAGTGCGGTAAATCGTTCACGGAGAATCACCGGCTGAAGCAGCACATGATGACGCACACCGGGGACAGGCCGTACGATTGCCACATCTGCGGCAAAGCGTTCGCGCGTCGCACAGCTTATAGGCAACACTTGCTCATCCACACGGGCAAACGTCCGTACATCTGTGATATTTGCGGCAAGACGTTCACGCAGAAGCCTGGACTGATCTGTCACCGGAAGTCGCATCCCGGCGTTCCCGATCCGCGTGGTATCTTTCTCTACGACAAGGAGTCGGTGGTGATGAAGAAATGGCAGATCCTGGAGTTCGACGGGAAACCGTACTACGCGTTCGTCCCTGAAGGAGACACGCCGTTGCTGGACGAAGAGATACCGGAGCAGATCGAGGAGTTGGTGGAGGCGGAAGAGGACAAGCAGAACTTGGTGAAGGTAGAGTGCCTGTACAACGAGGAGGAGCTGCAATATCATTCATCGGAGGAGAAGCTGTACGAGGACGAGGAGCATCTGCTGAACGGTATCGCCGAGCAAAGGGACGAAGAGGACGAAGACGTGAAGCCGATCATTCTAAACGGTTCCATCGAGGGTGAGAACGATAAGATCGGTGATTTGTATCAGGTCAAGGTTCAGGGTAGCATGGTGACCATAGAGAAACTGATGTCCACCGAGGTGGACGAGAAGAAGGTAGATTACCAACAGGACACCGAGGAGCAGGACATCTACACCGAGCAAGAGCAGCTGGAGCAGTTAGAGGAGGTCGAGGACGTCGAGGAAACAGACCAATTGGACCAAATAGAACAAGTGGAGTACCTGGAGGAGGAGATCCTGGAAGCCGCGAACAATCACGCGACGCCGACGAAGACTCGAAGAAAGATCTCGAGGAGCACGGGCGGAGCGCTCAAGTGCAAAGTTTGCTCCGAGATGTTCAGCTCGGCGATCTCGTTTCGCAAGCACGTGGCCTGGACGCACAAGAAGAAGGTGTGCATACAGGAGGACGGCGCGTACATTTGCGCCGTTTGCGACTACAGGACCCTGAAGAAGAGCCTCTTCGCGGCTCACTTGGAGAGGAAGCACGAAACTTGGTCCAGGAAGCGGCCGAACAATATGCTGTTCCCCTGCGCGACATGCGGCTTCGTGTGCAGGTCGAAGCATTCGTTGCAGTCCCACTTCATCAGGAAGCACACGGACCGGTACGAGCACCAATGTAAATTCTGCTCGAAGAAGTTCAAGGTGAAAGGGGACCTGACGAACCACGTGCGGTTCCATCACAAAGAGAAGCCGGTGAACTGCGACGTTTGCGGGAAACTCTGCCAGAACAGCGGCTCGCTGTACGTGCACCAGAAGTGGGCGCATTACAAGCCCAAGTACGAGTGTCACATATGCAAACGGCGTATGGTCACGCAGGAGAATCTTGATCAGCACCTGTTGACGCAGCACGAGAAGCGGGAGAAGATCGTGTGCGCGGAGTGCGGCAAGACGTTCACCAAGAAGGACTCGTTTAAGAGGCACATGGCGGTGCACACGGGATGCAAGCCGCATTCCTGCCTGATATGCAACAAGCCTTTCGCGAGGAGGTCCCAGCTGCGTCAGCATCTGTTGATCCACACCGGTAAAAGGCCGTTCGTCTGCGACATATGCGGGAAAGCCTTCACGCAGAAGCCCGGTCTGATCTGTCACAGGAAGACGCACCCGGGGCCGCACCCGCCGTTGCCGGTCATGCCGATCGCCGATATCGTCAAGGAGTTCACCGAAGGATACGTGCAGGAGATCAGCGCGCGCGAAAACGAGGAGAGGATCGAGGAAGAGACGATCCTGGACCCGCTAAGCGAGGAGTTCAAGACCGACTGCCCGATCCCCGGCGTGGAATACGTGGACTGGATCGACAAAGAGAACTTCGAGGTAGCTTCGTTGGGCCAGGACGCCGGGAACAACGGAGGGAAAAGCGACTCGGAATTGTGTTACTCGAACAGTCCGAATCGCCGCGCGAAGAAACGAGTAGCGGCGGCCTGGCTGGAGTGCGACCACTGTCGCCGGAAATTCTTGAAGAAGAGCAACCTCGCGGAACACCTGAAGAAGCACCGGCACAAGTGCGCGGACTGCCCGAAGACGTTCAGGTTGCGACGCTACTTGGCCGCCCACGTCGAGAAGATCCACCGCAGGCAGGTGTACGACTGCAGCGTGTGCGAGTACAAGAGCAACAACAAGGGGACCTTGAAGAATCACTACATCAGGCTGCACACGAGCAACTACAACTTCGCCTGCGACGTCTGCGGCAAGCAGTTCAAGATCAAGAAGGCCTTGAACCACCACGTCAAGCAGAACCACAGCGACGCGCCGCCGATAGTCTGCGACGTATGCGGCCATTTCAGCAAAAACCTCCACGCCCTGAAGGCGCACATGAAGTACAGGCACTACAAGCCGGAGTTCATCTGTCGGATCTGCCGGAGGGGCATGACCACCCAGGAGAATCTGGAGCAGCATCTGACTTGGCACGAGACCAGGGAGAAGGTGCTCTGCCCGACCTGCGGCAAGAGGTTTCGAGGCCGCGACCTTGACTCCCACATGAGGGTGCACACCGGAGTGAAGCCCTTTCCCTGTCCGGTCTGCGGGAAATCCTTCAGGAGGCAGACCGCTCAGGAGCAGCACGTTTTGATTCACACTGGAAAGAGACCGTACGTTTGCGACATTTGCGGGCAGGCTTTCGCGCAGAAGCCGGGGCTGATTTGTCATAGAAAGAGACATCCTGGACCACTGCCGCCTCTGCCTGTCGTGTCCATTAAGAACATCGTGACGGAGTTCACTAAGGAATATACTATGAAGAACACGATGATCAAGATCGATTACCAGGCCGTGAACCCCTTGGCCGACGCGAGGATCATGGAGCGCCGTCGCGACGTCAGAACTGATTCCGACACGGCCAGGCCCAAGAAGATCAGGCCAAAGACTCCAAAGGCTAAACCTATGTTCCTGGAGTGCGACCATTGCGGCAAGCAATTCGACCGGAAGACGCCGTTGATACTGCACATAAAAGAGCACGTGAACCAGTGCAGGTTCTGCGACCAGGGCTTCCAAAAGGCGAAGGACCTGAGGGTGCACGTTCTCGAGCAACACGGGCCGCTGGTCTACCCGTGCCACATGTGCGAGTTCAAGAGCACGAACAAGTGGATACTGAAGGACCACATCATCCGCAGGCACACCACCAGCTACCCTTACACCTGTACAGTTTGCCAGAAGAAGTTCAAGCTGAAGAACGACCTGAAGCAGCACACCAACCAAATGCACAGCGACGCGCCGGCAGTGATATGCTCGGTTTGCGGTCACTCTTACAAAAGCGTGCCCGCGCTTAGGCGTCACATGAGGTACAGCCACAACAAACATCCGTTCGAGTGCAGTATATGCAAACGCTGCCTGTCCACTCAAGAGAGTCTGGAGCAGCACCTGTTGTGGCACAAGGAAAGGGAGAGGGTGGTTTGCCCGACTTGCGGGAAGATACTTAGAGGACGCACCATCGAGGGACACATGCGGGTGCACACCGGTCTGAAGCCTTTCGCGTGCCCCATTTGCGGAAGGTCTTTCACGAGGCAGACCGCCATGGAGCAGCATGTTCTCATTCACACCGGGAAGAGGCCGTACATCTGCGATGTTTGCGGACAAGCTTTCGCGCAGAAGCCGGGGCTGATCTGCCACAGGAAGAGACACCCTGGACCGCTACCACCTTTGCCCGTTGTGTCCGTCAAGAACATCGTGATGGAGTTCACCAGGGACTATAACATGAAGAACACGAACATTGATATCGAGTAA
- Protein Sequence
- MSSLDYLDLCRLCLVKDRASVPIFEGEGDERQIFLKIAACLPVKVAREDKLPKKICDDCVYKVESFYHFWNTTANAEKRLLQCLGEVGVDGGKQGYVSNVFNPNVMKQEQSTENRLDGSVMQQVGEHQNNMGMGMMDNMGLGIPMIMSNTNQQQQITSVPMDTSGSSVQNVQAVPGPSSQTTHNQISQNQTSSTQQEDEEESSEDDENSDDECDGDEGLPVKEESEEDPNSRTIEPTTFVNVSLACDEAGPSGLQQQKIAEMPEMPIPQPADGDPKTGTLNGDGHFIYGKESIPMQPWQIVDVEGCLYYAFLPTSQSLKLSEQEKLGPKSAAELLKLAMDDSKEPFIIPAEEEVSRATSYFNRIKVKSEDDNSSPNEDHHHDVSSSNDHQNDVSSLTEDHQIDASSLNEDHQNDSSLNEDHQNIPSLNEDHQTDDKVYVCEECNICFPVAQMLKRHRNAVHDQAQRYKCKVCFKICRSLVAFKMHVALEHKTEEQELKDENSLTYACNFCSYESTNKSTLHSHISRKHPVKHIGRRKNSYRYTAEPEEYSCDVCEFKCQNRRRLKEHLERKHASEYKYDCEYCGKKFKVKGDMRLHVRFKHKEGPIVCDVCGKTCSNSNSLYVHQKWAHFKPKYECEICKRRMVTQENLDQHILLQHERRESFVCEECGKSFTENHRLKQHMMTHTGDRPYDCHICGKAFARRTAYRQHLLIHTGKRPYICDICGKTFTQKPGLICHRKSHPGVPDPRGIFLYDKESVVMKKWQILEFDGKPYYAFVPEGDTPLLDEEIPEQIEELVEAEEDKQNLVKVECLYNEEELQYHSSEEKLYEDEEHLLNGIAEQRDEEDEDVKPIILNGSIEGENDKIGDLYQVKVQGSMVTIEKLMSTEVDEKKVDYQQDTEEQDIYTEQEQLEQLEEVEDVEETDQLDQIEQVEYLEEEILEAANNHATPTKTRRKISRSTGGALKCKVCSEMFSSAISFRKHVAWTHKKKVCIQEDGAYICAVCDYRTLKKSLFAAHLERKHETWSRKRPNNMLFPCATCGFVCRSKHSLQSHFIRKHTDRYEHQCKFCSKKFKVKGDLTNHVRFHHKEKPVNCDVCGKLCQNSGSLYVHQKWAHYKPKYECHICKRRMVTQENLDQHLLTQHEKREKIVCAECGKTFTKKDSFKRHMAVHTGCKPHSCLICNKPFARRSQLRQHLLIHTGKRPFVCDICGKAFTQKPGLICHRKTHPGPHPPLPVMPIADIVKEFTEGYVQEISARENEERIEEETILDPLSEEFKTDCPIPGVEYVDWIDKENFEVASLGQDAGNNGGKSDSELCYSNSPNRRAKKRVAAAWLECDHCRRKFLKKSNLAEHLKKHRHKCADCPKTFRLRRYLAAHVEKIHRRQVYDCSVCEYKSNNKGTLKNHYIRLHTSNYNFACDVCGKQFKIKKALNHHVKQNHSDAPPIVCDVCGHFSKNLHALKAHMKYRHYKPEFICRICRRGMTTQENLEQHLTWHETREKVLCPTCGKRFRGRDLDSHMRVHTGVKPFPCPVCGKSFRRQTAQEQHVLIHTGKRPYVCDICGQAFAQKPGLICHRKRHPGPLPPLPVVSIKNIVTEFTKEYTMKNTMIKIDYQAVNPLADARIMERRRDVRTDSDTARPKKIRPKTPKAKPMFLECDHCGKQFDRKTPLILHIKEHVNQCRFCDQGFQKAKDLRVHVLEQHGPLVYPCHMCEFKSTNKWILKDHIIRRHTTSYPYTCTVCQKKFKLKNDLKQHTNQMHSDAPAVICSVCGHSYKSVPALRRHMRYSHNKHPFECSICKRCLSTQESLEQHLLWHKERERVVCPTCGKILRGRTIEGHMRVHTGLKPFACPICGRSFTRQTAMEQHVLIHTGKRPYICDVCGQAFAQKPGLICHRKRHPGPLPPLPVVSVKNIVMEFTRDYNMKNTNIDIE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -