Basic Information

Insect: Nomada ruficornis
Gene Symbol: topi
Assembly: GCA_951802695.1
Location: OX637850.1:2801448-2803895[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.3 2.4e+02 2.9 3.9 1 23 249 271 249 271 0.88

2 15 0.26 27 5.9 1.6 2 23 278 300 277 300 0.95

3 15 0.0013 0.14 13.2 0.4 2 21 307 326 306 327 0.92

4 15 0.00052 0.053 14.5 2.4 1 23 334 356 334 356 0.97

5 15 7e-07 7.2e-05 23.5 1.1 1 23 362 384 362 384 0.95

6 15 0.23 24 6.1 5.9 1 23 433 455 433 455 0.96

7 15 0.003 0.3 12.1 1.7 1 23 461 483 461 483 0.94

8 15 0.015 1.5 9.9 0.7 1 23 493 516 493 516 0.94

9 15 0.099 10 7.3 0.0 1 20 530 549 530 551 0.92

10 15 0.0051 0.53 11.3 0.1 1 23 556 578 556 578 0.98

11 15 2.3e-06 0.00024 21.9 3.1 1 23 584 606 584 606 0.98

12 15 0.00015 0.015 16.2 0.4 1 23 612 635 612 635 0.97

13 15 0.056 5.7 8.1 0.7 1 23 641 663 641 663 0.89

14 15 3.7e-07 3.8e-05 24.4 2.2 1 23 669 691 669 691 0.99

15 15 4e-06 0.00041 21.1 5.0 1 23 697 720 697 720 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.3	2.4e+02	2.9	3.9	1	23	249	271	249	271	0.88
2	15	0.26	27	5.9	1.6	2	23	278	300	277	300	0.95
3	15	0.0013	0.14	13.2	0.4	2	21	307	326	306	327	0.92
4	15	0.00052	0.053	14.5	2.4	1	23	334	356	334	356	0.97
5	15	7e-07	7.2e-05	23.5	1.1	1	23	362	384	362	384	0.95
6	15	0.23	24	6.1	5.9	1	23	433	455	433	455	0.96
7	15	0.003	0.3	12.1	1.7	1	23	461	483	461	483	0.94
8	15	0.015	1.5	9.9	0.7	1	23	493	516	493	516	0.94
9	15	0.099	10	7.3	0.0	1	20	530	549	530	551	0.92
10	15	0.0051	0.53	11.3	0.1	1	23	556	578	556	578	0.98
11	15	2.3e-06	0.00024	21.9	3.1	1	23	584	606	584	606	0.98
12	15	0.00015	0.015	16.2	0.4	1	23	612	635	612	635	0.97
13	15	0.056	5.7	8.1	0.7	1	23	641	663	641	663	0.89
14	15	3.7e-07	3.8e-05	24.4	2.2	1	23	669	691	669	691	0.99
15	15	4e-06	0.00041	21.1	5.0	1	23	697	720	697	720	0.96

Sequence Information

Coding Sequence: ATGAACAGCGGAAAAACGGAATCGATGAGCACGTTGAGCGAGCACGAGGACGATCTCGACGATCTCGAGGGGTCAGTCATTTGGTCCCAAGAGGAGCCGCTCTCCTCCAACGAGATCCTAGAACTGACCCCGGATCCAGAGGGGCAGAACCGTTTGAAATCTTTGTGCCGTCTGTGCGCGGGAGAGACTCTCAATCcaatttacatttattccGAGTTCGGCGAGTCCCTGAGACTTTTGCATAAGATCAACACGTGTCTAAGCATTAAGGTAAAGAAAACGGATCCGTTGCCGAAGCAACTGTGCCCGACGTGCGTGGAGAAAGTTAACTGGTGCAACGAGTTCGACGTTCAATGCATCCGAGCCGAGGAAACCCTGTTCGAGATCCTGAAGCAGAAGCATTCGTTCGCCAATAATCCGACCGACGACGCCTCCCAGGAGAACGCAGATTCCTGTCCGCTGTGCGTCGAGGGAAGGATGAGGGTTTACGAAGAGGACAAGGAAGCCAGGCGAGACGTCGAGCTGTACGACAGCGACATTGTTCTGGAAAGCAGCGACGAGGAGCAGATACCGAACGAAATAACAATCGACGAAGAGCCGAACGAGAACGAGGCCATCACGTTGTTCTGTCTGGGCACCAAGCAGAAATATTTGAAGTGCGGGGCGTGCATGAACCTGTATCACACGAAGGAGACCCTGGACGAGCATAAATGCAAGCCAAACCTGCAGTGCACGTCCAAGCCGTACAAGTGTGATGTTTGCTTCGCGACTTTTACGTTCGAGGAGCGACTGCAGTTCCATCAGCATTTCCACAAGGACGCCAAGGCGTTGTACTGCGAGACCTGCAAGATCACGTTCGGGAAAGAGTTGAAACTGTTCTATCATTACAAGAGATATCACTGCAAAGGGGGCAGAGTGTCCTGTTTGCAATGCGGCAAACTATTCGAGAACCAGGATGGTCTGAAGAAGCACGTGTGCGTCGATGGGAAGACAAGACCGCACGTGTGCGAGGTCTGCTCCAAGGGATTCTGCGACGGGTACACATTGAAGCGACACGTGGTCACTCATCTGCCGGAGAAGCCGTTCAAGTGTCCTGAGTGTTCGAAGAGTTTCACACAGAAATCCAGGCTGAACAAACACGTGGCGGGCCACAGTATAACATTCGAGAATAACCAAACAATTTGGAGGTGCGTTCGCTGCGGCGAAGCCTTCGGCAGCTGCGAGTCTGCGGACGAGCATTGCAAAAAGCACGAGGAGAAGATCAGTCTAATCGAGGAGTTACAAGTGTTGAAGCTGTACCACTGCGAATTCTGCAGCAGCCACTTCGCCGACATGGATCATCTGAAGAGCCACAGGGAATTGCACGTGGTGGAGAAACCGTACACCTGCAACCACTGCAACACCACGTTCAAATCGTTCGCGGAGGCTGTCCTCCACTGGAAGGAGCACCCGAGGATATTCAAGGTGCTGGTGGTGTTTCTGTGCGAGATATGCGACAGGGACGTGAAAGAGCTGTCCCTGCTCTACAAGCATAAACAGAAGCGGCATCAACCGGTGGCCAGAAGATCCGAGAGGAGCAAAGAGAAGTTCATCTGCGAGCTATGCGGTGGCGTGTTCGCGAGCATCGAGGACTTTCAGGAGCATGGGAAATATAGATGCTCGAAATTCCCGTGCGACATCTGCGGCAGCCTGTTGCCGACAGCGAATTCCTTGAACGCGCATAAAAGACGGCACAGCGGATTGAGACCATACGTTTGCAACATCTGCGGGAAAAGTTACACGCAGTCCAGCCACATGTGGACGCACAAGCGATTTCACATGGGCGTGAAGCCGTACGCTTGCGAATACTGCGACCAACGGTTCACGATAAAACCCGACCTGGCCGATCACACCAGGAAGAAGCATACCAGGGAACGGCCGTTCAAATGCGACGTTTGCAACAAAGCTTTCTTGACCGGGTCCGTGTTCTATCAGCACAGACTGATACACAGGGGGGATCGCAGATACAAGTGCCACTACTGCGAGAAAGCGTTCACCAGAACGGAGGCGCTGAACAATCACATAAAAATTCACACCGGCGAGAAGCCGCACGCCTGCGACATTTGCGGCAGGTGTTTCAGGCAGAAAGGGGACATGAGGAAGCACAGGAGGACCCAGCACACCGTTAAACAGGACGCCAAATAG
Protein Sequence: MNSGKTESMSTLSEHEDDLDDLEGSVIWSQEEPLSSNEILELTPDPEGQNRLKSLCRLCAGETLNPIYIYSEFGESLRLLHKINTCLSIKVKKTDPLPKQLCPTCVEKVNWCNEFDVQCIRAEETLFEILKQKHSFANNPTDDASQENADSCPLCVEGRMRVYEEDKEARRDVELYDSDIVLESSDEEQIPNEITIDEEPNENEAITLFCLGTKQKYLKCGACMNLYHTKETLDEHKCKPNLQCTSKPYKCDVCFATFTFEERLQFHQHFHKDAKALYCETCKITFGKELKLFYHYKRYHCKGGRVSCLQCGKLFENQDGLKKHVCVDGKTRPHVCEVCSKGFCDGYTLKRHVVTHLPEKPFKCPECSKSFTQKSRLNKHVAGHSITFENNQTIWRCVRCGEAFGSCESADEHCKKHEEKISLIEELQVLKLYHCEFCSSHFADMDHLKSHRELHVVEKPYTCNHCNTTFKSFAEAVLHWKEHPRIFKVLVVFLCEICDRDVKELSLLYKHKQKRHQPVARRSERSKEKFICELCGGVFASIEDFQEHGKYRCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDICGRCFRQKGDMRKHRRTQHTVKQDAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00085636;
90% Identity: iTF_01417868;
80% Identity: -