Basic Information

Insect: Nomada hirtipes
Gene Symbol: Bcl11b
Assembly: GCA_951802735.1
Location: OX637930.1:2750121-2768707[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0071 0.73 10.8 0.2 2 23 183 205 182 205 0.95

2 6 2.2e-07 2.3e-05 25.0 1.5 1 23 522 544 522 544 0.98

3 6 0.00032 0.033 15.0 0.3 2 23 565 587 564 587 0.97

4 6 1.2e-07 1.3e-05 25.8 2.9 2 23 790 811 789 811 0.97

5 6 8.8e-06 0.00091 20.0 3.3 1 23 817 839 817 839 0.99

6 6 4e-05 0.0041 17.9 0.4 1 22 847 868 847 868 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0071	0.73	10.8	0.2	2	23	183	205	182	205	0.95
2	6	2.2e-07	2.3e-05	25.0	1.5	1	23	522	544	522	544	0.98
3	6	0.00032	0.033	15.0	0.3	2	23	565	587	564	587	0.97
4	6	1.2e-07	1.3e-05	25.8	2.9	2	23	790	811	789	811	0.97
5	6	8.8e-06	0.00091	20.0	3.3	1	23	817	839	817	839	0.99
6	6	4e-05	0.0041	17.9	0.4	1	22	847	868	847	868	0.97

Sequence Information

Coding Sequence: ATGGAAATTACGAAGACTGTTGCAATAAGGGAGCCACGCGGTGCAGTGATCGAGGCATTACGGATGTATGGGCCAATTTCGGAAACCTCGCAAGGCACCACATCCCCAGACACCGTCCAATGCGGGGCATGCAGGGTGTCCTACCCCCTTGGCGAGATCGTGCGGTTCATCGAGCACAAGGTGAACCACTGTCGCAGCTCACCTCAGGGCTGCCACAGTCCACCGGCCACAGCGGCGCCAGAGGACTCCGATCCCGAGGACGCGCTCGCCCTAAAAACTGCCGATCAGGACTCGAAATTGAACTCGGTGCCCAGCATCTCGGCGCCTATCAACAAAAGGGGCGGAGGCAGGCTAGATAGTCCACCGACGCCTCAGGGCTCGGGACCGGACGCTGGTAGTCCGATCGAGCTGAAAGCCAGCGCTAGCTCGACGCCCAAAAGACGAACAGAGGCTTCCGACGAGGACAAGGAGGACATACCGAAGAAACAGAAAACGGAGTCCGTGGACGCAGACACGAACACGGTCAATTCTGAACCAAGATGGCTCCAGTGCTCGCAATGTTCCAGGAGACTATCCTCCGCCTGGGAACTCCTGCAGCACGTGCAGAGCGTGCACGGTGCACGCCTGTACACCTCTCCATCATCCTCGACGAATTCATCGTCGAACACACCCGCGCCGAGTCCAccgacgccgacgccgacgCACACTCACCATCTAAGTCCGCCGAATCACCTGAACCTGAGCAGCAAGTCCACCGGGAGTTCCTCCGCAGGAAATTCCTCCGGTGGTACGAACTCCAGCGGGAGCAGCGGCAGTCGACAGCAACTCCAATCCTCCACCTCCCTCGTCGGTGATCCGCTGCACAGTTTTCTCAGGCTACCTCAACACCTAGAACGAAGTTTTCCACCGATGTTCAGGCCCGACTTCCTCGCCCTGAATCCGCTGGCCGGGTACAGAGGCCTTCAGGAGCTCCAAACCGCCACCAGGAATCTACAAAACCTCGGTGATCCTCTTCGAGGAATGGACGGTTTGAATCTGGGGGACCCACTGGTCCGTAGCTCGTTGGACTCCTTAAACAACGCCAGAAACTTGGCAAACCTGGCCGAATTGTCGCACGGCCGTGGTCTAGCCGGTCAGGCGCATCCCCCTCCACTTGAGGCCAACCTGGATTTTTACTCGGCGCGCCTAAGGAGCCTCGCTAATCCGTCCTTAGGCGCGGCTCCACCTAGTAGCGGTAACTCTACCACGAATACAAATCCTCCAGCCCCAGTGCCACCCGTACCTGTGCCAAGCACCGtccaacagcagcaacaacaacagcaacagcaacaacagcagcagcagcagccgGCACAGAATCACAGCCAACCGATTCAACCATCGAGCCCGGCGTCGAACAACACGATACTGATCCACAATAATCATCAGAAGGAGAACTCGCCGCCCTGTTACAGCCAGAGCCCCGTCGGccatcataataataataactcgaCCGACAGCGAGAAAGCTAGTCCCCCGGTTGCCTCGACGCCCATAATCACCGATTCCGCGTCGGAGACGATCTACTCTTGCGAGGTGTGCGACAAGAAGTTTCGCTTCCAGTCGAATCTGATAGTGCACAGGAGGAGCCACAGGGACAAGGAGAGACAGTATCAACAGGATGGCACGCAGGATGGACAGAAAACGCCGACGAGGTGCGAGGTCTGCGAAATGGAAGTCACCAGTTACGCGGAGTTAAGGAAGCACATGAGAAAGGAGCACCAGGAGAGTCTGAACGCGGCCAGTCCTCAGGGCAGCGTCGAAACCGTTCCGGACGACGGTTCCAGCTGCGACGAGAACATGGATCTCGACGATGCCGACGAGAACGACCACAAAGGGGACAGGGAGGACACGGAGGAGAACACTCCGGAGGATCTGAGCACCACGCAGGGTCAAAGTGGGGAGGAAAGTAGCGGTCGCGTGGAACAGAAGCCAGCCAGCCTGGTCGGCGATCTGATGGAGAAATTCGGATTGAGCAACATAGCGCAATACTCCGAGGCGTACAGGCAGGCTCTGCAGGAGAATCATCGGGGCGGTTTCATCAAGACGGAGTCCCCGTCGAATCTCACCAACTCTCTGAACAACAACAAGGAGAAGGACAGCGCGCTGTCGCCCACGAACTTCAATTCCTCGACCACGCCTAACATATTCTCCGGTCAGGGTTTTCCCAGGTCGACTGGCCCGGACTTCGGCGGCCTGTGGCTGCCCAATCCTCACTATCTCGAGAACAACGAATTCCGCAAGGCAACCAAGGCCACCACGTCTAGCCTGGCACTGCAGGGTCTACCCAGCCCGCTGCTGAAGAAGGAACGCAGCGGGAGGAACGACACGTGCGAGTACTGCGGCAAAGTGTTCAAGAACTGTTCGAACCTGACGGTTCACAGGCGGTCTCACACAGGCGAGAAACCGTACAAATGCGAGCTGTGCTCGTACGCTTGCGCCCAGAGTTCCAAACTGACCAGGCACATGAAAACCCACGGCAGACACGGCAAGGATACGTACAAGTGTCGCTTCTGCGAGATGCCGTTCTCGGTGCCCAGCACGCTGGAGAAACACATGAGGAAGTGTGTCGTGGTGGTGCAACAGGGCCCCAAATTGGGAATGCCGTATCCTGGTAGCCAGGACGAGGACTCGTCGTTGAGTACGAAGGATACTTGA
Protein Sequence: MEITKTVAIREPRGAVIEALRMYGPISETSQGTTSPDTVQCGACRVSYPLGEIVRFIEHKVNHCRSSPQGCHSPPATAAPEDSDPEDALALKTADQDSKLNSVPSISAPINKRGGGRLDSPPTPQGSGPDAGSPIELKASASSTPKRRTEASDEDKEDIPKKQKTESVDADTNTVNSEPRWLQCSQCSRRLSSAWELLQHVQSVHGARLYTSPSSSTNSSSNTPAPSPPTPTPTHTHHLSPPNHLNLSSKSTGSSSAGNSSGGTNSSGSSGSRQQLQSSTSLVGDPLHSFLRLPQHLERSFPPMFRPDFLALNPLAGYRGLQELQTATRNLQNLGDPLRGMDGLNLGDPLVRSSLDSLNNARNLANLAELSHGRGLAGQAHPPPLEANLDFYSARLRSLANPSLGAAPPSSGNSTTNTNPPAPVPPVPVPSTVQQQQQQQQQQQQQQQQPAQNHSQPIQPSSPASNNTILIHNNHQKENSPPCYSQSPVGHHNNNNSTDSEKASPPVASTPIITDSASETIYSCEVCDKKFRFQSNLIVHRRSHRDKERQYQQDGTQDGQKTPTRCEVCEMEVTSYAELRKHMRKEHQESLNAASPQGSVETVPDDGSSCDENMDLDDADENDHKGDREDTEENTPEDLSTTQGQSGEESSGRVEQKPASLVGDLMEKFGLSNIAQYSEAYRQALQENHRGGFIKTESPSNLTNSLNNNKEKDSALSPTNFNSSTTPNIFSGQGFPRSTGPDFGGLWLPNPHYLENNEFRKATKATTSSLALQGLPSPLLKKERSGRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRHGKDTYKCRFCEMPFSVPSTLEKHMRKCVVVVQQGPKLGMPYPGSQDEDSSLSTKDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01454407;
90% Identity: iTF_00088302;
80% Identity: -