Basic Information

Insect: Nomada fucata
Gene Symbol: mecom-b_1
Assembly: GCA_948146005.1
Location: OX411276.1:30478579-30504243[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.082 5.4 7.3 0.2 2 22 318 338 317 340 0.88

2 9 0.24 16 5.9 0.2 1 23 347 370 347 370 0.93

3 9 1.2e-05 0.00079 19.4 0.4 1 23 376 403 376 404 0.91

4 9 4.8e-06 0.00032 20.7 2.6 1 23 410 432 410 432 0.95

5 9 2.9e-05 0.002 18.2 5.0 1 23 438 460 438 460 0.99

6 9 0.00058 0.039 14.1 0.7 2 21 468 487 467 488 0.95

7 9 6.9e-09 4.6e-07 29.6 1.2 1 23 844 866 844 866 0.99

8 9 3.6e-07 2.4e-05 24.2 1.7 1 23 872 895 872 895 0.97

9 9 1e-05 0.00068 19.6 3.4 1 23 901 923 901 923 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.082	5.4	7.3	0.2	2	22	318	338	317	340	0.88
2	9	0.24	16	5.9	0.2	1	23	347	370	347	370	0.93
3	9	1.2e-05	0.00079	19.4	0.4	1	23	376	403	376	404	0.91
4	9	4.8e-06	0.00032	20.7	2.6	1	23	410	432	410	432	0.95
5	9	2.9e-05	0.002	18.2	5.0	1	23	438	460	438	460	0.99
6	9	0.00058	0.039	14.1	0.7	2	21	468	487	467	488	0.95
7	9	6.9e-09	4.6e-07	29.6	1.2	1	23	844	866	844	866	0.99
8	9	3.6e-07	2.4e-05	24.2	1.7	1	23	872	895	872	895	0.97
9	9	1e-05	0.00068	19.6	3.4	1	23	901	923	901	923	0.99

Sequence Information

Coding Sequence: ATGAGCGGTCTCGATTTGTCCCGGCCGATGGTCGACTGCAAGATGAACGGAAGCAGCGACGAAGGAGAGTCGACGTCGAGCGCGTCGGCCGGTGGAGGAGGCCCGGGAATCGGCGAGAACCAGGAAATGGAGGAAAACGGCACGATCCGTGCCAGCGGCAACAGTTCCGCCGGCAATTCCGTCTACAGTGACCTGAAGGCCCTTCGAGCGACCAGTGCCCACGACGTGCCTCAGGATTATAATCCGCAGTCGAGGCCTGCTTATCAGCGCGGCTATTCACCTGCCATGGACAAGCAGCCGCTGAGCTACGAGAAGGAACAGCACGGTATACCATCGTTCAAGGAAGAAGAGAAATCCTCGTGGGACTACATAGAGAGAGCCGACAGAAAAGAGTACTCGAGATCGCAGGACGCCGCCTATAGGGACGACGTGTACCAGGACGAGACGAAGCAAGAGCAGAAGGATCAATCGTTCGGGGAGTGGGTGTCACCGGTGCCGGAGGTGGAGGTGGGAGGTTCGGCGCTCGGAGGACCTCAGGTTCGAGCACGGAAGGACGTTCCACGAGGCGCGAGGTTCGGTCCTTTCCTCGGGAAATGGGCGAGCGAGCCATTCAACCCCCGTTACGCGTGGGAGGTCCGCACATCCGGCACCGGGGTCAGGGGATGGCTGGACGCATCCCACGAAACGAACAATTGGCTGAAGTATGTTCGAAGCACCGGCAATCCGCATGCAGTTAACATGAGACACGTGCTGATCGGTGGACAGATGGTGTACGAGGCGGTACGAGACATAGCGGCGGGTGAAGAGCTGCTTCTCGGTGTTCGAGAACCTCTTCAGCTCCAGGACATGCTCGGCGAAAATACCACCGAGGATAGAAGCGACCGAGAGACCGCCTCGCAACACAGCGGCACCGTCGACGAAGACAAAGAGGACGAAGAGGAAGGCGAGACTAGATGCGCCGTCTGCGACAAACCGTTCCAAGACATCGAGCTATTGGACAATCACCTGGTTGCCTGTCATAAATACCCGGCCGAACAGCACCGCTGCGACAGCTGTCCGCGATCCTACGCCTGGCGACCGCTGCTGGTACGTCACCGTGCGATCGTTCACGGCGATCTGCGAAACTACGCCTGCGAGAACTGTCCAAAGTTGGACAAACCGCaggtctttaccgatccgtcgaatcttcaacgccacatcaggacgcatcacgtgggcgccaggagtcacgcgtgcaccgagtgcggaaagacgttcgccaccagctcgggcctgaagcagcacacccacatccacagcagcgtgaagccgttccagtgcgaggtctgcttcaaggcgtacacgcagttctcgaatctatgccggcacaagcgtatgcacgcggactgccgtatgcagattaagtgcgtcaaatgcggacagtccttcagcacggtcacctcgctgtccaagcataaacGATTCTGCGACTCGACGCCGCCGACTGGCCCACCTGGCGCCATGCCTCAGTTACCAACCTCGGCGCCCAGCCCTTTCCTCGTCTATCCCAGACCGCCCGTCAGTCTTCCCGGTGGCTTGCCCTTCTATCCTCCGAGTTTGATGGGACCCTATCCTGGAATATTTCCGAACGCTCCCAACTTTTTGAACACGCCCCTCCTATTCCCACCGAAGATCGAGGAAGCTGAGAAGAGGAGCGACAGCCCGAAAAAGGAGCGCTTCACGCCGCCAAGAGTGCTGCCGCAGCACAGCAAAGTTTCTCCATCCACCGCGGAGGAGGCCACGTCATCCTTCAGACCATCCCCCGCTAGACCGCCGGTCCAGCCCACTCCGGAGAGCGACGACGATCCCTCGAAGAAACGCAAACGCTGCAGAAACACCGAGAAGGAAGCCGAAGCTGACCACGCATCGGCGTCCACGAACGAGGAAACCACGGATCAGCCGCTGGATCTGAGAGTTCAGACGAAGAAACAGAAGGCCGCTCCGAGTAGCGCCGCTGAAAGAAGGAGCCGTAGCCATTCGCCGCCTCCGGCACCCATGGACGCCTCTCCGCCACCCCCGGAGCCTCCGAAACCGGAAGAGGAACAATCTTTGCAGATGAAAGTCGAATCCAAGGATGTGCCCAGCAGTCCACATTTGAGAACGACTCTGCCCACCGAACAGCCTCCGACAAACACTCCGCCTCACATGGCCTACCCTAGACCGATTCATCCCAGCTTTCTCGAGGCTATGTATCGCGGACCAGCCGGCGGATTTCCCGGTTTTCCCGGCGGCCCACCACCACCCGCTGGAGTCACAGCCGATTCCAGGTTACTGCCGCCGCTACCACCGTTCGGACCACCGCGCGGACTTCCTTTTTTAGGCACCCTGATGAACGGACTCGGCGGCGCTAGGCCAGGAGCCGGAGGATTCGATCTGCTCGGCAGGCCGCCGCTGGGACCGTTCCCCGGCGTGAAGCCGTTTCAGGAAGCGGTAATGGCCTCGCATCATCACCACCATCATCACCATGcccacggcaagatgaaggatcggtactcctgcaaattctgcggaaaggtattccccagatccgccaatctgactagacacttgcgcactcacaccggagagcaaccgtacaaatgcaaatactgcgagaggtcgttcagcatctccagcaatcttcagcggcacgtgaggaacattcacgataagcagaggccgttcaagtgtccgctgtgcgagaggtgtttcggacagcagacgaacctggacagacaTCTGAAGAAGCACGAGGCCGACGACGGGAGCGGGGTCGTTTCCGTGGCAGATTCCCCGGGGAGTAGCAACGAGAACGAACGAGAAGATACGTATTTCGATGAGATCAGGTCGTTCATGGGAAAGGTGACCTACGGCGGCGAAGCTGGATACGGGTTGCCACCGCATCCAGCTTACCTGCCCAGTCGACTTCACGAGATGAACGAGTCCAAGATGGAGACCGAGTACGACGAAGATGAAGACAGCGAGGAGGGTGTCTCCCCTCTGGACGAGGCCGACGCTCTGTCGCCGGTCGAGGGCAAGGAATCGACGCCTCCGCCGCAGTACGACCTGAAGCATCGAGAGAAGCAGGAACTCCTCAACAATAACACGGCGGAGCCTGTCATCGAGATCTCCACATAG
Protein Sequence: MSGLDLSRPMVDCKMNGSSDEGESTSSASAGGGGPGIGENQEMEENGTIRASGNSSAGNSVYSDLKALRATSAHDVPQDYNPQSRPAYQRGYSPAMDKQPLSYEKEQHGIPSFKEEEKSSWDYIERADRKEYSRSQDAAYRDDVYQDETKQEQKDQSFGEWVSPVPEVEVGGSALGGPQVRARKDVPRGARFGPFLGKWASEPFNPRYAWEVRTSGTGVRGWLDASHETNNWLKYVRSTGNPHAVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCAVCDKPFQDIELLDNHLVACHKYPAEQHRCDSCPRSYAWRPLLVRHRAIVHGDLRNYACENCPKLDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTSAPSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGIFPNAPNFLNTPLLFPPKIEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKRKRCRNTEKEAEADHASASTNEETTDQPLDLRVQTKKQKAAPSSAAERRSRSHSPPPAPMDASPPPPEPPKPEEEQSLQMKVESKDVPSSPHLRTTLPTEQPPTNTPPHMAYPRPIHPSFLEAMYRGPAGGFPGFPGGPPPPAGVTADSRLLPPLPPFGPPRGLPFLGTLMNGLGGARPGAGGFDLLGRPPLGPFPGVKPFQEAVMASHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMNESKMETEYDEDEDSEEGVSPLDEADALSPVEGKESTPPPQYDLKHREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_01067784; iTF_01066443; iTF_01065740; iTF_01068473; iTF_01069851;
80% Identity: -